Invisalign Invisible Braces Linked to Reports of Serious Allergic Reactions

• RafaelAugust 3, 2023 at 10:10 am

  I've been having a lot of health problems. Dry mouth, sore throat, tonsil stones, shortness of breath, insomnia, blurry vision. I have a hormone Imbalance, my back hurts on the very top part ( feels like my Adrenal area. Very tight chest like something is sitting in my chest. All of this started when I got invisilign. I noticed that when I wear the retainer at night. My back pain starts all ov[Show More]I've been having a lot of health problems. Dry mouth, sore throat, tonsil stones, shortness of breath, insomnia, blurry vision. I have a hormone Imbalance, my back hurts on the very top part ( feels like my Adrenal area. Very tight chest like something is sitting in my chest. All of this started when I got invisilign. I noticed that when I wear the retainer at night. My back pain starts all over. In the day time when I don't use them, I feel less pain. I will not wear them to see what happens. Reading all of this, connects the plastic to all my symptoms. I want my health back. No one talks about this. It's insane and scary that we have to look for answers on our own. Living in the best country in the world and having the technology. I guess our health is not important.

• E Dayton OHJuly 1, 2023 at 11:48 pm

  It took me several weeks before I realized what was going on. I was 49ish two years ago when I started my invisalign journey. About the third week into it, my tongue started tingling. The next week my throat tingled. Then it started to burn. The next week it was burning my esophagus. The next week it was burning my belly and my eyes. My lips were somewhat swollen. My face was a bit pinker than nor[Show More]It took me several weeks before I realized what was going on. I was 49ish two years ago when I started my invisalign journey. About the third week into it, my tongue started tingling. The next week my throat tingled. Then it started to burn. The next week it was burning my esophagus. The next week it was burning my belly and my eyes. My lips were somewhat swollen. My face was a bit pinker than normal. I suspected it was the invisalign but I had already put $1000 deposit down and really didn't want to stop. By the 6th week, I was waking up in the middle of the night because it was so painful. I had to stop. My orthodontist said he'd never heard of any problems but he didn't charge extra for me to start over with metal braces and didn't have any problems with them. I just got my braces off about two months ago. I do have to wear plastic retainers 24 hours a day for 3 months. I'm watching for signs this time. I do have to say, I feel cold rather than burning. in my esophagus and roof of mouth but it could be because of GERD at my age. After 3 months, I only have to wear them at night. I can ask to switch to Hawley but it wasn't recommended.

• KarenJune 19, 2023 at 6:07 pm

  After 2 days wearing Invisalign aligners, I lost my tastebuds. Everything tasted TERRIBLE. Eating became a problem. I lost 10+ lbs which may sound great BUT it was NOT. My orthodontist sent me to an Oral Medical Specialist 45 minutes away for treatment. I had to fill & mix prescriptions, then "rinse and swish for 3 mins, 4 times a day" for about 2 months. This unfortunately, caused me to mis[Show More]After 2 days wearing Invisalign aligners, I lost my tastebuds. Everything tasted TERRIBLE. Eating became a problem. I lost 10+ lbs which may sound great BUT it was NOT. My orthodontist sent me to an Oral Medical Specialist 45 minutes away for treatment. I had to fill & mix prescriptions, then "rinse and swish for 3 mins, 4 times a day" for about 2 months. This unfortunately, caused me to miss the entire Thanksgiving and Christmas seasons. After 2 months, wearing no aligners, I started Clarity 3M aligners on 1/16/20. I am about to start wearing RetainerClub.com aligners but the packaging has an allergy warning. I contacted my orthodontist, who referred me to Retainer Club. He said is not aware of any patients having allergic reactions to Retainer Club aligners. That is what he said about Invisalign and I know how that turned out:( Invisalign treatment began 11/18/19 and ended the morning of 11/20/19. I also posted about the allergic reaction online (don't recall which one).

• AlisonJune 3, 2023 at 11:00 am

  On Feb, 2023, after only 8 days of Invisalign, my son suffered his first ever tonic colonic seizure at 17 years old. He continued to wear the braces, even during the EEG, which showed brain activity leading to a diagnosis of epilepsy. He was placed on the maintenance medicine Keppra. Seven weeks and 5 days later, he suffered another seizure. At that time, he was still wearing them but we discont[Show More]On Feb, 2023, after only 8 days of Invisalign, my son suffered his first ever tonic colonic seizure at 17 years old. He continued to wear the braces, even during the EEG, which showed brain activity leading to a diagnosis of epilepsy. He was placed on the maintenance medicine Keppra. Seven weeks and 5 days later, he suffered another seizure. At that time, he was still wearing them but we discontinued them and notified the orthodontist the following day. He hasn't worn them since and hasn't had a seizure since and we're wondering if there is a connection. Invisible braces have shown to contain trace amounts of benzene, which can cause seizures.

• EdmondMay 23, 2023 at 9:38 pm

  Is anybody experiencing uncomfortable bloating? If so any suggestions for remedy? I typically start getting bloated around the same time in the afternoon and it last all night. Nothing else has changed in my life except for wearing Invisalign!

• LiesaMay 14, 2023 at 10:49 pm

  I had extreme fatigue! I mean extreme, had to stop treatment but the Ortho Doctor didn’t believe me that I was reacting to them!! And is still charging me $6,000!! Even though I stoped treatment after 2 weeks!!!

• MariMay 2, 2023 at 1:36 pm

  Anyone that has had any kind of reaction that is not normal, please go to FTC.gov and file a claim under product fraud. I filed my claim after finding out my seizures, trigeminal neuralgia, severe periodontal disease and loss of multiple teeth with need for implants. If you look up Hexane 1,6 you will find most of your symptoms. It's toxic and not for oral use.

• CarolineMarch 8, 2023 at 7:11 pm

  Noticeable soreness, irritation and ulcers gradually happening after moving onto the nighttime vivaris retainers. Can't stand it and removed them tonight. What a waste of money. I did wonder about my almost constantly swollen glands in the throat. Very validating to read of all the comments as I thought I was overreacting.

• SamanthaMarch 5, 2023 at 3:07 pm

  I honestly feel like these plastic retainers ruined me. I couldn't swallow to the point that watermelon and eggs were too hard to get down. I simply couldn't eat. I started wearing them in 2018. I stopped after a little over a year when I realized they were seriously ruining my health. It's 2023 and to this day I find my mouth super dry, gasping for air in the night, anxiety and still trouble swa[Show More]I honestly feel like these plastic retainers ruined me. I couldn't swallow to the point that watermelon and eggs were too hard to get down. I simply couldn't eat. I started wearing them in 2018. I stopped after a little over a year when I realized they were seriously ruining my health. It's 2023 and to this day I find my mouth super dry, gasping for air in the night, anxiety and still trouble swallowing pills. It's sad when you get anxiety about swallowing 1 advil. I have never had trouble swallowing, and since these retainers I always feel like im choking. I dont even like to eat without someone being home. I was recently pregnant and couldnt even take my prenatal vitamins or an antibiotic that was prescribed to me. I used to be able to swallow 6 advil at once and never experienced any kind of anxiety in my life. Hopefully one day I will feel normal again. Huge mistake!!! I would never allow either of my children to use these aligners.

• BrenJanuary 31, 2023 at 1:12 am

  I have been using Invisalign for nearly 4 years now with no issues but I believe I have developed an allergy. I woke up about a week ago (I wear my nightly retainer) and my entire tongue is so painful and swollen. Right where the sides of my tongue touches the retainer are the worst. I also have a constant sore throat, not a sick feeling type but a pain leaking down from my tongue. Inside of my ch[Show More]I have been using Invisalign for nearly 4 years now with no issues but I believe I have developed an allergy. I woke up about a week ago (I wear my nightly retainer) and my entire tongue is so painful and swollen. Right where the sides of my tongue touches the retainer are the worst. I also have a constant sore throat, not a sick feeling type but a pain leaking down from my tongue. Inside of my cheeks and lips are swollen as well. I took a couple nights off from wearing it and it started to go down a bit. Then tonight I tried putting them in for 5 minutes and instantly the swelling increased again. I am calling my dentist tomorrow. It is so uncomfortable and hard to eat and even speak.

• NancyJanuary 30, 2023 at 3:14 pm

  I wore my retains for 4-5 months and experienced a lot of the symptoms reported here in these comments; shortness of breath, stomach issues. etc. I did not associate them with Invisalign. I went in for an appointment and was told the retainers were not tracking correctly and I would need to have new ones and that would prolong the treatment. I had what they told me what a simple case. I did not w[Show More]I wore my retains for 4-5 months and experienced a lot of the symptoms reported here in these comments; shortness of breath, stomach issues. etc. I did not associate them with Invisalign. I went in for an appointment and was told the retainers were not tracking correctly and I would need to have new ones and that would prolong the treatment. I had what they told me what a simple case. I did not want to go backwards and only had one more tray or so left, so I asked to have my case stopped and retainers made. It is when I went in to get the "buttons" removed that changed everything for me. They grind them off and smooth off the teeth. I had about 14 buttons. The next day my mouth felt like it was on fire and I had a sort of mucous film all over my mouth that I could not get rid of. I went back to dentist for a cleaning thinking it was a gum infection. They said no, and gave me a RX for Gerd. I didn't understand how one day my mouth was fine and the next I had Gerd and my mouth was completely changed. I finally found this site and was relieved. I thought I was losing my mind. I wrote a letter to the dentist and the office letting them know I believe I had a reaction to the trays and the removal of the buttons and their material. No response from them. It has been almost a year and although I can breathe better and my stomach issues have gone away, my mouth is a mess with the film substance that will not go away. The only relief is when I am eating or drinking or chewing gum. The dental offices/ortho offices should be telling patients about potential side effects so they can make informative decisions about treatment.

• ElenaJanuary 21, 2023 at 2:37 am

  I am a 40 y.o. old female and soon after I started wearing Invisalign, something bad to started to happen to my body. Initially, I could not associate that condition to Invisalign, because my dentist has not warned me of any side effects. First, I began to have rashes/itchiness on my body and face together with angular cheilitis. Then I started to have a feeling of a throat closing and tightness[Show More]I am a 40 y.o. old female and soon after I started wearing Invisalign, something bad to started to happen to my body. Initially, I could not associate that condition to Invisalign, because my dentist has not warned me of any side effects. First, I began to have rashes/itchiness on my body and face together with angular cheilitis. Then I started to have a feeling of a throat closing and tightness, difficulty breathing, hives on my chest, headaches, fatigue. I went to all types of doctors, undergone various blood tests, nothing abnormal was detected. At some point I was told I had a severe allergic reaction but yet I could not relate it to Invisalign. The things were getting worse and worse, I barely could breathe and my chest was covered by itching hives. Fortunately, I found this page, and took Invisalign out. My condition started to improve immediately. However, a month after I took them out, I am still not ok, some symptoms persist. Letting the doctors know about having worn Invisalign for 6 months, they prescribed antihistamines and blood cleansing IFs. I read some research saying that plastic dental braces could leach toxic harmful chemicals. I hope to recover one day sometimes soon and become the one I used to be. I wonder how many other people wearing plastic dental braces are not feeling well and are not able to find a cause of their condition.

• Concerned MotherJanuary 9, 2023 at 5:05 am

  My daughter had the metal braces but when finished, needed a retainer. Her Ortho provided the invisiline retainer for her top teeth (different type of retainer for bottom teeth). 24 hours later, I noticed a rash around one of my daughters eyes. It gradually moved to both eyes. It also included swollen lips. Has anyone experienced a rash using the invisiline retainer post braces?

• TinaDecember 15, 2022 at 5:48 pm

  I’m so glad I found this page and as I’m reading similarities between my reactions and others I know my orthodontist definitely didn’t have my best interest in mind when I consistently complained to her about these things. The lip swelling and tingling in my tongue was happening for awhile and the more intense night sweats. Then more recently I experienced something scary like someone else on here[Show More]I’m so glad I found this page and as I’m reading similarities between my reactions and others I know my orthodontist definitely didn’t have my best interest in mind when I consistently complained to her about these things. The lip swelling and tingling in my tongue was happening for awhile and the more intense night sweats. Then more recently I experienced something scary like someone else on here which was the scalp pressure! I thought all sorts of things and was getting so scared something was really wrong. I continued to tell my Ortho and she dismissed & continues to dismiss my issues to this day. I have a few more months until I finish my treatment but I’ve had these for almost 3 years now because she didn’t want to listen to me until the doctor finally say I needed a bone graft due to the aligners. She then ordered a new set to be made to correct this halfway through so now I have to keep these things in even longer in addition to my retainer at the end! I’m not happy with Sage Dental and how they handled this at all. They tried to make me think I was ridiculous for thinking this and at one point the Ortho and a few staff literally laughed in my face when I voiced my concerns. If you can avoid Invisalign and Sage dental in Plantation, Florida, please do by any means necessary!

• PeterDecember 8, 2022 at 2:01 pm

  lots of posts here is there a class action lawsuit coming? or are all these posts just fake? I can confirm i might have issues as well with invisalign causing stomach bloating and burning sensation in small intestine locaiton

• JENNIFERNovember 22, 2022 at 11:01 am

  I've been wearing invisalign on and off since 2019 my mouth has become dry, lost my taste, and constantly have a film like presence in my mouth, any one else have this?

• MNovember 20, 2022 at 5:10 pm

  I started Invisalign in 2019 only to stop using it in two weeks due to unspecific or general malaises: throat, lymph nodes swelling, and headaches. I blamed the symptoms on my hypothyroidism and got back to using it for reduced hours. Noticed each time w/ Invisalign use, the symptoms returned, turned to m dentist for the issue---This is the weird portion of the dentist's I thought: the dentist le[Show More]I started Invisalign in 2019 only to stop using it in two weeks due to unspecific or general malaises: throat, lymph nodes swelling, and headaches. I blamed the symptoms on my hypothyroidism and got back to using it for reduced hours. Noticed each time w/ Invisalign use, the symptoms returned, turned to m dentist for the issue---This is the weird portion of the dentist's I thought: the dentist led me to a private room for my issue which the issue was handled quietly and "stealthily" avoided addressing the issue by suggesting the issue to slow use for the 5 years termed Invisalign. The unscrupulous practice left me in dark and the symptoms evolved over the years. In 2020, i used it 4 hours a day and not every day but in 2021, I ran to ER for heart palpitations, shortness of breath, tingling in all four limbs, and throat swelling. I finally decided to look into this product for the side effects but this website was not out front and up. In 2022, I ran to the ER two times and each time, symptoms were similar and worsening, recommending to see a cardiologist. I could see bright red blood in my spit, pain shooting from my throat to my head, and upper chest and back pain. I stopped using it and it took a month to feel a bit better. I will be seeing a cardiologist next week however, finding this webpage gave me a better insight into evolving symptoms since using the product. Here is one question though. Is it really a snake oil incident a stupid customer buys into? Or it is an undisclosed and overlooked product safety measurement by the Consumer Product Safety Commission that we pay tax to? People get hurt when regulatory bodies and law-making bodies are distracted. Where are the accountabilities for the product maker, and really these dentists who are unscrupulously promoting the toxic product at the expense of lives? How many people should be hurt to get the attention of our tax-paid agencies to act on it?

• MoniqueNovember 13, 2022 at 9:51 pm

  I am so glad I came across this website, I started my Invisalign a little over two weeks ago. The first night I had them in I woke up with what felt like hot flashes, night sweats and a headache. The next morning I felt an overall feeling of malaise and what felt like fast really fast heart rate. In general my blood pressure is always pretty low, and I’m a healthy person who eats well. Years ago [Show More]I am so glad I came across this website, I started my Invisalign a little over two weeks ago. The first night I had them in I woke up with what felt like hot flashes, night sweats and a headache. The next morning I felt an overall feeling of malaise and what felt like fast really fast heart rate. In general my blood pressure is always pretty low, and I’m a healthy person who eats well. Years ago I was diagnosed with IBS and Gerd. I thought maybe it’s a flare up? But how could that be? I learned years ago what diet works for me and I stick by it religiously. I then thought, maybe I’m getting sick? Well, over the past couple of weeks symptoms only worsened. I began having chest pains, on the left side of my body. Neck pains, and when I would eat it was kind of hard to swallow, my tongue also felt tingly on the tip. Then came the stomach pains along with feeling really bloated everyday. The last few days I also started having sores on my bottom inner lip, I thought maybe I’m biting my lip in my sleep or something? I literally did not put it together until yesterday evening, Saturday. I literally sat up and thought, oh sh** am I allergic to these retainers?? I took them out immediately, I finally slept well and all day today I have felt SO much better. These things were actually poisoning me! Now I have to call my orthodontist tomorrow and see what can be done? I doubt I’ll get a refund back. I will never wear Invisalign again and I definitely would never recommend them.

• CandiNovember 3, 2022 at 10:58 pm

  I experienced tongue selling and sores as well as mouth pain that would keep me awake at night. I gradually wore the Invisalign less. Then graduated to the permanent upper and lower lingual bar. Over a few weeks, I experienced mouth and tongue sores, my lips swelled and my tongue would bleed. I was told that one gets used to the bars so stuck with it. My lips burning was keeping me from sleeping[Show More]I experienced tongue selling and sores as well as mouth pain that would keep me awake at night. I gradually wore the Invisalign less. Then graduated to the permanent upper and lower lingual bar. Over a few weeks, I experienced mouth and tongue sores, my lips swelled and my tongue would bleed. I was told that one gets used to the bars so stuck with it. My lips burning was keeping me from sleeping, tongue sores, tongue bleeding, drooling, effort to swallow. My dentist told me that she has never heard of someone having a reaction to the bar before (come to find out it has nickel in it). We removed and it was instant relief. Over the next 24-48 hours my symptoms resolved completely. Since I did not have a lingual bar, I was told to wear my retainers. I waited a bit for my mouth to improve and have been diligently wearing them. I have developed sores on my tongue, tongue swelling and sharp stapling pain in the tongue that radiates to my throat, the tongue has a burn yet ache. My lips again swollen and painful. They feel like they are sunburned (they are not), I am constantly putting cortisone cream, Vaseline and taking Zyrtec but the hurt. In addition, I have been taking valtrex as initially I wasn’t sure I wouldn’t develop cold sores. I am again drooling. I noticed I have been feeling more short of breath to the point I felt I needed to have this evaluated before I go scuba diving to be sure I don’t have an event in water. Looking back while on Invisalign, I experienced more anxiety, i ended up in the ER once with GI symptom flare and once cardiac and under going echo and halter but now I wonder how much these things played into my last several months of not feeling well. The lip swelling, burning and pain as well as tongue symptoms, drooling and not sleeping for weeks to months due to pain is enough that I am done with this product. My dentist told me I am her only patient with any issues and that she is not aware of reaction to Invisalign. Clearly, I am not alone

• C.October 30, 2022 at 10:00 pm

  I used Invisalign for 7 days. It was day 7 when I realized my upset stomach, gas, bloating and nauseated feeling was associated with my new aligners. I went to the pharmacy on day 6 and picked Pepto and some other gas medicine which I have never needed before. Day 7 is when I let it go. I could not continue to get worse. Thank God, I have had to watch over my health closely in the past and notice[Show More]I used Invisalign for 7 days. It was day 7 when I realized my upset stomach, gas, bloating and nauseated feeling was associated with my new aligners. I went to the pharmacy on day 6 and picked Pepto and some other gas medicine which I have never needed before. Day 7 is when I let it go. I could not continue to get worse. Thank God, I have had to watch over my health closely in the past and notice changes and the association quickly. I wanted Invisalign for years, but it quickly did more harm than good.

• CynthiaOctober 30, 2022 at 4:01 am

  I’m on my 6th set of aligners and have been feeling like crap off and on for sometime now, not sure if it started right away with the aligners but I do feel that they might be making me sick. I decided to Google it tonight to see if anyone else experienced some of the same problems and I’m saddened to see so many others are suffering. I’m seeing my dentist on Monday and can’t wait to discuss this [Show More]I’m on my 6th set of aligners and have been feeling like crap off and on for sometime now, not sure if it started right away with the aligners but I do feel that they might be making me sick. I decided to Google it tonight to see if anyone else experienced some of the same problems and I’m saddened to see so many others are suffering. I’m seeing my dentist on Monday and can’t wait to discuss this with him. I’m hoping there is an alternative to the aligners I’m using. They really should make people aware of the possibility of negative side effects.

• KristenOctober 13, 2022 at 11:13 am

  I found this page after two months of searching for answers! I started Invisalign braces treatment on July 14, 2022. My allergic reaction to Invisalign braces began the week of August 8th, 2022 when I began my 4th pair of braces. My initial symptoms included an itchy scalp, scalp pressure, hair shedding, and general fatigue. As August continued, I had a general feeling of unwell, fatigue, scalp[Show More]I found this page after two months of searching for answers! I started Invisalign braces treatment on July 14, 2022. My allergic reaction to Invisalign braces began the week of August 8th, 2022 when I began my 4th pair of braces. My initial symptoms included an itchy scalp, scalp pressure, hair shedding, and general fatigue. As August continued, I had a general feeling of unwell, fatigue, scalp pressure, anxiety, and headaches. During this time, I went to monthly doctor’s appointments in August, September, and October. I had monthly dermatology appointments each month as well. All prescribed prescription shampoo and steroids to address my health concerns. I had lost 10lbs. I continued this treatment for 4-6 weeks with no improvement. We discontinued the treatment plan to see if the prescribed medication was causing irritation. There was no improvement with worsening symptoms. During late September, I was still experiencing general anxiety, feeling unwell, fatigue, scalp pressure, and headaches. During the first week of October, I had additional symptoms of difficulty sleeping and heart palpitations and my nerves felt entirely out of balance. On October 12, I took out my Invisalign and contacted my primary care physician, dentist, and dermatologist about this possible connection. All parties agreed to remove the Invisalign for a week to see if symptoms improve.

