Asthmanefrin and EZ Breathe Atomizer Problems Result in FDA Warning

Federal regulators have issued a warning about reports of problems involving a new over-the-counter bronchial asthma drug, known as Asthmanefrin, after several people have indicated that they experienced severe side effects.  

The FDA issued a safety alert on September 30, warning patients about the potential side effects of Asthmanefrin, an inhaled asthma medication used for temporary relief of mild bronchial asthma symptoms.

Several complaints concerning the Asthmanefrin were filed with the FDA since the drug entered the U.S. market in September 2012. According to the federal regulatory agency, patients have reported experiencing chest pain, nausea, increased blood pressure and heart rate, as well as coughing up pink colored sputum.

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Asthmanefrin, manufactured by Nephron Pharmaceuticals Corp., is an over-the-counter asthma medication which contains racepinephrine and has not been evaluated by the FDA under the new drug application (NDA) guidelines.

It is sold in starter kits with the EZ Breathe Atomizer, which was recalled last April because of problems associated with a manufacturing defect. The atomizer converts the asthma solution into a vapor for delivery. The kits contained 10 filled vials and an atomizer, but are also sold in refills of 30 vials.

The EZ Breathe Atomizer recall was issued because a washer in the atomizer packaging could become dislodged during use, putting patients at risk of accidental choking or swallowing.

Although no injuries were reported as a result of the recall, which involved nearly 250,000 atomizers, it was categorized as a Class I Medical Device Recall, which is the most serious type of recall and is only issued when the potential for a product to cause serious health problems, or even death, may occur. The atomizer was sold to Nephron by Health & Life Co. Ltd., a health manufacturing company based in Taiwan.

The FDA warned patients of the potential health risks of the product and will consider a potential NDA evaluation of inhaled asthma products by holding a meeting in early 2014.

“In light of FDA’s concerns about the use of OTC racepinephrine and similar drugs for the treatment of asthma, FDA has decided to give further consideration to the general question of whether inhaled products intended for the treatment of asthma should be evaluated only pursuant to the new drug application process,” the FDA said in a press release.

55 Comments

  • MarkDecember 12, 2020 at 4:03 am

    I have been waiting to see if anyone else experienced irregular haertbeat after using this product? I certainly have since Ibwas forced to use it when they discontinued Primatine Mist Inhaler. To this day I experience at random times for no reason irregular heartbeats.

  • TedApril 3, 2017 at 4:43 am

    Fda epa all govt agencies that put there nose up our ass can all go to hell they can take a long skinny stick and stick it up there ass sincerely ted

  • davidJanuary 18, 2017 at 11:31 pm

    i have used this product for a while for emergency's i found it worked pretty good. but it did make me a bit jumpy after. but so does the atomizer that they give you in the ER. which is where us asthma suffers end up due to the fact that they don't sell primatene mist or any other OTC inhalers. it makes me want to hold the people that are responsible under water for awhile so they can see the shea[Show More]i have used this product for a while for emergency's i found it worked pretty good. but it did make me a bit jumpy after. but so does the atomizer that they give you in the ER. which is where us asthma suffers end up due to the fact that they don't sell primatene mist or any other OTC inhalers. it makes me want to hold the people that are responsible under water for awhile so they can see the shear panic you get when you have a bad attack come on. then maybe they will see what it feels like when we have a attack. we really need to take a stand about things like this. whats next?? are they going to charge us to breath oh wait they are already doing it to us that have asthma.. it sucks! and even if you do have the proair script you can't get a extra to keep in your car just incase you happened to forget it and your miles away. what are we supposed to do then? ER? Die? i guess life was to easy for us then, when we could walk in to a drug store or sometimes a regular store and buy something that actually would SAVE YOUR LIFE!! its prejudice against people with asthma!

  • RobApril 13, 2016 at 11:11 pm

    I have used primetene since I was young, I am 51 now and the last 3 years have a hunt and search for something that works. Well you all dont want to hear my complaints about the fda, government or doctors who are quick to tell me I need a $300.00 inhaler that dont work or I dont have ashtma its copd....money grubbing, worthless people can stay pout of my life. Asthmanerfrin works great. atomizer i[Show More]I have used primetene since I was young, I am 51 now and the last 3 years have a hunt and search for something that works. Well you all dont want to hear my complaints about the fda, government or doctors who are quick to tell me I need a $300.00 inhaler that dont work or I dont have ashtma its copd....money grubbing, worthless people can stay pout of my life. Asthmanerfrin works great. atomizer is crap. here is a fool proof way to beat them. I buy the Asthmanerfrin and use it in my nebulizer I bought on ebay brand new for $45.00 no mess no fuss just easy symptom free night again.

  • GurpJanuary 9, 2016 at 7:40 am

    Shannon, yes. That does work. I also found that letting the cup dry for a very long time... as much as a month... will persuade it to work for a while. I eventually bought an Aura atomizer (rathrr expensive) but it works like a truck and is very un-finicky.

  • ShannonJanuary 5, 2016 at 5:28 pm

    I solved my atomizer issue by rinsing the head with distilled, putting the head in an ultrasonic cleaner (for eyeglasses, rings, etc.) filled with distilled water and run it on 2 cycles, then remove dry off and use a solution 1/3 vinigar - 2/3 distilled water in the head turning the unit off and on 4 or 5 times to flush the solution throughout the unit head. Since then I have not had a problem wi[Show More]I solved my atomizer issue by rinsing the head with distilled, putting the head in an ultrasonic cleaner (for eyeglasses, rings, etc.) filled with distilled water and run it on 2 cycles, then remove dry off and use a solution 1/3 vinigar - 2/3 distilled water in the head turning the unit off and on 4 or 5 times to flush the solution throughout the unit head. Since then I have not had a problem with my unit.

