Alli Lawsuits

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The over-the-counter weight loss drug Alli, which contains orlistat, has been linked with reports of serious and potentially life-threatening liver damage.

In May 2010, the FDA required a new warning about the risk of Alli liver problems after identifying multiple reports of liver failure, liver transplant and death among users of orlistat-based medications.

ALLI LAWSUIT STATUS: Product liability lawyers are monitoring information about the risk of liver injury from orlistat to determine whether users who have experienced problems may be entitled to compensation through an Alli liver damage lawsuit.

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MANUFACTURER: GlaxoSmithKline, PLC.

OVERVIEW: Alli (orlistat 60mg) is a lower dose, over-the-counter version of the prescription weight-loss drug Xenical (orlistat 120mg). It was approved by the FDA in 2007 for use in overweight adults in conjunction with a reduced calorie and low-fat diet. The drug works by preventing the absorption of fats, thereby reducing caloric intake.

Alli generated sales of $131 million during its first full year on the market. Known side effects of Alli include oily and loose stools, fecal incontinence, frequent or urgent bowel movements and flatulence, which tend to be most severe when the treatment is started and may decrease with time.

ALLI LIVER SIDE EFFECTS: In August 2009, the FDA issued an early communication indicating that they were reviewing the risk of liver problems associated with Alli side effects after receiving reports of liver injury associated with use of the drug.

On May 26, 2010, the FDA announced that it had found at least 13 cases of liver injury with orlistat worldwide, including at least one case of Alli liver problems in the United States. The reports involved cases of liver failure, liver transplant and death.

The most commonly reported side effects were a yellowing of the skin or whites of the eyes, known as jaundice, weakness and abdominal pain. The FDA has not determined that there is a definite association between liver injury and Xenical or other orlistat drugs, but users of Xenical should contact their health care professional if they experience symptoms of liver injury, including:

  • Weakness or fatigue
  • Fever
  • Jaundice
  • Brown Urine

64 Comments


Kristie
I took Alli for about 3 months a few years ago. I never took more than recommended, actually less. Within 2 months I was in the hospital with severe constipation. I had my first colonostocpy at the age of 32, major GI issues. I was overall healthy prior to taking this drug, Cronic diarrehia, constipation, unable to tolerate most foods, hiatal hernia, GERD and severe pain is all I have now. I just had my gallbladder removed, never did I have issues prior to using this drug. I am still undergoing tests, scared of what is next.

Janet
Im a 27yo healthy but slightly heavey female who started alli 4 mos ago,2 mos into it & 30lbs gone I stopped alli and thats when my GI problems started, nausea,vomitting & diarrehia. My symptoms increased to the point where I couldnt work and ran up doctor bills doing upper endoscopy,ultrasound,hida scan,ct with contrast dye and multiple trips to ER. I just had gallbladder removed yesterday!! I hope this takes care of my problems and I learned my lesson, i was happy & healthy being fat! I really hope nobody else suffers like I did, I wish I found these postings before I took alli,its ruined my life,i’ll never be the same thats forsure,one organ less!!!

myokia
i took alli when it first came out and then started it again in august of 2010 . in octomber of 2010 i ended up in the hospital and found uout that i had pancreatitis.

Jeannie
WOW!! This is Amazing. I am a 35 yr old who was a healthy hyper always running about girl 2 1/2 years ago. I took Alli for about a month. I never thought anything about it. I developed chronic severe diarrhea and lost my rectum. It got deattached and fell out and again as of several days ago and has also made my vagina pushed out. Another surgery. Wow. This is Unbelievable. Please feel free to contact me at any time. This has completely changed my life. Thank you for sharing!! & I wish you the Very Best!! Kindest Regards, ~Jeannie

Tracy
I took Alli several years ago for a few months. About a year later I found out I have a liver problem and was on steriods for over a year to control it. I now have diabeties & cholesterol problems that I never had before. They could not figure out what caused the liver problems. From what I have read I believe it was the Alli. I still have a bottle of it in my cabnet I will keep as proof. DO NOT USE ALLI IT IS Dangerous.