• hOctober 12, 2022 at 1:09 pm

  UPDATE !I ended up in ER last night again Tuesday October 10th again due to the reactions from the INVISALIGN TRAYS MATERIAL(chest pain & shortness of breath, swollen lymph nodes, swelling in jaw tissue , extremely painful lip swelling and blistering, my sitting heart rate was 141) due to the duration of exposure to the Invisalign toxins and the placement (i.e. in my mouth giving the toxins a d[Show More]UPDATE !I ended up in ER last night again Tuesday October 10th again due to the reactions from the INVISALIGN TRAYS MATERIAL(chest pain & shortness of breath, swollen lymph nodes, swelling in jaw tissue , extremely painful lip swelling and blistering, my sitting heart rate was 141) due to the duration of exposure to the Invisalign toxins and the placement (i.e. in my mouth giving the toxins a direct route to my whole body for SIX months) the ER doctor does not believe that this will be a quick recovery . This was also confirmed by ER Doctor on Saturday, October 8 which was my first visit to ER after discovering that my Invisalign trays were causing me a severe adverse reaction. I had full face swelling, blisters in the lips and tongue, swollen lymph node, difficulty breathing, heart palpitations, migraine, extreme fatigue, brain fog. The ER doctor prescribed me 50 mg of prednisone for inflammation and performed EKG, stressing if I had any continuing issues to go back to the ER immediately. I removed the Invisalign trays on Tuesday night October 5 when whole face swelled. Saw my dentist Wednesday, October 6. The swelling was bad but persisted to get worse within my actual mouth and lips and lymph nodes. I am on my fourth day of 50 mg prednisone and the swelling has started to recede but the blistering which is in my lips and inside my jaw tissue is persistent, and ER doctor said it could take weeks for this to subside due to the duration of exposure from the Invisalign trays, which has been six months, and he could not tell me when I may return back to normal. When I first put the Invisalign in, I started to experience headaches had some swelling, but it would come and go as the months went on. I started to experiencing migraines severe upon waking up, severe, chronic fatigue, severe joint pain severe brain fog I was sleeping 12 to 14 hours a day. It has totally disrupted my life. My doctor has categorically logged all of these issues because we have done blood test and allergy test to try and figure out what the problem was in the whole time. The problem was the Invisalign tray , I have done research and found hundreds and hundreds and hundreds of other documentations of experiences like mine or worse. The Invisalign client agreement does not disclose any of these severe reactions being a possibility my dentist was totally unaware of any of these adverse reactions being an issue, and on the website, they do not disclose any type of adverse reactions. Had I had the knowledge to know that these symptoms were caused by the Invisalign I could’ve ended my treatment much sooner and save myself months and months of pain and suffering. I understand that the FDA gave Invisalign online technology a warning in 2011 about non-disclosure and non-transparency of severe adverse reactions in their patients. I discovered many other documented case similar or worse than my own.

• HOctober 7, 2022 at 5:00 pm

  Thank god for this comment page! I am a healthy 49 year old. I Began Invisalign on April 4, 2022. They give you four trays at a time before you are seen by your dentist for the next batch of trays. During the first batch of trays. I've started to experience headaches, fatigue, mouth sores, and rashes. All of which are unusual for me, but did not connect it at the time. My second batch of trays [Show More]Thank god for this comment page! I am a healthy 49 year old. I Began Invisalign on April 4, 2022. They give you four trays at a time before you are seen by your dentist for the next batch of trays. During the first batch of trays. I've started to experience headaches, fatigue, mouth sores, and rashes. All of which are unusual for me, but did not connect it at the time. My second batch of trays my headaches became worse, and I started to experience joint pain, and my fatigue was becoming worse, and brain fog. I was also experiencing mouth ulcers, but again did not connect it to Invisalign - on my third batch of trays my fatigue was overwhelming and rashes began popping up all over my body. Swollen glands and throat. I had severe brain fog along with migraines. I also had intermittent tongue swelling, and mouth ulcers. On my fourth batch I only used the first tray, and my lips started to swell, along with mouth, and eyes. So switched to the new trays from the same batch and my face blew up I realize that the issues I have been experiencing were directly from the Invisalign. I immediately stopped them two days ago 10/05/2022. Although the swelling is receding, I have internal blisters in lips - like chemical burns. The doctor has prescribed Prednisone and Zyrtec so we will see what the long term ramifications are. I have been slowly poising myself for six months. Along with all the other issues I have been experiencing sever joint pain from the inflammation that is being cased from my reaction to the material used in the trays which are manufactured in MEXICO! Upon deciding to do INVISALIGN at no point was I ever advised that there were these potential adverse reactions. Invisalign has contacted me but I have no idea how this will proceed. I have paid $7700 for the comprehensive system out of pocket and completed half returning the fourth batch of trays to them. They offered a hypo-allergenic trays to finish the treatment, but from what I have read they are no better, not risking what's left of my health. And why wouldn't they use hypoallergenic tray for everyone??? I would advise caution when using this treatment, had i been informed I could have saved myself months of misery and probably long-term damage. I cannot believe there has not been a class action lawsuit.

• GeorgeSeptember 30, 2022 at 1:45 am

  I am an otherwise healthy 43 year old male that is currently on tray 1 of the 2nd set of my Invisalign treatment. I first noticed I had developed this extremely itchy skin condition mainly on hands, feet and thighs after wearing my Invisalign trays overnight during my previous treatment tray. I initially attributed the cause of this itchiness and hives to food, dust, laundry detergent and ever[Show More]I am an otherwise healthy 43 year old male that is currently on tray 1 of the 2nd set of my Invisalign treatment. I first noticed I had developed this extremely itchy skin condition mainly on hands, feet and thighs after wearing my Invisalign trays overnight during my previous treatment tray. I initially attributed the cause of this itchiness and hives to food, dust, laundry detergent and everything else one would consider a possible culprit, until I lost tray 7 awaiting my current set that the itchiness and hives went away and received my current tray which I wore overnight. To my disappointment , The hives and itchiness has returned with vengeance. I am experiencing very itchy hands, arms and legs as well as swollen lymph nodes And hives. I have also lost over 20Lbs during this time and I am very curious to see if anyone else has experienced similar symptoms.

• GeorgeSeptember 29, 2022 at 12:52 pm

  I am an otherwise healthy 43 year old male that is currently on tray 1 of the 2nd set of my Invisalign treatment. I first noticed I had developed this extremely itchy skin condition mainly on hands, feet and thighs after wearing my Invisalign trays overnight during my previous treatment tray. I initially contributed the cause of this itchiness and hives to food, dust, laundry detergent and eve[Show More]I am an otherwise healthy 43 year old male that is currently on tray 1 of the 2nd set of my Invisalign treatment. I first noticed I had developed this extremely itchy skin condition mainly on hands, feet and thighs after wearing my Invisalign trays overnight during my previous treatment tray. I initially contributed the cause of this itchiness and hives to food, dust, laundry detergent and everything else one would consider a possible culprit, until I lost tray 7 awaiting my current set that the itchiness and hives went away and received my current tray which I wore overnight. To my disappointment , The hives and itchiness has returned with vengeance. I am experiencing very itchy hands, arms and legs as well as swollen lymph nodes And hives. I have also lost over 20Lbs during this time and I am very curious to see if anyone else has experienced similar symptoms.

• lyssaSeptember 3, 2022 at 9:36 am

  started invisalign 3 years ago. Healthy female tri athlete of now 55 . started invisalign and had a few episodes of through tightening and a feeling of closing. expedited the time frame by skipping each tray so i only had to wear them 1/2 the time. i am now wearing the retainer every night by invisalign. I started having symptoms may 29th of 2019 with blisters on the bottom of my lips. it then pro[Show More]started invisalign 3 years ago. Healthy female tri athlete of now 55 . started invisalign and had a few episodes of through tightening and a feeling of closing. expedited the time frame by skipping each tray so i only had to wear them 1/2 the time. i am now wearing the retainer every night by invisalign. I started having symptoms may 29th of 2019 with blisters on the bottom of my lips. it then progressed to constant burning and then swelling and then a white scaly blistery like and either purple or deep red color lips. These symptoms are constant and every day of my life since may of 2019. i Have seen 8 specialists and been incorrectly diagnosed with lupus, RA, and an auto immune called phemfigus . i am now going to change my retainer to a wire and no more retainers. I think this may be my issue. I have had 2 biopsy's suggesting sun damage so i did cryo freezing on both lips. Swelling was better but now symptoms are coming back. Most importantly i asked my dentist who gave me the invisalign if i may be allergic. He said he gave me the hypoallergenic ones. When visiting with the representative of invisalign one day in the dentist office back in 2019 i had said how grateful i was to have an hypoallergenic one he relied " I dont know what your talking about, we do not make a hypoallergenic one." SCAM!

• ScottAugust 31, 2022 at 5:34 pm

  Some info for anyone with a previous autoimmune disorder. At the age of 61 decided to go with Invisalign program for teeth straightening. I've been struggling with a diagnosis of Rheumatoid Arthritis for over 20 years and have been able to keep my RA factor hovering around 30-40 with diet, exercise and other self help techniques. 3 years into Invisalign treatment my RA factor had jumped over 4 [Show More]Some info for anyone with a previous autoimmune disorder. At the age of 61 decided to go with Invisalign program for teeth straightening. I've been struggling with a diagnosis of Rheumatoid Arthritis for over 20 years and have been able to keep my RA factor hovering around 30-40 with diet, exercise and other self help techniques. 3 years into Invisalign treatment my RA factor had jumped over 4 fold and I'm starting to experience severe brain fog, extreme low energy, worse joint pain/inflammation and lately dizzy spells. I'm one tray away from finishing my last "refinement" and plan on stopping completely in about 2 weeks. Total time with program about two and a half years. I will finish, if needed, with traditional braces. Interesting that I did a digestive/stool analyses where secretory IgA was high in digestive track but subsequent food allergy test was negative to all foods tested. Something is causing a immune response in the GI tract (as well as elsewhere) but not food, hummm wonder what that might be...........

• SteffanyAugust 14, 2022 at 7:07 am

  When I started Invisalign prior to the pandemic, I experienced swollen gums, burning lips, and gum irritation and recession. My orthodontist advised that he had never heard of these problems and acted as though I was making bizarre statements.. I tried to restart after a break and experienced the same symptoms but also with an added sore throat. Invisalign and dentists clearly have invested a l[Show More]When I started Invisalign prior to the pandemic, I experienced swollen gums, burning lips, and gum irritation and recession. My orthodontist advised that he had never heard of these problems and acted as though I was making bizarre statements.. I tried to restart after a break and experienced the same symptoms but also with an added sore throat. Invisalign and dentists clearly have invested a lot of money into this endeavor and have reaped profits. They are not being upfront about side effects. This needs to be investigated. As soon as I stopped Invisalign, my gum inflammation, lip and tongue burning, gum recession and sore throat disappeared. There’s some interaction with the plastic causing an immune response that is concerning. I’m out $5,000.

• QueenAugust 4, 2022 at 8:55 pm

  God has Answered my prayers To Lead me to this Group. All of this just hit me today. I just started/stopped my 8th tray. Besides my normal anxiety I have I truly felt out of my mind on Tray 3 I kept feeling THE DECREASE in my Energy and I kind of shrug it off thinking I just needed more B 12. Another week passes another tray still feeling the same. But a few days later I started feeling sick sick[Show More]God has Answered my prayers To Lead me to this Group. All of this just hit me today. I just started/stopped my 8th tray. Besides my normal anxiety I have I truly felt out of my mind on Tray 3 I kept feeling THE DECREASE in my Energy and I kind of shrug it off thinking I just needed more B 12. Another week passes another tray still feeling the same. But a few days later I started feeling sick sick to my stomach and thought it was my IBS but this episode feels more intense and my meds stopped working (never happens). The Red Flags are coming so I’m just drinking smoothies and a few nights I use to dose off and forget to put back in and then I would feel a lil okay but kept wearing. I made a gastroenterologist appointment had ultrasounds done on my kidney, gallbladder, and liver to rule out and infection because I’m am not Myself at all physically and mentally because I feeling fatigued everyday at this point. Oh also had bloodwork done as well. I woke up at 4 am this morning and my mind is going I’m praying for some guidance and now I’m here sooo relieved but so Sorry that we are experiencing these reactions to these aligners. I’m working an alternative route and will keep you posted. I am no longer wearing those trays and can’t wait to be back at 100%

• RaquelJuly 24, 2022 at 9:16 am

  Ever since I started Invisalign in 2019 I felt physically off. I developed an episode of tinnitus soon after. I also developed blurry vision and severe eczema on my hands. Shortly after I started the Invisaligners I noticed extreme changes in my menstrual cycle and my docs confirmed a uterine polyp which required surgery. When I asked the orthodontist if there was a possible connection between m[Show More]Ever since I started Invisalign in 2019 I felt physically off. I developed an episode of tinnitus soon after. I also developed blurry vision and severe eczema on my hands. Shortly after I started the Invisaligners I noticed extreme changes in my menstrual cycle and my docs confirmed a uterine polyp which required surgery. When I asked the orthodontist if there was a possible connection between my symptoms and the plastic chemicals in the aligners he denied it. He did however order a hypoallergenic version of the trays and my eczema improved slightly, but did not go away until I finished the treatment. I am now wearing retainers at night but still have symptoms such as blurry vision and a puffy face. I believe these aligners are toxic for the body..

• JenniferJuly 21, 2022 at 9:18 pm

  I started Invisalign 4 days ago and have been nauseous and horrible headache since. When I take them out to eat I start to feel better. Then once I put them back in the nausea starts up . Was never given Any potential side effects. Concerned on losing alot of money but don’t want to end up in the hospital because no one was honest about the side effects.

• MS_FloridaJuly 11, 2022 at 9:57 pm

  I completed my Invisalign in January 2022. In February 2022, I started experiencing numbness/soreness along the left side of my tongue and down the left side of my throat. I also have a swollen lymph node below the left side of my jaw. I have seen all kinds of doctors and no one has been able to help. After reading all these comments, I am now suspecting that all this may be caused by the Invisali[Show More]I completed my Invisalign in January 2022. In February 2022, I started experiencing numbness/soreness along the left side of my tongue and down the left side of my throat. I also have a swollen lymph node below the left side of my jaw. I have seen all kinds of doctors and no one has been able to help. After reading all these comments, I am now suspecting that all this may be caused by the Invisalign retainer I wear at night! My symptoms go away when I do not wear it, which may be an indicator that it is the root of the problem.

• matthewJune 27, 2022 at 6:12 pm

  I used mouthwash to rinse and clean my invisaligns and never knew it could ruin my digestive system. there are no warnings on their website that I found. Anyone with Invisalign retainers on who uses mouthwash before bed is slowly poisoning themselves. I realized I had a problem after 3 days in the hospital and a quarter size blister in my mouth.

• AnnieJune 21, 2022 at 11:50 pm

  I am on set 19 and I have developed an issue swallowing. After reading all these comments I now see its probably the invisalign.

• MaryJune 13, 2022 at 10:27 pm

  I had a bad reaction within several days of using Invisalign and admitted to ER with feeling of throat closing, at 58 yrs old no prior history with allergies. I do not recall being informed of this risk and am discontinuing the product .

• MaryJune 13, 2022 at 1:54 pm

  I had a bad reaction within several days of using Invisalign and admitted to ER with feeling of throat closing, at 58 yrs old no prior history with allergies. I do not recall being informed of this risk and am discontinuing the product .

• WillyJune 7, 2022 at 6:17 pm

  So glad I found this thread, woke up yesterday with what I can only explain as an extremely sore tongue all the way around the edges where it touches the Invisalign with swelling and a purplish/red bruising toward the front. I tried thinking back on anything I ate that could have caused this but I’ve never been allergic to any foods let alone any I had consumed recently. Only change is me starting[Show More]So glad I found this thread, woke up yesterday with what I can only explain as an extremely sore tongue all the way around the edges where it touches the Invisalign with swelling and a purplish/red bruising toward the front. I tried thinking back on anything I ate that could have caused this but I’ve never been allergic to any foods let alone any I had consumed recently. Only change is me starting Invisalign roughly 6 days ago. I called my dentist today and she said there are very few people who may have a reaction to Invisalign but to come in and have her take a look. I’m hoping this is the case and I can just stop using them and it will go away. Not sure if I can add comments to this one, but will follow up after if I am able.

• DeannaJune 5, 2022 at 5:42 pm

  I developed a serious rash around my mouth then eyes which urned into eczema flares and spread to my hands afermore months. I had considered whether my braces were a factor because of the timing of it. I asked my dentist and we both thought they were likely not connected. I feel strongly this may be the cause of my ongoing severe facial rash as I have had it as long as I have had the braces. Seen [Show More]I developed a serious rash around my mouth then eyes which urned into eczema flares and spread to my hands afermore months. I had considered whether my braces were a factor because of the timing of it. I asked my dentist and we both thought they were likely not connected. I feel strongly this may be the cause of my ongoing severe facial rash as I have had it as long as I have had the braces. Seen many heath professionals with no results.

• TerryJune 1, 2022 at 5:50 am

  Very similar to others commenting on Invisalign, a few trays into my treatments I got what I thought was a cold, followed by a sore throat and then extreme shortness of breath. Then came an ER visit, the Doctor tried antibiotics, I seemed better, short time later another ER visit, I was tested for Covid - negative, chest x-ray, everything appeared normal. The Doctor/Pharmacist gave me a bag full [Show More]Very similar to others commenting on Invisalign, a few trays into my treatments I got what I thought was a cold, followed by a sore throat and then extreme shortness of breath. Then came an ER visit, the Doctor tried antibiotics, I seemed better, short time later another ER visit, I was tested for Covid - negative, chest x-ray, everything appeared normal. The Doctor/Pharmacist gave me a bag full of allergy medicine, soon after I'm back in the ER again. This time I told the Doctor about the Invisalign trays- she said take them out now! Breathing back to normal, no seasonal allergies, it was the Invisalign trays.

• JessicaMay 30, 2022 at 6:05 pm

  Since wearing Invisalign in October 2020, I began getting red, swollen sore throats straight away, and routinely, after changing new trays. It went on for months and I’d brought this up to my orthodontist from the beginning, who found it hard to believe. Going forward, I washed all my new trays very thoroughly before putting them in to try and help.. it did a little. I am now in my final tray[Show More]Since wearing Invisalign in October 2020, I began getting red, swollen sore throats straight away, and routinely, after changing new trays. It went on for months and I’d brought this up to my orthodontist from the beginning, who found it hard to believe. Going forward, I washed all my new trays very thoroughly before putting them in to try and help.. it did a little. I am now in my final trays, and in a full blown mouth infection for 10 days, likely cause: Invisalign. I went to the walk in and then emerg a few days later. I haven’t been able to drink water or eat. I have been sucking on unlimited ice cubes for comfort. My mouth went from feeling like sharp glass all down my throat, to white patches and raw sores, to needing a steroid shot to get the inflammation down in my mouth, since pain relievers did nothing. So incredibly upset my concerns were never taken seriously, and it had to get to this point. I’m disappointed to see so many others with the same issues and the product has not been reviewed.

• JessicaMay 30, 2022 at 4:46 pm

  Since wearing Invisalign in October 2020, I began getting red, swollen sore throats straight away, and routinely, after changing new trays. It went on for months and I’d brought this up to my orthodontist from the beginning, who found it hard to believe. Going forward, I washed all my new trays very thoroughly before putting them in to try and help.. it did a little. I am now in my final tray[Show More]Since wearing Invisalign in October 2020, I began getting red, swollen sore throats straight away, and routinely, after changing new trays. It went on for months and I’d brought this up to my orthodontist from the beginning, who found it hard to believe. Going forward, I washed all my new trays very thoroughly before putting them in to try and help.. it did a little. I am now in my final trays, and in a full blown mouth infection for 10 days, likely cause: Invisalign. I went to the walk in and then emerg a few days later. I haven’t been able to drink water or eat. I have been sucking on unlimited ice cubes for comfort. My mouth went from feeling like sharp glass all down my throat, to white patches and raw sores, to needing a steroid shot to get the inflammation down in my mouth, since pain relievers did nothing. So incredibly upset my concerns were never taken seriously, and it had to get to this point. I’m disappointed to see so many others with the same issues and the product has not been reviewed.

• JustMay 29, 2022 at 1:10 pm

  I have had the Invisaligns in for about 6 months. Around three months I started to have what felt like onset of a sore throat.. Then the severe jaw popping , which my ortho said it wasn’t anything. My sore throat turned into this weird sensation like if I had smoke in my mouth that made me want to cough. Then it went to a weird feeling into my throat and upper chest. I went in for another round [Show More]I have had the Invisaligns in for about 6 months. Around three months I started to have what felt like onset of a sore throat.. Then the severe jaw popping , which my ortho said it wasn’t anything. My sore throat turned into this weird sensation like if I had smoke in my mouth that made me want to cough. Then it went to a weird feeling into my throat and upper chest. I went in for another round of try’s last week and told my ortho about it. She prescribed antibiotics. Went home, was woken up with this throbbing pain in front of ear. When to touch it and my lymph nosed had swelled up like water balloons. I immediately took out the liners and went to ER. Had a CAT scan , nothing, had blood work to rule out high white cell count, negative. Called my Ortho, she don’t believe it’s TMD, will see in a few weeks with ENT. Still have this weird sensation on tongue in throat…

• SandyMay 17, 2022 at 2:09 pm

  Wow, I am relieved to read I'm not alone. I woke up this morning with another sore throat and it came to me that maybe it's the invisalign causing my issues. Sure enough I found this page when I began searching online. My orthodontist was terrible from the start, I should have been alarmed with the multiple page form I was made to sign waiving the orthodontist of liabilities. Although at no t[Show More]Wow, I am relieved to read I'm not alone. I woke up this morning with another sore throat and it came to me that maybe it's the invisalign causing my issues. Sure enough I found this page when I began searching online. My orthodontist was terrible from the start, I should have been alarmed with the multiple page form I was made to sign waiving the orthodontist of liabilities. Although at no time was I told Invisalign could be unsafe. I had mouth sores from the beginning of treatment which I told my orthodontist were worse than the metal braces I had when I was younger. I had many of the attachments removed as I had constant sores in my mouth. Over the course of treatment I experienced and continue to experience severe fatigue, headaches, brain fog, dry mouth/lips, sore throat, abdominal discomfort and bloating, swelling around eyes, blurry vision, waking up feeling anxious, dehydration, and insomnia. This has persisted for more than two years. I have been to numerous doctors, some who run rests but mostly dismiss it. I finished the trays a year ago, however I still wear the nightly retainer. I will stop that immediately as I'm pretty convinced it is the cause of my suffering. What I'm curious about is if anyone is reporting these issues to Invisalign or to the FDA themselves. I am going to today.

• BreoshaMay 16, 2022 at 9:51 pm

  I’m having lots of similar symptoms that everyone on here has experienced. My throat is very sore to the touch on the outside and raw internally. I can barley swallow food without pain and discomfort! I got a steroid shot in my leg to help calm down the swelling and it helped but as soon as I ate spaghetti last night, my throat burned so bad with every swallow. I’m back to square one again. Nobody[Show More]I’m having lots of similar symptoms that everyone on here has experienced. My throat is very sore to the touch on the outside and raw internally. I can barley swallow food without pain and discomfort! I got a steroid shot in my leg to help calm down the swelling and it helped but as soon as I ate spaghetti last night, my throat burned so bad with every swallow. I’m back to square one again. Nobody is being of any help! Can someone tell me what they’ve found out?

