Bone Fracture Warning Added to Nexium, Prilosec, Other Hearburn Drugs

The FDA is requiring that additional information be provided by several pharmaceutical companies about the risk of bone fractures from Nexium, Prilosec, Prevacid and other heart burn medications

In a drug safety communication released on May 25, the FDA announced that all proton pump inhibitors (PPIs) will now include a warning that they may increase the risk of fracturing bones in the hip, wrist, and spine. The labeling change came after FDA drug safety reviewers looked at a number of epidemiological studies into PPI bone fracture risks.

One such study, published earlier this month in the Archives of Internal Medicine, found that women who took PPIs were 25% more likely to suffer a Prilosec or Nexium bone fracture over an 8-year period than women who did not. The new labeling changes will indicate that the fracture risks appear to be linked to long-term use. FDA officials say that although the studies have looked at people who used the drug for more than a year, the drug facts section of the labels will indicate the possibility of risk after 14 days of continuous use.

Did You Know?

Millions of Philips CPAP Machines Recalled

Philips DreamStation, CPAP and BiPAP machines sold in recent years may pose a risk of cancer, lung damage and other injuries.

Learn More

Drugs that will be affected by the labeling changes include the prescription drugs Nexium, Prilosec, Zegerid, Prevacid, Protonix, Aciphex and Vimovo. The labeling changes will also be applied to over-the-counter drugs including Prilosec OTC, Zegerid OTC, and Prevacid 24HR.

“Epidemiology studies suggest a possible increased risk of bone fractures with the use of proton pump inhibitors for one year or longer, or at high doses,” said Dr. Joyce Korvick, FDA’s Division of Gastroenterology Products deputy director for safety. “Because these products are used by a great number of people, it’s important for the public to be aware of this possible increased risk and, when prescribing proton pump inhibitors, health care professionals should consider whether a lower dose or shorter duration of therapy would adequately treat the patient’s condition.”

The prescription drugs pull in about $14 billion in U.S. sales each year, and many are prescribed for indigestion and heart burn, although with the exception of Prilosec, they are only approved for treatment of ulcers, acid reflux disease and erosive esophagitis. There were about 119 million prescriptions for proton pump inhibitors in the U.S. last year. Some medical experts estimate that as many as 69% of proton pump inhibitor prescriptions were written for “off-label” uses, which have not been approved as safe and effective by the FDA.

102 Comments

  • BillJune 24, 2014 at 9:34 pm

    is there any way we can be compensated for dental work which has to be carried out because of the side affects of Prevacid of which I have been taking for 20 years I am now 61 yrs old and my teeth or splitting and eroding it has been proven that there is in fact a link between prevacid and brittle teeth

  • MaryAnnMay 4, 2014 at 12:59 am

    My Dr. should have taken me off prilosec after my bad bone density test. I don't know what to do and am in fear of falling all the time.

  • BillJune 15, 2013 at 3:18 pm

    I have been taking Nexium for 2 years daily now. Within in the past year I have broken 3 ribs from coughing. A friend of mine told me the other day that Nexium weakens ones bones. I had severe back pain mid back on Monday, went to the doctor Tuesday, had an MRI Thursday for the thoracic spine, and the doctor just called me this morning (Saturday 6/15/13) and told me I have compression fractures at[Show More]I have been taking Nexium for 2 years daily now. Within in the past year I have broken 3 ribs from coughing. A friend of mine told me the other day that Nexium weakens ones bones. I had severe back pain mid back on Monday, went to the doctor Tuesday, had an MRI Thursday for the thoracic spine, and the doctor just called me this morning (Saturday 6/15/13) and told me I have compression fractures at T6, T7, T8 and T9. I think it is time to stop taking Nexium after reading everyone else having the fractures in their bodies.

  • phyllisNovember 2, 2012 at 2:20 am

    2002 on actonel fractured T10 of spine. Switched to fosamax T12 of spine blew apart. Next forteo injection daily for 9 months-caused calicium in my blood to raise- very dangerous. Stopped everything, except prilosec-one every 5 days, which they now say causes fractures. I find that if I eat 1/4 of an apple, that takes care of acid reflux- working on that at the moment. Am 83 yrs old wear a TLSO [Show More]2002 on actonel fractured T10 of spine. Switched to fosamax T12 of spine blew apart. Next forteo injection daily for 9 months-caused calicium in my blood to raise- very dangerous. Stopped everything, except prilosec-one every 5 days, which they now say causes fractures. I find that if I eat 1/4 of an apple, that takes care of acid reflux- working on that at the moment. Am 83 yrs old wear a TLSO brace & have lost approxamately 8 inches since 2002. Went for a bone density test 2 weeks ago & the report said due to degeneraion of my spine they could not do a bone density of my spine????

  • FrankJune 30, 2012 at 12:35 am

    Dealing with the same problems. 53 year old male with Osteoporosis, no family history but over 10 years on Nexium. Canadian class action suit filed but nothing yet. Any other Canadians dealing with this?

  • EmilyFebruary 22, 2012 at 1:00 am

    I am a 53 years old woman using nexium before, now prilosec for over 5 years. For the last three years I've been suffering severe joint pain. Reading the comments, I see I've been lucky I haven't had any fractures. Right now the joint pain is unbearable and I am taking Nsaid for the pain on a daily basis. I don't know what is worst, losing my bones, losing my esophagus, or losing my kidneys. [Show More]I am a 53 years old woman using nexium before, now prilosec for over 5 years. For the last three years I've been suffering severe joint pain. Reading the comments, I see I've been lucky I haven't had any fractures. Right now the joint pain is unbearable and I am taking Nsaid for the pain on a daily basis. I don't know what is worst, losing my bones, losing my esophagus, or losing my kidneys. Something should be done. Please let me know if there is a class action suit.