  • susanOctober 14, 2015 at 7:17 pm

    this POS atomizer is the worst......so are their customer service reps. I contacted them about a month ago to inquire about a new cap, since once again it's become clogged. I was told (like many others here) that replacement parts are no longer available.....but....if I send in the defective parts AND my receipt for purchase, I would receive a refund for purchase PLUS $5 to cover my shipping cos[Show More]this POS atomizer is the worst......so are their customer service reps. I contacted them about a month ago to inquire about a new cap, since once again it's become clogged. I was told (like many others here) that replacement parts are no longer available.....but....if I send in the defective parts AND my receipt for purchase, I would receive a refund for purchase PLUS $5 to cover my shipping costs. Well.......after a very frustrating phone call today, I was told that the receipt I sent (along with copies of ALL the refills purchased) is invalid because the date isn't visible on the receipt.....hell with the costs of all this sh*t I purchased $50 for the starter kit and 5 boxes of refills @ $25 each......now they don't want to stand behind their word!!!!!!!!!! So I told them to just send back my original atomizer, that I sent to them and I was told they can't do that either.....so now they have everything...my atomizer with broken cap AND their $$$$$$...that they promised me upon receipt of said items. These people need to be called out for the shoddy product and poor customer service. They stand behind absolutely nothing!!!!!!

  • WilliamSeptember 10, 2015 at 12:34 pm

    Junk junk junk! The atomizer! Medicine is great! Also been through many cups but called for another and they are discontinued! This needs to be brought to a huge lawsuits to all involves! They can't get away with this fraudulent scam!!!! This is assinine! Also big question!!? Will the e-cigs clog up using this medication? That's all I got!

  • Case IIIJuly 14, 2015 at 6:05 pm

    Could someone tell me how & what e-cigs will work using the vials? DAMN I miss my Primatine !!!!!

  • NancyJuly 14, 2015 at 2:28 am

    Doctors only care about money talks and BuLLsh*t walks statement so they never will care about their patients only that money because nowadays money is the biggest measure of society today. Doctors only care about the money but let a female doctor or male doctor have a child that has asthma and the child needs a fast acting inhaler and the doctor lives several miles away from the hospital and the [Show More]Doctors only care about money talks and BuLLsh*t walks statement so they never will care about their patients only that money because nowadays money is the biggest measure of society today. Doctors only care about the money but let a female doctor or male doctor have a child that has asthma and the child needs a fast acting inhaler and the doctor lives several miles away from the hospital and the child could die before the doctor gets the child there, but the little country grocery store which is a block away has Primatine Mist there. The doctor runs to the store buys one and gives it to the child then the doctor can see he or she has save their child by using it maybe they would change their mind but what the point how many doctors you know live 20 or 30 miles from a hospital and if the drug store was in the little country grocery store why not write a prescription for the kid real fast, because most doctors have to be on duty before they can write out a prescription even some state laws indicates this too. but you see my point let a doctor or the people from the FDA have a child at home with asthma and their inhaler from the doctor's office runs out and they do way before Primatine does, but the hospital is a long way to go to the child is losing air and slowly dying and the little store a block away has a Primatine Mist inhaler I bet they will bring it back if it saves their child regardless of the so called harmful effects to the OZONE if they have a child that has asthma they should think about they children's life if this scenario happen to them. Then they will see the point of bringing back the mist we all loved and it saved our lives without the pills that causes weight gain, and expensive prescriptions. So FDA people and Doctors what if this happen to you and you could save your child with a Primatine Mist inhaler would you put it back on the market then yes you probably would, so why not now before it is too late for your child and mine.

  • mikeJuly 2, 2015 at 10:28 am

    cleaning the atomizer with rubbing alchohol made it last 3 times as long as with the vinegar it recommends but even still thats alot of $$ to replace it every 3 months. i couldn't agree more, bring back primatine mist

  • ToniJune 26, 2015 at 10:57 am

    have to agree with everyone that the atomizer is apiece of junk! I've gone through at least 12 of them, and they are not reliable in an emergency! The medicine does work but what good is it if you can't use the atomizer. Something needs to be changed with it, or like everyone else said bring back primatene. Never had issues then. Close to $60 for a starter kit, and when you have to keep buying new[Show More]have to agree with everyone that the atomizer is apiece of junk! I've gone through at least 12 of them, and they are not reliable in an emergency! The medicine does work but what good is it if you can't use the atomizer. Something needs to be changed with it, or like everyone else said bring back primatene. Never had issues then. Close to $60 for a starter kit, and when you have to keep buying new ones it adds up

  • KenPJune 16, 2015 at 9:36 pm

    I got tired of replacing the cups, too. When the last one clogged up, even after religiously following the cleaning instructions, I tried something different. I filled the tiny orifice for the medication with some straight vinegar. Then I took a Q-tip and jammed it into the space and swabbed the back of the metal disk. Tight fit, but the cotton eventually conformed to the tight space and I was abl[Show More]I got tired of replacing the cups, too. When the last one clogged up, even after religiously following the cleaning instructions, I tried something different. I filled the tiny orifice for the medication with some straight vinegar. Then I took a Q-tip and jammed it into the space and swabbed the back of the metal disk. Tight fit, but the cotton eventually conformed to the tight space and I was able to get to the entire disk. I also took the vinegar-soaked end of the Q-tip and lightly swabbed the front of the disk, what the instructions call the "mesh" and cautions us not to touch. I then rinsed the cup thoroughly with tap water and soaked it in distilled water for a while. After a few hours of soaking, I repeated the vinegar swab and then mounted the cup on the base with the switch. I turned it on and off a few times and got a wisp of vapor. I then rinsed and soaked in distilled water for a few hours and repeated the process. The mist became stronger, over a couple more times, to the point it was useable but not as strong as new. Because of the long soaking times, I went ahead and bought another unit. It went kaput in a few days as expected but I put it through the above cleaning process and brought it back to life. I now have two functioning units one operating at this point for fifteen months and the other for eleven months. I only need to go through the vinegar treatment intermittently once the cup starts working just for maintenance, maybe once every four refills of the medication cup. Hope this works for others.