• ELIZABETHMay 16, 2022 at 3:40 pm

  I have barely started my 2nd tray out of 45. My tongue swells up and has white bumps around the edges of it. My tongue is sensitive and painful. I get blisters on the inside of my lips which are dry and cracking. It is actually challenging to speak because my throat is so sore and my tongue is swollen making difficult to swallow. I have a slight burning sensation in the back of my throat. I have h[Show More]I have barely started my 2nd tray out of 45. My tongue swells up and has white bumps around the edges of it. My tongue is sensitive and painful. I get blisters on the inside of my lips which are dry and cracking. It is actually challenging to speak because my throat is so sore and my tongue is swollen making difficult to swallow. I have a slight burning sensation in the back of my throat. I have had an usual taste in my mouth which is difficult to describe but might be something along the lines of what it would taste like to suck on a musty towel. The taste just lingers constantly even after brushing my teeth and tongue. At night my mouth gets severely dry but when I take a drink of water I can barely manage to swallow it. I have been taking Benadryl and have had minor relief. I am hoping that these symptoms subside now that I have stopped using the Invisalign. At this point, symptoms are still occurring. Initially I thought that I must have been having a reaction to food. However, this morning I decided that I would fast for 24 hours to give my system a break and narrow down what might be causing it. I did not eat today and have only had water yet am still experiencing the issues. At this point, I have finallyrealized that it must be related to the invisalign. I have never had this issue prior to using invisalign. I am grateful for this site as I can see via the comments that others have had similar experiences which reconfirms my suspicions of Invisalign being the culprit. I have adhered to protocol for Invisalign care. I take out my trays when eating or drinking anything other than water. I brush my teeth after eating and prior to reinserting the trays. I clean the trays with warm water and the soft bristle toothbrush provided by the orthodontist office. These symptoms started fairly early on it just took me a couple of weeks to pinpoint what was causing the issue. I have called my Orthodontist and left a voice message but have yet to hear back from the office. I have paid over $3000 and am hoping that they will allow me to switch to braces or just refund my money.

• PauletteApril 26, 2022 at 1:42 pm

  After reading the comments posted on this page, I too have had an adverse reaction to Invisalign. I started treatment in January 2022. Since that time I have deveIoped mouth sores and swollen lingual papilla . After several visits to my PCP, dentist and Urgent care , no-one could explain what was causing these symptoms. It was only after I experiencing a severe reaction last week that I realized [Show More]After reading the comments posted on this page, I too have had an adverse reaction to Invisalign. I started treatment in January 2022. Since that time I have deveIoped mouth sores and swollen lingual papilla . After several visits to my PCP, dentist and Urgent care , no-one could explain what was causing these symptoms. It was only after I experiencing a severe reaction last week that I realized I was experiencing an allergic reaction to Invisalign . After wearing Invisalign for 8 hours, I experienced severe mouth burning, tingling and difficulty swallowing and lip swelling. I am a RN and I knew I was having an allergic reaction to the Invisalign. I immediately took Benadryl. I saw my orthodontist today and insisted that the buttons be removed and my treatment stopped. After what I experienced last week ,I would not attempt placing these devices in my mouth out of fear that the next reaction could be more serious. I am still experiencing mouth burning and lip swelling and it is four days since I removed the trays. Unfortunately, my orthodontist will not refund my money. There needs to be warnings placed on this medical device. Before starting treatment with Invisalign, people should be made aware of possible side effects.

• TheresaApril 25, 2022 at 9:46 am

  I wore Invisalign for 7 months. During the entire treatment, my tongue has a burning/numbness sensation and my sense of taste was greatly impaired. My mouth was constantly irritated. Even though, my sense of taste was nearly destroyed, there were times that my mouth felt/tasted like an ash tray. I have not other description for it. My orthodontist did not take my concerns seriously. I am now weari[Show More]I wore Invisalign for 7 months. During the entire treatment, my tongue has a burning/numbness sensation and my sense of taste was greatly impaired. My mouth was constantly irritated. Even though, my sense of taste was nearly destroyed, there were times that my mouth felt/tasted like an ash tray. I have not other description for it. My orthodontist did not take my concerns seriously. I am now wearing the retainers and am having the same issue--even worse. I am switching to a traditional retainer with the hope that my tongue and mouth will heal. I would never have elected to use Invisalign if I knew of these possible side effects.

• PauletteApril 22, 2022 at 7:42 pm

  I started Invisalign in January. 6 weeks into treatment I woke up with a circular white patch ulcer in the center of my tongue. I also felt like there was cotton in my mouth. On my next visit to the orthodontist, I showed him it and he informed me that if it didn’t clear I would need an antibiotic. I am a Registered Nurse and I felt it was candida. I tried everything over the counter to get rid [Show More]I started Invisalign in January. 6 weeks into treatment I woke up with a circular white patch ulcer in the center of my tongue. I also felt like there was cotton in my mouth. On my next visit to the orthodontist, I showed him it and he informed me that if it didn’t clear I would need an antibiotic. I am a Registered Nurse and I felt it was candida. I tried everything over the counter to get rid of it unsuccessful. I saw my family physician and she thought it may be secondary to acid reflux. I was started on Prilosec but it did not clear. It got progressively worse and I was seen in urgent care where I was diagnosed with thrush. I completed 14 days on an anti fugal medication. It cleared the infection but I developed enlarged bumps on the side of my tongue and on top of my tongue. I consulted my dentist but he was not sure why these bumps were swollen he felt they were lingual papillae. They are so large you can see them on my tongue. I also feel them when I swallow. The raised red bumps are just where my tongue comes in contact with the Invisalign. I have been taking Benadryl with some relief. I also have tongue burning. After reading these comments, I am sure I am also experiencing an adverse reaction to Invisalign. When I committed to Invisalign, I was never informed of possible side effects.

• ElyApril 20, 2022 at 8:43 am

  Female 38 y.o. I've started Invisalign last January. I did not have any problems until the 4th mask. After three days of wearing it I started to feel strange pressures in my head and chest, an incredible and never felt before weakness. I went to the ER thinking I was having a heart attack or stroke. In the meantime I was frantic , my nervous system was out of control. All the tests were Ok. For a[Show More]Female 38 y.o. I've started Invisalign last January. I did not have any problems until the 4th mask. After three days of wearing it I started to feel strange pressures in my head and chest, an incredible and never felt before weakness. I went to the ER thinking I was having a heart attack or stroke. In the meantime I was frantic , my nervous system was out of control. All the tests were Ok. For a week I was bedridden, I took off Invisalign but initially had no connection. When I felt better I started the treatment again, but a week after the mask change I was sick again. Panic attacks at night, chest pains, digestive difficulties, visits, doctors, worry. Now I haven't worn it for a month, but I still have some after-effects, such as reflux that doesn't let me sleep, problems with my neck. Reading your testimonies made me feel less crazy, I didn't know what to think anymore. There should be more awareness about these possible reactions.

• PeggyApril 16, 2022 at 9:43 am

  2 weeks after taking out the Invisalign braces (used them for 3 weeks) I still have watery bowl movements, extreme bloating, pain in my intestines and liver and kidneys and going for an ultrasound of abdomen. Had blood work done, don't know yet but urinalysis shows blood and protein in urine, meaning an infection is present. I am so sick, diarrhea for 5 weeks. I have tried everything I can think o[Show More]2 weeks after taking out the Invisalign braces (used them for 3 weeks) I still have watery bowl movements, extreme bloating, pain in my intestines and liver and kidneys and going for an ultrasound of abdomen. Had blood work done, don't know yet but urinalysis shows blood and protein in urine, meaning an infection is present. I am so sick, diarrhea for 5 weeks. I have tried everything I can think of including not eating. I Sure hope my doctor will help me I feel like I'm dying. Absolutely no energy! I have a severe allergy to plastic. I knew I had a plastic allergy on my skin because plastic tubing caused me to have bloody welts after a surgery. I had no idea that it would hurt me so much internally! Where were the warnings?

• LisaApril 9, 2022 at 6:56 am

  Are you all also using mouthwash Mouthwashes often have a quaternary ammonia ingredient which can also be an allergen that causes these symptoms I see a few that post symptoms continue after disuse. Consider that...

• matthewMarch 30, 2022 at 5:07 pm

  I have had stomach for the last seven months. Acid re-flux at night waking me up and in the last 6 weeks having to run to the bathroom with diarrhea. I also had problems swallowing. When I finally got a blister inside my mouth the size of a quarter last week I started doing my own research because the five doctors I had seen had not helped me at all and was loosing a scary amount of weight. Tha[Show More]I have had stomach for the last seven months. Acid re-flux at night waking me up and in the last 6 weeks having to run to the bathroom with diarrhea. I also had problems swallowing. When I finally got a blister inside my mouth the size of a quarter last week I started doing my own research because the five doctors I had seen had not helped me at all and was loosing a scary amount of weight. That is when I saw the post about these Invisalign retainers causing these symptoms and figured out what was happening to me. I am posting these symptoms to alert others reading this site, but the doctors really need to be aware of this, especially the gastroenterologist doctors. I ended up in the hospital on an IV and if I had not figured this out on my own who knows how bad it could have gotten.

• MichaelMarch 29, 2022 at 10:13 pm

  62 year old male. According to the ortho DDS, 12-15 months. I am on month 12, third set of aligners, totaling 34 worn. Teeth hurt, canines won’t move, and my jaw pain is brutal. A couple teeth refuse to move. In the past 2 months I am having a reaction to the aligners with stomach and general nerve issues. I am seriously considering switch to metal to get this scam off my teeth. Invisalign Plat[Show More]62 year old male. According to the ortho DDS, 12-15 months. I am on month 12, third set of aligners, totaling 34 worn. Teeth hurt, canines won’t move, and my jaw pain is brutal. A couple teeth refuse to move. In the past 2 months I am having a reaction to the aligners with stomach and general nerve issues. I am seriously considering switch to metal to get this scam off my teeth. Invisalign Platinum provider. Terrible experience.

• MariaFebruary 16, 2022 at 10:47 am

  Was sold Invisalign through an advertisement but the dr delivered an off brand and won’t return my money.

• YolandaFebruary 15, 2022 at 6:57 pm

  Comenze en octubre 6 2021 a utilizar los invisaling y a los 2 meses comencé a sentir boca super salada dolor d oídos y una presión en la cabeza algo fuera d lo normal.Deje d usarlos y fui a otro dentista para q me removieron los sujetadores. Desde ese momento comenzó a mejorar mi boca y mi salud

• WilmaFebruary 13, 2022 at 9:53 am

  I finished my Invisalign treatment back in March 2021 but didn’t actually attributed my symptoms and discomfort to the Invisaligns until October 2021. During treatment I felt discomfort in my Jaw, what it felt like sore and/or swollen tongue and tingling in my tongue, but I thought it was normal due to movement of teeth. Once I started the Vivera retainer, my symptoms became more acute and started[Show More]I finished my Invisalign treatment back in March 2021 but didn’t actually attributed my symptoms and discomfort to the Invisaligns until October 2021. During treatment I felt discomfort in my Jaw, what it felt like sore and/or swollen tongue and tingling in my tongue, but I thought it was normal due to movement of teeth. Once I started the Vivera retainer, my symptoms became more acute and started to see the blister in my mouth and experiencing nausea. It is February 2022 and I am still dealing with this horrible symptoms. Just a few weeks ago, I had a abdominal episode that after doing test and CT scan, I am starting to suspect that it could be related to the adverse reaction on my mouth. Like everyone else here, my dentist doesn’t feel my issues are related to the Invisalign product; however, my primary care physician can no longer ignore the facts and is helping me research. Next I am going to a specialist to test all the Invisalign materials to confirm if indeed I am allergic to any of the components. I hope to find answers soon since this has been a hard couple of months with these unbearable symptoms. I wish there was a support group where we could share experiences and bring awareness.

• CassandraFebruary 10, 2022 at 2:14 pm

  On aligner 20 of 39 and have been experiencing general discomfort (despite effective teeth movement results) since the very first aligner. As of aligner 19, I began developing a swollen uvula with sore throat, this was after having experienced dry/cracked/irritated corners of my mouth for several weeks in a row. Sore tip of my tongue (the part that touches the edge of the aligner behind my front t[Show More]On aligner 20 of 39 and have been experiencing general discomfort (despite effective teeth movement results) since the very first aligner. As of aligner 19, I began developing a swollen uvula with sore throat, this was after having experienced dry/cracked/irritated corners of my mouth for several weeks in a row. Sore tip of my tongue (the part that touches the edge of the aligner behind my front teeth). I took a PCR test to rule out covid-19 which came back negative, the swollen uvula and throat soreness seemed to subside through the first week, however, after wearing a new aligner the following week it took just a few days before my uvula was once again swollen and throat became very dry/itchy/sore again as well. It's painful to swallow. I thoroughly clean my aligners day and night as well as my own teeth, using antibacterial mouth wash and following all of the precautions like avoiding wearing the aligners when eating/drinking and taking care not to expose the aligners to things that would degrade its composition. Any more effort than this would be unreasonable, but if that was truly necessary the orthodontist should clearly indicate the risks of not doing so. After following all of the precautions and taking the necessary care, it is clear that these symptoms are related to either the material of the aligner, its coating or perhaps saliva issues introduced by wearing the aligners. It is incredible that a doctor would recommend this product knowing the potential health risks associated with it. It's inhuman to put a product like this in a person's mouth and cause them to have to endure discomfort, mouth trauma, pain and health detriment for an extended period of time. I was always skeptical of wearing plastic in my mouth, but I did place my trust in the knowledge of my orthodontist and the reputation of this product, however, I feel I should have trusted my original instinct and avoided these like all hell.

• TraceyFebruary 5, 2022 at 8:54 pm

  My daughter has turned jaundice, had swollen glands and pain in her mouth. The orthodontist said it was something else but right now we are getting rid of the Invisalign retainer to gargling and taking antibiotics to get rid of her swelling.

• MemeJanuary 23, 2022 at 4:59 pm

  I'm a 62 years young woman, healthy, non smoker, non drinker, on my 14th tray of 30. I began having an allergic reactions but equated them to having (long) covid last year. When the palpitations began almost constantly along with episodes of elevated blood pressure I began to be concern. I could not sleep at night due to sweating, and waking in a panicked state. My mouth was dry and the corner[Show More]I'm a 62 years young woman, healthy, non smoker, non drinker, on my 14th tray of 30. I began having an allergic reactions but equated them to having (long) covid last year. When the palpitations began almost constantly along with episodes of elevated blood pressure I began to be concern. I could not sleep at night due to sweating, and waking in a panicked state. My mouth was dry and the corners of my mouth were cracked. I prayed for answers because I was feeling like this could lead to a heart attack with the tightness in my chest and palpation getting worst. Fate caused me to not wear my invisaligns for one day. I actually forgot to put them on. I began to feel better, the palpitations subsided by at least 30%. I then searched for possible allergic reactions reported by other invisalign users and I arrived here! Thank you so much for posting because I felt so isolated and that maybe this was just in my head.

• LauraJanuary 23, 2022 at 12:35 am

  A few weeks after I started wearing my aligners I had a burning/tingling sensation on the roof of my mouth, tong and gums and was told it was sensitivity. A few months later, I stopped Invisalign altogether and continued feeling the symptoms ever since. 6 months and my teeth have shifted (and still loose) and the symptoms persist. The only relief I get is when I’m eating or drinking. This is tort[Show More]A few weeks after I started wearing my aligners I had a burning/tingling sensation on the roof of my mouth, tong and gums and was told it was sensitivity. A few months later, I stopped Invisalign altogether and continued feeling the symptoms ever since. 6 months and my teeth have shifted (and still loose) and the symptoms persist. The only relief I get is when I’m eating or drinking. This is torture.

• RosemaryJanuary 14, 2022 at 2:23 pm

  I just returned from a visit to my doctor due to the fact that the entire inside of my mouth is swollen, my lips are dry to the point where not one product I have tried, can heal them. To the point where I am developing a red painful area from my lower lip down my chin. Red, dry, itchy, and very painful when it gets wet. I am dreading having to wear these invisalign trays for 8 hours every night[Show More]I just returned from a visit to my doctor due to the fact that the entire inside of my mouth is swollen, my lips are dry to the point where not one product I have tried, can heal them. To the point where I am developing a red painful area from my lower lip down my chin. Red, dry, itchy, and very painful when it gets wet. I am dreading having to wear these invisalign trays for 8 hours every night for the rest of my life. I can only taste some foods and, sure, I have lost weight, because I can't taste most foods. Eating a fine meal would be wasted on me. I eat because I need nutrition, and wouldn't if I didn't need to to live. The inside of my entire mouth and my lips are dry, swollen, and irritated. I can't continue to use the trays if this is how I will be, for the rest of my life. It's almost impossible to explain to my doctor. I literally can feel the 'folding' of the tissue inside my mouth when I purse my lips. It's horrible.

• HollyDecember 9, 2021 at 7:22 pm

  It’s nice to see other peoples experiences that are similar and know that I’m not crazy even though I have felt crazy for the last 6 months. The first 2 weeks that I started Invisalign my mouth was really itchy. I mentioned the itching to my orthodontist 3 days in and said that I hope I’m not allergic to them. She said that she had never heard of anyone being allergic, but to keep her posted. Sh[Show More]It’s nice to see other peoples experiences that are similar and know that I’m not crazy even though I have felt crazy for the last 6 months. The first 2 weeks that I started Invisalign my mouth was really itchy. I mentioned the itching to my orthodontist 3 days in and said that I hope I’m not allergic to them. She said that she had never heard of anyone being allergic, but to keep her posted. She didn’t seem concerned or to really take it seriously. I kept wearing them and after a few weeks the itching went away. Fast forward to August, 3 months later. I start feeling like I maybe I’m developing allergy’s like hay fever or something. My nose is runny and I’m sneezing, but I’m not sick. Then I start feeling like I can’t breath, like someone is sitting on my chest and my breathing is restricted. My belly out of nowhere, overnight got bloated (August 22-Nov.)and stayed bloated everyday. I have notice for months that I am really anxious, for seemingly no reason. I don’t feel like myself. I don’t feel comfortable in my own skin. I have felt anxiety and depression that I have never experienced my whole life. & my PMS has been worse and worse each month. I went to two different doctors trying to figure out what was going on with me. I did not attribute any of this to Invisalign until my husband realized one day that maybe I was having an allergic reaction to them. That all of these issues occurred after using Invisalign for a few months. I was on aligner #25 when I decided to make an appointment with an allergist. And on that same day I decided to take my aligners out. For the first time in months I slept without them in. The next day I could already feel somewhat of a difference. I was not instantly all better, but I could tell a reduction in some of my symptoms. It has now been 21 days since taking them out and I would say I’m probably 30% better. I’m still not back to normal. I had my allergist appointment today. He had me do a breathing test. He said my lungs are strong and should recover. It was really hard to breath into that tube. I could tell just doing the breathing test, that I don’t have my full lung capacity. He gave me an inhaler with prednisone to take everyday for 14 days. He said I should feel a little better each day and hopefully will be back to normal after the 14 days, but that some of the respiratory problems may come back. He said he could do some skin tests using the Invisalign plastic, but that I probably wouldn’t want to continue wearing them even if the test was negative, so it may not make sense to do those tests. I agree. I can feel the difference since taking them out, so it’s pretty obvious that they are the cause. The prednisone inhaler seemed like it helped me somewhat. I started to feel like I was about 50% better. Some days it wasn’t hard to breath anymore, but than some days still were difficult. I went to see my regular dentist(not my orthodontist) although he is also an orthodontist and works with Invisalign as well. I told him about what happened, that I was having breathing issues from my Invisalign trays and that I have felt somewhat better since taking them out. That I have not been given a refund yet, but was told that I could get a partial refund. During my appointment he took care of getting my attachments off. He said that they could be effecting me as well, causing some of the allergy. He also said that after they are off, I will probably feel worse again due to how the attachments come off. They use a super cold tool which causes the attachments to become a white powder that gets all over. They were careful to have me wash my mouth several times during the process to try to eliminate it getting in my system, but of course there’s really no stopping it. Sure enough, after I got home I felt sick. It was hard to breath and I felt weak. I rested the rest of the day. The next day I still had a hard time breathing but felt somewhat better. Today, is really hard to breath. It seems I have sent myself backwards getting the attachments off, but it was definitely necessary to get them out of my mouth. I don’t know if I will need about her round of prednisone to help me start to get better again or what I should do.

• KristaNovember 18, 2021 at 4:04 pm

  I was a victim of invisilign. Since taking it out my symptoms have gotten better however I’m still not back to the thriving person/athlete I was before. I went from a thriving athlete in the best shape of my life before Invisalign then to barely being able to function as a normal human being because of my symptoms. I was actually issued an RN at work bc of my symptoms. I was unable to swallow sol[Show More]I was a victim of invisilign. Since taking it out my symptoms have gotten better however I’m still not back to the thriving person/athlete I was before. I went from a thriving athlete in the best shape of my life before Invisalign then to barely being able to function as a normal human being because of my symptoms. I was actually issued an RN at work bc of my symptoms. I was unable to swallow solid food for a year, acid reflux, my throat often felt like it was closing ,brain fog, bloating, anxiety and elevated heart rate. It’s a long story but I want to share my symptoms and a glimpse of what I went through on here in case it helps anyone.

• HollyNovember 10, 2021 at 3:16 pm

  Hello! I'm wondering if there is any place where pictures are shared? I don't have a lot of symptoms that most of you have, however the inside of my lips, and now the front of my lips, are covered in what I would describe as blisters. It started about a month ago on the inside, cleared up, and now it is a million times worse. Have cracks on the corner of my mouth too Its SO painful. I've been[Show More]Hello! I'm wondering if there is any place where pictures are shared? I don't have a lot of symptoms that most of you have, however the inside of my lips, and now the front of my lips, are covered in what I would describe as blisters. It started about a month ago on the inside, cleared up, and now it is a million times worse. Have cracks on the corner of my mouth too Its SO painful. I've been researching like crazy and can't seem to find many pictures of allergic reactions or blisters and sores on the lips from this?!

• TeresaOctober 29, 2021 at 11:11 pm

  I am 69 year old female nurse and started Invisalign. First tray soreness in mouth which expected. Second tray my parotid glands hurt, had sore throat and headaches. On day 3 of the second tray at 10:30 in the evening started breaking out in huge hives all over, throat was tight, lightheaded and pulse rate fast. Started to feel like I was going to faint. Called 911 and popped the aligners out. I w[Show More]I am 69 year old female nurse and started Invisalign. First tray soreness in mouth which expected. Second tray my parotid glands hurt, had sore throat and headaches. On day 3 of the second tray at 10:30 in the evening started breaking out in huge hives all over, throat was tight, lightheaded and pulse rate fast. Started to feel like I was going to faint. Called 911 and popped the aligners out. I was very shaky when paramedics arrived and BP elevated. This was a near if not anaphylactic reaction. I didn’t feel right for a week. Having a hard time getting anyone to help me find out what is in these to cause such a bad reaction. Also out $2000.00. NOT a good experience

• DelOctober 7, 2021 at 10:07 pm

  Yesterday I started noticing symptoms and was wondering if it was because I lagged on cleaning them with the crystals. Guess I’ll have to call the doctor.

• ClaudetteOctober 7, 2021 at 8:22 pm

  I wore my Invisalign braces for about 1 1/2 years before I became allergic to them. This past summer I started to have pain in my mouth, throat, and tongue, lose of taste, and swollen parotid gland on right side. I stopped wearing the braces 9/9/2021 (4 weeks ago). I have been on two courses of prednisone. The symptoms have gotten slightly better but are still present. My allergist says it could t[Show More]I wore my Invisalign braces for about 1 1/2 years before I became allergic to them. This past summer I started to have pain in my mouth, throat, and tongue, lose of taste, and swollen parotid gland on right side. I stopped wearing the braces 9/9/2021 (4 weeks ago). I have been on two courses of prednisone. The symptoms have gotten slightly better but are still present. My allergist says it could take 6-8 weeks before the problems clear up. How long did it take for other folks to have their problems clear up? Oh, I also had a EGD and it was found that I have a non-bleeding ulcer in my small intestine. Could this be related to the braces as well?

