Clinical trial results come as Gilead continues to face lawsuits over side effects of some of its older HIV drugs, claiming the manufacturer delayed introduction of safer formulations to extend it's monopoly over the HIV market.
Appeal comes as Gilead continues to face thousands of HIV drug lawsuits in California state court, alleging that users experienced bone fractures and kidney injuries due to Truvada and other TDF-based medications.
HIV drug settlement does not resolve the Truvada lawsuits, Atripla lawsuits, Stribild lawsits, Viread lawsuits and Complera lawsuits pending in California state court, where tens of thousands of additional claims are filed.
In addition to claims filed in federal court, Gilead faces about 24,000 TDF lawsuits in California state court, each raising similar allegations that the drug maker withheld a safer version of its HIV drugs.
California judges determined Truvada lawsuits, Atripla lawsuits, Stribild lawsits, Viread lawsuits and Complera lawsuits can be pursued by users who developed kidney damage, bone fractures and other side effects from the HIV drugs.
Gilead claims it had no duty to develop safer TAF-based HIV drugs to replace its older TDF-based medications, including Truvada, Viread, Stribild and others, which have been linked to bone fractures, kidney injuries and other side effects.
Properly identifying patients at higher risk of transmission increases the benefits of prescribing certain HIV drugs as prophylactics, researchers determined.
This is the third antitrust trial victory for Gilead involving claims it participated in an Atripla and Truvada pay-to-delay generics scheme
Gilead failed adequately to warn users that its TDF-based HIV drugs could lead to bone demineralization, kidney disease and kidney damage, plaintiffs say.
The Gilead HIV drug lawsuit filed by the Justice Department claimed the drug maker violated patents held by the CDC for the use of Truvada and Descovy as preventative treatments.