  • JackieJune 10, 2015 at 8:02 pm

    I purchased 4 of the Asthmanefrin medication cups and they all sucked. I also purchase 2 replacement medication cups and they sucked as well. They are nothing but pieces of crap. But what I did find was something that was made by a manufacture that is a hand held atomizer that turns the liquid into a fine mist and it works great.

  • LWCOUNTJune 9, 2015 at 5:35 am

    The EZ Breathe Atomizer recall was issued because a washer in the atomizer packaging could become dislodged during use, putting patients at risk of accidental choking or swallowing.--What the hell Does the FDA have down syndrome? Is this too complicated for these greed meisters? The damn thing stops working that should be in your damn report you ingrates. DO YOUR DAMN JOB assholes. Provide and [Show More]The EZ Breathe Atomizer recall was issued because a washer in the atomizer packaging could become dislodged during use, putting patients at risk of accidental choking or swallowing.--What the hell Does the FDA have down syndrome? Is this too complicated for these greed meisters? The damn thing stops working that should be in your damn report you ingrates. DO YOUR DAMN JOB assholes. Provide and oversee faulty products. You could misuse a toaster oven and burn the house down that's all that means.

  • KarenJune 5, 2015 at 4:16 am

    This decision is ruining my life!! Albuteral and Levalbuteral, both give me asthma and have WAY worse side effects. Look it up in any drug book. Please reconsider this decision. I have night-time asthma. I've used epinephrine to treat this for 42 years and I am healthy and my lungs are great. I had to stop using cortisone back in 1985 because of all the horrible side effect,s that gave me a [Show More]This decision is ruining my life!! Albuteral and Levalbuteral, both give me asthma and have WAY worse side effects. Look it up in any drug book. Please reconsider this decision. I have night-time asthma. I've used epinephrine to treat this for 42 years and I am healthy and my lungs are great. I had to stop using cortisone back in 1985 because of all the horrible side effect,s that gave me a horrible reaction after taking the cortisone for years. I can't take it at all now. Taking the Primatene pills make my heart race and I can't sleep which ruins my life. I'm on antidepressants. I can't take the pills. It is too dangerous.

  • Eljac99June 3, 2015 at 3:19 am

    I don't know that I believe that Jane's son went crazy from a asthma meds!! I would love to hear more!!

  • SueMay 10, 2015 at 2:01 am

    I too was a primatene user for many years, until they pulled it from the shelves. I thought for sure something that worked half as good would someday hit the shelves, asthmanefrin works well but I also had major problems with the atomizer. It works well and then all of a sudden it doesn't work at all. I have at least 10 atomizers that don't work. A lot of good they do when you are having an a[Show More]I too was a primatene user for many years, until they pulled it from the shelves. I thought for sure something that worked half as good would someday hit the shelves, asthmanefrin works well but I also had major problems with the atomizer. It works well and then all of a sudden it doesn't work at all. I have at least 10 atomizers that don't work. A lot of good they do when you are having an asthma attack. Now you can find the medicine in the stores but not the atomizers, so I ask what good is that? I guess I'll have to get an e cig to help me

  • GregMay 2, 2015 at 5:06 pm

    I used Primatine for 40 plus years with no problems ASTHMANEFRIN works fine for me but I too have atomizer troubles the doctor prescribed crap doesn't work where the hell is Primatine I use the Asthmanefrin and it works great except no life on the atomizer will disassemble one under microscope and see if I can find evidence of failure cause.Thanks and if anyone finds a replacement E-mail me at su[Show More]I used Primatine for 40 plus years with no problems ASTHMANEFRIN works fine for me but I too have atomizer troubles the doctor prescribed crap doesn't work where the hell is Primatine I use the Asthmanefrin and it works great except no life on the atomizer will disassemble one under microscope and see if I can find evidence of failure cause.Thanks and if anyone finds a replacement E-mail me at supertech007@live.com

  • JoeApril 30, 2015 at 7:08 am

    I finally filed a complaint with the FDA, but have never had a reply from them. The EZ Atomizer malfunctions. They replaced several times but never replied to my concerns as once the Atomizer created a mass of liquid I inhaled that burned my lungs for quite some time. I have all the correspondence, including their attempts to claim "user" caused the problem despite, a web search would show, and [Show More]I finally filed a complaint with the FDA, but have never had a reply from them. The EZ Atomizer malfunctions. They replaced several times but never replied to my concerns as once the Atomizer created a mass of liquid I inhaled that burned my lungs for quite some time. I have all the correspondence, including their attempts to claim "user" caused the problem despite, a web search would show, and still shoes, the problem(s) were not isolated to me. They will not communicate and have not since the complaint was filed by me with FDA.