• CarlAugust 26, 2021 at 6:09 pm

  I am hating the fact that I have to type these comments. I am in the middle of the treatment with about 6 months to go and yesterday I had the worse break out yet. I've already been having fatigue issues, dry mouth, some eye focus problems but never would have guess it was with my braces. I put a new tray in before bed the night before last and I woke up to my neck swollen, the entire half side of[Show More]I am hating the fact that I have to type these comments. I am in the middle of the treatment with about 6 months to go and yesterday I had the worse break out yet. I've already been having fatigue issues, dry mouth, some eye focus problems but never would have guess it was with my braces. I put a new tray in before bed the night before last and I woke up to my neck swollen, the entire half side of my body that I slept on swollen including my face - baggy eyes. Restricted breathing, brain fog and a slight cough. It was the worse reaction I've had in a while. I've noticed it doesnt happen so bad with every tray but this one I actually rinsed and brushed clean and it stll gave me a reaction. I am hesistant to put these things back in my mouth. Going through Covid and now this - i dont care about the money I just want my health back. I wanted a good smile but since ive had these in my mouth I definitely suffered from a lot of fatigue.

• KarenAugust 1, 2021 at 11:00 pm

  Blistering lips inside of mouth, cracks and drooling (non stop) on corners of the mouth. Dry mouth and burning. I have tried for 3 months for the dentist to remove the buttons to no avail. In constant pain

• ShellyJuly 27, 2021 at 1:47 pm

  I have been in treatment since March 2021. For the past couple of months, my tongue feels funny, like it has a film over it. At my recent dentist appointment for cleaning and to receive my next set of aligners, I asked my dentist to check up a red bubble enlargement on the top of the right side of my tongue. They recommended seeing an oral surgeon. Of course now I am freaking out! A month pri[Show More]I have been in treatment since March 2021. For the past couple of months, my tongue feels funny, like it has a film over it. At my recent dentist appointment for cleaning and to receive my next set of aligners, I asked my dentist to check up a red bubble enlargement on the top of the right side of my tongue. They recommended seeing an oral surgeon. Of course now I am freaking out! A month prior, I had a mouth full of canker sores that have since disappeared, however this little bump on my tongue has me freaked out along with waking up with a very dry mouth. Has anyone else experienced anything like this with Invisalign?

• MelissaJuly 16, 2021 at 9:43 pm

  I had issues with severe dry mouth from the beginning. I was hoping that when I got used to the Invisalign it would get better. But it got progressively worse and I developed additional symptoms …dry mouth, sore tongue and roof of mouth (feels like a burn), red gums and inside of mouth, nausea, headache, fatigue, feeling feverish. Just an all over unwell feeling. I mentioned it at my Ortho. appoi[Show More]I had issues with severe dry mouth from the beginning. I was hoping that when I got used to the Invisalign it would get better. But it got progressively worse and I developed additional symptoms …dry mouth, sore tongue and roof of mouth (feels like a burn), red gums and inside of mouth, nausea, headache, fatigue, feeling feverish. Just an all over unwell feeling. I mentioned it at my Ortho. appointments and was basically brushed off. I was able to make it through treatment but when I got the retainers it was intolerable. I’m very disappointed that I wasted a lot of money. I can’t wear a retainer so my teeth will go back to where they were to start with.

• StuartJune 30, 2021 at 1:04 am

  Male 55 years, fit, healthy, no prev doctor treatments. I snowboard, mountain bike and run amongst other activities. First day of invisalign I noticed that having my first meal (about 5hrs after initial fitting) that my taste sensation was reduced. First night sleep a bit restless and sweating up which I would have expected maybe from some mouth soreness getting used to the invisalign. I woke at 3[Show More]Male 55 years, fit, healthy, no prev doctor treatments. I snowboard, mountain bike and run amongst other activities. First day of invisalign I noticed that having my first meal (about 5hrs after initial fitting) that my taste sensation was reduced. First night sleep a bit restless and sweating up which I would have expected maybe from some mouth soreness getting used to the invisalign. I woke at 3.00am with my glands so swollen that my skin was stretched tight around my whole neck and breathing was somewhat restricted. I removed the invisalign immediately and noticed a reduction in swelling within the hour and almost gone in 6hrs. I then looked on line and have found several sites that report issues. I was going to try them again in the daytime tomorrow though after reading these comments no longer feel that would be the right choice. Chemicals in the mouth for 22hrs a day does not seem to be real smart practice. Just posted this to keep everybody aware of issues.

• davidJune 19, 2021 at 11:05 pm

  I had to stop using Invisalign after 27 days due to multiple health issues: After 15 days, I started having chest pain: By Day 17, it was esophageal and I had discomfort swallowing. By day 24; I was dizzy, light headed, couldn't focus, reading and small objects of focus became a bit blurry. By day 26, I thought I was having a heart attach: I went in for an EKG (all good). They had me drink a [Show More]I had to stop using Invisalign after 27 days due to multiple health issues: After 15 days, I started having chest pain: By Day 17, it was esophageal and I had discomfort swallowing. By day 24; I was dizzy, light headed, couldn't focus, reading and small objects of focus became a bit blurry. By day 26, I thought I was having a heart attach: I went in for an EKG (all good). They had me drink a numbing agent for my esophagus (to see if that was where the pain was coming from and it was). I was diagnosed with GERD and given Omeprazole / Prilosec (which I did NOT take!). I was told it was stress related and that I needed to be calm. I am not stressed and I have always been healthy so this just didn't make sense to me. I did a little searching online and found this website and see several comments describing my symptoms. I then found the name of the plastic Invisalign uses (methylene diphenyl diisocyanate & 1.6-hexanediol); in which chemicals like formaldehyde and lithium aluminum hydride are used in its production. With that all said, I took the trays out 36 hours ago and am feeling better. Went to my Homeopathic Chiropractor yesterday for a detox agent. I am hopeful I will have 100% recovery soon. Invisalign really needs to share the potential effects of the use of their product, with their customers. I could have stopped its use 2 weeks ago if I had been informed. It would have saved time worry, time, medical bills, travel expenses and of coarse, my health.

• LoriMay 27, 2021 at 1:43 pm

  I've been using Invisalign for about 2 months. Right away I noticed excessive dry mouth, sore tongue, I'm getting cuts from the plastic and I've lost my sense of taste and smell. I woke up in the middle of the night choking and unable to breathe and was rushed to hospital with a severe asthma attack. I had no idea what caused it until I found this site. I have blurred vision which I couldn't und[Show More]I've been using Invisalign for about 2 months. Right away I noticed excessive dry mouth, sore tongue, I'm getting cuts from the plastic and I've lost my sense of taste and smell. I woke up in the middle of the night choking and unable to breathe and was rushed to hospital with a severe asthma attack. I had no idea what caused it until I found this site. I have blurred vision which I couldn't understand either. It breaks my heart to read these comments. We were all so hopeful to start these treatments only to be lied to and poisoned in the process. I'm grateful to you all for speaking out. Otherwise I may never have put the breathing difficulties and other symptoms down to the Invisalign. I did tell my dentist about the cuts and swelling and lack of taste and smell but she ignored it. Why does the FDA not have more power then this? Invisalign should have to pay for this!

• JohnMay 22, 2021 at 5:18 am

  I started getting sick three days after I started invisalign. Sore throat, fatigue, nausea, diarrhea, cold and hot sweats, Tests for COVID and strep came back negative. Took out my trays.

• J.April 25, 2021 at 4:37 am

  Been suffering with this for 2 years but so so painful to take off at this point also even broke/ shattered a root canal that dentist replaced at his cost. I have tried several times to end treatment only to be ignored or be treated very uncomfortably. I have severe neck and back pain sleep very little. My face all left side nose, eye and ear hurt almost constantly. Vision in left eye has changed.[Show More]Been suffering with this for 2 years but so so painful to take off at this point also even broke/ shattered a root canal that dentist replaced at his cost. I have tried several times to end treatment only to be ignored or be treated very uncomfortably. I have severe neck and back pain sleep very little. My face all left side nose, eye and ear hurt almost constantly. Vision in left eye has changed. My taste and smell is hardly there anymore what is taste terrible I can no longer tolerate the taste of meat. I have lost 70 lbs. I pray for the day this thing comes off! I have also broke many of my teeth from the constant grinding in which I have paid for those fillings! Maybe this does work for some but this has been this worse nightmare for me! This is the short story of it much of it being untold. Maybe look it rapid braces or another alternative? I would not suggest this after my experience, but goodness I would hope this don’t happen to many! I still do not feel it right for them to make us tough it out! As a single mother this has been a very scary experience one I’m still questioning:(

• AshFebruary 21, 2021 at 12:26 am

  Wow... I am on 9 of “17” and all I can say is that there is something “off” about all of this. I began having issues after the 3rd or 4th. My issues are swollen eyelid especially on my weaker eye, dry itchy skin around my nostrils, foul smell from my nostrils, Roof of my Mouth is ITCHY all night... sore stomach, sharp shooting pains in my head, cough, feels like something is “stuck” in my airway, [Show More]Wow... I am on 9 of “17” and all I can say is that there is something “off” about all of this. I began having issues after the 3rd or 4th. My issues are swollen eyelid especially on my weaker eye, dry itchy skin around my nostrils, foul smell from my nostrils, Roof of my Mouth is ITCHY all night... sore stomach, sharp shooting pains in my head, cough, feels like something is “stuck” in my airway, coughing attacks after waking up feeling like I had breathed in carbon monoxide or something all night long.... As someone who has never had any health problems, work out regularly, healthy diet, non smoker, non drinker... this is clearly something to do with the treatment. I look pale, my eyes look beyond tired. The #1 sign something is wrong is my lack of motivation and willpower. I’ve become so lazy I don’t workout, I have no appetite, when I don’t wear them for 3-6 hours I start feeling normal again... I feel a “micro sweat” like a permanent panic or anxiety... especially on the forehead, almost feverish, and my hair line has tingling sensations all day long. My pre-existing joint injury that lead to poor circulation in my right foot has WORSENED. Definitely reaps havoc on our immune systems for some reason... should be thoroughly investigated before it gets more people irreversibly sick.

• VanessaFebruary 17, 2021 at 4:16 am

  Hi everyone, I apologize in advance for if my grammar is not great because I’m French. I started invisalign less than a month ago and after only few days I experimented some sort of migraines and a cough. My stomach was bloated. I started to feel extremely tired and a bit down and though it might be the flu. After 2 weeks I had a severe episode of vomiting with tangling feeling in my hands, feet a[Show More]Hi everyone, I apologize in advance for if my grammar is not great because I’m French. I started invisalign less than a month ago and after only few days I experimented some sort of migraines and a cough. My stomach was bloated. I started to feel extremely tired and a bit down and though it might be the flu. After 2 weeks I had a severe episode of vomiting with tangling feeling in my hands, feet and legs. My mouth and tongue were numbed. I had at the same time an awful migraine... thought it was a nasty virus. Was pretty happy about the nausea... in a week I have lost 6.7 pounds but can barely hold a soup. I went to the doctor when I was coughing continuously some infected mucus and barely could walk without feeling dizzy (I haven’t seen a doctor in a decade. I don’t smoke. Don’t drink. I practice running and I eat a very healthy diet).... the doctor thought it was a flu who degenerated into a bad infection. He gave me under a strong antibiotic. I started to feel better but the feelings of nausea was still strong. The cough and the shortness of breath still present but the fever went away. Two nights ago I felt like dying in my bed. Another round of dry asthmatic cough and instinctively I removed my Invisalign’s... only to notice that... my cough stopped immediately. I waited a bit and everything seemed to calm down. I did wake up every night after 4 hours of sleep. The next day my nausea was gone and I could restart to eat again. This things is a straight poison... I’m glad I found your website, it seems that a lot of info about Invisalign are hard to find.

• MarciaJanuary 30, 2021 at 2:26 am

  First 3 week were fine. Then I woke up on a Sunday with what felt like was a hair in back of my throat. It progressed from there. I finally had it and took a flashlight to my mouth and was shocked when I saw huge white bumps on the back of my tongue--thats what was causing the discomfort. I contact my doc and gave me some anti fungal mouth rinse but it isn't helping. I took out the aligner for[Show More]First 3 week were fine. Then I woke up on a Sunday with what felt like was a hair in back of my throat. It progressed from there. I finally had it and took a flashlight to my mouth and was shocked when I saw huge white bumps on the back of my tongue--thats what was causing the discomfort. I contact my doc and gave me some anti fungal mouth rinse but it isn't helping. I took out the aligner for 2 days and it did get better. Hoping that I was crazy or maybe had a touch of a cold or something, today I put my #4 in and a couple hours later the feeling in the back of my throat is BACK! SO MUCH MONEY WASTED! Never in a million did I think I'd have this experience, but when you really stop and think-- You shouldn't have this foreign plastic in your mouth for hours and hours.

• DonnaDecember 10, 2020 at 5:30 am

  I too was excited to use the Invisalign to have a pretty smile. After having them in for ONLY five days I suddenly experienced pain radiating up my right jawline and felt HUGE swollen gland just suddenly swell up. The entire right side of my jaw was so swollen you could not distinguish my jawline. Called dentist..he said go to emergency dept. Was given antibiotics. Next morning after having bee[Show More]I too was excited to use the Invisalign to have a pretty smile. After having them in for ONLY five days I suddenly experienced pain radiating up my right jawline and felt HUGE swollen gland just suddenly swell up. The entire right side of my jaw was so swollen you could not distinguish my jawline. Called dentist..he said go to emergency dept. Was given antibiotics. Next morning after having been on antibiotics same thing occurred this time the left side of my jaw blew up so swollen and tender it was scary. Dentist saw me that day and said I was so swollen it looked like mumps ! But dentist said knew it was not mumps. . Was put on even stronger and higher dose of antibiotics. Saw a different dentist who said it was his opinion that it was from an allergic reaction to the plastic aligners. All my lymph nodes in neck are swollen. Stopping treatment. Wish I had researched and found this site sooner.

• DeboraNovember 11, 2020 at 7:11 pm

  I am 57 years old and decided I wanted a pretty smile. I was told I would need to do Invisalign for 11 months. I was 6 months in when I started having severe headaches, ringing in my ears, swelling in lower lip, nervousness (hands shaking), and jaw pain. My lower front tooth became loose and I feared that I may lose the tooth. I then noticed gum recession at the 2 lower front teeth, which I di[Show More]I am 57 years old and decided I wanted a pretty smile. I was told I would need to do Invisalign for 11 months. I was 6 months in when I started having severe headaches, ringing in my ears, swelling in lower lip, nervousness (hands shaking), and jaw pain. My lower front tooth became loose and I feared that I may lose the tooth. I then noticed gum recession at the 2 lower front teeth, which I did not have prior to Invisalign. My dentist told me that it was going to happen anyways, at some point. Needless to say, it got so bad that I had the buttons removed from my teeth and discontinued the Invisalign. I then had to go to a surgeon to repair the receded gums - $2000.00 out of pocket cost. Invisalign - $5000.00. I like many others came to the conclusion that my health was much more important than the pretty smile. My advice to others: DO YOUR HOMEWORK AND RESEARCH.....READ REVIEWS (Good & THE BAD). I have to wonder if moving the teeth in such a short amount of time, along with the plastic in your mouth every day for 22 hours a day is just plain wrong! Traditional braces move the teeth over a span of 2-5 years?

• MarinaNovember 6, 2020 at 2:01 am

  I actually tried smile direct aligners and after wearing them for Less than a month I noticed swollen glands, a dry cough, and sore throat. Apparently smile direct uses the same materials. I just spent $2000 and I cant use them anymore. I am very upset about this. I'll call tomorrow to see how I can be accompdated. Thanks everybody for sharing your experiences

• LarissaOctober 15, 2020 at 7:15 pm

  Has anyone suffered from nausea, dizziness, sometimes. My daughter has been on Invisalign for 2 years and after the first month I had to take to hospital. No one can help, so recently I suspected allergy to the plastic. She has lost considerable 116lbs to now 97lbs she is 5'5" over 2 years. She is a person who loves her steak and potatoes. We thought greasy foods were the culprit but now it's bas[Show More]Has anyone suffered from nausea, dizziness, sometimes. My daughter has been on Invisalign for 2 years and after the first month I had to take to hospital. No one can help, so recently I suspected allergy to the plastic. She has lost considerable 116lbs to now 97lbs she is 5'5" over 2 years. She is a person who loves her steak and potatoes. We thought greasy foods were the culprit but now it's basically any food or no food she is naseated. She takes off Invisalign so she can be comfortable.

• GinApril 27, 2020 at 10:55 pm

  If you are thinking of the clear aligner trays, please reconsider! I wore them for 6 weeks and it's been a week now and I am still feeling some effects from it. It started with slightly swollen, sore red lips, dry mouth and throat, as well as a tingly feeling on my tongue. I just figured it was me getting used to it. I continued to wear them with the minor issues, but the throat discomfort started[Show More]If you are thinking of the clear aligner trays, please reconsider! I wore them for 6 weeks and it's been a week now and I am still feeling some effects from it. It started with slightly swollen, sore red lips, dry mouth and throat, as well as a tingly feeling on my tongue. I just figured it was me getting used to it. I continued to wear them with the minor issues, but the throat discomfort started to get worse and I was coughing some too. My throat got a lil sore towards the end of the sixth week with some swelling. I went to bed that night and woke up to swollen lymph nodes under my chin and in my neck. I also felt like my throat swelling was worse and had some trouble swallowing. I removed them that morning and the swelling went down fairly well over the next few days, but still flares up sometimes. I also developed shortness of breath, wheezing and feeling like I have a band around my chest with some coughing. It is an awful feeling. It can be hard to do physical activity and still is sometimes. I'm a pretty active person too. It also causes anxiety, sleep problems, blood pressure and heart rate changes. I'm hoping that this all eventually goes away. These things should be illegal. There is no safe thin plastic to leave in your mouth like this! Please do traditional braces or keep the smile that you have. Your quality of life is way more important!

• BarbaraApril 9, 2020 at 2:37 am

  I started using aligners From smile direct approximately one month ago and I started to develop severe dry mouth and sores on the inside of both cheeks This was probably due to the aligners being too Sharp and were cutting into my cheek resulting in open sores The pain and discomfort in my mouth made eating unbearable. My lips became swollen and having a simple conversation was almost impossibl[Show More]I started using aligners From smile direct approximately one month ago and I started to develop severe dry mouth and sores on the inside of both cheeks This was probably due to the aligners being too Sharp and were cutting into my cheek resulting in open sores The pain and discomfort in my mouth made eating unbearable. My lips became swollen and having a simple conversation was almost impossible without slurring. I stopped using the aligners but the symptoms became more dominant and more unbearable. Due to the coronavirus seeing a dentist was almost impossible Until it became serious. I was examined and told I had an allergic reaction to the aligners and open sores from a poor fit. I developed an infection in my mouth as well I was given an oral mouthwash with an antihistamine and lidocaine for the pain. I’m praying this helps but as of now I do not see much improvement. I will not use them anymore and I am requesting a full refund

• StaceyApril 3, 2020 at 1:32 pm

  During my Invisalyn treatment I had tiny ulcers on my tongue. I finished the treatment and am now using the retainers. However, I still get the ulcers and now have a somewhat salty taste in my mouth. Are others experiencing the same? Any ideas or suggestions?

• KatieMarch 23, 2020 at 7:14 pm

  Samantha I am so glad I saw your post! I have felt like I have been going nuts but your experience is so close to mine....the first few weeks were fine...pain but as one would expect from braces. Then I started feeling rundown and just off and then for the first time in my life I had a panic attack...my anxiety is near constant but the thing that really started to freak me out was the swallowing.[Show More]Samantha I am so glad I saw your post! I have felt like I have been going nuts but your experience is so close to mine....the first few weeks were fine...pain but as one would expect from braces. Then I started feeling rundown and just off and then for the first time in my life I had a panic attack...my anxiety is near constant but the thing that really started to freak me out was the swallowing...it got to the point where after just a couple bites of even eggs I couldn't swallow anything except water and even that got hard....nothing is swollen and all structural tests and blood work is normal, normal chest expat, normal ekg...this is the only new thing I have introduced. Also have headaches, neck pain, racing heart, chest pain and heaving breathing etc. I stopped wearing them 2 days ago and by today I was able to eat a fairly normal meal. I am going to leave them off for a few more days and if I continue to feel better, no more of this for me!

• KelleyMarch 9, 2020 at 6:17 pm

  CANCER? I am 47 years old, I have been wearing invisalign for two years, just had my first endoscopy and the results came back with gastric intestinal metaplasia (pre-cancerous lesions that puts people at a low risk for stomach cancer). I am questioning if the chemicals in invisalign swallowed in saliva cause this?

• AnnaFebruary 21, 2020 at 9:35 pm

  Hi, during first round of invisilign I developed extreme fatigue, gut problems, irritable bowl syndrome, my nose was blocked like from allergy I had to take Zirtek all the time, had to be a strict fodmap diet. Than I took them off, my health got better. Than after wearing just overnight retainers my teeth shifted back and I had to order new Invisalign and now I wear them again and all my gut probl[Show More]Hi, during first round of invisilign I developed extreme fatigue, gut problems, irritable bowl syndrome, my nose was blocked like from allergy I had to take Zirtek all the time, had to be a strict fodmap diet. Than I took them off, my health got better. Than after wearing just overnight retainers my teeth shifted back and I had to order new Invisalign and now I wear them again and all my gut problems and blocked nose are back(((

• SandraFebruary 9, 2020 at 7:37 pm

  So glad to find this page! I starting getting dry mouth initially, that turned into excessive water consumption, sore throat, feeling that something is stuck in my throat that just kept getting worse. I went to the Urgent Care thinking that I had strep (Negative). then because I had gastro issues my family doc that sent me to get an EGD - nothing there. On to ENT after a barium swallow and vide[Show More]So glad to find this page! I starting getting dry mouth initially, that turned into excessive water consumption, sore throat, feeling that something is stuck in my throat that just kept getting worse. I went to the Urgent Care thinking that I had strep (Negative). then because I had gastro issues my family doc that sent me to get an EGD - nothing there. On to ENT after a barium swallow and video swallow, still nothing! My mother has thyroid issues so I was next sent to and Endocrinologist but that all checked out OK. He suggested it might be sjogren's. When I started to look into that I see all the dental link and then is hit me... It's the Invisalign ! So what do I do? Stop treatment in the middle, i guess. Can't imagine I get any of the costs back, but I sure have dished out a lot in co-pays and deductibles that were not covered my by insurance. I did read the fine print and only saw a reference to some may get a sore throat but Sjogrens?

