FDA Investigating Blood Clot Risk from Yaz Birth Control

Federal investigators have launched a safety review of Yaz, Yasmin, Beyaz and similar birth control pills, after several recent studies have suggested that the drugs carry a greatly increased risk of blood clots

On May 31, the FDA announced it was initiating a safety review that includes all oral contraceptives containing the new “fourth” generation progestin drospirenone; including Yaz, Yasmin, Beyaz, Safyral and generic equivalents.

The review was sparked by the findings of at least two studies that found that drospirenone-based birth control carried two to three times the risk of blood clots than some other pills.

Did You Know?

AT&T Data Breach Impacts Millions of Customers

More than 73 million customers of AT&T may have had their names, addresses, phone numbers, Social Security numbers and other information released on the dark web due to a massive AT&T data breach. Lawsuits are being pursued to obtain financial compensation.

Learn More

The announcement also came just days after the European Medicines Agency officially determined that the side effects of Yaz, Yasmin and similar pills were associated with a higher risk of venous thromboembolism (VTE) [PDF] when compared to older levonorgestrel-containing pills and recommended that the labels be updated. Both the FDA and its European counterparts note that the overall risk of a blood clot is still small.

The studies that sparked the FDA review were published in the British Medical Journal, and determined that women taking Yaz and Yasmin were twice as likely to have a blood clot than women taking levonorgestrel-based pills. The FDA notes that some prior studies found no evidence of an increased blood clot risk.

The FDA announced that the goal of the Yaz and Yasmin safety review is to fully assess the risks and benefits of drospirenone-based drugs and that it will release new safety information to the public as it becomes available.

Drospirenone is a newer type of progestin that is usually used in combination oral contraceptives that also include estrogen. It was originally introduced by Berlex Laboratories in Yasmin. Once Berlex was acquired by Bayer Healthcare an updated version of Yasmin was introduced called Yaz. More recently, Bayer introduced a third version, marketed as Beyaz, which includes a folate supplement.

Some experts say that drospirenone disrupts the body’s normal mechanism of regulating a balance between salt and water. This results in elevated potassium levels, known as hyperkalemia, which can cause potentially life-threatening heart problems and other health issues.

In addition to Yaz, Yasmin and Beyaz, drospirenone is also used in the brand name birth control pill Safyral, as well as generic Yasmin equivalents sold as Ocella, Syeda and Zarah, and generic Yaz equivalents sold as Gianvi and Loryna.

Bayer currently faces about 7,000 Yaz lawsuits, Yasmin lawsuits and Beyaz lawsuits, which allege that the drug maker has failed to adequately warn about the increased risk of health problems associated with the birth control pills. The complaints have been filed on behalf of women who have suffered heart attacks, strokes, pulmonary embolism, deep vein thrombosis, gallbladder disease and other serious injuries after using Yaz, Yasmin, Beyaz or other drospirenone birth control pills.

Image Credit: |

1 Comments

  • AlejandraOctober 2, 2012 at 7:41 am

    In High School, I had very painful Ovarian Cysts and was put on the pill. Never had a prlboem for 11 years. came off it to get pregnant. Stayed off for 6 years then started having super heavy periods. Was put on what the OBGyn called a strong' pill to control the flow and 2 months later ended up in the hospital with blood clots in my lungs. Couple of years on blood thinners and I will never [Show More]In High School, I had very painful Ovarian Cysts and was put on the pill. Never had a prlboem for 11 years. came off it to get pregnant. Stayed off for 6 years then started having super heavy periods. Was put on what the OBGyn called a strong' pill to control the flow and 2 months later ended up in the hospital with blood clots in my lungs. Couple of years on blood thinners and I will never take the pill again.

Share Your Comments

I authorize the above comments be posted on this page*

Want your comments reviewed by a lawyer?

To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.

NOTE: Providing information for review by an attorney does not form an attorney-client relationship.

This field is for validation purposes and should be left unchanged.

More Top Stories

Management of Ozempic Lawsuit Pretrial Proceedings To Be Reassigned Following Death of MDL Judge
Management of Ozempic Lawsuit Pretrial Proceedings To Be Reassigned Following Death of MDL Judge (Posted 3 days ago)

The judge overseeing Ozempic lawsuits consolidated in federal court has died, requiring a new judge to be assigned to oversee coordinated pretrial proceedings over claims the diabetes drug and similar medications caused stomach paralysis and other intestinal complications.