High-Dose Folic Acid During Pregnancy May Increase Cancer Risk for Children, When Mother Also Takes Epilepsy Drugs
Nitrous Oxide Lawsuit Individuals who suffered harm, or families who lost a loved one after using nitrous oxide products may be eligible for financial compensation through a nitrous oxide lawsuit.
Hair Relaxer Lawsuit Regular exposure to chemicals in hair relaxer may cause uterine cancer, ovarian cancer and other injuries. Women diagnosed with cancer may be eligible for settlement benefits.
Depo-Provera Lawsuit Depo-Provera lawsuits are being investigated for women who developed meningioma brain tumors after receiving Depo-Provera birth control shots, claiming that Pfizer failed to adequately disclose side effects.
Ozempic Lawsuit Lawyers are pursuing Ozempic lawsuits, Wegovy lawsuits and Mounjaro lawsuits over gastroparesis or stomach paralysis, which can leave users with long-term gastrointestinal side effects
Suboxone Tooth Decay Lawsuit Lawsuits are being pursued by users of Suboxone who experienced tooth loss, broken teeth or required dental extractions. Settlement benefits may be available.
Change Healthcare Lawsuit Lawyers are reviewing Change Healthcare class action lawsuits for individuals who had their personal information stolen due to the data breach.
AngioDynamics Port Catheter Lawsuit Serious and life-threatening injuries have been linked to problems with Bard PowerPort. Lawsuits are now being pursued by individuals who suffered injuries from the implantable port catheter fracturing or migrating.
Bard PowerPort Lawsuit Serious and life-threatening injuries have been linked to problems with Bard PowerPort. Lawsuits are now being pursued by individuals who suffered injuries from the implantable port catheter fracturing or migrating.
Processed Food Lawsuit Lawsuits are being pursued against the food industry over their manufacturing and advertising of ultra-processed foods, which have caused a generation of children to face an increased risk of developing childhood diabetes and other chronic illnesses.
AFFF Lawsuit Exposure to firefighting foam chemicals may result in an increased risk of cancer for firefighters, military and airport personnel.
Depakote Birth Defect Risk Highlighted in New Study June 10, 2010 Staff Writers Add Your Comments The side effects of Depakote, a popular anti-seizure medication, and other valproate-based drugs could be linked to a number of major birth defects when used by pregnant women, according to the findings of a new study. European researchers published the results of a new study on the Depakote birth defect risk in the most recent issue of the New England Journal of Medicine. The researchers found that using Depakote increased the risk of six major types of birth malformation, including spina bifida, cleft palate, abnormal skull development, malformed limbs, holes in the heart, and problems with the urinary tract. Depakote (dilvalproex) and other valproate-based anti-seizure medications, usually used to treat epilepsy, have long been associated with birth defects. Late last year the FDA added more stringent warnings about birth defects to Depakote and other drugs in the same class, which also includes Depacon, Depakine and Stavzor. Learn More About Depakote Lawsuits Side effects of Depakote use during pregnancy may cause birth defects, delays. Learn More SEE IF YOU QUALIFY FOR COMPENSATION Learn More About Depakote Lawsuits Side effects of Depakote use during pregnancy may cause birth defects, delays. Learn More SEE IF YOU QUALIFY FOR COMPENSATION The latest study helped to quantify risks based on different types of birth defects from Depakote. Researchers looked at data collected from eight published cohort studies where women were exposed to valproic acid during their first trimester. Their results indicated that exposure to Depakote during early pregnancy could cause significant increased risk of a variety of birth defects. They found that taking the epilepsy drug resulted in a 12-fold increased risk of spina bifida, and a 7-fold increased risk of craniosynostosis (abnormal skull). There was also a five-fold increased risk of cleft palate, and 2.5 times the risk of atrial septal defect (a hole in the heart). Earlier data gleaned by FDA from the