  • ShawnJanuary 1, 2012 at 9:44 pm

    I have been taking Neium for close to 3 years for GERD and in this time have suffered a fracture of my right ankle and now a fracture of my tibia and fibula both times completely unexplained circumstances. Will be getting bone density test in the coming weeks . Needless to say I will not be taking Nexium anymore.

  • LCAugust 27, 2011 at 4:08 pm

    I have been taking Prevacid or Prilosec (depending on which my insurance covered) for 20 years. Two days without it and the burning in my throat and esophagus makes me miserable. I was recently prescribed weekly mega doses of Vitamin D for 2 months in conjunction with daily vitamin D and multi-vitamins (the daily vitamins are to be continued).Maybe it is time for pharmaceutical companies to come[Show More]I have been taking Prevacid or Prilosec (depending on which my insurance covered) for 20 years. Two days without it and the burning in my throat and esophagus makes me miserable. I was recently prescribed weekly mega doses of Vitamin D for 2 months in conjunction with daily vitamin D and multi-vitamins (the daily vitamins are to be continued).Maybe it is time for pharmaceutical companies to come up with a better alternative. I require several maintenance meds and they all have potential side effects. If I don't take the meds, I feel a lot worse. At this point, I'm willing to take the risk.

  • KarlaAugust 24, 2011 at 5:22 am

    My 38 year old husband began taking several different omeprazole medications including Nexium, Prilosec prescription & OTC, & Zegirid over 10 years ago. In 2008 he suffered a stress fracture in his left foot. A few months later he broke his left wrist from a fall however not the type of fall that should have required a plate & 8 screws to repair as his did. He has severe arthritis in h[Show More]My 38 year old husband began taking several different omeprazole medications including Nexium, Prilosec prescription & OTC, & Zegirid over 10 years ago. In 2008 he suffered a stress fracture in his left foot. A few months later he broke his left wrist from a fall however not the type of fall that should have required a plate & 8 screws to repair as his did. He has severe arthritis in his right wrist however he has never injured it and was told it looks as if he has the hand of a 70 year old. He suffers from cronic back and hip pain and is currently waiting for the opportunity to take off from his place of employment to seek medical care. I hope and pray there isn't damage as some have mentioned above. We were never informed of the possible side effects to his bones. I do strongly believe now that all of his issues revert back to taking these medications.

  • mikeAugust 19, 2011 at 11:13 pm

    STARTED HAVING SEVRE HEART BURN AT AGE 30.... STARTED USING TUMS THEN PEPCID, THE PRILOSED, OMEPRAZOLE, CONTROLS WHATS ITS USED FOR....50 YRS NOW, HAVE AVN...WHAT SHOULD IT THINK.....TELL ME...

  • tinaAugust 15, 2011 at 12:08 pm

    i started taking nexium about 6 years ago i havebeen diagnosed with fibromialga and recently fell and tore mr rotor cup, also haveneck problems and now they want meto take calcium.never hadany problems before

  • RobertAugust 2, 2011 at 11:03 pm

    I've been taking Nexium for 5+ years. Mysteriously fractured a rib that took forever to heal. Doctor had me get a bone density scan. Now, I've just been diagnosed with osteopenia (esp. in hip). I'm a man in his 40's!

  • JudyJuly 21, 2011 at 11:54 pm

    In 2001 I was diagnosed with esophegal cancer Today I am cancer free but still suffer with Gerd and have taken at times 4 nexiums daily. I am in so much pain sometimes I think I am crazy. The 24th of August I will be undergoing a shoulder replacement due to bones crumbling away. I am on 40 mg hydrocodone daily without relief. Glad to know I am not crazy but do greive over my poor quality of life

  • MarkJuly 21, 2011 at 1:08 pm

    I am 47 years old and have acid reflux. I started taking Nexium 8 months ago. I take 40 mgs per day. I recently started getting serious shoulder pain. After I had an x-ray done the Dr. said I had a calcium deposit. Could this be caused by Nexium? I think I am going to stop taking it after reading these horror stories.

  • PatJuly 14, 2011 at 4:35 pm

    Four years ago I started taking nexium and now I can't hardly walk, both of my knee are bone on bone and my ankle and foot on the right leg hurt all the time. I've went thru all the shots and gel shots in both knees and still pain all the time and most days I can't walk. I never had any of this problems until the last few years. Now I take Prilosec,celebrex and cymbalta to help with the pain. Is t[Show More]Four years ago I started taking nexium and now I can't hardly walk, both of my knee are bone on bone and my ankle and foot on the right leg hurt all the time. I've went thru all the shots and gel shots in both knees and still pain all the time and most days I can't walk. I never had any of this problems until the last few years. Now I take Prilosec,celebrex and cymbalta to help with the pain. Is there any help out there?

  • StellaJuly 6, 2011 at 9:11 am

    Not only do I have osteoporosis, spinal stenosis severe scoliosis and spondylosis, causing severe lower back pain, I realized after stopping omeprssole, (Nexium) that my hair is growing back, my dizziness stopped and I believe other problems were caused by this drug. I took Nesium for a few years, then omeprazsole, a total of ten years. I am unable to do any activity withou pain. I also had extrem[Show More]Not only do I have osteoporosis, spinal stenosis severe scoliosis and spondylosis, causing severe lower back pain, I realized after stopping omeprssole, (Nexium) that my hair is growing back, my dizziness stopped and I believe other problems were caused by this drug. I took Nesium for a few years, then omeprazsole, a total of ten years. I am unable to do any activity withou pain. I also had extreme oiliness of my forehead, and other skin issues, not necesssarily resulting from the drugs, but possibly so. I was having recurring UTIs which didn't have usual symptoms, such as itching and burning. Why? According to Harvard Medical School, these meds can interfere with normal bacteria, as well as absorption of calcium. I was in very good physical condition until about 3 years ago, but have gradually deteriorated to serious problems. I still only take a blood pressure medicine (pain causes higher blood pressure). Acid reducers such as Tums etc. are helpful with acid. From age 75 to 85 I have apparently destroyed my good health.

