Seroquel Lawsuits

Seroquel-Lawsuits

Seroquel Lawsuit Overview

Seroquel litigation centered on allegations that AstraZeneca failed to warn patients and healthcare providers about serious metabolic side effects associated with its blockbuster antipsychotic drug.

Originally approved to treat schizophrenia and bipolar disorder, Seroquel was later prescribed to millions of adults and children for off-label uses such as insomnia and anxiety. Over time, mounting evidence linked the medication to rapid weight gain, hyperglycemia, and type 2 diabetes, leading to widespread concern among regulators and medical professionals.

As adverse event reports and internal company documents surfaced, lawsuits were filed nationwide claiming AstraZeneca had concealed data showing that Seroquel could cause dangerous blood sugar spikes and other health complications. These cases were centralized in multidistrict litigation (MDL No. 1769) in the U.S. District Court for the Middle District of Florida, allowing coordinated discovery and pretrial proceedings.

Facing thousands of claims, AstraZeneca ultimately agreed to settlements resolving most of the lawsuits, paying roughly $600 million to more than 28,000 plaintiffs. The litigation became one of the largest pharmaceutical mass torts of its time, drawing attention to the marketing of atypical antipsychotics and their underreported risks of diabetes and metabolic disorders.


Seroquel Litigation Updates

February 26, 2008: Court Denies AstraZenecaโ€™s Motion to Seal Seroquel Documents

A federal judge rejected AstraZenecaโ€™s attempt to seal internal company documents related to Seroquel, ruling that the public had a right to access evidence concerning the drugโ€™s safety and marketing practices. The decision allowed previously confidential materials to become part of the public record, increasing scrutiny of the antipsychoticโ€™s link to diabetes.

April 14, 2008: Seroquel Litigation: 8,787 Lawsuits Filed Against AstraZeneca

By spring 2008, court filings revealed that nearly 8,800 product liability lawsuits had been filed against AstraZeneca over Seroquel side effects. Plaintiffs alleged that the company failed to warn about risks of weight gain and diabetes, while aggressively promoting the drug for off-label uses. The volume of claims underscored the scale of the litigation before the first trials even began.

June 4, 2008: Seroquel Problems Mount as First Trial Approaches

As the first Seroquel lawsuit neared trial, reports surfaced of thousands of claims alleging the drug caused users to develop diabetes and weight gain. Plaintiffs accused AstraZeneca of concealing risks and aggressively promoting the medication for unapproved uses, setting the stage for one of the largest pharmaceutical litigations of the decade.

June 10, 2009: Seroquel Diabetes Suit to Begin June 29

The first federal bellwether trial for Seroquel lawsuits was scheduled to begin at the end of June. The case was expected to test whether AstraZeneca could be held liable for failing to warn about diabetes risks associated with its blockbuster antipsychotic. Both sides prepared to present years of medical data and company research before the jury.

October 16, 2009: Seroquel Lawsuit Uncovers Efforts to Promote Drug for Off-Label Use

Discovery in ongoing litigation revealed AstraZenecaโ€™s internal communications indicating plans to market Seroquel for unapproved psychiatric conditions. Plaintiffs alleged that the companyโ€™s off-label promotion led to widespread prescribing among patients who were not adequately warned about metabolic side effects. The revelations fueled public criticism and regulatory interest.

November 16, 2009: Delaware Judge Dismisses Seroquel Lawsuit

A Delaware state judge dismissed one of the Seroquel lawsuits, ruling that the plaintiff failed to establish causation between the medication and the alleged diabetes injury. The decision represented an early legal victory for AstraZeneca, though thousands of similar claims remained active in both state and federal courts.

June 17, 2010: AstraZeneca Seroquel Defense Costs Exceed $593 Million

Financial disclosures showed that AstraZeneca had spent nearly $600 million defending Seroquel-related litigation, including attorney fees and settlements. The mounting costs highlighted the scale of the legal battle as the company continued to deny wrongdoing and defend its marketing practices.

December 4, 2010: Generic Seroquel Blocked by U.S. Appeals Court

A federal appeals court upheld AstraZenecaโ€™s patent rights, delaying the release of generic versions of Seroquel. The ruling preserved the companyโ€™s market exclusivity and revenue stream amid ongoing legal and regulatory pressures tied to the drugโ€™s safety record.

April 27, 2010: Seroquel Settlement Reached with Federal Prosecutors

AstraZeneca agreed to pay $520 million to settle federal charges that it illegally promoted Seroquel for unapproved uses. The U.S. Department of Justice accused the company of misleading physicians about safety data and marketing the drug for conditions outside FDA approval. The settlement resolved one of the largest off-label marketing cases in history.

June 7, 2010: Seroquel Settlement Talks Ordered

The federal court overseeing Seroquel multidistrict litigation ordered both parties to enter mediation. The move was intended to explore potential global settlement options and reduce the massive backlog of individual diabetes injury claims. Negotiations began as trial preparations continued in parallel.

October 27, 2010: Two Seroquel Lawsuits in Delaware Dismissed

A Delaware judge dismissed two additional lawsuits, citing insufficient evidence that the drug directly caused plaintiffsโ€™ diabetes. The rulings followed a trend of mixed outcomes in state and federal cases, reflecting challenges plaintiffs faced in proving causation.

Company filings revealed that AstraZenecaโ€™s cumulative Seroquel litigation expenses continued to climb, even as some settlements were reached. Analysts noted that the ongoing legal costs were eroding profits and casting uncertainty over future liability exposure.