North American Antiepileptic Drug (NAAED) Pregnancy Registry found that the use of valproate during pregnancy increases the risk of major birth defects and malformations. In particular, the risk of giving birth to a child with a neural tube defect was 1-in-20 for women who took valproate during the first 12 weeks of pregnancy. The risk for mothers not taking valproate was 1 in 1500 in the U.S. The NAAED Registry reported that more than 10% of women who took an average of 1,000 mg per day of Depakene or Stavzor during pregnancy gave birth to children with some kind of major malformation. Other birth defects whose risks are increased include craniofacial defects, cardiovascular malformations and malformations of other body systems. Pregnancy problems with Depakote have been long recognized. A “black box” warning has been on the medication’s label since 2006, warning about potential Depakote birth defects associated with use of the drug during pregnancy. A study done that year found that about 20% of babies born to mothers taking Depakote suffered serious problems, as opposed to other drugs which only had rates of between 1% and 10.7. Researchers in the most recent study concluded that use of Depakote and similar antiepilepsy drugs significantly increased the risks of specific birth defects during the first trimester, meaning that the damage could be done before a woman is aware she is even pregnant. Abbott Laboratories, the creator of Depakote, is currently being probed by the U.S. Department of Justice (DOJ) over its sales and marketing of the drug. Federal investigators are looking into whether the company violated Medicare or Medicaid reimbursement laws. Depakote was first approved by FDA in 1983. Depakene, the first drug of the class, was approved in 1978. Tags: Abbott, Birth Defect, Cleft Palate and Lip, Depacon, Depakene, Depakote, Epilepsy, Epilepsy Drug, Stavzor Image Credit: ||| More Depakote Lawsuit Stories Both Epilepsy and Anti-Seizure Drugs Increase Osteoporosis Risk, Study Warns June 15, 2023 Depakote Use During Pregnancy Linked to Psychiatric Problems in Childhood, Study Warns April 20, 2023 High-Dose Folic Acid During Pregnancy May Increase Cancer Risk for Children, When Mother Also Takes Epilepsy Drugs October 4, 2022 3 Comments curtis May 25, 2011 Has anybody had any issues with children with birth defects while the father was on medication. Melinda January 27, 2011 My son was born with a unilateral cleft lip and palate and craniel malformation back in 1995. I was using Depakote to control my seizures. I was told about the risk of Depakote causing Spina Bifida. It did not have a black box warning back then and other craniofacial abnormalities were not listed along with heart malformations. I believe his cleft palate has direct correlation with me taking Depakote. We had to see a Genetic Counselor after he was born to determine cause and effect. The is no one in our family history being born with cleft lip and palate. They stated it could be a direct cause of the medication I was taking. I tr to tell myself that if I did not take my medication it would of been worse for my child because self pity will not help him only I can. Kim June 14, 2010 I am the mother of a 3 year old girl born Feb. 2007. My daughter was born with hypotonia from head to toe, had breathing problems immediately following birth, was placed on oxygen at 2 months of age (24-7) and that lasted over a 3-4 month period. At 10 months of age she had to have brain surgery where they placed a VP shunt in her head due to her cerebrospinal fluid not draining. She will have this for the rest of her life. She has also been diagnosed with developmental delay and has a physical therapist, occupational therapist, early childhood special education teacher, and a speech therapist. I have constantly wondered if the amount of depakote (1000 – 2000 mg BID) which I was taking at the time of my pregnancy had something to do with my daughter’s problems. Share Your CommentsFirst Name*Last NameEmail* Shared Comments*This field is hidden when viewing the formI authorize the above comments be posted on this page Yes No Post Comment I authorize the above comments be posted on this page Weekly Digest Opt-In Yes, send me a weekly email with the latest