Acomplia, Weight-Loss Drug, Linked to Deaths and Suicide

Sanofi-Aventist SA’s weight loss medication, Acomplia, which is not available in the United States, has been linked to five deaths and more than 2,000 reports of adverse reactions in the United Kingdom. The drug was rejected by the U.S. Food and Drug Administration (FDA) in June 2006, due to a risk of self harm and suicides, but it was approved by the Medicines and Healthcare Products Regulatory Agency (MHRA) in London approximately two years ago.

One of the five deaths linked to the drug was a suicide, which raises further concerns about the psychiatric side effects of Acomplia. The MHRA conducted a review last year of reported depressive reactions in as many as 10% of patients taking the drug, and added stronger warnings to the labels about psychiatric side effects. Doctors and patients were warned to stop the medication if depression was reported while taking the drug.

In January 2008, the FDA instituted a new policy which requires drug manufacturers to examine whether patients become suicidal during clinical trials before they will approve a medication in the United States. The policy was developed following the discovery that several medications which were given FDA approval could carry an increased risk of suicide, including certain antidepressants and Chantix, a drug designed to help people quit smoking.

Did You Know?

AT&T Data Breach Impacts Millions of Customers

More than 73 million customers of AT&T may have had their names, addresses, phone numbers, Social Security numbers and other information released on the dark web due to a massive AT&T data breach. Lawsuits are being pursued to obtain financial compensation.

Learn More

According to the National Health Service in England, over 100,000 prescriptions were written for 20-miligram doses of Acomplia last year. Sanofi says that they are working with regulators to continue monitoring the safety of the drug. In addition to the suicide, other deaths associated with the drug included two from heart problems, one from an infection and one sudden death with a cause that has not yet been determined.

0 Comments

Share Your Comments

I authorize the above comments be posted on this page*

Want your comments reviewed by a lawyer?

To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.

NOTE: Providing information for review by an attorney does not form an attorney-client relationship.

This field is for validation purposes and should be left unchanged.

More Top Stories

Master Baby Food Lawsuit Filed in MDL Outlines How Toxic Metals Caused Autism, ADHD in Children
Master Baby Food Lawsuit Filed in MDL Outlines How Toxic Metals Caused Autism, ADHD in Children (Posted 2 days ago)

Plaintiffs have submitted a baby food lawsuit Master Complaint that is expected to streamline the filing of lawsuits alleging that toxic heavy metals in Beech-Nut, Gerber, Hain and Nurture products caused ADHD, autism and other developmental disorders.

Lawsuit Claims AGGA Device Damaged Teeth, Resulting in Disfiguring Injury
Lawsuit Claims AGGA Device Damaged Teeth, Resulting in Disfiguring Injury (Posted 2 days ago)

Another AGGA device lawsuit has been filed by a man who says he had to have the device surgically removed less than a year after having it implanted due to jaw problems and migraines.