  • LoriJune 14, 2011 at 4:09 pm

    I have been on gerd medications for years. Prilosec, Prevacid and Nexium. Over the years, I have suffered facial and jaw pain. Two yrs ago I was walking my puppy when she seen a cat and tried to pull me. I grabbed a tree and my wrist snapped and broke in two places. To this day it still hurts and henders my daily activities. I have also experienced a lot of shoulder pain over the years. A[Show More]I have been on gerd medications for years. Prilosec, Prevacid and Nexium. Over the years, I have suffered facial and jaw pain. Two yrs ago I was walking my puppy when she seen a cat and tried to pull me. I grabbed a tree and my wrist snapped and broke in two places. To this day it still hurts and henders my daily activities. I have also experienced a lot of shoulder pain over the years. All of which has been documented by doctors. I just heard about these medications causing these problems. I'm interested in getting more details on this issue.

  • DebraJune 13, 2011 at 7:43 pm

    I have been on Nexium for almost 10 years or more. They gave it to me for portal hypertention. They didnt want me to get any ulsers. Never had one , nor did i have heartburn. They last 5 years has been constant pain they said I had severe arithitis and was nothing tey could do. I needed a new hip and my left ancle stayed twice its size. I'm now in a wheelchair because it is to painful to walk. The[Show More]I have been on Nexium for almost 10 years or more. They gave it to me for portal hypertention. They didnt want me to get any ulsers. Never had one , nor did i have heartburn. They last 5 years has been constant pain they said I had severe arithitis and was nothing tey could do. I needed a new hip and my left ancle stayed twice its size. I'm now in a wheelchair because it is to painful to walk. The pain was so bad I would lose my balence and fall. My faamily don't understand they tell if I just walk more it will get better. I feel like i'm fighting a losing battle. At 53 years I can't do the things I use to. I am confined to the house and somehow it don't seem fair.

  • lisaJune 6, 2011 at 4:47 am

    I STARTED OF TAKING NEXIUM FOR THE ACID REFLUX ,PROBLEMS WAS STILL HAPPENING SO THE DR CHANGE ME TO PROTONIX MY STOMACH WAS STILL BURNING ,ACID WAS STILL CAUSING ME TO HAVE TO SET UP IN THE BED TO SLEEP . STOMACH BURNING EVEN WHEN I HAD NOT ATE ANYTHING. THEN WHEN I DO EAT OR DRINK SOMETHING I GOT HEART BURN BAD . FINALLY GOT CHANGED TO ACIPHEX 20MG WHAT AM STILL ON NOW AND SOME TIMES IT DONT WO[Show More]I STARTED OF TAKING NEXIUM FOR THE ACID REFLUX ,PROBLEMS WAS STILL HAPPENING SO THE DR CHANGE ME TO PROTONIX MY STOMACH WAS STILL BURNING ,ACID WAS STILL CAUSING ME TO HAVE TO SET UP IN THE BED TO SLEEP . STOMACH BURNING EVEN WHEN I HAD NOT ATE ANYTHING. THEN WHEN I DO EAT OR DRINK SOMETHING I GOT HEART BURN BAD . FINALLY GOT CHANGED TO ACIPHEX 20MG WHAT AM STILL ON NOW AND SOME TIMES IT DONT WORK . HAVING TROUBLE WITH MY BONES ACHING AND CRACKING THEN EVEN TELLING ME SOMETHING ABOUT MY DISC IN THE BACK . CAN'T WORK FOR THE BODY ACHES .

  • TerryMay 26, 2011 at 2:12 pm

    Get off acid reflux meds. Try eating organic foods. Google acid relux or Gerd, and you'll see that the major culprit is pesticides. My husband had a problem with orange juice. When we switched to organic oj, no more problems. I've "cured" my hi-pylori stomach problems with Manuka honey from New Zealand. One or two tablespoons a few times a day soothes the throat and stomach. Another interesting t[Show More]Get off acid reflux meds. Try eating organic foods. Google acid relux or Gerd, and you'll see that the major culprit is pesticides. My husband had a problem with orange juice. When we switched to organic oj, no more problems. I've "cured" my hi-pylori stomach problems with Manuka honey from New Zealand. One or two tablespoons a few times a day soothes the throat and stomach. Another interesting thought is, why would someone want to eliminate stomach and digestive acids when they're so important for proper digestive functioning. This has to cause more health problems down the line. Before 1970, acid reflux was an occaisional problem. Then the chemicals were added to our foods along with the side effects. In 2001, I was poisoned by Levaquin and Cipro. I have a torn tendon in my hip. So far I cannot find a lawyer to take the case since tooooo much time has gone by and they can't pinpoint exactly when the tear occurred. They've known about the tendon problems since the mid 1990's. If we get back to organics and basics, and off all the medications, a lot of problems would be eliminated.