  • EARLApril 28, 2015 at 1:26 pm

    I'M 81 YEARS OLD AND A PROFESSIONAL ENGINEER. I HAVE HAD ASTHMA SINCE I WAS A TEENAGER WORKING ON THE FARM. WHEN I FOUND PRIMATENE MIST I WAS SO HAPPY. I COULD GET IMMEDIATE RELIEF THAT ANYONE COULD AFFORD. AFTER THE PRIMATENE WAS BANNED I WENT TO MY DOCTOR AND WAS GIVEN A PRESCRIPTION FOR ALBUTEROL SULFATE. THIS COSTS ABOUT 3 TIMES AS MUCH AND IS ABOUT 50% AS EFFECTIVE. I WAS EXCITED TO FIND[Show More]I'M 81 YEARS OLD AND A PROFESSIONAL ENGINEER. I HAVE HAD ASTHMA SINCE I WAS A TEENAGER WORKING ON THE FARM. WHEN I FOUND PRIMATENE MIST I WAS SO HAPPY. I COULD GET IMMEDIATE RELIEF THAT ANYONE COULD AFFORD. AFTER THE PRIMATENE WAS BANNED I WENT TO MY DOCTOR AND WAS GIVEN A PRESCRIPTION FOR ALBUTEROL SULFATE. THIS COSTS ABOUT 3 TIMES AS MUCH AND IS ABOUT 50% AS EFFECTIVE. I WAS EXCITED TO FIND THE ASTHMANEFRIN AS IT GAVE ME IMMEDIATE RELIEF. I TOO HAD A PROBLEM WITH THE ATOMIZER. HOWEVER, THEY ALWAYS SENT ME A REPLACEMENT WHEN I CONTACTED THEM. FINALLY I REALIZED THAT SPRAYING THE VINEGAR SOLUTION THRU THE ATOMIZER AFTER SOAKING WAS THE ANSWER. AFTER THAT I HAD NO PROBLEMS. I FEEL WE HAVE BEEN SCAMED AGAIN BY OUR FDA. BIG BROTHER WILL TAKE CARE OF US AND OUR DOLLARS. LOOKING FOR ANOTHER TREATMENT AT THIS TIME.

  • MattApril 25, 2015 at 5:42 am

    I have severe allergy onset asthma that makes it so hard to breathe I almost pass out. I found asthmanefrin a few years ago and it has helped me tremendously. The atomizer has clogged a few times, but nothing some long soaks in the vinegar water solution and a few whacks to the cup didn't fix. Lately the atomizer has gotten really finicky and I began my search for a new atomizer. Surprise!! [Show More]I have severe allergy onset asthma that makes it so hard to breathe I almost pass out. I found asthmanefrin a few years ago and it has helped me tremendously. The atomizer has clogged a few times, but nothing some long soaks in the vinegar water solution and a few whacks to the cup didn't fix. Lately the atomizer has gotten really finicky and I began my search for a new atomizer. Surprise!! They don't make it anymore !! But they still sell the refills? I bet those will be gone soon too. For God's sake, why would they take away our breathing? What will I do when they stop producing refills?

  • CynthiaApril 19, 2015 at 9:44 pm

    Sorry to sound stupid, but where do you put the medicine if you are using an e-cig? I am not familiar with these e-cigs and have seen several different types. Do I need to buy a certain kind of e-cig? Thanks in advance for any help.....I think we should all send our old non-working contraptions to the FDA and see what is worse on the ozone..... numerous piles of useless plastic or a few empty b[Show More]Sorry to sound stupid, but where do you put the medicine if you are using an e-cig? I am not familiar with these e-cigs and have seen several different types. Do I need to buy a certain kind of e-cig? Thanks in advance for any help.....I think we should all send our old non-working contraptions to the FDA and see what is worse on the ozone..... numerous piles of useless plastic or a few empty bottles of primatene.

  • JackApril 17, 2015 at 11:45 pm

    The medicine cup is junk. clean it every day and still it works for a while then poof ! nothing and no matter what you do it will not work. A remake is in order. My ecig delivers it a whole lot better than that piece of crap.

  • JackieApril 13, 2015 at 7:29 pm

    I have had to purchase 6 different replacement medication cups. I just called these people about the Asthmanefrin and they replacement cups are no longer being made. What about the replacements people had to buy? The replacement cups suck. Asthmanefrin and EZ Breathe Atomizer Problems Result in FDA Warning - See more at: http://www.aboutlawsuits.com/asthmanefrin-ez-breathe-atomizer-problems-fd[Show More]I have had to purchase 6 different replacement medication cups. I just called these people about the Asthmanefrin and they replacement cups are no longer being made. What about the replacements people had to buy? The replacement cups suck. Asthmanefrin and EZ Breathe Atomizer Problems Result in FDA Warning - See more at: http://www.aboutlawsuits.com/asthmanefrin-ez-breathe-atomizer-problems-fda-warning-54316/#sthash.3aN9Hsfe.mDUscFUf.dpuf

  • wielApril 4, 2015 at 3:00 pm

    Primatene mist taken off the market because of CFC propellant, yet if you go to a doctor spend 5 times the price you get a prescriptions inhaler that contain HFC 134a as the propellant. This is the same thing that is in your car air conditioner. That you can read up on 134A at any auto part store this stuff can damage your lungs. 134A should never be inhaled. So tell me how much the FDA, politicia[Show More]Primatene mist taken off the market because of CFC propellant, yet if you go to a doctor spend 5 times the price you get a prescriptions inhaler that contain HFC 134a as the propellant. This is the same thing that is in your car air conditioner. That you can read up on 134A at any auto part store this stuff can damage your lungs. 134A should never be inhaled. So tell me how much the FDA, politicians and doctors really care and look out for us?? It not about ozone it about big prescription drug companies and doctors getting rich not your health. This government is out dated and should fall, the greed the 1% caused the fall of romans and spheroids this too will cause the fall of the USA. Primatene mist could have changed the gas to CO2 and that be safer then 134A.