May 24, 2011: Seroquel Diabetes Trial Under Way

One of the remaining bellwether trials began in federal court, where plaintiffs argued that AstraZeneca ignored early warning signs linking Seroquel to diabetes. The case tested whether jurors would accept internal company documents as evidence of negligence in risk communication.

July 13, 2011: AstraZeneca Wins First Seroquel Diabetes Lawsuit at Trial

A jury sided with AstraZeneca in the first diabetes-related Seroquel trial, finding that the company had adequately warned prescribers about potential side effects. The verdict represented a key defense win that influenced future settlement negotiations across the MDL.

October 22, 2011: Dismissal of Seroquel Diabetes Lawsuit Upheld on Appeal

A federal appeals court affirmed the dismissal of a Seroquel diabetes claim, reinforcing the defenseโ€™s argument that plaintiffs could not conclusively prove causation. The decision further limited the scope of viable pending lawsuits nationwide.

April 27, 2010: Settlement Over Seroquel Marketing Reached with U.S. Department of Justice

AstraZeneca formally finalized its $520 million agreement with federal prosecutors, resolving allegations that the company misled doctors and marketed Seroquel off-label for conditions like dementia and anxiety. The settlement also required compliance monitoring to prevent future violations.

May 5, 2011: Remand of Seroquel Lawsuits Requested

Plaintiffsโ€™ attorneys asked the MDL panel to remand certain resolved or inactive Seroquel cases back to their home districts. The request aimed to expedite dismissals and settlements while preserving judicial resources. The motion came amid growing signs that the litigation was entering its final stages.

October 21, 2011: Thousands of Seroquel Lawsuits Should Be Remanded, Plaintiffs Argue

Lawyers representing plaintiffs urged the MDL judge to remand more than 10,000 remaining Seroquel cases to local courts for trial or closure. They contended that coordinated pretrial proceedings had been completed and centralized oversight was no longer necessary.

March 18, 2010: Settlement for Seroquel Lawsuits Reached in Some Cases

Reports indicated that AstraZeneca had reached partial settlements in certain Seroquel diabetes claims. The agreements covered plaintiffs with the strongest medical evidence of injury, suggesting that the company sought to limit exposure while continuing to contest weaker cases.

April 8, 2010: Seroquel Settlements Reached in Diabetes Lawsuits

Further progress was made toward resolution when AstraZeneca agreed to additional confidential settlements involving plaintiffs who developed diabetes after taking Seroquel. The developments suggested a broader settlement framework was taking shape behind the scenes.

September 29, 2010: 17,500 Seroquel Lawsuits Settled

AstraZeneca announced that it had resolved approximately 17,500 Seroquel claims through settlements totaling nearly $700 million. The resolution represented a major step toward ending the decade-long litigation and reducing pending caseloads in federal and state courts.

November 5, 2010: Seroquel Remand Vacated by Appeals Court

A federal appellate court vacated an earlier remand order in the Seroquel MDL, finding procedural errors in how certain cases were transferred back to state courts. The ruling temporarily slowed the final stages of litigation but did not affect ongoing settlement discussions.

July 29, 2011: AstraZeneca Reaches $68.5 Million Seroquel Settlement with States

AstraZeneca agreed to pay $68.5 million to resolve claims by 38 state attorneys general alleging deceptive marketing of Seroquel. The settlement closed out years of investigation into the companyโ€™s promotional tactics and required future compliance measures.

February 23, 2012: Nearly All Seroquel Lawsuits Settled Nationwide

By early 2012, AstraZeneca had resolved nearly all remaining Seroquel lawsuits through settlements, dismissals, or trial outcomes. The conclusion of the litigation ended one of the largest pharmaceutical mass torts of the 2000s, following billions in combined legal costs and penalties.


Seroquel Research and Reports

July 14, 2008: Zyprexa and Seroquel Side Effects Linked to Heart Disease

Medical researchers reported that users of antipsychotic medications like Seroquel and Zyprexa faced a higher risk of heart disease and sudden cardiac death. The findings raised renewed concerns about metabolic side effects such as obesity and elevated blood sugar, which were already associated with these drugs. Health experts urged closer monitoring for patients with cardiovascular risk factors.

October 30, 2008: FDA Requests Information on Once-Daily Seroquel Formulation

The U.S. Food and Drug Administration requested additional data from AstraZeneca regarding its application to market a once-daily version of Seroquel XR. Regulators sought clarification on safety concerns, particularly the drugโ€™s potential to cause weight gain, diabetes, and cardiac complications. The request delayed approval as the agency continued to review post-marketing data.

December 2, 2008: Side Effects of Seroquel and Zyprexa Linked to Heart-Related Deaths

A new analysis found that atypical antipsychotics such as Seroquel and Zyprexa significantly increased the risk of fatal heart conditions, particularly among elderly patients. The study contributed to growing evidence that these medications posed serious cardiovascular dangers, prompting calls for stricter warning labels.

January 20, 2009: Seroquel Diabetes Side Effects Increase Risk by 389 Percent

Data published in a peer-reviewed medical journal indicated that patients using Seroquel had nearly four times the risk of developing type 2 diabetes compared to those on older antipsychotic drugs. Researchers cited metabolic disruptions and insulin resistance as key contributing factors. The findings further validated thousands of legal claims already pending against AstraZeneca.