  • MARYMay 25, 2011 at 6:34 pm

    TO WHOM THIS MAY CONCERN, SINCE I HAVE BEEN TAKEN NEXIUM I HAVE HAD NOTHING BUT ACHES AND PAIN. THE PAIN IS UP AND DOWN MY SPAIN. IT HURTS SO BAD THEY PUT ME ON TYLENOL W/CODEINE ALSO IBUPROFEN 800mg. I CHANGE DR. AND TOLD HER SINCE I GOT HEART BURNS EVEN WITHOUT EATING ANYTHING MY OLD DR. PUT ME ON NEXIUM AND STILL THE HEART BURNS ARE HERE AND PAIN I NEVER FELT BEFORE. I TOLD HER I REALLY THINK [Show More]TO WHOM THIS MAY CONCERN, SINCE I HAVE BEEN TAKEN NEXIUM I HAVE HAD NOTHING BUT ACHES AND PAIN. THE PAIN IS UP AND DOWN MY SPAIN. IT HURTS SO BAD THEY PUT ME ON TYLENOL W/CODEINE ALSO IBUPROFEN 800mg. I CHANGE DR. AND TOLD HER SINCE I GOT HEART BURNS EVEN WITHOUT EATING ANYTHING MY OLD DR. PUT ME ON NEXIUM AND STILL THE HEART BURNS ARE HERE AND PAIN I NEVER FELT BEFORE. I TOLD HER I REALLY THINK IT'S FROM THESE PILLS.

  • CharMay 16, 2011 at 8:02 pm

    I have been on Nexium for about 1 1/2 yrs, due to ulcer and previous and continous hi-pylori, i lost strength in my legs back arms, weakness where i couldnt even push a cart, in walmart. or walk a very short distance, back problems, and a sik had to be removed in my neck and a cadaver bone put in. i quit Nexium and i am regaining some of my strength back, however an hour ago i fell just getting up[Show More]I have been on Nexium for about 1 1/2 yrs, due to ulcer and previous and continous hi-pylori, i lost strength in my legs back arms, weakness where i couldnt even push a cart, in walmart. or walk a very short distance, back problems, and a sik had to be removed in my neck and a cadaver bone put in. i quit Nexium and i am regaining some of my strength back, however an hour ago i fell just getting up for a chair, I need answers, i am in pain and i don\'t want to live on pain pills.

  • GailMay 12, 2011 at 9:44 pm

    I am 58 years old and I started taking nexium in 2007 for acid refex. Now my teeth are disintegrating at the gum line. I take 40 mg a day, sometimes twice a day. Did Nexium cause this. I am looking at losing all my teeth. This started about two years ago. When my teeth first started losen up, I had a feeling it could have been cause by the Nexium. What can a person do about it. I work part time [Show More]I am 58 years old and I started taking nexium in 2007 for acid refex. Now my teeth are disintegrating at the gum line. I take 40 mg a day, sometimes twice a day. Did Nexium cause this. I am looking at losing all my teeth. This started about two years ago. When my teeth first started losen up, I had a feeling it could have been cause by the Nexium. What can a person do about it. I work part time at min wage with no medical or dental coverge. I don't know how I can afford the dental work.

  • millieMay 5, 2011 at 1:25 pm

    i have been taking nexium and have had 4 breaks in all this time. what gives. i also take things for my bones and once a month bonivia and hopefully that will stop the breaks.

  • AnnApril 15, 2011 at 8:04 pm

    I have taken a proton pump inhibitor for about 10 years. At the beginning I was started off with Protonix, Prevacid and Prilosec. In each case I had side effects including very intense bone pain as we shuffled through the various drugs. I could not and still can't go a day without some kind of help with very bad GERD. The resulting solution for me became Aciphex. No problems at all, no bone b[Show More]I have taken a proton pump inhibitor for about 10 years. At the beginning I was started off with Protonix, Prevacid and Prilosec. In each case I had side effects including very intense bone pain as we shuffled through the various drugs. I could not and still can't go a day without some kind of help with very bad GERD. The resulting solution for me became Aciphex. No problems at all, no bone breaks in all these years and had a bone density test last year and am still within normal tolerances for my age. Not sure if I just hit on a good alternative or just have good genes but this medication has been a God send to me. The only problem I now have is my insurance company has just notified me that they refuse to fill it anymore. I had been paying much more for it on a co-pay than other drugs but now they won't dispense it at all. There is no generic until 2013 in the USA and it's very expensive. So my plan is to get it from a Canadian pharmacy at considerably less cost for the name brand and they also have a generic. Shows you how intolerable our medical system has become with this kind of financial ripoff. I'm posting this in case any of you need still medication but haven't tried Aciphex. Bone pain is a serious and known side effect of proton pump inhibitors so I don't understand if you reported it to your doctors why they left you on the drug(s). The bone pain started for me almost immediately and relented when I went off of the above noted prescribed meds but it was horrible enough that I refused to continue taking ithem and moved on to others until I found one that worked for me. Good luck to all of you, especially those that have bone damage.

  • RhondaApril 7, 2011 at 12:51 pm

    I've been taking Nexium for 4-5 years and within the past year I've broken my pelvis in three places and most recentlt my wrist in two places. I'm 51 but athletic and in good shape overall. I thoght how odd that I would have these kinds of fractures in a one year period. Now I'm really wondering if this is the real problem!

