Topamax Lawsuits

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The epilepsy and migraine drug Topamax, which is also available as generic topiramate, has been associated with an increased risk of major birth defects. Research has found higher than expected rates of babies born with cleft lips, cleft palates, genital defects and other birth malformations when the drug is used during pregnancy.

TOPAMAX LAWSUIT STATUS: After a string of court losses, the makers of Topamax agreed to settlements for undisclosed amounts in about 76 Topamax birth defect lawsuits.


MANUFACTURER: Topamax is manufactured by Ortho-McNeil Neurologics, a subsidiary of Johnson & Johnson. Generic Topamax versions have been available since 2006.

OVERVIEW: Topamax (generic topiramate) was first introduced as a medication to treat epilepsy, which is a neurological disorder characterized by recurrent, uncontrolled seizures. In 2004, the FDA approved Topamax for an additional use of treating migraines, and it has since become one of the most widely prescribed migraine medications in the United States. The drug is also often prescribed off-label to treat bipolar disorder.

TOPAMAX BIRTH DEFECT SIDE EFFECTS: In March 2011, the FDA issued a warning that Topamax side effects may increase the risk of oral cleft birth defects, such as cleft lip and cleft palate, among babies born to mothers who took the drug during the first trimester of pregnancy. As a result of inadequate warnings previously provided, many women were not aware they may be exposing their baby to a potential risk of Topamax birth defects.

The FDA has urged doctors to avoid giving Topamax to pregnant women or women who are of child-bearing age and at a high risk of pregnancy. Alternative epilepsy drugs may not carry the same risk for the unborn child.

In July 2008, a small study published in the medical journal Neurology identified a potential link between the use of Topamax during pregnancy to an increased risk of serious birth defects. Children born to women who used Topamax during pregnancy were found to develop a cleft lip or palate at a rate 11 times hirer than would be expected in the general population. The study also indicated that children exposed to Topamax developed genital defects at a rate 14 times higher than would be expected.

The FDA required new warnings in 2011 after data from the North American Antiepileptic Drug Pregnancy Registry found that children born to mothers who took Topamax during the first trimester of pregnancy experienced an oral cleft about 1.4% of the time, compared to a prevalence rate of between 0.33% and 0.55% associated with other epilepsy drugs.

TOPAMAX CLEFT LIP AND CLEFT PALATE LAWYERS: Potential lawsuits and class action claims are being reviewed by Topamax lawyers as a result of the drug makers’ failure to adequately research their medication or warn about the potential risk of cleft lip or cleft palate when Topamax is used during pregnancy.

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  1. Johnna Reply

    I was prescribed Topamax as a preventative for migraines by my neurologist.
    I have taken Topamax for probably the last 20 from 500mg to 100mg over the years years.
    I have been in hell and going to doctor after doctor and because I don’t know what is wrong with me or what to do? Recently diagnosed with neuropathy and

    I difficultly with processing of information, slower thinking, difficultly planning and learning.
    Horrible word recall, remembering where I am going in the car, mental fatigue, vision changes.
    Hands and feet issues
    numbness, tingling in my hands and feet, my feet feel wet, the carpet feels wet, shoes feel wet,(I’m Not diabetic)
    All over body aches
    Stiffness and weakness in back and neck, joint pain, mobility problems with balance And vertigo. Pain deep muscle pain, muscles weakness. Bone pain,
    Shooting burning pain, pins and needles in various places of my body, Depression and anxiety issues.
    Sexual problems difficultly with natural lubricant, difficultly Now to reaching orgasm, less or (Non existent interested) in sex than before.
    Bladder control empty the bladder completely. UTI so severe I was in the ER. Bowel issues with constipation.

  2. Haley Reply

    I started having migraines very frequently my freshman year of high school. My pediatrician recommended for me to go see a neurologist as my mom and aunt both have chronic migraines. I was prescribed 25mg of topiramate when I was 15. The dosage was upped to 50mg when I was 16 due to it not fully eliminating my migraines. At first the medicine worked wonders and I had no serious side effects and I felt like my life was improved. Then I noticed my weight began to fluctuate and I started to have neuropathy in my hands and feet. I’m currently 17 and still on topirimate (hopefully off of it soon). The past year and half has been a nightmare due to side effects and I’m just connecting the dots to it being topiramate. I’ve had terrible joint pains in my knees which isn’t common for an active 17 year old. I’ve been to urgent care and my pediatrician with acid reflux and what we thought was gallbladder issues. I’ve had times where my vision goes blurry randomly but quickly comes back. Recently the neuropathy in my hands and feet is getting so terrible it will sting and burn for long periods of time. My neurologist told me this could happen but to just drink water and it will go away. Drinking water does not help this. I’ve also had an increase in dental issues and now my headaches have been happening more frequently. I have also had mental health issues and I thought it may have been because I am a teenager but it was much more prevalent after I started to taking topiramate. I’ve had issues with constipation and bowel movements and I’m beginning to wonder what has this medication done to my body. I have a neurology appointment next week and I do not want to be on topiramate any longer.

  3. Amanda Reply

    I was put on this 4 year ago to help with my migraines was only on it for about 3 weeks if that and ended up coming home from work and falling to the floor and rushed to the hospital from not being able to breathe I had found out that I had 3 blood clots in both of my lungs one the size of a baseball and the other 2 were the size of golf balls. I could have died now I as so scared to take anything for my migraines.

  4. Rachel Reply

    I took topomax for some length of time around 2007-2011. I would have to get medical records to know exactly dates. This was treatment for migraines. Initially, the meds seemed to work but I began having issues with extreme weight loss, fatigue, kidney stones, uti’s ( was hospitalized three times but suffered for years from repetitive infections including sepsis. At some point, suicidal ideation became prevalent, i began experiencing visual hallucinations, lost my peripheral vision on top of rapid onset eyesight issues. It became so bad, I could not drive or walk. Experienced neuropathy, white matter brain disease, suffered a TIA wherein I had to learn to walk and talk all over again. My masters degree was no longer useful because I could not form words, spoke words backwards, high levels of anxiety etc. By 2012, I had to stop working. I have chronic kidney disease, auto immune issues, carotid artery disease, interstitial cystitis, bladder issues, continued migraines, weakness and numbness in limbs, neuropathy etc. I have dealt with this for almost 10 years. Topomax ruined my life. My urologist took me off the medicine stating my urological issues were due in large part to the medicine. I not only suffered loss of work, but incurred a lot of medical bills and have paid for a private neurologist out of pocket to get help just to function on a low level. Stress brings on symptomatic problems. I have stenosis in my neck. I could go on and on. This is a dangerous drug I wish I had never taken. My life was charged forever.

  5. Andrea Robin Reply

    I am 70 years old and I have had chronic headaches every day of my life since the year 2000, aproximately.I too started out low 25 mg. of Topamax but was gradually over the years bumped up from 25mg. to 800 mg . a day.I feel like my life has been robbed so many of the things I once did I can no longer do. I forget terribly, I can’t spell anymore, I can’t add except with calculator anymore, Constipation, I had kidney stones, throw up a lot because I am so nauseated all the time, I have lost a lot of my hearing, my sight has gotten much worse,I simply can’t even do my housework as well anymore for many years.Please Topamax is a very dangerous drug and I am so regretful of ever taking any amount of this drug. My problems are far too many to even list.Someone help us get compensation.

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