February 10, 2009: Seroquel Diabetes Problems Kept from Doctors, Report Finds

An internal analysis revealed that AstraZeneca had known of elevated diabetes risks associated with Seroquel for years but failed to disclose the full extent to physicians. The report alleged that selective publication of study data minimized awareness of serious side effects. Medical experts criticized the lack of transparency and urged stronger regulatory oversight.

March 30, 2009: Seroquel Side Effects Lead to FDA Concerns

The FDA issued new warnings after receiving hundreds of adverse event reports linking Seroquel to diabetes and severe weight gain. Regulators cautioned prescribers to monitor blood sugar and lipid levels in patients taking the drug. The announcement intensified scrutiny of AstraZenecaโ€™s marketing practices and post-approval safety monitoring.

July 14, 2009: Side Effects of Seroquel and Zyprexa for Children Under Review

Federal health officials launched an investigation into the use of Seroquel and Zyprexa among children and adolescents, following reports of dramatic weight gain and metabolic issues. Pediatric psychiatrists warned that the drugs were often prescribed off-label without adequate safety data. The review sought to determine whether additional restrictions were warranted.

September 15, 2009: Generic Schizophrenia Drug Carries Lower Death Risk Than Seroquel

A large-scale study comparing antipsychotic medications found that older generic drugs were linked to lower mortality rates than newer brand-name treatments like Seroquel. Researchers attributed the difference to metabolic complications and cardiac side effects associated with atypical antipsychotics. The findings reignited debate over the safety advantages of modern formulations.

February 2, 2010: Seroquel Diabetes Side Effects Data Withheld from U.S. Doctors

Documents obtained during litigation revealed that AstraZeneca shared more complete data about Seroquelโ€™s diabetes risks with European regulators than with U.S. physicians. The disparity raised questions about whether the company selectively disclosed safety information to maintain sales in its largest market. The revelations fueled public criticism and legal scrutiny.

March 5, 2010: Seroquel Weight Gain Problems Hidden from Doctors

Medical experts accused AstraZeneca of downplaying Seroquelโ€™s link to significant weight gain, citing internal correspondence indicating that unfavorable trial results were suppressed. The allegations reinforced claims that the company prioritized marketing over patient safety. Consumer advocates called for tougher penalties for selective disclosure of study data.

May 25, 2010: Zyprexa and Seroquel in Children Cause Dramatic Weight Gain, Studies Find

Clinical research confirmed that children and adolescents taking Seroquel or Zyprexa experienced extreme weight gain and metabolic disturbances within months of treatment. Pediatric specialists warned that the side effects could lead to lifelong health problems, including diabetes and heart disease. The studies prompted demands for stricter prescribing guidelines for minors.

June 22, 2010: Antipsychotics for Dementia Blamed for Deaths in Elderly Patients

Researchers linked Seroquel and other antipsychotic medications to thousands of premature deaths among elderly dementia patients. The findings intensified calls for black box warnings against off-label use in this population. Regulators later emphasized that the drugs were not approved for behavioral management in dementia care.

August 5, 2010: Zyprexa and Seroquel Side Effects in Children Require Urgent Review

A joint medical advisory committee urged further review of Seroquel and Zyprexa use among young patients, citing ongoing reports of rapid weight gain and hormonal imbalance. The panel recommended expanded post-marketing surveillance and better education for prescribers on metabolic monitoring protocols.

October 21, 2010: Seroquel Weight Gain Side Effects Suppressed in Company Research

Investigators uncovered evidence that AstraZeneca altered internal reports to understate Seroquelโ€™s impact on weight gain. The suppressed findings showed significant metabolic disruption even at standard doses. The controversy deepened skepticism toward the companyโ€™s credibility and raised questions about pharmaceutical data transparency.

June 10, 2011: Ethics Violation Found Over Seroquel Weight Gain Statements

A review board concluded that AstraZeneca violated ethical standards by making misleading statements about Seroquelโ€™s weight-related risks in marketing materials. The inquiry found that company representatives downplayed adverse data when communicating with healthcare providers. The ruling added to growing criticism of industry influence over medical information.

September 22, 2011: Suicide Risk Spurs Bill Limiting Seroquel Prescriptions in Military

A congressional report prompted legislation to restrict the use of Seroquel among U.S. military personnel after data suggested a link between the drug and increased suicide risk. Lawmakers called for comprehensive review of prescription practices within the Department of Defense. The measure highlighted concerns about psychiatric drug safety among active-duty service members.

November 18, 2011: Seroquel Approved for Depression in Europe

European regulators granted AstraZeneca approval to market Seroquel XR for major depressive disorder, expanding its use beyond schizophrenia and bipolar disorder. The decision came despite ongoing litigation and safety controversies in the United States. Critics warned that the expanded indication could expose more patients to serious side effects.

January 6, 2012: Study Finds Antipsychotic Drugs Increase Risk of Blood Clots

A population-based study published in BMJ found that users of antipsychotics such as Seroquel faced a significantly higher risk of developing venous thromboembolism. Researchers urged clinicians to weigh cardiovascular and clotting risks before prescribing. The findings added another layer of concern to the drugโ€™s evolving safety profile.

July 17, 2013: Seroquel Heart Side Effects Warning Issued

Health officials issued updated warnings about the potential for Seroquel to cause irregular heartbeat and sudden cardiac death. The FDA recommended that physicians monitor cardiac function in patients with existing heart disease or electrolyte imbalances. The announcement marked one of the most serious safety advisories since the drugโ€™s introduction.