  • tjcole76April 5, 2011 at 6:41 pm

    I have been on Nexium, 40mg twince a day, for at least 9 years now and other meds before that. In just the last few years I have broke my toes, arms, wrist and last fall my femor broke in many places just from falling from standing up, this includes breaking the femor completely accross. I may never walk again without sometype of aid. and I am still using a walker and cane after 5 months and in qu[Show More]I have been on Nexium, 40mg twince a day, for at least 9 years now and other meds before that. In just the last few years I have broke my toes, arms, wrist and last fall my femor broke in many places just from falling from standing up, this includes breaking the femor completely accross. I may never walk again without sometype of aid. and I am still using a walker and cane after 5 months and in quite a bit of pain too. I have lots of screws and a large plate to match my scar that runs from my lower knee up to my thigh. They ran a bone desity test and its was normal and only lost 7% in 4 years. This scares me but may explain all the bones I have broke latley and I am only 52. Yet I do not know what I will do without Nexium, this medication makes it so my chest and stomach make it through each day, its a great medication. Can we take something to help prevent further broken bones?

  • SharonApril 1, 2011 at 1:31 am

    I was taking Prilosec for about 15 years and then was put on Nexium. I noticed that my ribs was hurting so I went to the doctor and found out that I had fractured my ribs. I never did fall or get hit at my ribs. What is being done about these medications that is causing us all to have these fractures. Who can I go to, to file lawsuit.

  • maryMarch 31, 2011 at 1:18 pm

    I have been having pain in my bones i said to my dr. i have been having a lot pain in bones like went siting in my chair i will have my bones snap all the time i hurt so bad that i'm up all night in pain. i tride talking to my dr. i get no were.i need to no want to do?

  • taylorMarch 25, 2011 at 11:19 pm

    my wife was started on prilosec several years ago due to GERD, I am a RN myself and last year my wife sustained a pubic ramus fracture that over a year later is still hurting her to a point that she requires motrin and tramadol for pain control in order for her to work. I have a long history in the medical field and now I find out about this side effect, which it may or may not contributed to he[Show More]my wife was started on prilosec several years ago due to GERD, I am a RN myself and last year my wife sustained a pubic ramus fracture that over a year later is still hurting her to a point that she requires motrin and tramadol for pain control in order for her to work. I have a long history in the medical field and now I find out about this side effect, which it may or may not contributed to her fracture and chronic pain. If it did and they knew about this risk then they are liable and I am interested in discussing her situation in more detail.

  • ToemettraeMarch 18, 2011 at 2:26 am

    My Mother has been on these types of medications for over 10 years and has been in severe pain in her bones. She has suffered from two or more bad disc and deteriation in her back. She has extensive pain in her hands, legs, back, and arms. Some days she can't even move and she is only 49 years old. What can we do to help these people, like my mother, that has been suffering due to taking these dru[Show More]My Mother has been on these types of medications for over 10 years and has been in severe pain in her bones. She has suffered from two or more bad disc and deteriation in her back. She has extensive pain in her hands, legs, back, and arms. Some days she can't even move and she is only 49 years old. What can we do to help these people, like my mother, that has been suffering due to taking these drugs over the years. That is only hurting them instead of helping them.

  • JoannaMarch 10, 2011 at 4:12 pm

    My 4 year old daughter was born with her small intestine and duodeum (sp) not connected. This was not discovered until she was 7 months old. In the mean time she was given liquid prevacid to take 3 times a day by mouth.. She was on this for 7-8 months until they found what was wrong. About 2 years ago she started to have her wrist pop and her elbow coming out of her socket. The Dr. have said this[Show More]My 4 year old daughter was born with her small intestine and duodeum (sp) not connected. This was not discovered until she was 7 months old. In the mean time she was given liquid prevacid to take 3 times a day by mouth.. She was on this for 7-8 months until they found what was wrong. About 2 years ago she started to have her wrist pop and her elbow coming out of her socket. The Dr. have said this is nurse's elbow but no way it happens on its own. The dentist is saying that her tooth density is bad she has already had to have 2 teeth pulled. Just curious if this is why?

  • TraciMarch 8, 2011 at 7:34 pm

    I suffered w/ heartburn to point of almost everything including water gave me heartburn. When I started on first Nexium, then Prilosec, it was like a God send. I think people gain wt with this medication because they can eat again. I am 53 and starting to have S/S of arthritis and have back pain. No fractures. I take vit D, calcium and I exercise. I would do almost anything besides quit taking Pri[Show More]I suffered w/ heartburn to point of almost everything including water gave me heartburn. When I started on first Nexium, then Prilosec, it was like a God send. I think people gain wt with this medication because they can eat again. I am 53 and starting to have S/S of arthritis and have back pain. No fractures. I take vit D, calcium and I exercise. I would do almost anything besides quit taking Prilosec. I feel it saved my life.

  • GaryMarch 7, 2011 at 8:31 pm

    In 15 years I have progressed from taking Zantac to taking Prilosec, then Nexium in the past 10. I am now sitting here with 3 broken toes and a fractured elbow with bills mounting to 15,000 dollars. I can't work, can't pay my doctors, and waiting for the next side effect of Nexium to hit me. I have compressed disks in my neck and have lost 2 1/2 inches in height and suffer neck and back pain co[Show More]In 15 years I have progressed from taking Zantac to taking Prilosec, then Nexium in the past 10. I am now sitting here with 3 broken toes and a fractured elbow with bills mounting to 15,000 dollars. I can't work, can't pay my doctors, and waiting for the next side effect of Nexium to hit me. I have compressed disks in my neck and have lost 2 1/2 inches in height and suffer neck and back pain continuously. The next step may be surgery on my neck to stabilize my vertebrae. How long has Nexium known about this? My right knee collapes frequently and caused the fall that shattered my elbow. I am 58 and have the structure of an 80 year old.. What now?