  • TomMarch 30, 2015 at 7:13 pm

    Primatene mist saved my life when I was around 5 years old...I have used it up until the day it was pulled off the shelf. The replacement asthmanefrin works but the atomizer does not last..I literally own 12 of them at nearly $50 a piece..my hands were tied I needed it. There is nothing else that works..I have gone do doctors over the years and always ended up back with the Primatene mist..now I[Show More]Primatene mist saved my life when I was around 5 years old...I have used it up until the day it was pulled off the shelf. The replacement asthmanefrin works but the atomizer does not last..I literally own 12 of them at nearly $50 a piece..my hands were tied I needed it. There is nothing else that works..I have gone do doctors over the years and always ended up back with the Primatene mist..now I can't find the starter kit at any of the stores..only the refills..what's going on?? I hope the e cigarette thing works out because that's my only hope...

  • MaryMarch 21, 2015 at 3:18 am

    I have used an inhaler since the age of 9 years old.....Medihaler Epi, Primatene, Bronkaid, prescription inhalers which all had horrible side effects for me. After the FDA rushed to remove Primatene off the market and I wrote to the FDA......I stated using Asthmanefrin and it is soo good. The relief is instantaneous. I had a problem with the cup where the medicine goes only but the medicine was [Show More]I have used an inhaler since the age of 9 years old.....Medihaler Epi, Primatene, Bronkaid, prescription inhalers which all had horrible side effects for me. After the FDA rushed to remove Primatene off the market and I wrote to the FDA......I stated using Asthmanefrin and it is soo good. The relief is instantaneous. I had a problem with the cup where the medicine goes only but the medicine was well for me. I do not need any steroids which makes me gain weight.....although some doctors say is does not......bull crap to them, I know my body and I gain weight when I take that type of medicine. We need to petition the FDA to keep it hands off this medicine and I take responsibility for my own life.....this medicine has kept me out of the hospital because it works. I am not 66 years old and my pulmonary doctor is amazed that it works so well for me. We need to petition every doctor that wants to make money on our lives.......we should sue them for holding out on medicine that works for us. Any Lawyers out there want to start a "Class Action Law Suit against the FDA and Doctors who impede the progress of blocking - effective breathing medicines" for Asthma suffers. Anyone who wants to join me.....I am willing to go forth and get this medicine available for all of us. For those of you who cannot use the product, just have your doctor prescribe you a prescription. I have found a way to clean the cap by taking a paper towel to sock up any excess medicine left in the cap, taking tips of the paper towel by twisting it and using a little distilled water on the tip and slightly go in between each side a few times....it cleans the old built up meds (do it until it looks real clean) then I gently us the tip of the paper towel (by rolling it into a tip) and gently - gently rub the outside of the mess (you will see some of the medicine absorbed on the paper towel.....keep doing that until you see no more medicine.....the mess gets clogged because it accumulates behind the mess and clogs it up....if you keep the medicine from building up, the mess will not get clogged.......works well for me for......just a hint....let it dry well before reusing. Now that's my personal way of cleaning my caps....it may not work for everyone depending on how well or gently you clean the cap. I have been able to keep inhalers running for months......good luck !!

  • MikeMarch 11, 2015 at 1:06 am

    Like others here, lifelong asthma victim. Used Primetime mist successfully for almost 50 yrs. When my 'stockpile' of inhalers ran out, I discovered this product. OTC epi has allowed a return to 'normal' life. The EZbreath atomizer is truly not trustworthy, regardless of cleaning instructions. I picked the DeVilbiss 45 nebulizer for my delivery system. Bulky, but reliable. Will now try the E[Show More]Like others here, lifelong asthma victim. Used Primetime mist successfully for almost 50 yrs. When my 'stockpile' of inhalers ran out, I discovered this product. OTC epi has allowed a return to 'normal' life. The EZbreath atomizer is truly not trustworthy, regardless of cleaning instructions. I picked the DeVilbiss 45 nebulizer for my delivery system. Bulky, but reliable. Will now try the Ecig idea for the car. Thanks!

  • BillMarch 8, 2015 at 7:59 pm

    I've had the same problem with the atomizer. I have been able to get it to work in an emergency, by leaving it on for about 10 minutes, and then opening and shutting the cup forcefully. It seems like the membrane becomes less permeable. The cup is air tight because then the vapor diffuses from a high pressure to a low pressure area through the membrane. If you force the cup shut, and listen to the[Show More]I've had the same problem with the atomizer. I have been able to get it to work in an emergency, by leaving it on for about 10 minutes, and then opening and shutting the cup forcefully. It seems like the membrane becomes less permeable. The cup is air tight because then the vapor diffuses from a high pressure to a low pressure area through the membrane. If you force the cup shut, and listen to the air rush out, it seems to begin to push some vapor through the membrane. If I hold a light to the cup, I can begin to see some vapor welling up behind the membrane. Then eventually after a few more minutes, pushing the power button off and then back on a few seconds later, will send a wisp of vapor through the membrane. Then I might have to repeat the process a few more times, but eventually there will be a small but steady plume of vapor emerging from the cup. A few breathes is enough to get some relief. This is no fun at 4 in the morning when you're gasping for air, but at least it works in an emergency. I think I'm going to try the ecig idea.