413 Comments


kathryn
i started taking seroquel in 2004 i gained 100 pounds and i’ve had a hard time getting the weight off. i think to myself how can a medicine company be so cruel; knowing that this medicine can cause diabetes and even death

Mario
This Drug is not approved for anyone under the age of 18.I say that because I read that it is being prescribed to children.How can anybody be so irresponsible.Thats criminal.I wonder how many children under State care are being given the drug.They are supposed to be taking care of these children.These drugs should never have been approved by the FDA.I can’t believe the horror stories I have read about Drugs intended for Adult use being given to children.Thats insane.State Agencies should know better and adults should Never give them to their children no matter what a doctor says or thinks.There should be a Class Action Lawsuit for Parents that have their kids under temporary care of their state that prescribed this drug for there kids.The same goes for giving it to Elderly people .Their bodies can’t cope with it.

lhuff
I failed to mention in my last post that my mother was only 58.

lhuff
My mother passed away 2 weeks and 2 days ago. I am uncertain at this point how long she had been taking Seroquel, but all of the things that she has been experiencing for awhile, I am 100% this drug shortened my mother’s life. It should be taken off the market. My mother was having blackouts, pain in her back and knees, she could barely stand for more than 5 min. She was having shortnes of breath, she was so tired she could barely eat to regulate her high blood sugars. My mom in the past year had signs of not remembering programs she had watched and conversations she had had with her chldren, The night before the morning of her death she awoke at 2:26am delirious and and confused. Her blood sugar was high. She fell back to sleep and never woke up. Her symptoms had been going on for months and everything became worse…and worse…my mom would be so tired she couldn’t eat a full meal without falling asleep and at times my brother and sister stated she would fall asleep right infront of them with food in her hands. she was confused alot. Fainting is reported with this drug. She was on 800 mg a day. She also had cataract surgery, which is reported as well. I don’t feel that any physcian should even prescribe this drug to a person on diabetes. Prescription suicide!!! my mother also gained weight and complained about that often. NO one should be using this drug from the research I have been discovering.

Amanda
I write this in concern of my father . My father has been prescribed Seroquel for many years during this time he has attempted suicide several times.

robin
i was on serquel 300mg and my blood glucose went to 1472 in january of 2009 and found out i was now a diabetic type 2 my doctor took me off the serquel and my blood glucose came down and now i live with the diabetes

Maria
I have been taking seroquel for the last 4 months. I am currently on 400mg at night and 100mg of Piramax for the migraine headaches. I used to have daily migraines before starting the meds but since starting them I have not had a single migraine. I am 1.6m tall and used to weigh about 36 to 38 kg. I was never able to pick up any weight no matter what I did. I have to note here as well that I had a thyroidectomy at the age of 22 due to an extreme overactive thryroid that did not respond to medication. I now weigh about 45kg. No more being underweight for me! For 15 years I was treated with antidepressants and it made my life a living hell. I am now 39. Eventually found a doc that was willing to listen to me and found out that I was having a bad reaction to the serotonin stuff in the meds – had a mini stroke because of Zoloft. The doc admitted me to hospital and changed my meds to the current ones and slowly increased my meds until we found a level that worked for me. For the first time in my life I am feeling like a normal human being and I can sleep, think and concentrate. I would normally go for 72 hours without sleep during a manic phase and physically exhaust myself completely just to be able to sleep for an hour or two. On a “normal” day I would go to bed, close my eyes and sleep but stillbe aware of everything that is going on around me. I am bipolar manic, anxiety disorder and borderline schizophrenic as well as ocd. I have made a point of drinking lots of water during the day and to stay away from anything that is a quick “pick me up” like caffiene, chocolate or refined sugar. I have found that when I do have something like that I tend to get extremely hungry and irritated. So I avoid it all together. Maybe it helps somebody else out there as well. I am just happy that I have found something that works for me and I hope that everybody else will also find what works for them. And that I found a doctor that is responsible and takes the responsibility for his patients and does what is best for them. The previous ones I had definitely did not do that.

Karen
I am currently taking 500 mg of Seroquel in the morning and 500 mg at bedtime. I have been taking Seroquel for at least 3 years. I also have experienced problems with weight gain, cholesterol and other lipids. The weight gain was not an issue with me because compared to what I gained when I took Zyprexa this was nothing. However, I have been trying to lose weight and it just seems impossible. I am wondering if the Seroquel might be hindering my attempts? Also, I seem to be taking a very large dose of this med. Is anyone else taking 1000 mg a day?

Harry
My son was put on 10 mg in the am and 200 mg at bedtime just 3 weeks ago for a possible mood disorder. He already wants no part of it. He can’t stay awke at school. After reading all these posts I’m scared to death. His doctor says its a great drug. I’m thinking about taking him off but dont know what the happen. any suggestions? can you do it cold turkey or do you have to ween yourself off?

Gracie
My name is Gracie, I was placed on Seroquel in 2006 . something is not right, for years i have not been able to sleep after a sleep study at night no results where found so they did a day study they said it was a sleep disorder that i needed to take seroquuel to sleep and concerta to keep awake threw the day. I also suffer from depression PTSD from years of abuse as a child. I have tried all kinds of meds for sleep and my panic dis, no results anyway i started Seroquel, I could sleep ! the past 7months i have gotten worse very tired mood swings, muscle pain nosebleeds weight gain 38 pnds bowl problems stomach pin and bloating not feeling well at all my eye sight is know bad have growth over my eyes not sure if its cateracs . but sense all this I have dropped my dose more than half want to get off of this drug ,and i wont sleep but at least im alive god help us all.