shanda
I have only been taking Alli for a short time. Today, I woke up with a swollen neck, all the way from my chin to my collar bones. Has anyone else experienced this? Also, the entire surface area of my abdomen is sore to the touch. Has anyone else experienced this? Does anyone have any suggestions of what it could mean? I am stopping the Alli pill. I didn’t even know it was dangerous, my mother called me and begged me to stop it after doing a search about it on the web. I’m going to the doctor’s tomorrow just to be safe. I don’t know what else to do, my neck is so swollen.

Gina
I took Alli when it first came out in 2007. I was not considered as obese. I just wanted to lose 10lbs. I was healthy with no bad habits such as smoking or drinking. After about a month I quit taking it because I did not like the side effects. Since then I have I had GI problems. I had to have my gallbladder removed. Now, I am still having problems. I have undergone many tests and have been diagnosed with chronic pancreatitis. I am 34-years-old and do not fit the description for someone who would have chronic pancreatitis! I do not drink and have no family history of pancreatic problems. Two days ago I found my receipt of when I purcahsed the Alli. I couldn’t believe it! I will be holding on to it as proof! I think Alli is responsible for my GI problems!

Barbara
I took alli for one year and became very ill and i am still on medication for damaged liver i still have very bad itching. I wish they would take it off the market so other people will not suffer the way i have. Prior to takin alli i was perfectly healthy-not obese and not taking any meds

vickie
took alli damaged my pancreas. had tail of pancreas and spleen removed, im always sick.

monica
I have taken alli in the past and started taking it again ,only to find out how bad it is for you. i was just told last week i have a fatty liver . i will never take this alli pill again . I took it to help me get healthy ,and know to find out i may have damaged my liver. This sickens me.

Marcia
I am 32 years old and took ALLI for about 6 weeks. I was recently only taking 1 or 2 pills a day and I am having bloody bowel movements. I have an appointment to have it checked by my doctor. These posts have me scared…I feel sick! I reported my symptoms to GSK and they called me the next day. They know something is up. Why would they continue to make a drug that is killing people…I was healthy and just a little chunky before taking this drug and now I could have a serious health issue.

Christina
I to used Alli for a couple of months and also had bowel movements and my self. About 4 months later i was diagnosed with severe ulcerative colitis and in july and aug i had two emergency surges to removal all of my large intestines. i lost so much blood i had to receive a total of 7 units of blood. i just want some answers and why is there not a lawsuit against them for colon/intestines damage. Im only 27 so what am i suppose to do now and about to lose the last 4 inches of my rectum.

Dan
I too was a regular user of Alli. My use extended over a period of about a year and six months. Do not assume rectal-bleeding are hermorroids. After about 3 or 4 months, I was bleeding, continued taking it anyway. Come time to get a colonoscopy, the doctor found colon-rectal cancer. I stopped taking it after the scope immediately. Went to google Alli and a cancer study in mice determined colon-cancer in alli fed mice. So now, I got the picture and am waiting to see if the cancer mestatized to liver. Yea, had pre-chemo and radiation. Rectum removed and part of colon and 25 lympnodes, Get the picture!! No post chemo for me, Be sure to have a K-Ras test done before anyone proposes Chemo is you have colon-rectal cancer.

Amber
My brother and I had taken Alli for only a couple of months when it first came out on the market. Both of us are overweight and wanted to try it in conjunction with a healthy diet. When we both started having bowel incontinence and/or horribly painful bowel movements we stopped taking Alli thinking it would solve the problem, It’s now November of 2010 and we both still suffer from bouts of bowel incontinence and severe pain. It affects us in so many ways. It has made us late for work, caused embarrassment in public places, and ruined a lot of clothes. I would never suggest anyone taking this pill to lose weight it has changed mine and my brothers lives permanently for the worse.

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