  • ericMarch 7, 2015 at 7:08 pm

    Yes, the delivery system is junk. I had the opportunity to speak with Nephron's former Chief Science officer a couple times last year and he told me the device was defective and they knew it. He said the company was trying to change the design and manufacture it here in the US and then suddenly after that he "resigned" from his position. From what I can gather now, the company has no intention to [Show More]Yes, the delivery system is junk. I had the opportunity to speak with Nephron's former Chief Science officer a couple times last year and he told me the device was defective and they knew it. He said the company was trying to change the design and manufacture it here in the US and then suddenly after that he "resigned" from his position. From what I can gather now, the company has no intention to make a new delivery model, sold off all their inventory, and inventory of the refills may not be replenished once they're gone... they're just going to go away quietly, just like the way we saw Primatine disappear. My guess is the pressure from the pharmaceuticals is too costly to fight. I use the refills in my home nebulizer just fine. I have enough stocked up to last through June of 2016 as that's the most current expiration date I can find available. Just my 2 cents worth...

  • PaulFebruary 21, 2015 at 8:33 pm

    I agree, the delivery system is total garbage. You should be able to purchase just the atomizer. A Big thanks to JOhnny on the suggestion of using an e-cig as a delivery system.

  • MarthaFebruary 15, 2015 at 10:58 am

    Not only device not work but now you pay twice the price if you can find replacements for previous devices. So nephron advertised a device and medication to replace Primatine. They have the medication but no effective was to distribute the medications? Why are they not being sued for false advertisement and misleading former Primatine users? Nephron should be sued! Every person using the device h[Show More]Not only device not work but now you pay twice the price if you can find replacements for previous devices. So nephron advertised a device and medication to replace Primatine. They have the medication but no effective was to distribute the medications? Why are they not being sued for false advertisement and misleading former Primatine users? Nephron should be sued! Every person using the device has been scammed!

  • LutherFebruary 4, 2015 at 12:20 am

    I agree with these posts. I have probably bout 15 - 20 of the starter kits by now because the atomizer is JUNK! They do not last no matter how many times you wash these things out! I used Primatene mist from the time I was 12 years old until they took it off the market for the bogus ozone excuse! I'm now 59 years old and have NEVER had a problem with it - ever. I have had nothing BUT problems with[Show More]I agree with these posts. I have probably bout 15 - 20 of the starter kits by now because the atomizer is JUNK! They do not last no matter how many times you wash these things out! I used Primatene mist from the time I was 12 years old until they took it off the market for the bogus ozone excuse! I'm now 59 years old and have NEVER had a problem with it - ever. I have had nothing BUT problems with Asthmanefrin atomizers. First off, you CANNOT put the thing in your pocket so I have to carry around this little bag and keep it in my computer case. I complained on the Asthmanefrin website about the atomizers and they got back to me right away via phone - I mean within 2 hours of my leaving a comment. They exchanged all of the atomizers I'd collected up to that point, and replaced every one of them and you know what? Those replacements all went bad too! I just got back from making yet ANOTHER trip to CVS and then to Walgreens - they aren't carrying the atomizers any more??? I mean, there isn't even a place on the shelf where they would go any more! So, now what do I use??? The odd thing about it, both CVS and Walgreens still carry the refills - which are useless without the atomizers.... Someone PLEASE BRING BACK Primatene Mist and let me get on with my life!

  • LeelaJanuary 10, 2015 at 7:40 pm

    I too was a Primatine user. I was shocked they took it off the market and used the ozone as an excuse. It doesn't take much insight as to why it was discontinued. Doctors and the pharmaceutical companies made a whole lot more from prescriptions such a Symbacort and Dulera. I have used both of those and have had severe side effects. I was happy to see finally there was an alternative again. Asthma[Show More]I too was a Primatine user. I was shocked they took it off the market and used the ozone as an excuse. It doesn't take much insight as to why it was discontinued. Doctors and the pharmaceutical companies made a whole lot more from prescriptions such a Symbacort and Dulera. I have used both of those and have had severe side effects. I was happy to see finally there was an alternative again. Asthmanefrin is very effective as a vapor, but must be used cautiously, no more than 3 inhalations at a time. It also doesn't burn like the prescription meds did. I am however having an issue with the atomizer. I am I month in and the atomizer does not work as well. Less vapor. I now clean it and let it air dry after each use. That seems to help. Also using distilled water is probably better than tap water as instructed. I will stick with it because I feel better using something not so toxic. Easy solution, bring back Primatene.

  • CandyJanuary 7, 2015 at 4:17 am

    I also agree with the comments here. The medication works great. I have never had any adverse side affects from it. The machime however is a whole other story. The thing is a piece of crap. I am very tired of replacing it, i intend to find an altwrnative.

  • C.SMITHDecember 9, 2014 at 6:46 pm

    BRING BACK OUR PRIMATENE MIST! How can we make this happen? I have lived with asthma my entire life (57 yrs) and Primatene was the only inhaler that actually worked for me. When they took it off the market I thought I would die - literally. Now, they are going to try to take the only alternative off of the market. The drug companies will not be happy until they kill us. Every single day of m[Show More]BRING BACK OUR PRIMATENE MIST! How can we make this happen? I have lived with asthma my entire life (57 yrs) and Primatene was the only inhaler that actually worked for me. When they took it off the market I thought I would die - literally. Now, they are going to try to take the only alternative off of the market. The drug companies will not be happy until they kill us. Every single day of my life I now think "God, I miss my Primatene". How can we get it back?

  • MaryDecember 2, 2014 at 5:26 am

    Works fine for maybe 3 weeks after that it sucks! For people who have a problem breathing this is supposed to be helpful but it's even worse when you need it & it do want work!! I have had it replaced 7 times & still shitty. Fix it or better yet put primetime inhaler back on the market!!! Or there shall be a lawsuit filed!