Dee
Lets make this easy. If you are a researcher for the drug company or involved in the FDA approval process or attorney or family member of those listed or work for Astra Zenica and take Seroquel, just raise your hand. Why spend 600 million thus far to prove how good it is for you? Just raise your hand…Case closed….drug taken off market, those injured compensated. Do it again and we will make you and your children take the drugs

Bill
I totally agree with Steve from Sydney. My VA psychologist prescribed seroquel about two bottles ago @ 25mg for sleep and hallucinations. I feel like I am roasting most of the time, sweat all night and my energy level has dropped significantly. I feel like I want to sleep all day and have no idea what my cholesterol is like. Currently taking simvastatin 80mg already. I suffer from depression and PTSD from my military service. I have tried marijuana recently and found it to work just like Steve put it. I could replace all my other medications with one natural herb with which there is no known toxicity, except I would be considered a criminal. I do not understand this world. Because of money people cannot heal themselves, because of money people have to go to a foreign country and slay thousands, because of money pharmagiants can feed people pills that kill. nuff sed

frank
i started taking seroquel in 2004 for bi polar issues. i started with low doses but now by october 2008 i was put on 800 mg a day i gained weight had all kinds of side effects. i went to the doctor for blood work and was diagnosed with type 2 diabeties. there is no diabeties in my family history. now i have to take 3 other types of meds for my diabeaties. my life has become totally unmanageable i am currently on social security disability who ever you are dont ever take seroquel it will ruin your life in very horrible ways frank p

Steve – Sydney Australia
I’m Apparently “Bipolar”. I been on 400mg for past 2Weeks. Pains in the Chest both sides. Dry Mouth & Throat. Sweating heaps under Armpits. (Never have before) & it’s Winter here. Now I’ve Seen this thread …. OMFG!! I’m exteremly worried. Cannabis seems to Work Very Well & Keeps me Balanced … Cannabis Stops the Suicidal Thoughts. But NO , I’m a Criminal the Govt Say & Face being sent to Prison if I grow 2 plants. Drs have Also Recommended I use Cannabis. The System is A Total Mess.

Amy
My husbands doctor prescribed him seroquel for bipolar. The doc wanted him to get to 2000mg. At 1400mg he ended up in the hospital. He almost died. His kidney’s started to shut down. He now suffers severe memory loss and health issues due to seroquel.

Rory
Seroquel is a strong drug, prescribing 25mg alone can put you to sleep and 30+ lbs over time( Me) But you guys say your doctors gave you 200-300mg thats suicide. That can surely cause death and it will always affect air and blood flow to the head. If you take that much then you will surely gain atleast 60 pounds mostly in the stomach, and it should really kill you but if you are healthy then you wont feel any side effects for a while. It will be sudden. Those of you who took blood test and see problems, stop immediately. 25mg is enough and if your body is weak take half of that. A doctor must never give a old person or someone who is a bit weak such a strong drug and in such high quantity.

Anthony
One year ago July 11 2008 I was hospitalize into ICU VA Hospital Indiana for being a walking coma with a glucose blood count of 905 I did not know why until the doctor told me I have diabeties I was shock it dose not run in my family as being a carry of the deadly decease. I did some research and found out that It was the seroquel I had been given by the VA Hospital Indianapoplis, Indiana when I told them they denied it and thank to CNN New July 22 when it was broadcasted worldwide

manny
does anyone know of it’s link to a high suicide rate iv’e never attemted im 39 well since feb 09 iv’e tried twice both times w/my quill DO NOT DO THIS! EVER! but im thinking ther is more to this crappy drug then diabetes??

ricky
I ‘am going on age 17 and over 2 years ago my parents had forced me to take this evil, toxic drug. it was as if i was an experiment subject for the docs, like a lab rat. Now days, i currently have type 1 diabetes.

janet
My husband was admitted to the senior behavioral assesstment hospital.he had parkinsons’ dementia and he was given haldol as well as seroquil and I explained he should not be on Haldol but he said he was combative and continued to give it to him.Hia feet and ankles started swelling so bad and I made a issue about it . Every time I wud visit he was drugged and was so thirsty and wanted to go to the bathroom. They the staff got so mad because he wanted to go to the bathroom. He was so confused he did get angry. They had him in a diaper all the time and didn’t have baths for days at a time.Eventually they were increasing his seroquil and he went down so fast , He was drugged every time we went there. within 3 weeks he was rushed to the emr of the other hospital and they said he didn’t have a pulse when he got there, he was gone. they said he had heart attack . So because these doctors are administering drugs they do not know enough about. If I have my way about all of this I will not let anyone of these senior citizens suffer from that treatment again,Good luck to all of you fighting your diseases. Try to get off of the medicine before you all die too.

Noah M.
I just took Seroquel for 5 weeks. My stomach and chest are hurting badly. I just went off it. I don’t know what to do or who to see. Nobody is understanding that this is really hurting me. I’m nervous. I don’t feel right. Something is wrong with my stomach and causing me pain. I took it for insomnia and mild depression due to economy. Now I’m worse off with health issues. I should have drank tea and gone to accupuncturist for stress. I don’t feel good.