  • jeffMarch 6, 2011 at 5:26 am

    i'm a 46 year old male.6 years ago i was told that i had several spine fractures and also ribs..back in 2002 i started taking previcaid for three years and then some over the counter drugs .then they put me on nexium. i have been on disability for five years i live in severe pain lot of pain meds and also i had to have a spinal cord stimulator put in my back.i have three bad disk in my lower back[Show More]i'm a 46 year old male.6 years ago i was told that i had several spine fractures and also ribs..back in 2002 i started taking previcaid for three years and then some over the counter drugs .then they put me on nexium. i have been on disability for five years i live in severe pain lot of pain meds and also i had to have a spinal cord stimulator put in my back.i have three bad disk in my lower back but my bone density is a -3.7 so i can't have surgery my whole body hurts. i just seen a advertisement for these drugs today and now know what is going on. my doctors couldn'tfind out what was wrong .i will see them asap.i'm sorry to hear how this drug has hurt so many people.

  • DeidreFebruary 18, 2011 at 10:37 pm

    I started taking Prilosec at age 30. When I became pregnant at age 33, I discussed with one of my OB's, which med should I switch to, as the acid reflux was almost unbearable when I was not pregnant. Just newly pregnant, I was told by one of the doctors NOT to take the Prilosec, as no tests are ever done on pregnant women. Five months later, after trying "safer" meds and eating Tums by the hand[Show More]I started taking Prilosec at age 30. When I became pregnant at age 33, I discussed with one of my OB's, which med should I switch to, as the acid reflux was almost unbearable when I was not pregnant. Just newly pregnant, I was told by one of the doctors NOT to take the Prilosec, as no tests are ever done on pregnant women. Five months later, after trying "safer" meds and eating Tums by the handful and still having the reflux, I was told by a different doctor in the same clinic, that we had to weigh the risks and that I was far enough along that the Prilosec should not effect the baby. Our daughter was born via c-section and the following weeks were hell. I continued to take the Prilosec, as no one told me not to and attempted to breast feed. Our daughter pretty much screamed the first 9 weeks of her life. Repeatedly told she had reflux/colic, we did everything the baby books said. When we finally insisted there was something more wrong, x-rays were done, and revealed multiple fractures. We were then investigated for child abuse and our daughter was tested for Osteogenesis Imperfecta(brittle bone disease.) We were cleared of the abuse charges, almost instantly. But almost 2 1/2 years later, we are still searching for answers on why she broke, as the OI tests came back negative. I stopped breast feeding at 6 weeks after I lost my milk and our daughter never broke past 9 weeks old. The doctors in the clinic we went to, all stand behind that Prilosec couldn't have caused these problems. But if it can leach calicium out of my bones, it is a known fact, that the baby gets everything first. If a class action suit is filed, I want to know about it. Our daughter is now 2 1/2 yrs old and has never born after 9 weeks. I now will eat the handfuls of Tums and only when I am desperate, will I take the Prilosec.

  • brendaFebruary 13, 2011 at 3:57 pm

    also, i forgot. to the people having gum or teeth problems; try taking at least 800 mg of folic acid daily. after a while you will notice a tremendous difference

  • SeanFebruary 8, 2011 at 4:42 pm

    Omg my shoulder my arm to fingers my ass my feet chest my head panic attacks,Gettin surgery on carp,tunnel and elbow,should I just stop takin this pill the dr said I have to take it or get cancer in my esophagus ??????????? F this pill I'm done and I'm getting a lawyer

  • HerbFebruary 7, 2011 at 2:54 pm

    I see lots of questions. Does anyone have any answers?

  • KerryJanuary 9, 2011 at 3:34 am

    I am 35yrs and have been taking Nexium for about 4yrs now. I have had a scope and it was determined I had a small hiatal hernia and the gastroenterologist said Nexium 1-2x's per day, no surgery necessary. Without the medication, I ended up with a severe throat infection with every simple cold because my esophagus was raw from acid reflux. Now today I noticed 4 of my front teeth are severly crac[Show More]I am 35yrs and have been taking Nexium for about 4yrs now. I have had a scope and it was determined I had a small hiatal hernia and the gastroenterologist said Nexium 1-2x's per day, no surgery necessary. Without the medication, I ended up with a severe throat infection with every simple cold because my esophagus was raw from acid reflux. Now today I noticed 4 of my front teeth are severly cracked and others just starting. After reading all these posts, it seems I should stop the medication imediately...but then suffer again from the acid reflux. I fear what this has done to my teeth...and the rest of my body. Not to mention the horrible migraines I've increasingly gotten over the last few years...another side effect?? I will find out soon what these doctors now have to say or recommend. Unfortunate!

  • debbieDecember 29, 2010 at 12:03 pm

    I've been on prilosec for 2 years and also have Barrettes I also heard that it can cause pneumonia has any one else heard this? The reason I ask is I went to the doctor yesterday for chest congestion which my doctor said would have turned into pneumonia if I hadn't come in. This happened back in October also. I would like to get off this but if I don't take it my acid reflex is unbearable.

  • JoyDecember 12, 2010 at 12:57 pm

    i have been on nexium 40 mg for a very long time,was told to keep taking it from my gastroenterology doctor this was just about a month ago after having a colonoscopy and a endoscopy done,went to doctor because of severe pain in my joints,ankle ,feet,knees, i was sent to arthritus dr he then diagnoised me with rumitoid arthritis,since then my hips and back have started hurting the same way,the pa[Show More]i have been on nexium 40 mg for a very long time,was told to keep taking it from my gastroenterology doctor this was just about a month ago after having a colonoscopy and a endoscopy done,went to doctor because of severe pain in my joints,ankle ,feet,knees, i was sent to arthritus dr he then diagnoised me with rumitoid arthritis,since then my hips and back have started hurting the same way,the pain is to the point that i can not sleep at night without extreme pain meds, went to a podietrist for the feet and ankles due to not being able to stop the pain, didn't know about the warning of nexium till a friend told my husband just yesterday,now i am wondering if some of this is caused by the long use of nexium.

