Progressive Multifocal Leukoencephalopathy Lawsuits
The rare and potentially fatal brain disease, Progressive Multifocal Leukoencephalopathy has been linked to the use of several medications. Potential lawsuits are being investigated by lawyers for individuals who have been diagnosed with the neurological disease after taking the organ transplant medications CellCept or Myfortic, or the multiple sclerosis drug Tysabri.
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OVERVIEW: Progressive Multifocal Leukoencephalopathy (PML), which is also known as Progressive Multifocal Leukoencephalitis, is a rare viral disease that affects the central nervous system. It causes progressive damage or inflammation of the white matter of the brain at multiple locations and often has fatal consequences. There is no known cure for the disease, but in some cases it does slow or stop if the immune system improves. It often occurs in those with immune systems suppressed by disease or medicines.
Symptoms could include:
- Weakness
- Paralysis
- Vision Loss
- Impaired Speech
- Cognitive Deterioration
- Death
MYFORTIC AND CELLCEPT SIDE EFFECTS: Organ transplant medications Myfortic and CellCept side effects have been associated with the development of Progressive Multifocal Leukoencephalopathy.
In April 2008, the FDA issued an early communication regarding an investigation into a possible association between the use of CellCept (mycophenolate mofetil) or Myfortic (mycophenolic acid) and PML after postmarketing data idenfied several reported cases of the potentially fatal brain disease.
In June 2008, the Roche (the maker of CellCept) and Novartis (the maker of Myfortic) announced changes to the Warnings and Adverse Reactions sections of the drugs’ prescribing information about the association with PML.
TYSABRI SIDE EFFECTS: The multiple sclerosis drug Tysabri (natalizumab) has been linked to several cases of Progressive Multifocal Leukoencephalopathy since it was introduced in 2004. After three reports surfaced of users developing the brain disease, the manufacturers temporarily withdrew Tysabri from the market in 2005. Two of those users died as a result of the disease.
The manufacturers re-introduced Tysabri in 2006 with stricter guidelines for usage and more prominent warnings about the potential Progressive Multifocal Leukoencephalopathy side effects.
In August 2008, additional reports were disclosed of two new cases of PML among users of Tysabri. These were the first known reports sincce the drug was put back on the market in 2006. These reports, which involved users who were taking the drug for at least 14 months without any simultaneous use of another multiple sclerosis drug, renewed concerns about the extent of the Tysabri Progressive Multifocal Leuokencephalopathy risk.
Pingback by Warning Added for Progressive Multifocal Leukoencephalopathy to CellCept and Myfortic — AboutLawsuits.com on 1 July 2008:
[...] Progressive Multifocal Leukoencephalopathy (PML), which is also known as Progressive Multifocal Leuk…, is a rare viral disease that causes progressive damage or inflammation at multiple locations in the brain. Symptoms could include weakness, paralysis, vision loss, impaired speech or cognitive deterioration. Although the disease does slow or stop in some cases with improvements in the immune system, there is no known cure and the disease is often fatal. [...]
Pingback by CellCept Lawsuits — AboutLawsuits.com on 1 July 2008:
[...] between use of CellCept and the development of an often-fatal neurological disease, known as Progressive Multifocal Leukoencephalopathy. In June 2008, information was added to the Warnings and Adverse Reactions section about [...]
Pingback by Myfortic Lawsuits — AboutLawsuits.com on 2 July 2008:
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Pingback by Tysabri Linked to Two More Cases of Progressive Brain Disease : AboutLawsuits.com on 4 August 2008:
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Pingback by Tysabri Lawsuits : AboutLawsuits.com on 4 August 2008:
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Comment by Bessie on 20 August 2008:
I was told I had wegeners granulamatosis referred to a physican put on cellcept by aphysican who did not go over the side effects I blindly trusted him and his association to his hospital name, he explained no side effects and I complaine about my sore throats and about the pain in my head and the MRI that showed positive white matter I complained of sore throat frequently.ther is much more and I am too tired to go into it . A pharmacist told me the drug I was on was dangerous and I had better get someone to listen to me that the cellcept would kill me if I was reacting to it. I call ed immediately and said I would call channel 2 news if no one listened I told them what the paharmacist daid and they discontinued it. I have not gotten better after 3 weeksno response
Pingback by FDA Informs Doctors of Reports of Progressive Multifocal Leukoencephalopathy (PML) from Tysabri : AboutLawsuits.com on 26 August 2008:
[...] PagesTysabri Linked to Two More Cases of Progressive Brain Disease Tysabri Lawsuits Progressive Multifocal Leukoencephalopathy LawsuitsWarning Added for Progressive Multifocal Leukoencephalopathy to CellCept and Myfortic CellCept [...]