Side Effects of Fluoride Exposure May Lower Child IQs: Study

Researchers noted that levels of water fluoridation in the United States were too low to effectively use in the study.

While adding fluoride to drinking water is widely recognized for preventing tooth decay and cavities, a new federal study suggests it may also be linked to lower IQ scores among children.

In a study published in JAMA Pediatrics on January 6, researchers revealed that higher fluoride consumption in drinking water is associated with lower IQ scores in children. The research found that for every 1 mg/L increase in fluoride levels in urine, there was an average decrease of 1.63 IQ points, suggesting a potential causal relationship.

The United States began adding fluoride to the public water supply in the 1950s. While some groups opposed the practice, it became more widespread in many cities nationwide.

Some studies have indicated water fluoridation is beneficial for dental health. However, other research has linked fluoride to adverse side effects, such as posing a risk to the intellectual development of children.

In September 2024, a California judge ruled that fluoride in public water decreases children’s IQ, and called on the U.S. Environmental Protection Agency to review acceptable levels of fluoride in drinking water. Following that ruling, research published in October 2024 warned adding fluoride to drinking water did not decrease dental cavities, but instead increased the likelihood of dental fluorosis by about 40%.

For this latest study, researchers from the National Institutes of Environmental Health Sciences, led by Dr. Kyla W. Taylor, performed an analysis of 74 cross-sectional studies conducted in China, Canada, Denmark, India, Iran, Mexico, New Zealand, Pakistan, Spain and Taiwan. The team examined fluoride in drinking water at levels less than 4 mg/L, 2 mg/L, and less than 1.5 mg/L. They also measured fluoride in urine at the same levels.

None of the analysis was conducted in the U.S., because fluoridation levels in drinking water are much lower than in the other countries studied. Countries with higher levels of fluoride in the water are better able to highlight the evidence linking fluoride and lower IQ scores, according to researchers.

Researchers said they found a “significant inverse association” between fluoride exposure and children’s IQ scores. Among fluoride measurements taken from the participant’s urine, the data showed an IQ score decrease of 1.63 points for every 1 mg/L increase of fluoride in the urine. Average levels of fluoride in the urine range from 0.5 mg/L to 3.5 mg/L in the United States.

In addition to measuring levels of fluoride in urine, researchers also compared IQ to levels added to drinking water, finding an IQ score decrease of 1.14 points for every 1 mg/L increase of fluoride in the water.

Overall, higher fluoride levels were linked to lower IQ scores in children, researchers determined, concluding that the findings from the analysis will help inform the risk-benefit assessment of using fluoride in children’s tooth care.

“This systematic review and meta-analysis found inverse associations and a dose-response association between fluoride measurements in urine and drinking water and children’s IQ across the large multicountry epidemiological literature,” the researchers concluded. “These findings may inform future comprehensive public health risk-benefit assessments of fluoride exposures.”