Elizabeth
My husband was unhappy & having anxiety attacks. The doctor told him he was experiencing depression. This was in December. He was prescribed Seroquel, an anti-psychotic. He was not schizophrenic & was healthy & mental well all years previously. After being on it for only a week, he was sleeping most of the day & felt groggy & disoriented upon wakening. His mood did NOT improve. After 4 months on the drug, he put a bullet into his head. I am now a widow after almost 25 years. Read these posts.

Julie
Since starting Seroquel, I have gained over 50 pounds and have not been able to lose it. I fear that I am now dependant on it because it helps me sleep. I have tried all other drugs in the same classification and also other sleep aids, but am always forced to return to Seroquel. Treating my Bipolar has been a real bitch these past 10 years and since starting Seroquel I’ve had mixed results. Nightmares, lucid dreams and weight gain versus being able to fall asleep. Sometimes waking after the dreams I get leaves me shaken all day to the point that I can’t focus at work. I’m running out of drugs to try. Feels like I’m stuck with the extra weight and nightmares, theres no alternative it seems.

Ann
I have taken seroquel for about five years 300mg nightly. I have been having a lot of health problems breathing ,anixeity,heart,weight gain , and other issues.

Joe
May God have mercy on those in the FDAwho approved seroquel.

janice
I took it for 7 years and I gained over 80 lbs in about 5 years plus im a borderline diabetic….I hope that they have to take it off the market.

Pam
I have been on Seroquel for several years. I think it is a wonderful medicine. Anti-depressant meds had terrible side effects. I am bipolar. Since taking Seroquel, all of my bipolar issues have disappeared. I am no longer depressed. I sleep great at night. No adverse side effects at all. I have actually found that I lost weight after I started Seroquel, so not everyone who takes it gains weight. I was in seriously bad shape for about 10 years until I got put on this magic drug.

joegenavasi
I have been taking 600 mh of Seraquil every night for sleep for 10 years know. I have lost all sensation in both my feet and gained 200 lbs. All i eat is raw beets and water and i still can’t loose the weight. I run ( waddle ) 12 miles 6 times a week and I still love St Alphonono’s Pankake Breakfast with Nanook – Goos luck myt fellow fellowe

Carrie
I have NEVER weighed more than 140 but am usually 120. Now I am 180 a year after starting seroquel. I started at a 25mg dose and ended on a 600mg dose before I was told to stop immediately because I had the first seizure of my life last week. I have unvoluntary hand movements, weight gain, a diabetes worry, very high cholesterol, and many more issues including various pain throughout my body and swollen feet. Since doctor told me to stop immediately, I’ve already started losing weight and haven’t even started working out yet. I hate the drug though and do not recommend it to anyone.

Susan
My post will probably not be posted since I do not have a negative thing to say about Seroquel, except the extreme hunger and craving of sweets, but even that has not caused me any undue weight gain. I suffer from scleroderma with secondary pulmonary arterial hypertension along with lupus and other auto immune diseases. Due to these conditions, sleep eluded me. My rheumatologist put me on a low dose (25 mg) of seroquel to help me sleep 3 years ago. It has done it’s job, no more, no less, with no increase in dosage. My blood work shows no ill effects from the drug and is checked and monitored very closely by my doctor. It concerns me that so many people in the posts I read were taking such large doses to sleep. I can possibly understand the large doses for bi-polar conditions or schizophrenia, but not just sleep. My sleep is good on 25 mg. without feeling groggy in the morning. Any drug can be dangerous if not used properly. It is up to our doctors to prescribe medications properly. If they are unsure about the side effect of a particular drug, then it should not be prescribed, especially to the elderly. It is also up to us to be in charge of our own healthcare. When your doctor prescribes something, ask about the side effects. If the doctor does not know them or if they are too unpleasant for you, ask you doctor to make an alternate choice for you and keep doing it until he/she gets it right. Afterall, they DO work for you.

Cara
All i have to share is while I was on Seroquel is that my A1C was through the roof! My physicians prescribed this for me and i took it as I was told. I slept for days on this drug. Now that I’ve taken myself off, I can’t get to sleep without a miracle from God. My body seems like it’s attacking me and I’m so fatigued. I feel like an 80 year old. This is absolutely poison.

Fran
When my daughter passed away on March 5th 2008 she had diabetes very bad , she was on seroquel and she took a fatal cocktail overdose of alot of meds and she ended her life. She was awfull on seroquel we didnt know her as the same person her bi-polar had gone from bad to horrible she couldnt stay awake etc. Please Dont take this drug it is not safe. Yeah they tell you its OK but it is not. She left 4 children whom miss her so much. A wasted life because of this Drug. If you have any questions about this drug serch the internet it will tell you.

Nevan
My father was diagnosed with Parkinson’s Disease and given the usual medication. Then he became delusional and the doctor put him on Seroquel. Even though he was healthy and had no other medical problems, he became almost paralyzed, and then died from cardiac arrest about 3 months later. He had all the symptoms of neuroleptic malignant syndrome. Seroquel was not approved for use with elderly patients with dementia at the time, in fact it was recommended NOT to use it. How could the doctor have been so uninformed? The doctor said cause of death was “Lewy body disease.”

Linda
I was put on both Zyprexa and later Seroquel for a bipolar disorder. Weight gain, a cholesterol disorder, increased alcohol and mania followed. I have finally found a psychiatrist who was able to see that the environment and wrong meds were my problem and have gone off all atypicals. I read the recent article in Rolling Stone magazine exposing Ei Lilly and others. I have been an advocate and healer in the field of mental health for many years. Seeing all the vulnerable individuals who have been victimized by these toxic drugs has enraged me! I don’t want to get mad (never a good idea for a bipolar person!) I want to get EVEN!