• SamanthaFebruary 5, 2020 at 5:00 pm

  OMG. I wish I would have seen these comments sooner. The chapped bleeding lips are the least of my symptoms. I have had a horrible cough for months, feeling of fluid in my chest. Since I started my treatment I have had horrible trouble chewing my food or swallowing any kind of medicine. Yesterday i couldnt even swallow scrambled eggs. I feel like Im choking. Tisay its hard to even swallow saliva. [Show More]OMG. I wish I would have seen these comments sooner. The chapped bleeding lips are the least of my symptoms. I have had a horrible cough for months, feeling of fluid in my chest. Since I started my treatment I have had horrible trouble chewing my food or swallowing any kind of medicine. Yesterday i couldnt even swallow scrambled eggs. I feel like Im choking. Tisay its hard to even swallow saliva. My throat and tongue are horribly swollen, to the point that its hard to breath. I am having anxiety and panic attacks. My tongue is burning/tingling. Some nights I wake up gasping for air. Now the latest is chest pain! Im 35, I workout everyday and eat healthy. Ive never been sick really. My EKG came back abnormally and now I have to see a Cardiologist at 35. I literally cant even work this week because i feel like im dying. I asked my Orthodontist about this months ago and he claims hes never heard of such a thing.

• KevinJanuary 30, 2020 at 1:14 pm

  I’ve recently started my Invisalign treatment December 3 2019 and now almost 2 months in I’ve been experiencing anxiety disorder, heart palpitations, and tingling in my left arm. I’m 36 and never seen a doctor in my life for any health concerns I’m very health conscious with the food I eat and exercise regularly I’m a none smoker and none drinker. So when these issues arise I knew automatically wh[Show More]I’ve recently started my Invisalign treatment December 3 2019 and now almost 2 months in I’ve been experiencing anxiety disorder, heart palpitations, and tingling in my left arm. I’m 36 and never seen a doctor in my life for any health concerns I’m very health conscious with the food I eat and exercise regularly I’m a none smoker and none drinker. So when these issues arise I knew automatically what it was, I’m going in to see my orthodontist to explain these issues today to see what is his response.

• LauraJanuary 28, 2020 at 1:18 pm

  Oh my God! I am so glad I found this. After about a month using Invisalign I started to get constant sore throats. Then dry uncontrollable coughs. Initially I went to see my doctor and he said probably just a cold. But it continued and I got HUGE swollen lymph node in my neck which he insisted I get biopsied. It came back negative but I continued to be ill. I am beyond miserable and cannot s[Show More]Oh my God! I am so glad I found this. After about a month using Invisalign I started to get constant sore throats. Then dry uncontrollable coughs. Initially I went to see my doctor and he said probably just a cold. But it continued and I got HUGE swollen lymph node in my neck which he insisted I get biopsied. It came back negative but I continued to be ill. I am beyond miserable and cannot sleep well at night due to coughing and throat so sore I feel like there is a knife stuck. I asked the doctor if it could be the Inivisalign and he said no. However I did a test and wore nothing for 3 days. My sore throat almost vanished and cough improved. I have 3 months left. I hate to have wasted all this money but I don't think I can go on.

• MellissaJanuary 23, 2020 at 11:39 am

  I’m currently on aligner 14 of my invisilign treatment and although I am not experiencing some of the mentioned above allergic reactions; i have severe TMJ problems that have never been present before aligners. I’m clenching, my massater muscles are in spasm, unbearable neck pain that has moved into my shoulder and arm now. I have had to have 60 units of Botox to just relax my jaw muscles. My de[Show More]I’m currently on aligner 14 of my invisilign treatment and although I am not experiencing some of the mentioned above allergic reactions; i have severe TMJ problems that have never been present before aligners. I’m clenching, my massater muscles are in spasm, unbearable neck pain that has moved into my shoulder and arm now. I have had to have 60 units of Botox to just relax my jaw muscles. My dentist refuses to believe that it is the Invisilign causing the spasms. Is anyone experiencing this type of reaction?

• AimeeDecember 12, 2019 at 9:14 am

  I also haven’t experienced allergies like others, I have experienced nausea, heart palpitations, anxiety attacks, loss of sleep/broken sleep. This started at about a month into my treatment. Have been back and forth to emergency, doctors, cardiologists. Had multiple blood tests and stool samples. Everything comes back clear!! Have been feeling crazy!! Have now just realized that it’s invisalign!! [Show More]I also haven’t experienced allergies like others, I have experienced nausea, heart palpitations, anxiety attacks, loss of sleep/broken sleep. This started at about a month into my treatment. Have been back and forth to emergency, doctors, cardiologists. Had multiple blood tests and stool samples. Everything comes back clear!! Have been feeling crazy!! Have now just realized that it’s invisalign!! Started googling and found all these comments! Makes me feel not so alone. I will no longer be going on with my invisalign treatment!

• RoseNovember 15, 2019 at 7:07 pm

  I am currently on tray 8 of Invisalign, and my teeth are looking very nice. But, unlike most others on this site, I am not having tongue, lip, mouth issues. What I am having, however, is gastric issues, lethargy, and headaches. I have had multiple doctor appointments, X-rays, supplements, Gas X, upcoming gastroenterologist appointment, etc. I have had heartburn perhaps 3 or 4 times in my entire l[Show More]I am currently on tray 8 of Invisalign, and my teeth are looking very nice. But, unlike most others on this site, I am not having tongue, lip, mouth issues. What I am having, however, is gastric issues, lethargy, and headaches. I have had multiple doctor appointments, X-rays, supplements, Gas X, upcoming gastroenterologist appointment, etc. I have had heartburn perhaps 3 or 4 times in my entire life, so gastric issues are foreign to me. I look as if I am 4 months pregnant (I’m 65), and am so uncomfortable by the end of the day, I have to wear sweats. The timing is such that I can possibly associate it with the use of the trays, and will stop wearing them beginning today. I am making an appointment with my orthodontist in going forward. I have little faith that he will agree with my assumption of issues with the Invisaligns but feel confident, after reading others experiences, I have gotten to the crux of my gastric problems.

• MarshaOctober 29, 2019 at 11:07 am

  I’ve been using Invisalign for 8 months. I was so excited to finally have a an overbite and just make my smile look nicer. I’m probably older than most who get these liners but I couldn’t afford braces when I was younger. I went to a highly recommended orthodontist and he showed me on his high end machine what my teeth look like and what it will look like after I get theses liners. I was ready[Show More]I’ve been using Invisalign for 8 months. I was so excited to finally have a an overbite and just make my smile look nicer. I’m probably older than most who get these liners but I couldn’t afford braces when I was younger. I went to a highly recommended orthodontist and he showed me on his high end machine what my teeth look like and what it will look like after I get theses liners. I was ready to start. The first week of using the liner I felt nauseous and very tired but I attributed that to the saliva buildup I was experiencing and nothing more. As the months progressed I developed a horrible coughing which gave me terrible headaches and I felt weak and tired. I was coughing so hard I broke a blood vessel in my eye. I thought I was just sick. I went to visit my daughter in NJ for ten days. While there I was having terrible symptoms like pneumonia or flu so I went to an urgent care center and I was given flu medication even though the swab didn’t show that I had the flu. I didn’t get better and somehow managed to fly home so I could go to my GP who said I probably have pneumonia and he gave me cough medication which I’m still taking and will stop in a few days. I also took Mucinex and Tylenol. My husband has been very worried about my health so he did some investigating online and found others with my symptoms. All of which were wearing Invisalign. I sent an email to my orthodontist and he replied back to me saying that in all his 19 years of practice only 3-4 people have had a reaction and it usually occurs at the very beginning of using the liners and he’d notice if I was allergic. He suggested I stop wearing the liners for 2-3 days to see if I felt better and to call him. Well I did take the liners out yesterday and I woke up this morning without the horrific coughing. I slept well last night. I can’t tell you how much better I fell this morning. My GP set up an appointment a few weeks ago for me to see a pulmonologist about my coughing which I’m going to this morning. I’d like to know what materials are used to make the Invisalign liners. That’s going to be my next question to my orthodontist. I hope that the plastic isn’t harmful to my health long term.

• TerriOctober 13, 2019 at 12:18 am

  By my email you will realize that I work in a health related field. I wore invisalign for two years and was very compliant. I asked before wearing them if there was any estrogenic material in the plastic. I was an 11 year survivor of Breast Cancer and I am careful about the amount of estrogenics in plastic. I was assured that there was not any. I had small issues but I was referred to Mayo f[Show More]By my email you will realize that I work in a health related field. I wore invisalign for two years and was very compliant. I asked before wearing them if there was any estrogenic material in the plastic. I was an 11 year survivor of Breast Cancer and I am careful about the amount of estrogenics in plastic. I was assured that there was not any. I had small issues but I was referred to Mayo for an MRI for unrelated issues and they saw a large shadow. After being an 11 year survivor to a low stage cancer, my lymph nodes in my neck are 91-100 percent (hghest range) estrogen. I am now battling metastatic Breast Cancer. Because of where my tumors are in my neck, near my thyroid, I asked pulmonologist is these inflamed nodes were in a pathway for something I would have had in my mouth. His answer was it is a perfect pathway and that was when they just thought I had swollen nodes. If I had not been a survivor they would not have done a biopsy of the nodes and found that they are estrogen based cancer. This is simply to raise awareness, and not to raise fear. Invisalign is made of MDI polyeurothane plastic and in 2007 the World Health Association said use of this plastic should never be discussed for oral use. Also, one study we found showed that MDI polyeurothane caused bronchial tumors and collapsed lungs in rats. I am writing this from Mayo where I am for more testing. I was diagnosed last year at this time. For me, it is not worth the risk.

• TarachaOctober 1, 2019 at 5:11 am

  I started my Invisalign in March of 2019. I was to start on tray twelve this past Tuesday. Four months ago I started having issues where I felt dizzy sporadically. I do not wear daily glasses but my vision started to get gradually off. I can see but I have to focus manually. It is as if my brain doesn't automatically tell my eyes to focus. Within the last month I have started to lose my sense of [Show More]I started my Invisalign in March of 2019. I was to start on tray twelve this past Tuesday. Four months ago I started having issues where I felt dizzy sporadically. I do not wear daily glasses but my vision started to get gradually off. I can see but I have to focus manually. It is as if my brain doesn't automatically tell my eyes to focus. Within the last month I have started to lose my sense of smell on some things. Then I started to have a foul smell in my nose that just comes randomly. It is as if it is inside. I even go as far as take a shower to clear my airways, and wash my hair when I smell it. It is still there. It smells like spoiled turkey or slight rot. I had sores in my mouth in the previous month, then sore tongue followed. I had a sore throat and constant runny nose. My orthodontist told me none of my symptoms were related to the invisalign. He advised they are safe. He never mentioned any hypo allergenic version. When I told him my sense of smell seems directly connected sense they are in my mouth. He damn near laughed it off as if it couldn't possibly be true. In addition to all this, I have not been keeping track of things well. I am usually great with keeping track of things and order. But the last month I notice I have something like a brain fog. I don't smoke. I don't do any drunks. I barely drink twice a month. I workout and eat right. I have never felt this in 40 years. I feel completely off. I have been to my General practitioner, the Nurse practitioner, the gyno, and the Optometrist. They all have no idea why I am feeling like this. This entire ordeal is mimicking the Roundup cases that surface in the most recent news. For years the people were subject to what was told to be "safe" for them but look how that ended. I took those aligners out asap when I found this yesterday. I am taking all this back to my Orthos office and demanding some refund. I would rather have a small gap than a damaged neuro system. I mean WTH. Why wouldn't this be apart of the normal warning conversation... oh wait, I didn't get any warning information. And I DID ask about side affects. I will see what happens as I leave these off and let you all know. This is detrimental and needs to be addressed.

• BeckySeptember 8, 2019 at 11:32 pm

  I had been wearing invisalign for a few months when I started experiencing dizziness, blurred vision, facial neuralgia type pain, burning in my mouth, hands and feet. I did not connect invisalign to these symptoms at first but noticed when I took the trays out for the few days the symptoms would subside. I have seen physicians to rule out other causes of these symptoms and all tests are negativ[Show More]I had been wearing invisalign for a few months when I started experiencing dizziness, blurred vision, facial neuralgia type pain, burning in my mouth, hands and feet. I did not connect invisalign to these symptoms at first but noticed when I took the trays out for the few days the symptoms would subside. I have seen physicians to rule out other causes of these symptoms and all tests are negative. I have had these out for approximately 2 months and most of the symptoms have subsided but I still have some residual symptoms such as burning sensations in my hands and feet. My dentist and I have contacted the company but they are not responding to my telephone call or email.

• RegretsAugust 23, 2019 at 1:15 am

  Don't do it, prioritise your physical health over beauty I am 18 trays into my treatment of invisalign. I had dizzy spells ever since i started wearing it but i ignored it cause it wasnt too bad. Until now. My dizzyness and headaches is so crippling its hard to get out of bed, and i cannot concentrate on my homework because of my dizzy spells. It feels like a rock is shoved into my brain, i always[Show More]Don't do it, prioritise your physical health over beauty I am 18 trays into my treatment of invisalign. I had dizzy spells ever since i started wearing it but i ignored it cause it wasnt too bad. Until now. My dizzyness and headaches is so crippling its hard to get out of bed, and i cannot concentrate on my homework because of my dizzy spells. It feels like a rock is shoved into my brain, i always feel groggy. I am speaking to my dentist about stopping treatment. I have seen the doctors but they have never heard of this before, and the dizzy medication they gave me does not help. Please reconsider if you are going to do invsialign. There are side effects they do not warn you about.

• SoniaAugust 13, 2019 at 5:34 am

  I developed post nasal drip, allergies and rapid heart beats due to Invisalign. I always sound like I have a soar throat. After I developing all these symptoms I looked online and realized others have too.

• KarenAugust 12, 2019 at 3:23 am

  I wore Invisalign several years ago. I wore all of the different trays that were given to me each time for the changes to be made. I finally had to stop because I felt like my left side of my mouth ( gum line) was always hurting. Told my dentist & he didn’t say much. Went to an oral surgeon , who looked at my mouth & gums & said I don’t see a thing wrong. On to a periodontist who again said I see[Show More]I wore Invisalign several years ago. I wore all of the different trays that were given to me each time for the changes to be made. I finally had to stop because I felt like my left side of my mouth ( gum line) was always hurting. Told my dentist & he didn’t say much. Went to an oral surgeon , who looked at my mouth & gums & said I don’t see a thing wrong. On to a periodontist who again said I see nothing wrong. So after many years now Ive been suffering with a constant burning on the left side. Had I known that Invisalign could have caused this I would have immediately stopped wearing the trays. Now what to do??

• RoseJuly 3, 2019 at 2:57 am

  I’ve had Invisaligns for 9 months. When I began I was completely healthy and competing in dance competitions. 3 months into the Invisaligns, I start getting tired, itchy skin, hair loss, sore throat, no more strength to do my dance competitions, muscle soreness, diarrhea. I went to several doctors and it took 6 months to find that it is the thyroid/autoimmune disease. I did some googling and found[Show More]I’ve had Invisaligns for 9 months. When I began I was completely healthy and competing in dance competitions. 3 months into the Invisaligns, I start getting tired, itchy skin, hair loss, sore throat, no more strength to do my dance competitions, muscle soreness, diarrhea. I went to several doctors and it took 6 months to find that it is the thyroid/autoimmune disease. I did some googling and found other people saying it is a side effect of the Invisaligns.

• JillJune 4, 2019 at 9:15 pm

  I was a healthy person prior to my use of invisalign. When I began use I came down with an upper respiratory illness, cough and sinus issues. My mouth was cut by the trays and I would have to saw the trays down and apply wax. My mouth was bleeding and sore. My dentist worked with me to continue. Before long I became sullen, pale and my hair became very thin and brittle. Even my skin became tough [Show More]I was a healthy person prior to my use of invisalign. When I began use I came down with an upper respiratory illness, cough and sinus issues. My mouth was cut by the trays and I would have to saw the trays down and apply wax. My mouth was bleeding and sore. My dentist worked with me to continue. Before long I became sullen, pale and my hair became very thin and brittle. Even my skin became tough and I had terrible nausea and abdominal pain. I proceeded to have an elevated lipase and was hospitalized for pancreatitis. I was a healthy, normal weight full time working woman prior to this. I live a no alcohol healthy lifestyle. I ended up having my gall bladder removed but continued to have pancreatitis. When I realized I was either allergic to or being poisoned by the plastic trays in my mouth I removed them immediately one night when my heart was beating so slowly I thought I would die. I had a small intestine biopsy which showed unexplained allergic reaction. When allergy tested at a later date I am not allergic to anything else. My health is compromised to this day and I continue to have abdominal pain and nausea but my color is improved and my hair has recovered and my skin. I wish my dentist had known to have me stop use when I became so gravely ill.

• SuzanneMay 25, 2019 at 1:10 pm

  I had invisalign for 9 months and had severe allergic reactions that my dentist said was impossible to react a month out. Almost died. Went to hospital 3 times, told doctors they basically laughed it off.Five years later now an autoimmune disease as my body couldn't deal with 9 months of hives, facial swelling, itch that was so bad.

• MarieApril 16, 2019 at 9:31 pm

  My daughter just spent 3 days back and forth to the ER for Epi shots, steroids, iv's and other antihistamines due to Invisalign. The dentist never spoke of any possible side effects/reactions to this product. If she was not able to get to the ER those 3 times in 3 days, I could be reporting a fatality. Do not take any meds. medical devices without finding out any potential reactions. I thank God s[Show More]My daughter just spent 3 days back and forth to the ER for Epi shots, steroids, iv's and other antihistamines due to Invisalign. The dentist never spoke of any possible side effects/reactions to this product. If she was not able to get to the ER those 3 times in 3 days, I could be reporting a fatality. Do not take any meds. medical devices without finding out any potential reactions. I thank God she is ok but her 4 young children and husband are also a wreck looking at what could have been a fatal outcome.

• kerryMarch 27, 2019 at 10:43 pm

  Started invisalign a few months ago. First 2 weeks seemed OK but within a few days of tray #2 I began to have ulcers in my mouth. I have had this issue in the past but nothing like this! I noticed the tray itself has sharp edges that cut the underside of my tongue. I stopped using the appliance thinking I would heal and then try again. The "buttons" that are placed on my teeth are also cutting i[Show More]Started invisalign a few months ago. First 2 weeks seemed OK but within a few days of tray #2 I began to have ulcers in my mouth. I have had this issue in the past but nothing like this! I noticed the tray itself has sharp edges that cut the underside of my tongue. I stopped using the appliance thinking I would heal and then try again. The "buttons" that are placed on my teeth are also cutting into my oral mucosa. I'm going on around 5-6 weeks of constant outbreaks of excruciating ulcers, swollen lips. I am horribly fatigued just from dealing with the pain. Every time I start to heal from one outbreak another starts. I have had up to 4 ulcers in every part of my mouth and tongue at the same time (unprecedented). I seem to also have a gum infection in one area that I manged wuite well before with daily flossing etc. I have had swollen lymph nodes which I assumed was my immune system trying to deal with the overwhelming tissue damage, but now I have laryngitis (never had it in my life and I am 61). I am normally a very healthy athletic woman with lots of stress management skills but this is really upsetting. I see the dentist tomorrow, and I am pretty much DONE. Especially after reading all of this. I guess crooked teeth are part of my destiny. Of corse I have already paid 5000$!

• SarahMarch 18, 2019 at 5:09 pm

  I started Invisalign and my TMJ pain got very severe with the 1st tray the pressure was awful- I was told I would have some pain so tried to push through - I looked up online and asked the Dentist- after trying muscle relaxers and pain meds my face neck and jaw pain got worse and the pressure in my sinuses was really painful then my nose started bleeding and cracked inside In several areas - I[Show More]I started Invisalign and my TMJ pain got very severe with the 1st tray the pressure was awful- I was told I would have some pain so tried to push through - I looked up online and asked the Dentist- after trying muscle relaxers and pain meds my face neck and jaw pain got worse and the pressure in my sinuses was really painful then my nose started bleeding and cracked inside In several areas - I have a large scabs come out everyday now I had to stop treatment after 1 week and now 5 days later no relief from the TMJ pain Still on muscle relaxers and pain medicine They are removing the attachments Friday I feel like they should’ve looked into this further before letting me purchase the invisaline as I answered the questionnaire as having TMJ Even though I was not having any symptoms prior to starting

• carolFebruary 5, 2019 at 4:50 pm

  After 3 weeks of using Invisalign my voice changed. It has got a lot worse (I sound like a deaf person speaks). I can't pronounce certain letters and I get out of breath when I speak. In addition I have had breathing and swallowing difficulties. I started the treatment in May 2018. I have since found out that there are life-threatening side effects to Invisalign! Had I known this I would not[Show More]After 3 weeks of using Invisalign my voice changed. It has got a lot worse (I sound like a deaf person speaks). I can't pronounce certain letters and I get out of breath when I speak. In addition I have had breathing and swallowing difficulties. I started the treatment in May 2018. I have since found out that there are life-threatening side effects to Invisalign! Had I known this I would not have taken the chance, and tried alternative orthodontic treatment (or none at all). As I haven't had swelling or anaphylaxis I have continued with the treatment but I am now considering stopping it.

• HeatherJanuary 19, 2019 at 2:23 pm

  anaphylaxis from Invisalign - I had anaphalaxis reaction to the polyurethane and carcinogenic toxic isocyanate that makes up the tray material! I couldn't breath! no one told me this could kill me! My throat swelled up, tight, heart racing, faint. It was horrible! I was scared! I was not warned this could happen! I went to the Invisalign website and it says they are non toxic..but that's a lie.[Show More]anaphylaxis from Invisalign - I had anaphalaxis reaction to the polyurethane and carcinogenic toxic isocyanate that makes up the tray material! I couldn't breath! no one told me this could kill me! My throat swelled up, tight, heart racing, faint. It was horrible! I was scared! I was not warned this could happen! I went to the Invisalign website and it says they are non toxic..but that's a lie. Im 39 and never had breathing problems in my life! why are these toxic ingretients not listed on the website? why wasn't I told? The trays are taken out, no refund given on the trays, just more medical bills from the hospital visit. its beyond me that they would use this stuff in the mouth. Saying something is FDA approved doesn't mean they went through product testing. I found reports on MAUDE (complaints reported to the FDA) showing MANY other people had been sent to the hospital because of difficulty breathing, sore throat, throat closing, dry mouth as well! For the billions Invisalign has made in profit they should offer organic materials. For example, use edible plastic made from seaweed. Its clear and can last 2 weeks before degrading. I know better than to put chemicals in my mouth. Especially cancer causing ones. This is probably why Invisalign makes it near impossible to find out what the trays are made of. Additionally, I read reports as far back as 2010 that the FDA warned Invisalign that the aligners were causing serious reactions in users. Ill never put that plastic back in my mouth ever again. Ill live with crooked teeth.

• DawnDecember 23, 2017 at 7:20 pm

  I just began the retainer treatment and it is obvious I have an allergic reaction to the plastic ones they offer. I now wasted a lot of time and money for me teeth to end up crooked again because back in the day they made all metal with gold retainers which my orthodontist says he cannot make.