  • MarilynDecember 9, 2010 at 8:05 pm

    Early this year, I had a very severe tibia plateau fracture (in two places) and the fibula broke as well. I had stepped onto a high, bouncy surface and it threw me into the air, and my leg made a Crack, pop, pop sound as it broke in 3 places. I had been taking Prilosec and Prevacid over the previous 3 to 4 years. I take lots of calcium, have been a huge user of dairy products over the years, bu[Show More]Early this year, I had a very severe tibia plateau fracture (in two places) and the fibula broke as well. I had stepped onto a high, bouncy surface and it threw me into the air, and my leg made a Crack, pop, pop sound as it broke in 3 places. I had been taking Prilosec and Prevacid over the previous 3 to 4 years. I take lots of calcium, have been a huge user of dairy products over the years, but still had this severe break. Another culprit is carbonated beverages. If you drink a lot of carbonated beverages you also increase your chances of severe bone breaks. Unfortunately, since Prilosec and Prevacid are OTCs I'd think it would be difficult to prove usage of the products. My physician just gave me a prescrip from Nexium but I have told him I won't be filling it. Tums and Maalox are relatively safer and effective.

  • LeslieDecember 4, 2010 at 1:33 am

    I have taken prilosec or nexium for Acid Reflux for at least ten years. I have had 4 back surgeries and i knee replacement and i fell and broke my hip in 2009. I cannot stop taking these drugs. I have and Tums or Milk of Magnesium do not help. Right now Nexium is the way I get any relief. If someone had told me the drugs could weaken my bones I would have tried jarder to find relief !

  • LindaNovember 23, 2010 at 10:38 am

    I have taken Prilosec OTC for over four years now. (I think I took Prevacid for a month in the middle of that time period.) I have tried to stop a couple of times and the acid reflux/pain is unbearable. I have had bone loss in my teeth, and have had a compression fracture of L-1 and a broken wrist from stepping off a 18 inch stone wall 4 months ago. I am a 47-year old woman who walks 5-6 miles[Show More]I have taken Prilosec OTC for over four years now. (I think I took Prevacid for a month in the middle of that time period.) I have tried to stop a couple of times and the acid reflux/pain is unbearable. I have had bone loss in my teeth, and have had a compression fracture of L-1 and a broken wrist from stepping off a 18 inch stone wall 4 months ago. I am a 47-year old woman who walks 5-6 miles per day and have always been in excellent health.

  • cyndiNovember 18, 2010 at 11:04 am

    Regarding Maggie's comment about her teeth...mine are also disintegrating at the gum line and above. I first noticed it about a year ago on one tooth, and now I can see little beginnings on the majority of my teeth. The initial one I noticed has gotten much worse. I have been on PPIs for probably close to ten years. I have always had strong bones and no dental problems. Last Feb I barely rolle[Show More]Regarding Maggie's comment about her teeth...mine are also disintegrating at the gum line and above. I first noticed it about a year ago on one tooth, and now I can see little beginnings on the majority of my teeth. The initial one I noticed has gotten much worse. I have been on PPIs for probably close to ten years. I have always had strong bones and no dental problems. Last Feb I barely rolled my ankle and ended up with a fracture. I have severe reflux 24/7, but I will stop taking it immediately.

  • PamNovember 15, 2010 at 5:25 pm

    I have been taking Prilosec for ony 4 years (works awesome) but during this time period, I have broke my arm and knee in falls. I work out, brisk walk and also lift weights, I should not have weak bones. We do need a lawyer. I'm tired of heartburn, if we can put a man on the moon, we sure certainly be able to cure heartburn without added risks!

  • TomNovember 8, 2010 at 4:59 pm

    Well, it finally makes sense! I've been having symptoms of osteoporosis for a few years now. About 10 years ago, I began having symptoms of acid reflux and was put on a sample prescription PPI. Not being able to afford the prescription, I started trying out various over the counter relievers. I ultimately decided on Prilosec and have been taking Prilosec OTC daily for about 9 years. I'm 42 ye[Show More]Well, it finally makes sense! I've been having symptoms of osteoporosis for a few years now. About 10 years ago, I began having symptoms of acid reflux and was put on a sample prescription PPI. Not being able to afford the prescription, I started trying out various over the counter relievers. I ultimately decided on Prilosec and have been taking Prilosec OTC daily for about 9 years. I'm 42 years old, but joke around that I feel 72. My pains began a couple of years after taking Prilosec in the joints of my fingers. I would occasionally bump them into something and the pain was tremendous - feeling like I had broken the bone. I was advised to take some Glucosamine supplements, which I have daily for about 7 years. Six years ago I had bent over to pick up my 2 year old and was treated with sciatica. Over the years, the sciatica returns off and on quite often, with variation levels of pain. I thought my quality of life went down then...it was just the beginning. Since then, I can "throw" out the back with just plugging in a lamp, coughing, sneezing, or just driving somewhere for more than 45 minutes. I have increased headaches to the point of having a brain scan performed to see what the issue was. I have been tested for diabetes, have had various blood tests, have have had MRIs performed, and numbers of x-rays, but never a bone mass scan. I went on a walk for diabetes about 2 years ago and was given a neroma in my left foot, where it feels like I'm walking on a rock all day, every day. I see a podiatrist every three months to have a shot to temporarily alleviate the pain. I have had tennis elbow and "reverse" tennis elbow in both elbows, and currently have dealt with the pain in both elbows for about 4 months now. About a year ago I fractured a rib by leaning over the center console in my truck. I have had my knee just "go out" on me at times, leaving me in pain for weeks. I don't sleep well due to the pain. I don't enjoy life like I used to. At times, I just want to sit and cry, but it won't do any good. When I miss a dose of Prilosec, the acid reflux comes back with a vengeance. Currently, I have pain in my shoulders, lower back, fingers, elbows, head and stomach. My memory has gotten pretty bad that it's starting to worry me, too. I thought it was just due to me dealing with pain every day, but after what I have read, perhaps it's the Prilosec. It's also hard to tell what kind of bowel day I'm going to have, as those 'habits' have changed, too. My stomach gets upset at the smallest thing, and will be really loose and watery, while other times I feel so compacted and full that it tears/rips when leaving the body...sorry so graphic, but it is what it is. I honestly don't know what I want to do, cause there is tremendous pain either way, here....should I stop the Prilosec and try to deal with that pain, or should I continue with the pill and try to supplement my body with minerals and vitamins. I already take vitamins and extra calcium every day, along with glucosamine.