Heather
2 years agiI was in love with a great guy who was prescribed Seroquel, a month later he committed suicide..yes he had depression and had tried before but he changed dramatically and wanted to stop taking it but the nurse prac. and the counselor both told him not to stop taking it…I have since talked to two other people that have taken this drug and they have also said they had severe reactions to it…one said it messed with his mind and the other ended up in the hospital after feeling like she was going to die because her heart rate slowed down so much. The FDA needs to make sure of these drugs and the doctors need to research these kind of drugs before they just prescribe them to just anyone.

TOMESHIA
SINCE I BEEN TAKEING SEROQUEL OFF AND ON FOR OVER15YEARS AND HAVE BEEN DIAGNOSED WITH diabetes TYPE 2 .. I DEVOLPE THIS HUGER ITS HORRIBLE AM ALREADY OVER WEIGHTโ€ฆSTART AT 25MG IN 1996 THEN THE OLD I GOT THE MORE MG I WAS GIVING THE TRY TO GIVE ME 1500MG A DAY GOOD THING FOR MEDCAICD WOULD NOT PAY FOR IT SHORT AFTER MY FEET WAS SO BIG I WAS PUT IN THE HOSPTIAL FOR ONE WEEK TOLD ABOUT THE DIABETES . STILL GIVEN SEROQUEL 400MG AT BEDTIME WHEN I TOLD MY DOCTOR SHE INCREASED IT TO 600MG TWICE DAILY ANYONE ..GAINING WEIGHT IT LIKE 125POUNDS

Leslie
Since I started taking Seroquel I’ve packed on over 40lbs in 5 months!! I have never been this heavy and NEVER gained weight so fast in my life. Althought I crave sugar, I can’t attribute all the weight to extra calories. The weight is also almost all in my midsection which is extremely unhealthy. I also have severe heartburn and RLSI can’t go off of it or I suffer severe withdrawal symptoms and can’t sleep. I wish I never would have started on this drug..

brea
i was diagnosed with bi polar disorder in march of 2007 . i had just detoxed off of a number of narcotics. i started originally on 25mg of topamax , gradually having my dose moved up by 25mg until i was at 75mg. i was placed on seroquel in april of 2007 50mg to ‘stabilize’ any mood swings, within a month i was up to 100 mg of seroquel and exsperencing nosebleeds almost every day. my MD told me this was normal and to look else where in my history for an explanation . within 4 months i was taking 150mg of seroquel a day. when i found out i was pregnant in late 2007 i asked my MD to lower the dosage of seroquel as it passes threw the placenta in to the fetus,”due to the extra plasma in my blood at the time ” it was altered by 100mg more after i had my child instead of lowering my medication it was upped again too the new long lasting seroquel as it stands i’m on 500mg long lasting seroquel in just over 2 years of being diagnosed & 00mg topamax, since then I’ve been diagnosed with thyroid disease as well and high cholesterol neither of which i had before and i routinely get checked. to this day i still get nose bleeds that last for up to thirty mins followed by migraines, migraines that last for days, dizzy spells, confusion, forgetfulness, muscle cramps, muscle spasms, occasionally blackouts and recently partial seizures. in no medical dictionary is it written that seroquel is a mood stabilizer nor is it to be prescribed for bi polar disorders but i suppose I’m not a professional so i wouldn’t know

Sherri
I was prescribed Seroquel for Bi-Polar Disorder in 2000. I did not take the drug regularly until I had an episode late in 2007. The doctors had me on a dose of 800mg initially. They dropped it to 600mg. In August, I had a horrible reaction to Seroquel that caused me to lose all mobility by developing tardive dyskensia. I am now highly succeptible to that side effect. Had may partner not recognized what was happening, the outcome would have been worse.

Seroquel Diabetes Suit Scheduled to Begin June 29 in Delaware State Court : AboutLawsuits.com
[…] the dismissal of two Seroquel diabetes suits that were scheduled for trial last month in federal court, the first case that will be heard by a […]

tammie
My husband was bipolar and i would say about 5 years ago he was put on seroquel. He started out as doing fine but he was not able to sleep so they increased his dosage. after the increase he began sleep walking and he would speak about things that made no sense during the day. He never had these problems untill seroquel. On dec 8th 08 he passed away of a heart attack. He was 39 years old and the cause of death was listed as seroquel by the coroners office and also on his death certificate. His daily dosage was 1200 mg a day. (600mg in the morning and 600mg in the eve. ) i blame the people who made this medication because if it wasnt for them he would still be here for his three children. (He did have a heart condition no one knew about but seroquel caused his heart attack) Seroquel took my husband dont let it happen to you to. Thank you for your time. Tammie

Seroquel Diabetes Problems Kept From Doctors According to Unsealed Documents : AboutLawsuits.com
[…] to documents unsealed last week in the federal Seroquel litigation, AstraZeneca encouraged their sales representatives in 2005 to tell doctors in the United States […]

