Reducing Reliance on Nexium, Prilosec, Similar Drugs Not Only Saves Money, But Study Indicates It Will Do No Harm
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Heartburn Drugs Like Nexium, Prilosec May Increase Risk of Serious Childhood Infections: Study Researchers found that serious childhood infection risks were even higher for those children who had taken PPIs both before, and during, the study. August 17, 2023 Irvin Jackson Add Your Comments A new study raises serious concerns about the use of a popular class of heartburn drugs among children, including widely known brand names like Nexium, Prilosec, Prevacid and others, indicating that the medications may increase the risk of digestive tract, ear, nose and throat, respiratory, and kidney infections. Known as proton pump inhibitors (PPI), the class of medications are designed to reduce the amount of acid in the stomach, treating gastroesophageal reflux disease (GERD), as well as heartburn, ulcers in the stomach and small intestines, and inflammation of the esophagus. In addition to Nexium, Prilosec and Prevacid, the class also includes the brand name medications Protonix, Zegerid, AcipHex, Dexilant and Vimovo, as well as a number of generic equivalents. In findings published this month in the medical journal JAMA Pediatrics, French researchers indicate that doctors should avoid prescribing children PPI medications, unless there is a clear indication of their need. Childhood PPI Infection Risks The nationwide cohort study involved data on more than 1.2 million children born between January 1, 2010, and December 31, 2018, including more than 650,000 of whom were given either PPIs or other types of heartburn drugs for the treatment of gastroesophageal reflux disease and other gastric acid-related disorders. Researchers followed up with the children for serious infections or other adverse events until December 31, 2019. According to the findings, exposure to drugs like Nexium and Prilosec were linked to a 34% increased risk of serious infections overall. This included a more than 50% increased risk of serious digestive tract infections; a 47% increased risk of ear, nose, and throat infections; a 30% increased risk of nervous system infections; and about a 20% increased risk in both lower respiratory tract infections, as well as kidney and urinary tract infections. The researchers found that the risks were increased for both bacterial and viral forms of infection. During the study, about 152,055 children who were given PPIs were diagnosed with a new, serious infection, at a rate of about 2.99 per 100 person-ears. In addition, those children who had been previously exposed to Nexium, Prevacid and similar drugs in the past seemed to have a slightly higher risk of infections than those taking them for the first time. “To our knowledge, this is the first study investigating the risk of serious infections associated with PPI use in young children for various sites and pathogens. Our results showed increased risks of serious infections overall but also risk of infections in the digestive tract, ENT sphere, lower respiratory tract, kidneys or urinary tract, and nervous system infections and both bacterial and viral infections,” the researchers concluded. “Proton pump inhibitors should not be used without a clear indication in this population.” August 2023 Nexium, Prilosec Lawsuit Update Although PPIs have been promoted for years as safe and effective, leading many to believe the heartburn drugs carry few serious side effects, manufacturers have faced thousands of Nexium lawsuits, Protonix lawsuits, Prilosec lawsuits and Prevacid lawsuits filed in recent years, each raising similar claims that plaintiffs were left with acute kidney injury, chronic kidney disease, end-stage renal failure and other unexpected health problems. Do You Know about… SPORTS BETTING ADDICTION LAWSUITS FOR YOUNG ADULTS Gambling addiction and severe financial losses have been linked to popular sports betting platforms like DraftKings, FanDuel, and Caesars. Lawsuits are being filed by young adults and students who were targeted by deceptive promotions, addictive app features, and aggressive marketing tactics. See if you qualify for a sports betting addiction lawsuit. Learn More SEE IF YOU QUALIFY FOR COMPENSATION Do You Know About… SPORTS BETTING ADDICTION LAWSUITS FOR YOUNG ADULTS Gambling addiction and severe financial losses have been linked to popular sports betting platforms like DraftKings, FanDuel, and Caesars. Lawsuits are being filed by young adults and students who were targeted by deceptive promotions, addictive app features, and aggressive marketing tactics. See if you qualify for a sports betting addiction lawsuit. Learn More SEE IF YOU QUALIFY FOR COMPENSATION Given common questions of fact and law raised in thousands of complaints brought throughout the federal court system, the litigation has been centralized before U.S. District Judge Claire C. Cecchi in New Jersey since late 2019, as part of an MDL or multi-district litigation. Following coordinated discovery into common issues that impact all of the cases, Judge Cecchi established a “bellwether” program where a small group of lawsuits that are representative of issues raised throughout the claims have gone through case-specific discovery and been prepared for a series of early trial dates. If a settlement is not reached before October 10, the first Nexium kidney damage bellwether trial will be held. The results, while non-binding on other cases, are expected to help the parties gauge how juries may respond to certain evidence and testimony that will be repeated throughout the litigation. However, following subsequent trials later this year and next, if the parties still have not made progress settling claims, Judge Cecchi may start remanding individual cases back to U.S. District Courts nationwide for individual trials. Written by: Irvin Jackson Senior Legal Journalist & Contributing Editor Irvin Jackson is a senior investigative reporter at AboutLawsuits.com with more than 30 years of experience covering mass tort litigation, environmental policy, and consumer safety. He previously served as Associate Editor at Inside the EPA and contributes original reporting on product liability lawsuits, regulatory failures, and nationwide litigation trends. Tags: Heartburn Drugs, Infections, Nexium, Prevacid, Prilosec, Proton Pump Inhibitors, Respiratory More Proton Pump Inhibitor Lawsuit Stories Reducing Reliance on Nexium, Prilosec, Similar Drugs Not Only Saves Money, But Study Indicates It Will Do No Harm April 15, 2024 Nexium, Prilosec Settlement Reached To Resolve Kidney Damage Lawsuits Against AstraZeneca October 4, 2023 Dementia Risk Linked to Nexium, Prilosec, Similar Heartburn Drugs After Long-Term Use: Study August 11, 2023 0 Comments PhoneThis field is for validation purposes and should be left unchanged.Share Your CommentsFirst Name*Last NameEmail* Shared Comments*This field is hidden when viewing the formI authorize the above comments be posted on this page Yes No Post Comment I authorize the above comments be posted on this page Weekly Digest Opt-In Yes, send me a weekly email with the latest lawsuits, recalls and warnings. Want your comments reviewed by a lawyer?To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.Contact Phone #Alt Phone #Private CommentsNOTE: Providing information for review by an attorney does not form an attorney-client relationship.CAPTCHAGA SourceGA CampaignGA MediumGA ContentGA Term Δ MORE TOP STORIES Dupixent Sales Surge Amid Growing CTCL Cancer Lawsuit Allegations (Posted: yesterday) Sanofi indicates Dupixent sales are growing stronger as the medication gathers more indications for use worldwide, despite recent cancer concerns. 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Reducing Reliance on Nexium, Prilosec, Similar Drugs Not Only Saves Money, But Study Indicates It Will Do No Harm April 15, 2024
Nexium, Prilosec Settlement Reached To Resolve Kidney Damage Lawsuits Against AstraZeneca October 4, 2023
Dementia Risk Linked to Nexium, Prilosec, Similar Heartburn Drugs After Long-Term Use: Study August 11, 2023
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