lawsuits, recalls and warnings. Want your comments reviewed by a lawyer?To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.Contact Phone #Alt Phone #Private CommentsNOTE: Providing information for review by an attorney does not form an attorney-client relationship.CAPTCHAGA SourceGA CampaignGA MediumGA ContentGA TermNameThis field is for validation purposes and should be left unchanged. Δ MORE TOP STORIES Ozempic Side Effects Caused Stomach Paralysis and Severe Abdominal Pain, Lawsuit Claims (Posted: yesterday) A product liability lawsuit filed against Novo Nordisk accuses the drug maker of failing to provide adequate warnings of Ozempic side effects, like stomach paralysis. MORE ABOUT: OZEMPIC LAWSUITOzempic Gastroparesis Lawsuit Filed Over Nausea, Severe Abdominal Pain (04/04/2025)Ozempic Delayed Gastric Emptying Led to Stomach Paralysis: Lawsuit (03/27/2025)Court Urged To Reject Motion To Dismiss Lawsuits Over Ozempic, Mounjaro Gastrointestinal Risks (03/21/2025) More Than 12,000 Hair Relaxer Cancer Lawsuits Filed Against L’Oreal, Other Cosmetics Companies (Posted: 2 days ago) Nearly a dozen different cosmetics companies face more than 12,000 hair relaxer lawsuits, involving claims that chemical straighteners caused women to develop uterine cancer, endometrial cancer, ovarian cancer and other injuries. MORE ABOUT: HAIR RELAXER LAWSUITUterine and Endometrial Cancer Caused by Hair Relaxer Products: Lawsuit (03/25/2025)Schedule for Hair Relaxer Lawsuit Bellwether Trials Outlined by MDL Judge (03/13/2025)Synthetic Braiding Hair Contains Cancer-Causing Chemicals: Consumer Reports (03/05/2025) Paraquat Settlement Reached for Parkinson’s Disease Lawsuits Filed in MDL (Posted: 3 days ago) Lawyers involved in Paraquat Parkinson’s disease lawsuits pending in the federal court system indicate that they have reached an agreement to settle many of the claims. MORE ABOUT: PARAQUAT PARKINSON’S DISEASE LAWSUITSAppeals Court Urged To Reinstate Paraquat Lawsuits Previously Set for Bellwether Trials (02/14/2025)Paraquat Lawsuits Over Parkinson’s Disease Risk Set for Trial in October 2025, April 2026 (01/29/2025)Farmers Exposed to Certain Pesticides Face an Increased Risk of Rheumatoid Arthritis (12/11/2024)
Depakote Use During Pregnancy Linked to Psychiatric Problems in Childhood, Study Warns April 20, 2023
High-Dose Folic Acid During Pregnancy May Increase Cancer Risk for Children, When Mother Also Takes Epilepsy Drugs October 4, 2022
Ozempic Side Effects Caused Stomach Paralysis and Severe Abdominal Pain, Lawsuit Claims (Posted: yesterday) A product liability lawsuit filed against Novo Nordisk accuses the drug maker of failing to provide adequate warnings of Ozempic side effects, like stomach paralysis. MORE ABOUT: OZEMPIC LAWSUITOzempic Gastroparesis Lawsuit Filed Over Nausea, Severe Abdominal Pain (04/04/2025)Ozempic Delayed Gastric Emptying Led to Stomach Paralysis: Lawsuit (03/27/2025)Court Urged To Reject Motion To Dismiss Lawsuits Over Ozempic, Mounjaro Gastrointestinal Risks (03/21/2025)
More Than 12,000 Hair Relaxer Cancer Lawsuits Filed Against L’Oreal, Other Cosmetics Companies (Posted: 2 days ago) Nearly a dozen different cosmetics companies face more than 12,000 hair relaxer lawsuits, involving claims that chemical straighteners caused women to develop uterine cancer, endometrial cancer, ovarian cancer and other injuries. MORE ABOUT: HAIR RELAXER LAWSUITUterine and Endometrial Cancer Caused by Hair Relaxer Products: Lawsuit (03/25/2025)Schedule for Hair Relaxer Lawsuit Bellwether Trials Outlined by MDL Judge (03/13/2025)Synthetic Braiding Hair Contains Cancer-Causing Chemicals: Consumer Reports (03/05/2025)
Paraquat Settlement Reached for Parkinson’s Disease Lawsuits Filed in MDL (Posted: 3 days ago) Lawyers involved in Paraquat Parkinson’s disease lawsuits pending in the federal court system indicate that they have reached an agreement to settle many of the claims. MORE ABOUT: PARAQUAT PARKINSON’S DISEASE LAWSUITSAppeals Court Urged To Reinstate Paraquat Lawsuits Previously Set for Bellwether Trials (02/14/2025)Paraquat Lawsuits Over Parkinson’s Disease Risk Set for Trial in October 2025, April 2026 (01/29/2025)Farmers Exposed to Certain Pesticides Face an Increased Risk of Rheumatoid Arthritis (12/11/2024)