• TeresaAugust 24, 2017 at 8:52 pm

  I didn't have a reaction for a couple of months but now my mouth feels like I rinsed with acid. Skin peeling off lips and even bled. Invisaligns screwed up my natural bite too. Thank God I have a great dentist. Lost a lot of sleep and caused me some major distress. Ortho didn't disclose upfront how grueling it would be or the risk. Didn't find out until I was to deep in to back out. Warnin[Show More]I didn't have a reaction for a couple of months but now my mouth feels like I rinsed with acid. Skin peeling off lips and even bled. Invisaligns screwed up my natural bite too. Thank God I have a great dentist. Lost a lot of sleep and caused me some major distress. Ortho didn't disclose upfront how grueling it would be or the risk. Didn't find out until I was to deep in to back out. Warning!!! False information about how easy and quick it is. Hope I haven't compromised my health.

• SandraJune 18, 2017 at 10:00 pm

  I got first trays March 2016. Didn't have much trouble, that I was aware was caused by the trays. I had been having headaches and neck spasms before the trays. After the trays the headaches became migraines, debilitating to say the least. At about tray 16 I noticed I was developing a rash around my mouth, in the corners and under the lower lip. Thought it was from the dry winter air. Tried everyth[Show More]I got first trays March 2016. Didn't have much trouble, that I was aware was caused by the trays. I had been having headaches and neck spasms before the trays. After the trays the headaches became migraines, debilitating to say the least. At about tray 16 I noticed I was developing a rash around my mouth, in the corners and under the lower lip. Thought it was from the dry winter air. Tried everything to clear it up. I could feel the rash start burning. Did not equate it with the trays. It would go away partially and then I would feel the burning and know immediately that I would have a bright red semi-circle around my mouth. My tongue also started hurting and was irritated. It hurt even drinking water. The headaches were still persistent, and I was starting to loose my appetite as food tasted bad and it was increasingly difficult to chew, I developed stomach problems, a cough and dry heaves as a result. To top off all that, my dentist was never present when the trays were handed to me in the office and my attachments were never checked. I was on set 24 of 35 when I started complaining about the fit of the trays. At set 29 the dentist's tech actually looked at my teeth and said that the alignment was off and took more impressions. When I went in to pick the next set up I was told that some of the attachments had been improperly placed and I needed some more attachments and would have to wear another 24 sets of trays. I, too, have sensitivities to the weirdest stuff and it got worse when I started this treatment. Never connected the two. Although I did have a bit of a reaction in the beginning just thought I was overreacting. But I did have bouts of facial hives, which I put down to stress and would take massive doses of Benadryl to counteract them. This seemed to work to alleviate the pain and anxiety that it caused to an extent, but I still did not equate the signs and symptoms with the trays. I did notice that as I went through the trays that they were getting dirty looking and discolored sooner and sooner. I started soaking them in Hydrogen peroxide after reading that 30 minutes or more would help clean the trays. When I had the tech take the impressions she said I would have to wear the current set, number 29 for another 3 weeks, which turned into 6 weeks by the time they received the new set of 24. I was concerned at that point about the bacteria and was soaking the trays every day. If the dental practice had been taking care of me properly some of this may have been avoided, but now after reading the stories of suffering and pain at this and several other sites, that I will not be going on with the treatment. It was a foolish idea I suppose to think that a medical professional would have my best interests at heart. The treatment cost $5,175, which I am of course still paying on. :( Hopefully the dentist will give me some sort of refund and remove the attachments. Am going in tomorrow. Wish me luck.

• LESLIEMay 26, 2017 at 1:51 am

  Shortly after beginning to use Invisalign, I got a rash around my mouth which has now spread to a few other areas of my face, including under my right eye and on the outside edge of one nostril. Thinking it might be an allergy to the plastic, I asked my dentist to get an ingredient list for the product. Approximately two months into wearing the Invisalign trays, my hair started falling out. Rel[Show More]Shortly after beginning to use Invisalign, I got a rash around my mouth which has now spread to a few other areas of my face, including under my right eye and on the outside edge of one nostril. Thinking it might be an allergy to the plastic, I asked my dentist to get an ingredient list for the product. Approximately two months into wearing the Invisalign trays, my hair started falling out. Related? Today I went to my allergy doctor who said I was allergic to the Invisalign trays.

• JeanetteApril 2, 2017 at 2:56 pm

  I haven't had Invisalign yet, but my dentist is encouraging me to get...and I'm doing my research on teeth, jaw, and joints...I need to straighten my teeth because they are shifting and they are interfering with my joints, ie locked hip, and effecting my walk. So...wow I'm really glad I came into this website, now I'm at a conundrum... Anyways, I ran into this website online: Ask for an "Aligner [Show More]I haven't had Invisalign yet, but my dentist is encouraging me to get...and I'm doing my research on teeth, jaw, and joints...I need to straighten my teeth because they are shifting and they are interfering with my joints, ie locked hip, and effecting my walk. So...wow I'm really glad I came into this website, now I'm at a conundrum... Anyways, I ran into this website online: Ask for an "Aligner 0" to go back to "normal" for those having physicial issue with the change in teeth position...You can read it here. https://www.realself.com/forum/invisalign-the-worst-mistake-my-life

• JamieMarch 15, 2017 at 12:47 pm

  I began Invisalign last year. About three weeks in my mouth and throat started to burn. I contacted my dentist and he assured me be had never heard of this before. I asked him if possible allergic reactions have been reported he said no. My mouth continued to get worse, then I got what seemed like the flu, migraines, foggy thinking, blurred vision, fatigue, stomach issues, lymphoids swollen and my[Show More]I began Invisalign last year. About three weeks in my mouth and throat started to burn. I contacted my dentist and he assured me be had never heard of this before. I asked him if possible allergic reactions have been reported he said no. My mouth continued to get worse, then I got what seemed like the flu, migraines, foggy thinking, blurred vision, fatigue, stomach issues, lymphoids swollen and my hair started to fall out. All of these symptoms are still happening. I have contacted Invisalign and they said they will change the trays to the hypoallergenic trays well it's still happening. I have been on antibiotic after antibiotic, mouth wash and even got referred to an oral surgeon. The only time it gets better is when I do not weare my Invisalign. I spent a lot of time, money and illness on this. I'm so close to being done but I can't deal with feeling this way. I'm a single mom with two special needs children. I don't want to feel this way I want my life back.

• DeannJanuary 13, 2017 at 12:19 am

  It's not just invisalign you need to worry about, learn more here: http://www.welcometodds.com/the-empowered-patient

• mariaDecember 16, 2016 at 3:27 pm

  I posted a comment at 19th july 2016 about my nightmare with invisalign retainers. I had also a hard time getting an innofensive report about the symptoms I had when using the product. Finally I was given hypoalergenic retainers in the 5th of December.I falled immediatly in bed with flu ( coincidence) and at the second week my face was a furnace of skin rashes , swoolen eyes, itchy neck and fever[Show More]I posted a comment at 19th july 2016 about my nightmare with invisalign retainers. I had also a hard time getting an innofensive report about the symptoms I had when using the product. Finally I was given hypoalergenic retainers in the 5th of December.I falled immediatly in bed with flu ( coincidence) and at the second week my face was a furnace of skin rashes , swoolen eyes, itchy neck and fever.Conclusion: The hypoallergenic retainers are also heavily toxic.

• MARTINDecember 15, 2016 at 4:34 pm

  My Dentist recommended Invisalign for TMJ my results have negative My bite has not been corrected and have been in severe pain

• JeanDecember 15, 2016 at 2:59 am

  I had a reaction to the regular trays of Invisalign.. not being able to swallow! I got the hypoallergenic ones and didn't have that problem. Although my hair has been coming out excessively!! I've worn these for 2 years now and after every test done with nothing coming back I'm finally wondering if hairloss is from these Invisalign?!? I'm scheduling to have regular braces out on. I'm desperate for[Show More]I had a reaction to the regular trays of Invisalign.. not being able to swallow! I got the hypoallergenic ones and didn't have that problem. Although my hair has been coming out excessively!! I've worn these for 2 years now and after every test done with nothing coming back I'm finally wondering if hairloss is from these Invisalign?!? I'm scheduling to have regular braces out on. I'm desperate for my hair back and this is my only option left

• MARTINDecember 15, 2016 at 1:14 am

  My Dentist recommended Invisalign for TMJ my results have negative My bite has not been corrected and have been in severe pain

• JennaDecember 1, 2016 at 9:02 am

  I am floored! I am a dental hygienist. I have worked in dental since I was 17 years old and simply stocking rooms, and am now 42. It's all I know, professionally. But, as I sit here, in bed, at 2am, with super swollen lips, I am in total disbelief! Here is my story. The orthodontist that we refer our patients to was so kind as to offer to realign my teeth for me, February, 16'! Note: After a fir[Show More]I am floored! I am a dental hygienist. I have worked in dental since I was 17 years old and simply stocking rooms, and am now 42. It's all I know, professionally. But, as I sit here, in bed, at 2am, with super swollen lips, I am in total disbelief! Here is my story. The orthodontist that we refer our patients to was so kind as to offer to realign my teeth for me, February, 16'! Note: After a first, successful round of Invisalign in 2003, followed by 9 years of wearing Invisalign retainers at night, religiously, and WITHOUT any side effects, my retainers had broken. After about a year and a half of not wearing them, my teeth had shifted, considerably, which brings us to today. Right about the time I received my first set of trays, in February of this year, I began to have a significant occurrence of hives. Full body, head to toe. I immediately began taking antihistamines, Benadryl, Zyrtec, Allegra, alternating. Had no idea, till this very night, that this could be from Invisalign!!! My hives were so intense that if I skipped even one day of antihistamines, I'd wake with an entire body full of raised, burning, itchy hives, ALL OVER. Because my insurance is horrible, and specialists are expensive, I chalked them up to seasonal allergies (that I had also experienced during a majorly stressful time in my life, 16 years ago, also resulting in hives), so, I continued to treat my symptoms with antihistamines. However, the seasons have changed, and I am still medicating, since February! Am still medicating, to this very day! Now, this lip swelling thing has been off and on, and getting progressively worse, throughout all of this, but I hadnt connected it (till tonight) to the retainers. I thought it was my lip balm. Thought, maybe, the face masks that we wear at the dental office? So, I have discontinued use of both of those things, for about a month, now. (Wearing a face shield, instead of a mask, while treating patients). No recent swellings of my lips, so I hoped I had solved the problem. Till tonight. Put my new retainer in, around 9pm, tonight (tray #3 of 7, for this newest 'revision'), and just woke with a hugely swollen lip, swollen tongue (both, rt side), and extreme tightness in my chest! So, I began to search the Web to see if there were any others out there, like me, with this same experience. (Imagine my surprise). And, yes, I also have been having inflamed lymph nodes in my neck (thyroid area) and a few, the size of golf balls, a few months ago, in the back of my neck! Chalked those up to a history of cat dander allergy, or seasonal stuff?! I am astounded that after reading all of your posts, (there are many!), these crazy symptoms are definitely related, and due to the Invisalign trays!!! It all makes sense now! I am in shock. And, I must say, a bit embarrassed, that I didn't connect all these dots till now! Thank God for the Web and for all you amazing people that took the time to share your stories. Forgot to add that my lips have also been significantly dry and burning, lately. And, with removing lip balms, of any kind, from my routine, they have felt even worse! So, now what? Going to call my orthodontist as soon as the sun is up!!! Oh, and I'd better get these retainers out, stat! Sincere thanks to you all!

• DaniellaNovember 15, 2016 at 3:06 am

  I got a plastic retainer my lips swelled I had seizures and emergencies now im disabled in college wondering how I can find enough to eat.

• TPSeptember 20, 2016 at 1:24 pm

  I have had my Invisalign since Jan. of 2016 and I'm at the refinement stage now. I would be done, but have to do a few more tweaks. I have had the worst migraines of my life during the course of this treatment and I thought it was stress related. I had to be put on prescription migraine medication and even still when I get them I am paralyzed with pain. I truly believe these retainers have caused [Show More]I have had my Invisalign since Jan. of 2016 and I'm at the refinement stage now. I would be done, but have to do a few more tweaks. I have had the worst migraines of my life during the course of this treatment and I thought it was stress related. I had to be put on prescription migraine medication and even still when I get them I am paralyzed with pain. I truly believe these retainers have caused it. I've also been dizzy, light headed and get extreme motion sickness. I never used to experience any of these things until a couple months into my treatment. They have to be related. Looking forward to getting these things out and detoxing/cleansing. Hopefully symptoms will resolve when I do.

• BunSeptember 5, 2016 at 10:12 pm

  Hi There! I had most of the symptoms in the beginning, but I noticed after a month of suffering in my bed from fever, headaches, servere cough, swollen throat, low energy, tired, and allergies, I thought it was from food poisoning, since a friend and son had it. I have never been that sick in my life, I thought maybe it was in the air. Someone mentioned the loss of taste. I have that with the[Show More]Hi There! I had most of the symptoms in the beginning, but I noticed after a month of suffering in my bed from fever, headaches, servere cough, swollen throat, low energy, tired, and allergies, I thought it was from food poisoning, since a friend and son had it. I have never been that sick in my life, I thought maybe it was in the air. Someone mentioned the loss of taste. I have that with the loss of smell. I now have this strange smell and it's hard to enjoy food. It's like a cheesy/chemical taste and smell, its stronger depending on my surroundings, like smoke the smell gets worse. I also went from 145-150 lbs to now 121 Ibs. Later I had no idea what was causing everything. I thought maybe it was Cancer, Candida, or Diabetics. I wonder if it affected my mental health, since I was confused and had a hard time remembering things. I am so grateful to The Lord for directing me to look closer to the dangers of the trays. I'm surprised the dentist did not mention the hypoloallergic trays, or share other people's side effects, and share the chemical ingredients. I removed them three days ago, now experiencing itch and headaches. My ortho. office recommended a fluoride toothpaste: Colgate, PrevilDent 5000, which I will stop using as well, and go back to Tom's non-fluoride toothpaste, I heard fluoride is very bad. Dentists say use only a little bit, but if you brush your teeth more than twice a day, the fluoride adds up. Thank you all so much for your comments!!

• PhyllisJuly 24, 2016 at 5:08 pm

  I wore the Invisalign braces without issues for 1 1/2 of the 2 years that I was scheduled to use them. Gradually I started feeling "off" and it got to the point where my throat felt tight and I felt spacey and like I was having a panic attack. There was no reason to have a panic attack and they had never happened previously. I went to the fire station to have my vitals checked. Oxygen levels were [Show More]I wore the Invisalign braces without issues for 1 1/2 of the 2 years that I was scheduled to use them. Gradually I started feeling "off" and it got to the point where my throat felt tight and I felt spacey and like I was having a panic attack. There was no reason to have a panic attack and they had never happened previously. I went to the fire station to have my vitals checked. Oxygen levels were fine, heart rate up a bit and having PVCs - they suggested I see an allergist. I made it home; something told me to google Invisalign and allergic reactions. I took out the braces and took a Claritin. Started to feel more normal after half hour or so. Left the braces out, had to take the Claritin daily (still do even though the braces have been out now for many months) plus additional vitamin C for the anti histamine effect. Did see allergist, explained what had happened. She did some tests; ended up doing a nebulizer treatment to increase lung air flow. A blood tryptase level came back elevated; this can be associated with an increased risk of severe allergic reactions. My younger sister, who gets allergy shots weekly, also tested with an elevated tryptase level. Interestingly enough, I had additional labs, IgE and RAST testing and they all came back completely NEGATIVE. No food or environmental allergies (they don't test for chemicals like whatever is used in the braces). My orthodentist had a retainer made for me, stainless steel with some type of plastic (different from the invisalign material) for the part that is in the back of the retainer. Within minutes of inserting the retainer my throat tightened so I yanked it out and immediately took 6 additional grams of vitamin C. Symptoms eased after half hour or so. When I read online about some other people who had had reactions, they commented about the sense of panic and anxiety; some had local swelling or blisters. No one had warned me about any of this before I started. I now notice on the TV commercials for the Invisalign there is a caution about possible rare allergic reactions. Too bad I couldn't be refunded for the unused trays. This treatment is EXPENSIVE.

• LauraJuly 21, 2016 at 8:27 pm

  Has anyone experienced feeling overheated? Excessive sweating? Difficulty breathing or asthma like symptoms? Since I started Invisaligns a year ago I have excessive sweating day and night. I have never had trouble breathing before I started wearing Invisaligns. Then I see this site. I will read the MSDS sheet on the plastic. Why wasn't I given any material that would warn me of this?

• GinaJuly 8, 2016 at 7:58 pm

  I started wearing Invisalign in October 2015. I experienced dry lips from the very start, but it was fall and the furnace was starting to run so I thought it was just that the house was dry. Now it is July 2016 and my lips are still dry. If that were my only problem, I would be fine with it. However, I have been getting recurrent cold sores. These cold sores, if that is really what they are, don't[Show More]I started wearing Invisalign in October 2015. I experienced dry lips from the very start, but it was fall and the furnace was starting to run so I thought it was just that the house was dry. Now it is July 2016 and my lips are still dry. If that were my only problem, I would be fine with it. However, I have been getting recurrent cold sores. These cold sores, if that is really what they are, don't respond the Abreva or Lysine like previous colds sores did. I have also gotten them within a few hours of having impressions taken for the Invisalign. That got me to wondering if the cold sores and dry mouth was caused by my Invisalign. I did a search and found this site. I am on my second set of aligners and about two and a half months away from finishing so I might just try to tough it out. I am hoping that the retainer won't cause the same problem. At least I will only have to wear that at night. Does anyone know if the retainer is made out of the same material?

• DanaJuly 5, 2016 at 9:46 pm

  I can’t get a refund because of no official doctor’s report? What if people don’t have a health insurance like me? I should pay few thousand dollars by cash to find out the cause of the symptoms, (I’ve already talked with friends and doctor friend, many people they paid few thousand dollars with health insurance to see the doctors…) If the return money is only $250.00, I can’t spend more t[Show More]I can’t get a refund because of no official doctor’s report? What if people don’t have a health insurance like me? I should pay few thousand dollars by cash to find out the cause of the symptoms, (I’ve already talked with friends and doctor friend, many people they paid few thousand dollars with health insurance to see the doctors…) If the return money is only $250.00, I can’t spend more than $250.00 dollars by cash, right? Please let me know how much will be the refund, then maybe I will go to see the doctors. If you have an official letter from clear correct representatives, could you forward me that? or Can I talk / send a letter to clear correct directly? BTW, can you replace the trays with hypoallergenic version? Thank you, Young

• JenniferJune 27, 2016 at 4:43 pm

  I had a similar reaction within minutes of getting Invisalign . My lips and gums burned , I was dizzy , had flu-like symptoms( sore throat , achy , chills ) , and my neck got stiff . I went to the ER and asked me what I had today and I told them Invisalign was done and they said it was an allergic reaction . Very scary !!! Is anything being done about this ?

• mariaJune 19, 2016 at 8:37 pm

  I've been using Invisalign bracets since july 2015.I was stuck in bed for almost 2 month with severe abdominal inflammation and the cause was not found. I was diagnosed with burnout in december and further in february. In may I stopped working already taking antidepressants.I could not move.Dizziness, foggy vision, strong headaches, chronic fatigue, pain in the bones and veins were some of the sym[Show More]I've been using Invisalign bracets since july 2015.I was stuck in bed for almost 2 month with severe abdominal inflammation and the cause was not found. I was diagnosed with burnout in december and further in february. In may I stopped working already taking antidepressants.I could not move.Dizziness, foggy vision, strong headaches, chronic fatigue, pain in the bones and veins were some of the symptoms. I only associated that with Invisalign after reading exactly the same reports in internet. After quitting Invisalign I recovered.

• ElleApril 21, 2016 at 3:34 am

  I decided to get the Invisalign Express 10 (five trays over 10 weeks) for some minor shifting that's occurred as I've gotten older (I had braces in middle school back in the 80s). Although I did experience allergic reactions, mine were isolated to my mouth area alone, specifically my lips, corners of my mouth and the skin surrounding my lips. It definitely caused some pain and discomfort, but it w[Show More]I decided to get the Invisalign Express 10 (five trays over 10 weeks) for some minor shifting that's occurred as I've gotten older (I had braces in middle school back in the 80s). Although I did experience allergic reactions, mine were isolated to my mouth area alone, specifically my lips, corners of my mouth and the skin surrounding my lips. It definitely caused some pain and discomfort, but it was so unsightly and very noticeable. The dry mouth with wearing the trays was beyond annoying, so I initially thought the chapped lips and mouth irritation was a result of that. One mouth corner was really irritated...I thought I was getting a cold sore, but never happened. Took some Acyclovir just in case, no improvement. Also took Lysine supplement and applied Lysine ointmemt, also no help. My lips felt hot, and I had a red ring on the skin surrounding my mouth, which also felt hot. I could always tell when the redness got worse without looking because of that hot feeling. One corner of my mouth was just raw. I was afraid to open my mouth that much because the skin felt so tight, I thought it would crack and bleed. My whole mouth area just hurt (but not inside...no sores, no swollen tongue). I also don't recall any coldlike symptoms, but I also have allergies so maybe it didn't register with me. I Googled for dry mouth/irritation with the Invisalign for suggestions and learned about the history with allergic reactions to invisalign and that there was a hypoallergenic version. I hit Invisalign up on Twitter asking for advice bc I was having a reaction. They responded quickly, told me to stop wearing the trays, contact my dentist and follow a link to fill out infomercial they could contact me directly. Had a dentist appnt a cple days later and showed him the problem. Invisalign replaced all of my trays with the so-called hypoallergenic tryas. Same thing happened within 8 hours of wearing those. They said they have, one more option/type of tray and I'll get those in a week. BUT, this 3rd option is simply the first or at least a previous version. And the only difference b/t the 1st trays I got and the "hypoallergenic" is a slightly different polyurethane. At least Invisalign has offered to give me a full refund if this 3rd set doesn't work. Still sucks bc my teeth have already moved and my night guard no longer fits and it's $800 for a new one. I wish I never started with Invisalign at all. The redness still hasn't fully healed and still often gets inflamed on one side, and that's after only having the 2nd set in for 8 hours over the past three weeks or so. Starting to think it will never go away. The Rx my dermatologist give me for it is over $300 (not covered by my insurance...and it cost me a $70 co-pay) so I can't afford to fill the script.