  • ArtNovember 22, 2014 at 6:04 pm

    As others have attested to here, my experience with the device has been a nightmare. Nephron has responded to complaints so far by adding a warning inside the packaging that states: " Warning: If no visible mist is emitted from device, seek other treatment". Good advice, but highly impractical at 2 am when gasping for air and believing I have already purchased a dependable medical device, which[Show More]As others have attested to here, my experience with the device has been a nightmare. Nephron has responded to complaints so far by adding a warning inside the packaging that states: " Warning: If no visible mist is emitted from device, seek other treatment". Good advice, but highly impractical at 2 am when gasping for air and believing I have already purchased a dependable medical device, which as it turns out...isn't. The medication is wonderful. The atomizer is the problem which Nephron has so far refused to address seriously. I wonder if any deaths have occurred because of inopportune timing of product failure? If so, I'm also wondering how many are considered as "acceptable loss" ?

  • Many times over.November 16, 2014 at 5:40 pm

    I've been using this for about a year or two. Unable to afford insurance and since Primatine was removed I was glad to see something in its place. I have however also had issues with the cup. I will admit the th have been great when I have to call in and report the issue. I have 3 on hand at a time I bought them so that when I have to return them I always have a back up. The medicine works very [Show More]I've been using this for about a year or two. Unable to afford insurance and since Primatine was removed I was glad to see something in its place. I have however also had issues with the cup. I will admit the th have been great when I have to call in and report the issue. I have 3 on hand at a time I bought them so that when I have to return them I always have a back up. The medicine works very well for me and after much research of the other drugs offered I'm not so sure I'm willing to risk those side effects, although when you can't get, a breath other side effects are the last thing your thing about. In short Pretty medicine, not so good dispenser. I'm assuming that the medicine purchases are what allows them to be able to continually rest u entry them. Although I'm thinking they are refurbished and sent back out. Until I can do something else I'm hanging with em. Just wished I didn't feel like a beggar having to call in so often to get replacements. The staff are great and get my new ones oUT ASAP. So thank y'all for that. And yes Primatine was caught in the cross fire of political B.S.

  • DavidNovember 16, 2014 at 8:24 am

    I've also been through a few of these devices. Works great for a week or so but that's about it. Complete garbage. Went to the manufacturers website and it isn't working either. Figures. Not being able to breathe at 2am sucks and finding out your breather crapped out you is frustrating. Especially when they're $50 a pop and the store is a 20 minute drive. F*** this company for putting out such a h[Show More]I've also been through a few of these devices. Works great for a week or so but that's about it. Complete garbage. Went to the manufacturers website and it isn't working either. Figures. Not being able to breathe at 2am sucks and finding out your breather crapped out you is frustrating. Especially when they're $50 a pop and the store is a 20 minute drive. F*** this company for putting out such a horrible product. I haven't tried the e-cigarette idea.

  • keithNovember 4, 2014 at 10:09 pm

    i have to agree that the machine sucks and the medicine works great but when you wake up and cant breath, i dont have asma but i do have emphazema and copd and i used primatine mist for years also and boy did it work and when the feds took it of the market i was pissed, jack asses they should put a pillow over there faces for a day. i usually let mine soak in very hot water for awhile. the cig ma[Show More]i have to agree that the machine sucks and the medicine works great but when you wake up and cant breath, i dont have asma but i do have emphazema and copd and i used primatine mist for years also and boy did it work and when the feds took it of the market i was pissed, jack asses they should put a pillow over there faces for a day. i usually let mine soak in very hot water for awhile. the cig machine also cost so....

  • KellyOctober 20, 2014 at 11:28 pm

    This is the 2nd atomizer I've bought just this year. I don't have any health insurance anymore due to the monthly premiums going up so high, I couldn't afford it anymore. I also had to stop using the prescription inhalers because they were outrageously expensive. They were both close to 300 dollars a piece. So, I find this Asthmanefrin and it works great but the atomizer will only work for a short[Show More]This is the 2nd atomizer I've bought just this year. I don't have any health insurance anymore due to the monthly premiums going up so high, I couldn't afford it anymore. I also had to stop using the prescription inhalers because they were outrageously expensive. They were both close to 300 dollars a piece. So, I find this Asthmanefrin and it works great but the atomizer will only work for a short period of time, even when you clean and store per manufacture instructions. Now, I see someone says using an E-cigarette delivers the medication great, guess I'll be buying one in the next few minutes! I used Primate Mist for years and it worked great. They yanked it off the market which was really unfair to us Asthmatics! When you can't breathe you don't need to be wasting time messing around with an atomizer that just half works or doesn't work at all!

  • Wheezy JonSeptember 2, 2014 at 5:00 am

    It's true, the delivery system is poorly designed and does not last. But the idea of using the solution IN AN ELECTRONIC CIGARETTE WORKS BEAUTIFULLY! Say it out loud for everyone with asthma to hear! I'd we all stop buying the garbage atomizer and start using easily available ecigs, bet you a dollar that they fix the delivery system post haste. E CIGARETTES WORK TO DELIVER ASMANEFERIN!

  • owenSeptember 1, 2014 at 6:52 pm

    It is virtually impossible to keep the mesh clear in the medicine cup. I recommend post a video to see how the experts do it.

