Although side effects of Eliquis may cause severe and uncontrollable bleeding problems, researchers indicate the blood thinner lowers the risk of stroke and systemic embolism compared to aspirin.
The new Xeloda warnings are part of a program reviewing cancer drugs which have been on the market for decades and may need label warning updates.
Researchers found side effects of Xarelto make it a less appealing option than warfarin for patients with heart disease-related atrial fibrillation.
Xarelto and Eliquis bleeding rates were high when the drugs were first introduced without an effective reversal agent.
The findings raise concerns over how healthcare professionals should mitigate the bleeding risks when infections are diagnosed, the researchers warn.
Xarelto, Warfarin and other blood thinners are the leading cause of hospital visits due to drug side effects, leading to calls for closer monitoring