• marionMarch 29, 2016 at 10:20 am

  my name is marion i had the same problem with invisalign the orthodontist that i had did not care his name was gersh i went throught the treatment it has been a year and i am still having problems excess saliva can any one helpme i hope you can contact me so we can talk

• debbieMarch 14, 2016 at 8:25 pm

  got my first tray on March 3rd.A few hours after wearing the first invisalign retainers I felt my tongue burning.My lips were swallen and had blisters on my tongue and lips. I wore the retainers about 32 hours thinking that I might be a crying baby.The cement put on my teeth tore my skin all over. the sharp edges of the retainers cut my skin and tongue or so I thought. Went to see another dentist [Show More]got my first tray on March 3rd.A few hours after wearing the first invisalign retainers I felt my tongue burning.My lips were swallen and had blisters on my tongue and lips. I wore the retainers about 32 hours thinking that I might be a crying baby.The cement put on my teeth tore my skin all over. the sharp edges of the retainers cut my skin and tongue or so I thought. Went to see another dentist who made the cement bumps smoother and cut part of the sharp edges of the retainers. I wore the retainers for a another day thinking it would be better which never happened. Called my Orthodontist and he reassured me things would be all right. Could not stand it and took the retainers out for a few days. The symptoms subsided a lot but did not completely disappeard. That was when I thought that I have an allergic reaction to the retainers. After the symptoms calm down I started wearing the retainers again for about 3 days which were a nightmare. All the symptoms from before and many others appeared,like head aches,ears aches,jaws aches,nausea,stomach cramps and diarrhea ,mouth ulcers.dried mouth,dizziness. I stopped wering the retainers for 2 days and the symptoms got a bit better. Called my Orthodontist again and he told me to wear the retainers in intervals of 2 hours to get used to them and that I should see him to try to fix the retainers. When I told him that I have an allergic reaction he said that it is impossible because my retainers are Hypoallegenic. I put back the retainers back on my teethe and the symptoms were back within a short time like minutes. I am so mad at the orthodontist for dismissing my complains. I am going to see him in a few days and try to get a refund for my money.Without any doubt I am not going to wear these invisalign retainers.

• XiomaraFebruary 9, 2016 at 11:37 am

  Hello, Can't sleep 3am. I started using invisiline in Oct 2015 just before we went on a cruise. Three days in I woke up with a swollen lip. Since my immunity is low I thought I had been parting to much and my body could not take it. A few months later a woke up with swollen lymph nodes and felt like a cold and with a swollen lip. I have small bumpd on my lips and they also peel. I through maybe a[Show More]Hello, Can't sleep 3am. I started using invisiline in Oct 2015 just before we went on a cruise. Three days in I woke up with a swollen lip. Since my immunity is low I thought I had been parting to much and my body could not take it. A few months later a woke up with swollen lymph nodes and felt like a cold and with a swollen lip. I have small bumpd on my lips and they also peel. I through maybe a was having as reaction to alcohol, stress, starting my cyclkr or oils that I started using. A few weeks ago I call my orthodontist and told them about my lips situation and they stated that the trays did not cause my symptoms that I have cold sores. After reading this took of my trays.I will be going to the office and talking to my orthodontist. My teeth are fine the reason I was wearing them is because I have tmj. Thank you so much for this site.

• NaokaJanuary 6, 2016 at 7:07 am

  I started my invisalign december 16th, 2015. I first noticed pain in my back so I assumed it was my lungs. Since it was winter time I figured it was just a bug I had caught. Four days into my invisalign the pain in back spread to my chest. I started having a shortness of breath and I also felt completely exhausted even though I was not tired. That same day I noticed a swollen lymph node under my a[Show More]I started my invisalign december 16th, 2015. I first noticed pain in my back so I assumed it was my lungs. Since it was winter time I figured it was just a bug I had caught. Four days into my invisalign the pain in back spread to my chest. I started having a shortness of breath and I also felt completely exhausted even though I was not tired. That same day I noticed a swollen lymph node under my armpit and tiny sores on my gum line, however it wasnt where the invisalign touched. I then googled mouth sores associated with invisalign and found this website! I immediately took them out. Most of the symptoms have subsided but I still feel like there is something stuck in my throat and chest. I seen my ortho today (Jan 5 2016) and he assures me that it is not invisalign but I dont believe him and Im not willing to chance it again like he suggest I should.

• BrandyDecember 29, 2015 at 10:46 am

  I started Invisalign and shortly after started having shortness of breath and gum irritation. Once I reached my 3rd Trey or so I noticed a big purple spot was forming on my upper lip as well as my gum where the Invisalign touched. I was concerned as to what may have caused it. I immediately thought it may be my Invisalign but once I mentioned it to my orthodontis, he dismissed the idea of it being[Show More]I started Invisalign and shortly after started having shortness of breath and gum irritation. Once I reached my 3rd Trey or so I noticed a big purple spot was forming on my upper lip as well as my gum where the Invisalign touched. I was concerned as to what may have caused it. I immediately thought it may be my Invisalign but once I mentioned it to my orthodontis, he dismissed the idea of it being an allergic reaction so I went to the doctor and they ran many tests which came back normal. I demanded they send me to a skin specialist and they diagnosed me with dermatitis which is an allergy/allergic reaction. She advised I stop using Invisalign and after a month of discontinuing my huge purple spot on my lip has faded tremendously to where I don't have to wear lip stick to cover it. But it is still slightly noticable. Not to mention my testh are now Crooked because I had to doscontinue. So much money wasted I pray they make this right by refunding my money or something this is insane how much stress I have gone through trying to find out why I am having a hard time breathing let alone have a huge purple spot on my upper lip that can't be disguised with the darkest lip stick smh dot ever do Invisalign so not worth it!! I may have to sue this is insane all these complaints and I wasn't even notified that there are potential health risks associated with Invisalign.

• CaraDecember 6, 2015 at 4:11 am

  Luckily I stumbled upon this while searching if the marble size ball under the inside of my lower lips is caused by invisalign. I'm so upset. I have not had chronic chapped and peeling lips since I was 20. I'm 39 now. Also, being someone who practices yoga I like to do deep breathing exercises... not since starting Invisalign nearly 2 months ago. Today while sitting at my desk I felt a marble size[Show More]Luckily I stumbled upon this while searching if the marble size ball under the inside of my lower lips is caused by invisalign. I'm so upset. I have not had chronic chapped and peeling lips since I was 20. I'm 39 now. Also, being someone who practices yoga I like to do deep breathing exercises... not since starting Invisalign nearly 2 months ago. Today while sitting at my desk I felt a marble size lump inside the skin between my lower lip and chin. I freaked out! I just took my trays out, and will not do anything else until I speak with my Orthodontist. Why doesn't everyone get Hypoallergenic Invisalign? This makes no sense!

• ShirleyNovember 27, 2015 at 4:46 am

  I didn't know this site existed until I google Invisalign and sore throat. I have been wearing Invisalign for six weeks now. Every seven days I put in a new tray. The fifth week I noticed a different taste on the plastic. The next day my lips were swollen tongue swollen throat extremely sore face itch tongue numb face swollen and inside my mouth was very red and sore and I was nauseous couldn't ea[Show More]I didn't know this site existed until I google Invisalign and sore throat. I have been wearing Invisalign for six weeks now. Every seven days I put in a new tray. The fifth week I noticed a different taste on the plastic. The next day my lips were swollen tongue swollen throat extremely sore face itch tongue numb face swollen and inside my mouth was very red and sore and I was nauseous couldn't eat. Went to the Doctor he treated me for allergies. Four days later it flared back up. again I was treated for allergies. Tuesday l put in my sixth set Wednesday I was back been treated for allergies again. I prayed went to Walmart bought me some Lysine for my lips. I went home took the Invisalign off and soaked them in in some dawn dish washing detergent drank me some warm lemon water swished some warm salted water around in my mouth several times put some ice on my lips then I put the Invisalign back in my mouth after an hour. Today is Thanksgiving. I have no problem eating and I have no symptoms. I will wait until Saturday to see if what I did work since I flare up every four days. Plastic never been good not even with bottle water. I'm drinking plenty of water because those Invisalign are full of bacteria in the mouth. Glad I found this site!

• JodiNovember 16, 2015 at 9:49 pm

  I cannot believe that I just found this site. I joined the Invisalign bandwagon in 2012 and had many issues with the trays cutting the inside of my mouth. However, my plight escalated to the extreme. After almost 1 1/2 years of the Invisalign saga of discomfort, I finally said enough is enough! My tongue was killing me 2 months before I stopped. I believed it to be an irritation from my tongue rub[Show More]I cannot believe that I just found this site. I joined the Invisalign bandwagon in 2012 and had many issues with the trays cutting the inside of my mouth. However, my plight escalated to the extreme. After almost 1 1/2 years of the Invisalign saga of discomfort, I finally said enough is enough! My tongue was killing me 2 months before I stopped. I believed it to be an irritation from my tongue rubbing up against the trays on the left side of my mouth. However, after we stopped the treatment, my tongue persisted to hurt immensely. I ended up going to an orthodontist (a dentist applied the Invisalign), to help put my teeth back in place and hopefully stop the discomfort in my tongue by doing that. However, after being n braces for 15 months, trying different tweaking methods to try to give me some relief, there has been only a little relief. My tongue burns constantly. I went to an ENT specialist to check my tongue and he said it was perfectly healthy to the eye. I went to my dentist and he said the same thing about the health of my tongue. BUT, I feel the continuous friction of the rubbing up against my teeth. Finally, my dentist today believe that there is some nerve damage caused by the invisalign that is giving me the burning sensation. What to do now? I am still searching for that answer.

• MariluOctober 26, 2015 at 5:07 am

  I started Invisalign in May of this year, right after using the tray I started having sore throat , dry chapped lips, swollen lynfo, I felt like I'll, I was feeling nausea and once during a meeting for work I had to run to the bathroom as I felt extremely nauseated and felt I had to throw up. Well the worse has still to come, my immune system started reacting to many things and I suddenly also dev[Show More]I started Invisalign in May of this year, right after using the tray I started having sore throat , dry chapped lips, swollen lynfo, I felt like I'll, I was feeling nausea and once during a meeting for work I had to run to the bathroom as I felt extremely nauseated and felt I had to throw up. Well the worse has still to come, my immune system started reacting to many things and I suddenly also developed metal allergies and I was feeling metal in my mouth and was giving me bad allergic reaction as my throat felt like flooding up so I immediately was getting Benadryl. Well after 2 weeks I started understaffing that it was Invisalign that was causing this, so I tried to not wear the trays for about 3-4 days and my symptoms were great,y improving so I called my doctor and he said that it is rare but that the have hypoallergenic ones, I absolutely did not want to try them, I was dine with this. Well the main problem is that it seems that the plastic trays intoxicated my body and my immune system got more sensitive and started reacting to almost everything which brought me several times to the hospital and has to take cortisone and other medicines to call this down. After almost 5 months of stopping using the Invisalign I still have the consequences of the 2 weeks I have been using them. Why they do not give the hypoallergenic ones since the beginning? What there is no warning about these reactions? Invisalign is a scam, I would not suggest it to no one. I think it would be right to sue them, it is not correct for us to go through something horrible like this. Good luck to everybody!!

• PNOctober 22, 2015 at 7:04 am

  I only lasted 5 days. I also wish I had seen these comments beforehand. I was in excruciating pain by my 5th day. The burning sensation in my mouth and tongue was intolerable. I lost 5 lbs in 4 days because eating was so painful. By the 5th day, I was unable to speak. I had researched Invisalign prior to getting them but had never heard of allergic reactions or the burning tongue reaction. I ended[Show More]I only lasted 5 days. I also wish I had seen these comments beforehand. I was in excruciating pain by my 5th day. The burning sensation in my mouth and tongue was intolerable. I lost 5 lbs in 4 days because eating was so painful. By the 5th day, I was unable to speak. I had researched Invisalign prior to getting them but had never heard of allergic reactions or the burning tongue reaction. I ended my treatment on the 5th day and was so relieved to be free of the pain. My entire system felt off kilter and is still recovering. How sad that I spent $3,800 to endure 5 days of pain. Absolutely regret my decision, however, my dentist may refund a small portion.

• LaurieSeptember 28, 2015 at 11:13 pm

  I started invisalign in August. I wish I would have read these stories sooner. I had them in and the next day I started getting a tingling in my lips , they would swell, peel and are so dry. I was not able to to go past the 2nd tray. I was never warned that some people can have an allergy to them. They said to stop if I wanted and they would order hypoallergenic tray for me. THERE ARE NO HYPOALLER[Show More]I started invisalign in August. I wish I would have read these stories sooner. I had them in and the next day I started getting a tingling in my lips , they would swell, peel and are so dry. I was not able to to go past the 2nd tray. I was never warned that some people can have an allergy to them. They said to stop if I wanted and they would order hypoallergenic tray for me. THERE ARE NO HYPOALLERGENIC INVISALIGN. The minute I put the so called hypoallergenic trays in I felt the same thing immediately. So I took them out and went to an allergist. he said it may take 1 to 3 months for the symptoms to go away. So Called the dentist and I was told that they are not really hypoallergenic but run through again to get rid of more of the product . I would have never put them in my mouth again if I had known. So pissed. My lips swell, burn , tingle and peel it is 2 months now.

• BarbJune 11, 2015 at 12:43 am

  Hi everyone here! Well, first, let me say I WISH I would have found and read this site PRIOR to Invisalign. I've been in treatment for breast cancer and after the ordeal of that was mostly done, stupid me... I decided to straighten my teeth. I do have to say, my teeth were not very crooked and was not noticeable. Knowing I would not be able to do regular braces, I thought I'd try Invisalign. [Show More]Hi everyone here! Well, first, let me say I WISH I would have found and read this site PRIOR to Invisalign. I've been in treatment for breast cancer and after the ordeal of that was mostly done, stupid me... I decided to straighten my teeth. I do have to say, my teeth were not very crooked and was not noticeable. Knowing I would not be able to do regular braces, I thought I'd try Invisalign. I spoke with my dentist and my orthdontist and they thought this would work. When I was fitted for the trays, I ended up having 8 upper and 14 lower "attachments" put on some of my teeth. In case any of you don't know what this is, it's little dots of dental cement that they put on the teeth so the Invisalign moves those teeth. I started my trays approximately 6 weeks ago. The next day, the inside of my mouth was bleeding, very sore, inside of my lips was starting to swell, and it felt like the trays were cutting me. I called the orthodontist immediately and went back in. He trimmed the trays and we thought everything was fine. Over the next few days, my lips hurt, mouth was bleeding on and off, and as many of you mentioned, I started getting a sore throat and cough. I called the orthodontist again. Another trip in and more trimming and "adjusting" the trays. Also the attachments were cutting the inside of my mouth. This routine continued through the 1st two weeks. Then I was to go to tray # 2. I started tray # 2 and more of the same painful symptoms and another trip to the orthodontist. He also filed down some of the attachments. Two weeks ago I started tray # 3. The same day my mouth began to hurt so bad I thought something serious was wrong with me. And also, more of that cough that won't go away. I called the orthodontist and he had gone on vacation. His office said to leave tray # 2 in for now until he could look at my issues. Last weekend, my tongue, which has been uncomfortable the entire time, began to swell on one side. I removed the trays and left them out of my mouth. My tongue has a "boil" or pimple type area on the under left side. It is finally beginning to calm down but is still very sore and PAINFUL! Also it is bleeding on and off. I saw the ortho today and he said it's rare to have a reaction to the trays but that some people do. I told him I've not had the trays in for 4 days and my mouth is finally beginning to calm down but still hurts. He took pictures of my tongue to show the Ivisalign representative so they can document my reaction. As far as I know, they are going to give me back the money I've already paid - $4,000. I wish the dental doctor's would completely explain that you can have more medical problems from Invisalign. If I had know this was all possible I would have NEVER done this. I'm just glad I did not continue using this product and this has only been 6 weeks! I'm so sorry everyone here has gone through such pain!

• LisaJune 6, 2015 at 5:49 am

  I embarked on the invisalign journey in february of this year. I opted for the propel treatment to expedite the length of treatment. This meant I was changing my trays on average every 5 days. Within a week of wearing invisalign I developed a severe sore throat, ear pain like I had never experienced (think ice picks being jabbed into my ears) and a high fever. I chalked it up to strep throat being[Show More]I embarked on the invisalign journey in february of this year. I opted for the propel treatment to expedite the length of treatment. This meant I was changing my trays on average every 5 days. Within a week of wearing invisalign I developed a severe sore throat, ear pain like I had never experienced (think ice picks being jabbed into my ears) and a high fever. I chalked it up to strep throat being as how I am a nurse and work in an emergency department. My primary care physician wrote me a prescription for antibiotics. I finished the course of antibiotics and the sore throat persisted along with the ear pain and seriously swollen lymph nodes, hard as rocks. I revisited my pcp several times over the following two months. I mentioned to the Orthodontist in each visit about the sore throat and the ear pain. He never made a suggestion or inquired about my symptoms. I was given three additional rounds of different antibiotics and steroids along with allergy medications by my PCP. I was run down, short of breath, an tired of being in pain. It was literally wreaking havoc on my life. I finally made a trip to an ENT, only to have a horrible scope pushed through my nares and down into my throat all to find nothing. Approximately three months into treatment I considered that it might just be the invisalign. I didn't want it to be, I desperately wanted to perfect my smile. I took the invisalign out and discontinued using for three days. Symptoms were subsiding. I called the ortho to have the buttons removed within that same week. My symptoms went away instantly. However, Im still out the already $4k I paid for the treatment, and an additional $1500 chasing other doctors around to get to the bottom of my symptoms. I am a nurse and used my own common sense to determine I was having an allergic reaction when an orthodontist, general physician and an ear nose throat specialist could not. So frustrating. I will strongly advise against this product after reading everything I have regarding its composition and health hazards.

• SandyMay 18, 2015 at 5:31 pm

  I had my Invisalign for 10 days and I've been having this terrible coughing that kept me up and awake all night. This started immediately the day after I put my first trays on. I had sore throat, coughing, mouth ulcer, itching in my mouth, tongue and throat, feeling of burnt tongue, and wheezing or asthma-like symptoms. Three days after my cough started, I consulted my PD and he prescribed me a [Show More]I had my Invisalign for 10 days and I've been having this terrible coughing that kept me up and awake all night. This started immediately the day after I put my first trays on. I had sore throat, coughing, mouth ulcer, itching in my mouth, tongue and throat, feeling of burnt tongue, and wheezing or asthma-like symptoms. Three days after my cough started, I consulted my PD and he prescribed me a Z-pack which I took the full course. On top of that I am taking Claritin and Flonase for my allergy. I was a little suspicious about the Invisalign so I googled it and check out for side effects. I found a websites that tells of two possible allergic reactions from wearing Invisalign such as sore throat and coughing, both of which I have experienced. So I contacted my dentist about it and he told me to stop using the aligners for a day or two. But then I wasn't too sure if it's the aligners that caused my terrible coughing or just the pollens. So I told him I'm just going to tough it out coz I dont wanna go back to week 1 of using the aligners. But 10 days later and still on medications, the coughing didn't show any sign of improving. I still have the sore on the corner of my mouth, my tongue hurts, my throat itchy , I felt dizzy spells,. So I searched the net again for possible allergic reactions to Invisalign and voila, I found this website and read about all your comments and reactions! I was horrified to say the least. I didn't even wait to speak with my dentist. I took them off right away. As I write this comment, it is now 20 hours after I stopped wearing my aligners and I'm still coughing terribly with all the other issues that I mentioned I have.

• VALMay 7, 2015 at 8:56 pm

  It has been 3 days since I started with Invisalign. I have developed red welts up and down my neck and into my chest. My neck is very sore. I called after reading the sheet that was given to me that warned of adverse allergic reactions in some and was told not to continue wearing them. I have an appointment with the dentist on Monday and will see what will transpire but I will not continue wearing[Show More]It has been 3 days since I started with Invisalign. I have developed red welts up and down my neck and into my chest. My neck is very sore. I called after reading the sheet that was given to me that warned of adverse allergic reactions in some and was told not to continue wearing them. I have an appointment with the dentist on Monday and will see what will transpire but I will not continue wearing them. Thank you for these comments.

• RTMApril 29, 2015 at 8:07 pm

  This is so crazy! I started my Invisalign 3 weeks ago. After a week of having them in, I lost all sense of taste and my tongue feels like I burnt it. I also have a tingling/numb sensation on my tongue. I went to my dentist today and she feels like I could be having a reaction to the trays. Well duh! Now I'm reading about so many other people with similar if not worse symptoms! This is horrible! I'[Show More]This is so crazy! I started my Invisalign 3 weeks ago. After a week of having them in, I lost all sense of taste and my tongue feels like I burnt it. I also have a tingling/numb sensation on my tongue. I went to my dentist today and she feels like I could be having a reaction to the trays. Well duh! Now I'm reading about so many other people with similar if not worse symptoms! This is horrible! I'm sorry for all of us experiencing this and hope the horrible conditions go away soon!

• MissyMarch 2, 2015 at 6:59 pm

  People, obtain the material data sheet on Invisalign. It contains a toxic chemical called MDI used in polyurethane. It is hazardous /toxic to those exposed it. Will cause immune problems and slowed functioning. Read about it. Imagine it being in your mouth, saliva and enzymes breaking it down and into your tissues/blood through the port of entry of the mouth sores caused by the aligner trays. Com[Show More]People, obtain the material data sheet on Invisalign. It contains a toxic chemical called MDI used in polyurethane. It is hazardous /toxic to those exposed it. Will cause immune problems and slowed functioning. Read about it. Imagine it being in your mouth, saliva and enzymes breaking it down and into your tissues/blood through the port of entry of the mouth sores caused by the aligner trays. Company doesn't disclose hypoallergenic trays are available but they are. Request the MDS first and learn what is in the product. It's not "just plastic" that your dentist or ortho will tell you. Huge physical health risks.

• LauraJanuary 18, 2015 at 7:33 am

  My daughter was rip off by out dentist. By getting invisalign for her. I made a huge mistake by letting a regular dentist that not a orthodontist. On September 2014 she received a small blue tray. With her first tray only and the bottom tray did not even fit. That was a red flag right there he was showing her how to make the bottom tray fit. By putting two dental swabs on her bottom tray and where[Show More]My daughter was rip off by out dentist. By getting invisalign for her. I made a huge mistake by letting a regular dentist that not a orthodontist. On September 2014 she received a small blue tray. With her first tray only and the bottom tray did not even fit. That was a red flag right there he was showing her how to make the bottom tray fit. By putting two dental swabs on her bottom tray and where it ,until it losen it up to fit.I told his assistant she's 20 years old ad she not going to do that. I told her to ordr a new tray which they never did. She was told the next time you come in you will have a new tray. They always had a excuse why a new tray was not available. She went back 3 to 4 more times. Always the same story On Dec 2014. I realized he was cutting corners with my daughter. I told them how I felt and she's not coming back. I did my homework after that. It was not invisalign if it was it comes in a box with many sets of trays aligners. with her name on it. When my daughter stared crying in the car she was very upset she has to start all over. With either braces or invisalign somewhere else. It upset me so much to find out that all the ortho money was use all up from my insurance and my husband. And Next week she will have to start all over by a real orthodonist. And now I have to pay more money. Its not fair I'm fighting grievance at this moment . Not sure if I'm getting my ortho money back from both claims. I will sue him if I dont get my money back. He's a crook dentist he needs to pay for the damage he cause my daughter.Depression over this situation. He charges both insurance for the same treatment. One tray since September and on December when I spoke up. Why don't you ever have new trays for my daughter. He said because the holidays. Really since Sept 2014.