  • JaypAugust 16, 2014 at 2:13 am

    I have to agree with others whom wrote their experiance with this device, it is a piece of crap, even with the maintenance as suggested by manufacturer atomizer still stops working; its a sad day when the feds would take primatine mist off the shelves( which worked) only to be replaced by this thing. This company is messing with peoples lives. Asthma, copd is not something you mess with, this[Show More]I have to agree with others whom wrote their experiance with this device, it is a piece of crap, even with the maintenance as suggested by manufacturer atomizer still stops working; its a sad day when the feds would take primatine mist off the shelves( which worked) only to be replaced by this thing. This company is messing with peoples lives. Asthma, copd is not something you mess with, this product is so unreliable. The pharmaceautical conpany should be sued for negeliance

  • JOhnnyJuly 26, 2014 at 5:54 pm

    I've had no problems with it as it works perfect for me, however - I found it is better to use this medication in an electronic cigarette to inhale the medication' it works better than the atomizer does. I agree' the U.S. Government and the AMA shafted asthma suffers by removing Primatene Mist from the market. I hope they burn in hell for every child that suffers or dies as a result of their acti[Show More]I've had no problems with it as it works perfect for me, however - I found it is better to use this medication in an electronic cigarette to inhale the medication' it works better than the atomizer does. I agree' the U.S. Government and the AMA shafted asthma suffers by removing Primatene Mist from the market. I hope they burn in hell for every child that suffers or dies as a result of their actions.

  • KevinJuly 12, 2014 at 4:58 am

    Sign me up... I used primatene for over 30 years and it was always available in an an emergency without finding $60 dollars in an emergency....

  • YukariJuly 11, 2014 at 6:44 pm

    Drug works great, device sucks not reliable. We have purchased 6 or 7 starter kit between my roommate and I since it's been out on the market. Problem is the mesh inside the cup, why can't we buy just cup by itself? I have all the heating device working and one cup.

  • not herMay 23, 2014 at 1:31 pm

    DO NOT BUY this crap!!! Go to a doctor and get a prescription for real medicine !!

  • SteveMarch 16, 2014 at 8:16 pm

    The medication works great but the delivery system is total junk. It clogs even with regular cleaning and is not reliable for emergencies. The FDA needs to stop being evil A-holes and let primatene mist come back to market..

  • JaneJanuary 14, 2014 at 12:12 pm

    That crap is awful my son was sent to a mental institution because it made him paranoid . He quit his good paying job because "they were out to get him". His blood pressure was elevated to heart attack level! he was getting rapid fever onset. Then miraculously the fever woul go away then return. Then he was getting the shakes like he has a sever case of Parkensons. He kept hearing sirens in his h[Show More]That crap is awful my son was sent to a mental institution because it made him paranoid . He quit his good paying job because "they were out to get him". His blood pressure was elevated to heart attack level! he was getting rapid fever onset. Then miraculously the fever woul go away then return. Then he was getting the shakes like he has a sever case of Parkensons. He kept hearing sirens in his head . I think he still believes that the co he worked for is out to get him. If you are using the crap please stop! My son still does not realize all the side effects and he may never fully recover.

  • MikeJanuary 2, 2014 at 3:35 pm

    The bottom line is that prescription drug companies and doctors with profit motives are behind this war against OTC asthma medications. They want to get everyone with asthma on prescription inhalers so they can add more money to their own pockets in the form of prescriptions and doctor's office visits. The prescription drug companies who make asthma inhalers spent millions of dollars lobbying cong[Show More]The bottom line is that prescription drug companies and doctors with profit motives are behind this war against OTC asthma medications. They want to get everyone with asthma on prescription inhalers so they can add more money to their own pockets in the form of prescriptions and doctor's office visits. The prescription drug companies who make asthma inhalers spent millions of dollars lobbying congress to get Primatine Mist taken off the market. The whole thing about it destroying the ozone layer was a farce. The amount of CFC's that OTC asthma inhalers put into the air was completely insignificant compared to the amount put into the air by commercial industry. Banning CFC based inhalers didn't even make a dent in stopping the destruction of ozone. And I say that as an environmentalist myself. Profit motives of drug companies and doctors are behind getting OTC asthma inhalers taken off the market. Not concern for the environment. If you really want to sue someone, sue the federal government for taking Primatine Mist off the market under false pretenses that it was harming the ozone layer.

  • ChristopherDecember 10, 2013 at 6:43 pm

    I'm with Pat , this atomizer is a piece of garbage . Used the first one for about 2 weeks ,tried to clean as per instructions . Medication spurted out twice and then nothing . Called manufacturer ,told me to return non-working one and they would send me a complete new one .Received the new one ,and used for about 1 month ,cleaning occasionally ,then once again nothing . FDA should remove this stup[Show More]I'm with Pat , this atomizer is a piece of garbage . Used the first one for about 2 weeks ,tried to clean as per instructions . Medication spurted out twice and then nothing . Called manufacturer ,told me to return non-working one and they would send me a complete new one .Received the new one ,and used for about 1 month ,cleaning occasionally ,then once again nothing . FDA should remove this stupid piece of crap from the shelves and bring back Primatene Mist . The only reason the remove Primatene was that doctors used the ozone as an excuse ,so the could write more big $$$ prescriptions . Asthma is to spontaneous to be screwing around with this crap system .

  • PatDecember 9, 2013 at 1:32 pm

    I have had no side effects of the Asthmanefrin however, the system it self SUCKS !!! (pardon the language). After cleaning as instructed, the mist HARDLY come out and the clip the holds the lid close will not stay SHUT !! Needless to day I went and purchased a second on ( which my insurance will not cover) and it is doing the same thing!!! With having Asthma all my life it sure was nice to have[Show More]I have had no side effects of the Asthmanefrin however, the system it self SUCKS !!! (pardon the language). After cleaning as instructed, the mist HARDLY come out and the clip the holds the lid close will not stay SHUT !! Needless to day I went and purchased a second on ( which my insurance will not cover) and it is doing the same thing!!! With having Asthma all my life it sure was nice to have the Primatine Mist that you could just pump and go. I have had the doctor prescribe me the inhaler in the past but they didn't last as long and found that Primatine over the counter worked just as good or better. MAY I SUGGEST THE FDA RETURN THE PRIMATINE AND DON NOT BUY THE ASTHMANEFIN PRODUCTS !!!!

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