Lisa
I am 38 yr old female in may 2003 I was diagnosed Bi-polar (depressed w/severe anxiety.I went through the pill mill and ended up with Seroquel, Topamax, and now klonipin.Since Sept 2003 I have been taking Seroquel.Since this time I have watched my health go down like I was 80. Shortly after being on Seroquel I was put on Inderal La to regulate my heart rate then 3 surgeries to remove cyst .My teeth were horrible all of a sudden know I have dentures.I was gaining weight and no matter what I did could not get it off applied for S0ocial security still fighting that cholesterol then heart attack jan 2008.This year moderate body swelling just had multiple test because my lymphoid is swollen as well and just found out I have hypothyroidism.I currently take 15 meds a day almost as many as my grandmother who has leukemia.To this day I have gained 125 lbs and I eat no more than the days before I was diagnosed the only difference is I sleep more and have no energy and I know part is the heart attack but I am 38 and I feel so old.

jacquie
My 15 year old daughter was prescibed seroquel 3 months ago and she has had horrible side effects: bleeding nose, fainting, rapid pulse rate and also a faint pulse.She has been diagnosed with acute dystonia as well. Her muscles have become very rigid and she aches all over.She has had hallucinations and nightmares.I do NOT recomend this drug and have since taken her off of it.She is till suffering from the muscle rigidness.Also a concern of ours is that her ca125 levels came back raised after taking this drug.ca125 is a marker for breast and ovarian cancer.I am waiting her ultrasound results as i write this.

Dawn
Seroquel is a horrific drug. My son started taking it 8 years ago. He was in good physical health. He was bipolar and was given different drugs but he seemed to reallly like the Serloquel and said he was addicted to it. He could not sleep without it. Within the 8 years he developed insulin dependant diabeties. He gained approximatly 200 lbs. He has been in and out of hospitals and not for psych reasons. All medical related. He was hospitalized for pancreatitis last year. He was admitted to the hospital early in the morning of Feb 12, 2009. He was complaining of pain in his abdomen and said he felt like he did when he pancreatitis. They ran tests and took xrays. His triglycerides were over 9,000. I talked to him that night on the phone and he sounded very medicated. Duladid every 4 hour and 800 mg of Seroquel a day. They said he had gallstones but were not going to treat them now. Feb 13, 2009 the Dr.s made rounds and wrote discharge instructions for him. He had been up walking around and by 10:36 am he was pronounced DEAD. His pancrease DIED. He was 37 years old.

angie
I have been taking seroquel for about 5 years. I have had weight gain and back and belly pain. I am on 600mg at bedtime. I have severe pain and my belly is so swollen I actually look like I am pregnant. My gain is only in the belly. I cannot have a bowel movement without enough misc over the counter medicine to give an elephant a good bowel movement. Even after all the meds I have 1-2 movements and they are not very productive. The following day or 2 and it is back to the severe swelling. I have went to the ER and no help was given. Even after 2-3 weeks with out a movement, no help was given. I also have the gambling and obsessive disorders that I have read about in these postings. So much of this info hits home. I just am concerned about the pain and a solution. If there is help out there, whether it be a lawsuit or a solution I am all for it. I have takaen so much time away from my family, especially my 2 little ones, because of the pain and embarrassment of looking like I do with my belly. That time cannot be regained.

Marcia
Was 6taken of my sleeping meds have had prblemssince strokes and doc put me on seroquel it made me ill in month in half even though warnings if had stroke and so on with my medical history of 12 auroinnune diseases and previously before my strokes had type 2 diabetes from steriods. He took me off then got not sure of spelling keyadadosis. Treated with baking soda then found out had hypo glycemia with outbreaks of type 2. I now am passing white celss in urine and other kidney problems even sugar in urine and other problems loosing control of bladder and bowel problems since this. I have sought help yet no luck and have lost weight to pont of still lossing 50 lbs now in last two months. Getting very ill. Need help live in missouri have heard fromlawyers they have already settled to keep trying but so ill hard to family is now having to do all for me am insulin intolerant yet cant stand the highs of the juice needed and havve to see a special doc for approval to get med needed for hypoglycemia beings allergif even to glucofage and causes me to go to low so now waitintg on state since on disability

Gabriel
I have been taking seroquel for about 3 to 4 years.And have gained 60 lbs. And in 2008 developed diabetes.My sugar with medication is still between 200 to 300 everyday.Diabetes has changed my whole life for the worse

Elizabeth
I’ve been taking Seroquel on a trial basis. I was diagnosed as being bipolar and the medicine was to help me sleep. I later read that it can also cause suicidal thoughts. I had a situation where I was severly depressed for a week straight and got to the point where I thought ending my life would be the best route. One night I drank half a bottle of Bacardi then decided to take 28 sleeping pills. I refused to go to the hospital because I did not want to be put in a psych ward so my husband and friends made me throw up. It helped because I woke up the next day. But the thoughts still come when I get down and had my doctor told me these were one of the risks I would never have started taking them. Even though I haven’t seen my doctor in almost 6 months, he gave me enough to where I could make them last and to be taken when need be. My husband is really concerned because he’s scared one day he will come home to a dead wife.

diane
got diabetts after taking this drug.

This field is for validation purposes and should be left unchanged.

Share Your Comments

This field is hidden when viewing the form
I authorize the above comments be posted on this page
Post Comment
Weekly Digest Opt-In

Want your comments reviewed by a lawyer?

To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.

NOTE: Providing information for review by an attorney does not form an attorney-client relationship.

MORE TOP STORIES

Plaintiffs and defendants have submitted a joint schedule for a final pretrial conference before the second Bard PowerPort lawsuit bellwether trial over claims the port catheter is defectively designed.
Analysts expect wider use of breast reconstruction mesh through 2030, even as lawsuits raise questions about synthetic products, FDA approval and serious complications requiring additional surgery.