• LizJanuary 14, 2015 at 9:16 pm

  I started my Invisalign just before Christmas, and for the first 2 weeks all was well, but two days into the second set of aligners I began to feel very uncomfortable having them in my mouth, had two days of bad nausea then started to develop a dry cough that became almost constant. My tongue felt one afternoon as if I had burnt in but I couldn't think of anything I had eaten or drunk that was ver[Show More]I started my Invisalign just before Christmas, and for the first 2 weeks all was well, but two days into the second set of aligners I began to feel very uncomfortable having them in my mouth, had two days of bad nausea then started to develop a dry cough that became almost constant. My tongue felt one afternoon as if I had burnt in but I couldn't think of anything I had eaten or drunk that was very hot. I then experience two short panic attacks and woke one night sweating. I took the trays out the cough lessoned immediately, back in it started again. I agreed with my dentist to cease wearing them immediately two days ago until it is reviewed with the manufacturer. 36hrs of not wearing them and I am still feeling nauseous and sometimes start coughing and dry retching. I feel I must be having a reaction to something toxic. I am amazed that no allergy testing is not done on such an expensive product when clearly others are suffering as well and that if there is a hypoallergenic option why is this not offered at the outset? I am not sure what to do next.

• AliJanuary 3, 2015 at 6:53 pm

  I started my first set of trays last Tuesday. I was in-bed ill with terrible mouth pain for five days. My tongue was swollen, my throat was swollen and I felt like I had strep throat. I had watery eyes and I was sneezing. Incredibly, I just thought this was my body getting used to the trays. Then when I couldn't talk at all on day five due to intense tongue swelling which made it absolutely impo[Show More]I started my first set of trays last Tuesday. I was in-bed ill with terrible mouth pain for five days. My tongue was swollen, my throat was swollen and I felt like I had strep throat. I had watery eyes and I was sneezing. Incredibly, I just thought this was my body getting used to the trays. Then when I couldn't talk at all on day five due to intense tongue swelling which made it absolutely impossible to swallow and my tongue erupted in sores, I yanked those trays out and began to feel better pretty much within an hour. The sores are still healing, but I am myself again. Its the weekend so I can't contact my orthodontist. I payed almost $5k for these trays so he better have a solution! I started Googling Invisalign problems and I feel bad that in all my years of researching this product, I never once saw any mention of allergies and sores. I wish I had gone with regular braces at this point and am hoping my ortho recommends that as well. We will see what happens, but as it is, I will not be putting those poison pellets back in my mouth. Everyone trying to "tough it out" may be forcing your body to be on fight mode, which will lower your immune system and could trigger other illnesses. You have to be careful with allergies.

• JanetDecember 30, 2014 at 6:53 pm

  My son almost died from invisalign braces. It's been almost three years since he has had them in and he still has pain attacks, no appetite and has basically been forced to quit school as he is ill so much. Was the healthiest child before putting those poisonous things in his mouth. Dentist,doctors and even the ceo of align technologies and health Canada refused to do anything to help him If anyon[Show More]My son almost died from invisalign braces. It's been almost three years since he has had them in and he still has pain attacks, no appetite and has basically been forced to quit school as he is ill so much. Was the healthiest child before putting those poisonous things in his mouth. Dentist,doctors and even the ceo of align technologies and health Canada refused to do anything to help him If anyone is considering a case against them, I am the one to talk to as I have everything documented and am ready to sue..

• GayleDecember 23, 2014 at 3:44 pm

  As like many of the other stories on this forum, I too have all those symptoms. I just completed 14 months of Invisalign and two days after I got my retainers, I came down with the worst sinus headache ever. My right eye, jaw, ear, head, neck, teeth were all extremely sore. I thought I just had a really bad cold so persisted for about 2 weeks before heading to the clinic to get checked out. He sai[Show More]As like many of the other stories on this forum, I too have all those symptoms. I just completed 14 months of Invisalign and two days after I got my retainers, I came down with the worst sinus headache ever. My right eye, jaw, ear, head, neck, teeth were all extremely sore. I thought I just had a really bad cold so persisted for about 2 weeks before heading to the clinic to get checked out. He said I had a viral sinus infection, so I had to do the sinus rinse and wait it out. Meanwhile I went back to the orthodontist to get him to check me out and he said it must just be a sinus problem. Then I waited again before finally being able to get in to see my regular doctor and the tests all began. Blood tests, xrays of chest and sinuses, negative. Then I decided to do some googling on the internet and found a few places of people with symptoms just like mine. Back to the orthodontist and he made me a new set of retainers and they seem to be fine except the right jaw area around the eye and top of the teeth is extremely sore. When I push on all the top teeth, they don't hurt. This morning as I write this, my right jaw area feels like it is the size of a golf ball yet it doesn't look any different. My tongue is still has a bit of a burning sensation on the right as well. I have another call into the orthodontist and we'll see how he wants to proceed now as I'm at my wits end and don't know where else to go from here.

• JaceyDecember 7, 2014 at 2:11 am

  I started my invisalign treatment in Oct 2009. Almost immediately I developed a bad cough which led to a bad cold. The cold went away but the cough persisted. I visited my doctors about the cough but they couldn't find anything wrong. My dentist noticed the cough and I mentioned to him that it started the time of my first tray but he brushed it off. I continued my treatment for 2.5 years. Five y[Show More]I started my invisalign treatment in Oct 2009. Almost immediately I developed a bad cough which led to a bad cold. The cold went away but the cough persisted. I visited my doctors about the cough but they couldn't find anything wrong. My dentist noticed the cough and I mentioned to him that it started the time of my first tray but he brushed it off. I continued my treatment for 2.5 years. Five years later I still have the cough. I've done several breathing tests, been to ENTs, respirologists and done MRIs/CT scans., cancer, TB tests - they showed nothing wrong with me. I mentioned the invisaligns to the specialists but they won't hear me. A few weeks ago I got a cold - took Buckley's Complete......to my amazement the cough subsided a lot. Last week I decided to put my retainer on and the cough is back. I believe it is the plastic that is causing the cough. The scary part is I don't know how much damage the invisaligns have caused.

• NavinNovember 24, 2014 at 4:28 pm

  I'm a man in my mid 30s and I've this strong man ego to ignore certain bodily discomforts as far as possible and not mention about it. To tell you my story, I've completed my invisalign treatment and I'm now on retainer. They said it might take 1 year but the treatment took me little over 2 years. I couldn't say anything back because they entrapped me by having me sign all those fineprint paperwo[Show More]I'm a man in my mid 30s and I've this strong man ego to ignore certain bodily discomforts as far as possible and not mention about it. To tell you my story, I've completed my invisalign treatment and I'm now on retainer. They said it might take 1 year but the treatment took me little over 2 years. I couldn't say anything back because they entrapped me by having me sign all those fineprint paperworks. You are all right, I've had exact same symptoms. Got severe sore throat, overall discomfort and irritation in mouth everytime I changed new aligner. But it faded within days as I knew I'm coping certain allergic reactions to the plastic. I was asking myself to 'cope it, cope it'. Somehow I wanted to get my teeth back in shape and so I decided stay on it and be suffered. But I didn't know it would cause so many other health problems other than mouth discomfort. I spent thousands of dollars on my gastrointestinal issues I thought was totally unrelated to this allergic reaction. My physicians were clueless what's wrong with me, because tests would come normal. They prescribed me anti-anxiety pills since nothing wrong is found in me, they decided it's my stress causing all that physical problems. I denied taking anti-anxiety pill, as I'm an avid meditator and practice spiritual lifestyle. Now, I've gotten my retainer as the treatment came to it's end last year, ever since my mouth is subtly burning off and on. It's just random, the problem would vary. Sometimes it's my back of the tongue feels like burning, sometimes my lips, and sometimes I would feel if someone is squeezing my neck I mean felt tightness in my throat. They again tried to prescribe me anti-anxiety and some nasal spray. I told them I still have a bottle from my last prescription and denied am not gonna use those anxiety pill but okayed to nasal spray. Didn't do anything. So, it seems like I've been tolerating it for long time than you guys. Some of the symptoms I've had is: -Unexplained lethargy -Appetite swing -depression -panic attacks -overall mouth discomfort on every new aligner change -sore throat, sore mouth Symptoms now I have is: -subtle lip/tongue burning -throat discomfort. -lymph discomfort, ear tube irritation(I guess) -back of my throat and dull ache in the upper back spine area.. Can you guys imagine, I went to ENT to get me scoped three times in less than six months and they saw nothing wrong out there. ? One ND prescribed me strong sets of antibiotics thinking those bad guys in my tummy may be acting up? So many blood tests, stool tests, pressure etc etc.. nothing serious would come up. Yes, at certain point I thought I had cancer and demanded doctors to run those tests while doing all bloodworks, they would look at me strangely and few days later, they would convince me, "you are all right, reports are normal, don't think too much, you are stressed out, may be a change of job.. etc etc" . I'm gonna get back in touch with those orthodontist and describe all this. Probably sue them.

• GraceOctober 2, 2014 at 4:43 pm

  My lips began bleeding, on and off, starting on my first set of Invisalign more than a year ago. It's also accompanied by constant sore throat and dry mouth. I have tried all possible remedies but nothing helps. I toughed it out all this time until my lower lip was infected recently. It was so painful it was impossible for me to function at all. My family physician had to treat me with antibiotics[Show More]My lips began bleeding, on and off, starting on my first set of Invisalign more than a year ago. It's also accompanied by constant sore throat and dry mouth. I have tried all possible remedies but nothing helps. I toughed it out all this time until my lower lip was infected recently. It was so painful it was impossible for me to function at all. My family physician had to treat me with antibiotics. When I talked to my orthodontist later he said Invisalign is FDA approved and it should not be causing these kinds of problems. Now I know better, thanks to all who are sharing your experience. Like couple other people, I'd like to know where/how to get the hypoallergenic trays as my orthodontist didn't seem to know there is such a version. Beverly and Jennifer, do you know if your doctor had to contact Invisalign directly to request for the hypoallergenic trays? I'd do the same if that's the extra step I need to take to ensure I will not be suffering further because of the material used in my Invisalign trays.

• JenniferSeptember 19, 2014 at 4:25 pm

  I started my first set of trays in May of this year, I went through 6 sets of tray. All the while in communication with my dentist that something was wrong. My lips were swollen, chapped, even bleeding. My throat felt like it as closing up and I had trouble swallowing. My dentist was able to provide me with a new set of hypoallergenic trays. I wore tray 6, 7 and 8 of the hypoallergenic trays j[Show More]I started my first set of trays in May of this year, I went through 6 sets of tray. All the while in communication with my dentist that something was wrong. My lips were swollen, chapped, even bleeding. My throat felt like it as closing up and I had trouble swallowing. My dentist was able to provide me with a new set of hypoallergenic trays. I wore tray 6, 7 and 8 of the hypoallergenic trays just fine, my lips were back to normal size and no tingle feeling or swollen throat issues. Now today, I put in tray #9 and bam! Swollen lips, chapped and my throat is closing up! I think the manufacture in Mexico tossed in a regular tray thinking I wouldn't notice!! Well I have and I am not happy!!!!

• LisaJuly 25, 2014 at 3:06 pm

  I am so glad I made this connection and searched this after a sleepless night from a mysterious allergic reaction. I started invisalign 2 days ago. Yesterday, I started getting irritated areas on my tongue and swollen lymphs. But days end...my tongue had swollen and I was getting itchy all over. Calling my ortho 1st thing and getting a refund. Thanks to all for your posts.

• JocelynJuly 8, 2014 at 3:56 pm

  I used Invisalign trays around 2003-2004 and have been using the Vivera retainers since completion during the night. The beginning of June this year, the soft tissues in my mouth (mostly my upper and lower lip) maintained a gradual swelling over the course of almost two weeks. Along with the swelling, I experienced a burning sensation on my tounge as well as on my lips. I saw my allergist, my pcp[Show More]I used Invisalign trays around 2003-2004 and have been using the Vivera retainers since completion during the night. The beginning of June this year, the soft tissues in my mouth (mostly my upper and lower lip) maintained a gradual swelling over the course of almost two weeks. Along with the swelling, I experienced a burning sensation on my tounge as well as on my lips. I saw my allergist, my pcp and a GI. So far, everything has checked out fine. I was suggested to stop use of my trays and was placed on a 5 day treatment of Prednisone, though the swelling was still unexplained. My symptoms resolved after two weeks of the irritation without the use of the trays. After nearly a week without the irritation, my teeth grinding prompted me to use the tray again (unaware at this time the tray had caused the issue). The following day, the tissues in my lower mouth began a tingling sensation and presumed to enlarge again! Though not as bad as the initial reaction, it is so frustrating. It has been two days and nights without the retainer and the swelling and irritation has maintained. I have an appointment with my dentist this Friday and have placed a call to my allergist again. I am almost certain that the trays have caused this reaction now. What if anything can be done about this? SO frustrating.

• GigiJune 12, 2014 at 5:26 pm

  I started invisalign almost 2 years ago. On day two of my first tray I had a sore throat/ear pain/swollen neck lymph nodes. These symptoms re-occurred about 5-6 times in the following months, and my lymph nodes started getting bigger. I'm not an allergic person and never had asthma, so I didn't even think about the connection with the trays. I thought I was getting run down by work/stress, and und[Show More]I started invisalign almost 2 years ago. On day two of my first tray I had a sore throat/ear pain/swollen neck lymph nodes. These symptoms re-occurred about 5-6 times in the following months, and my lymph nodes started getting bigger. I'm not an allergic person and never had asthma, so I didn't even think about the connection with the trays. I thought I was getting run down by work/stress, and under advice of my doc I got tested for HIV/lymphoma/glandular fever etc - all negative. I decided to stop worrying about this until I changed my tray one day and got 4 mouth ulcers and the symptoms again with crazy swollen painful neck and jaw lymph nodes, and that's when I realized that it was the invisalign causing these problems. I spoke to my otho and he brushed it off saying it was impossible as he never heard of it. So I continued the treatment for another 6 months- at which point one of my neck lymph nodes got to the size of a walnut, and excruciatingly painful. I have recently stopped invisalign as I though this was really affecting my health - my teeth feel very uncomfortable without the retainers as they have been moved for over a year and now cannot settle... my lymph nodes are less painful but still big, and I suspect will be so for a few months at least... what a complete and utter nightmare- I wish I had never embarked in this treatment or was advised correctly as soon as I started having these problems!!! Glad I am not alone, though...

• shannonFebruary 27, 2014 at 2:47 am

  I haven't wore my invisalign in a while so I clean them and I put them back in. Then I felt like my breathing went shallow like slow. Then my chest felt like I had an elephant sittimg on my chest. Pretty scary feeling. And the thing is the invisalign never madse me feel like this. And I don't have an allergies.

• RebeccaFebruary 9, 2014 at 12:04 am

  I tried the Invisaligns for about five months. Almost immediately, I started having asthma-type problems, a sore throat, and had swollen lymph nodes in my neck. I always felt like I was walking through a smoky room (I have never smoked in my life.) My doctor ran several tests, and my eosinophils (sp?) were elevated. I stopped using the aligners at that time (almost five months ago), and my eosinop[Show More]I tried the Invisaligns for about five months. Almost immediately, I started having asthma-type problems, a sore throat, and had swollen lymph nodes in my neck. I always felt like I was walking through a smoky room (I have never smoked in my life.) My doctor ran several tests, and my eosinophils (sp?) were elevated. I stopped using the aligners at that time (almost five months ago), and my eosinophils returned to normal. However, my body is still reacting. I still have the "smoky room" feeling in my throat and esophagus, and asthma problems. (I have had exercise-induced asthma in the past, but it always went away when I was in good shape (which I'm in now).) My swollen lymph nodes gradually returned to normal, but it took several months.

• SureshSeptember 12, 2013 at 6:20 am

  Hey Guys, Thanks for all the messages above, now I know my invisalign might be the root cause for my severe allergic reactions. I tried braces first however I had ulcers, then I tired Invisalign, initially it was good and I thanked GOD that I have some fix for my teeth. however I was always getting ulcers in my mouth etc and it was manageable. but since 1 week my cold, sneezing and runny nose i[Show More]Hey Guys, Thanks for all the messages above, now I know my invisalign might be the root cause for my severe allergic reactions. I tried braces first however I had ulcers, then I tired Invisalign, initially it was good and I thanked GOD that I have some fix for my teeth. however I was always getting ulcers in my mouth etc and it was manageable. but since 1 week my cold, sneezing and runny nose is so bad, I am totally exhausted, I was scared that I had asthma. very scared to see bleed in my nose some times. few hours back I removed it. let me see for few days if it can fix the issue. BTW I see that someone said they have hypo allergic ones, if it is there, could you please let me know.

• DianaJuly 10, 2013 at 8:36 pm

  Like some of you, the first symptom I had was a horribly dry mouth I could not relieve. I felt perhaps there was some type of residue on the braces so soaked them in Retainer Brite. The dry mouth continued so I tried soaking in a solution of vinegar and warm water. Nothing seemed to change. Over months the dry mouth became less of a problem but I developed a cough. At first I thought it was e[Show More]Like some of you, the first symptom I had was a horribly dry mouth I could not relieve. I felt perhaps there was some type of residue on the braces so soaked them in Retainer Brite. The dry mouth continued so I tried soaking in a solution of vinegar and warm water. Nothing seemed to change. Over months the dry mouth became less of a problem but I developed a cough. At first I thought it was environmental allergies but the cough continued on to the point that I visited my primary care physician. She gave me all the prescription medications which have cured any cough in the past. The cough continued. We went on a short vacation and one night I forgot to wear the Invisaligns. Magically, within less than 24 hours, my cough was gone. Because I already have two autoimmune diseases, I don't want to risk putting whatever chemicals there are in the Invisaligns in my body any longer. I'm very disappointed my dentist didn't warn me in advance about all the possible side effects.

• DanielleApril 1, 2013 at 8:32 pm

  Karen, I had the same symptoms as you can they couldn't figure out what was wrong with me. They thought I had cancer bc I had swollen lymph nodes all over my body some the size of a golf ball. I had extreme fatigue to the point I couldn't go to work or get out of bed so then they thought it was mono but it wasn't. I spent 2 yrs going to doctors- hematologist, ent, rheumatologist, cat scans,X-r[Show More]Karen, I had the same symptoms as you can they couldn't figure out what was wrong with me. They thought I had cancer bc I had swollen lymph nodes all over my body some the size of a golf ball. I had extreme fatigue to the point I couldn't go to work or get out of bed so then they thought it was mono but it wasn't. I spent 2 yrs going to doctors- hematologist, ent, rheumatologist, cat scans,X-rays and they all showed nothing. I felt no one believed me anymore. On top of it all I then started suffering with extreme gastrointestinal issues. I had refused to go to more specialists bc I just couldn't deal with it. I heard from a friend whose brother is going through the same exact thing as me and she called me to tell me it happened as soon as he began Invisalign. I almost fainted and then realized that my symptoms were at that time as well. I'm so upset that there's no documentation about this so I called my dentist today and he says he's never heard of this at all and he didn't offer me any hypoallergenic options bc he said this reaction was not possible. I showed him all of this info and he doesn't believe me... Very interesting. I'm contacting the FDA and will get to the bottom of this bc no one should ever go thorough what we all did. I spent months on diff. medications, had to be put on steroids bc my throat was closing and thought out all theses treatments nothing worked.

• KarenJuly 3, 2012 at 1:52 pm

  Hi Beverly, i had been using invisalign since Nov 2011. In December i had the most awful cold and flu like symptoms with a hacking cough. I was ill continuously for the next 5 months with excruciating headaches, coughing and a feeling of fluid on my chest. I went to the docs 3 times (i just thought i had a recurring cold). I was prescribed a course of antibiotics which i took reluctantly as i had [Show More]Hi Beverly, i had been using invisalign since Nov 2011. In December i had the most awful cold and flu like symptoms with a hacking cough. I was ill continuously for the next 5 months with excruciating headaches, coughing and a feeling of fluid on my chest. I went to the docs 3 times (i just thought i had a recurring cold). I was prescribed a course of antibiotics which i took reluctantly as i had not taken them for years as i prefer to let my own immunity fight a cold. But i was so rough that i needed something. I know that normally within a day or so, you start to feel better with antibiotics - but as directed I took the whole course. I was no better. I could not exercise and was short of breath performing activities that would normally be a breeze. The final straw came this spring when i attempted a bike ride with my husband. I believe i had what can only be described as an asthma attack. Eventually I took my aligners out for 48hours at one point and realised there was an improvement. I have since returned to the dentist with my issue. He tells me that this has occurred in only 0.1% of circumstances. My health has improved dramatically in the 2 months that i have not worn the aligners. I am now wearing a standard retainer. My dentist now tells me the only option is fixed braces. This is not an option or me as I want invisible ones as per the value proposition sold by Invisalign. He tells me that Invisalign dont do hypoallergenic versions. So, Beverly I am keen to know how you managed to get the hypoallergenic versions. Can you let me know.

• BeverlyMarch 31, 2011 at 5:16 pm

  I'm sorry that you didn't yank those suckers out of your mouth at the first sign of trouble. That's what I did when I began to cough inexplicably. I asked myself, "what is different that could be causing this cough?" The only difference was the Invisalign plates. I immediately discontinued use. I showed my ortho the many complaints about this product, he contacted the company and they replace[Show More]I'm sorry that you didn't yank those suckers out of your mouth at the first sign of trouble. That's what I did when I began to cough inexplicably. I asked myself, "what is different that could be causing this cough?" The only difference was the Invisalign plates. I immediately discontinued use. I showed my ortho the many complaints about this product, he contacted the company and they replaced the trays with their hypoallergenic version which gives me no trouble. I would go to acupuncture or a naturopath or someone who can help strengthen your immune system as soon as possible. Good Luck.

• lindaMarch 5, 2011 at 9:12 pm

  Afer using Invisalign for two years, in December 2010, the first incident, I awoke to severely swollen lips and face. I had chapped lips, cracked and bleeding mouth corners, a burning, tinling sensation of the tongue. This condition continues today with the addition of the inside of my mouth and gums are bleeding and so inflamed and I do not want to brush my teeth or rinse. My skin itches. This [Show More]Afer using Invisalign for two years, in December 2010, the first incident, I awoke to severely swollen lips and face. I had chapped lips, cracked and bleeding mouth corners, a burning, tinling sensation of the tongue. This condition continues today with the addition of the inside of my mouth and gums are bleeding and so inflamed and I do not want to brush my teeth or rinse. My skin itches. This condition has continued with lessening and worsening until today. I went to an allergist and was tested for food allergies. Negative. I have gone to two other doctors. I have restricted my diet, kept food intake logs. I am frustrated and fell horrible. The last doctor has suggested I no longer use the aligners. This is day 3 and the condition seems to be lessening however I have been told by the doctors that it could take a month for all symptoms to disappear. Why was I or my dentist not notified by Invisalign that this condition could occur? How did they get FDA approval? In December 2010 I received my first mailed-directly-to-me replacement aligners from Invisalign via Mexico. Then my nighmare began.