  • liliOctober 12, 2010 at 9:56 pm

    I have been taking nexium for a year i have been hearting so much my back killing me my hip it came to the point where i could not walk sometimes i was crying i did not know what was going on we run out of insurance and i could not aford to go get it after only couple of days without nexium my back start feeling beter my hip its not hearting so bad anymore it really help me for gerd but i will ne[Show More]I have been taking nexium for a year i have been hearting so much my back killing me my hip it came to the point where i could not walk sometimes i was crying i did not know what was going on we run out of insurance and i could not aford to go get it after only couple of days without nexium my back start feeling beter my hip its not hearting so bad anymore it really help me for gerd but i will never take it again but i feel my bones cracking when i get up from bed or doing anything around the house and im only 28 what is next.

  • TinaSeptember 29, 2010 at 12:33 am

    I have Been on Nexium Prilosec Prevacid and Protonox for over 15 yrs Nexium and Prilosec the longest I have never put 2 and 2 together but I have had many Broken toes My wrist and hip give me problems I have had my wrist xrayed several times I work for a Dr My Knees back wrists and hips hurt all the time Im 45 yrs old not long ago I had a Bone Density Test and was told I h[Show More]I have Been on Nexium Prilosec Prevacid and Protonox for over 15 yrs Nexium and Prilosec the longest I have never put 2 and 2 together but I have had many Broken toes My wrist and hip give me problems I have had my wrist xrayed several times I work for a Dr My Knees back wrists and hips hurt all the time Im 45 yrs old not long ago I had a Bone Density Test and was told I have osteopenia the onset of osteoperosis and was told to take calcium suppliments I need something for my stomach which I have GERD so Im gonna see if Zantac 150 will do it gonna try it for a couple days all the stuff Im hearing is scaring me and truthfully I dont want this getting any worse I hope we can get a laywer to listen to us there is no way I want to get older any faster than I have to and the way my body is feeling I dont like it all as I am writing this I am thinking of all the things how many times I could not walk and heard my ankle crack when I twisted it I hope some one will help all of us with this problem I am really pissed no Doctor ever told me about any of this

  • LisaSeptember 23, 2010 at 3:16 am

    So, I guess I am doomed. My "silent reflux" causes sinus infections and asthma. I get sick if I don't take medicine for acid reflux. Even if I had surgery to correct the condition, the doctor said I'd have to take this medication. My wrist has broken. I bent over to pick something up, and a rib broke. No one would blame the Prilosec because I am an old lady now. They told me to take Fosama[Show More]So, I guess I am doomed. My "silent reflux" causes sinus infections and asthma. I get sick if I don't take medicine for acid reflux. Even if I had surgery to correct the condition, the doctor said I'd have to take this medication. My wrist has broken. I bent over to pick something up, and a rib broke. No one would blame the Prilosec because I am an old lady now. They told me to take Fosamax...I'd never take that. I wonder if all my calcium and Vitamin D can hold this off.

  • JudySeptember 10, 2010 at 7:05 am

    I am A RN and have missed several months of work over the past 10 yrs. 6 yrs ago i experience a fracture of my right tibia, and this spring a fracture of my right wrist . I also have degenerative disk. What bone is next????

  • EllisAugust 21, 2010 at 7:00 pm

    I have been taking first Prilosec and then Nexium for over 15 years. In Dece 2006 I got out of bed and my right leg colapsed fracturing my hip. I had surgery which inserted three screws in my hip. For the next four months my hip did not mend and it was recommended that I have total hip replacement surgery. During pre op testing it was determined that I needed four way coronary bypass surgery ([Show More]I have been taking first Prilosec and then Nexium for over 15 years. In Dece 2006 I got out of bed and my right leg colapsed fracturing my hip. I had surgery which inserted three screws in my hip. For the next four months my hip did not mend and it was recommended that I have total hip replacement surgery. During pre op testing it was determined that I needed four way coronary bypass surgery (CABG). I had that surgery in May 2007. In August 2007 I had total hip replacement surgery. In July 2008 I had back surgery to fuse L5 and SI vertabrae. In August 2009 it was determined that I needed total hip replacement surgery on my left hip. this was performed in August 2009.

  • JudyAugust 20, 2010 at 2:38 am

    I have been on Nexium for about 2 yrs. I recently had a bone density scan which showed severe bone loss not only in several vertebrae but also in the pelvic region. Have worked in the medical field for many years yet my doctor never discussed any possibility of this risk. I am still relatively young (51) and was told I have the bones of an 80 yr. old woman. As a nurse I am very concerned of the ty[Show More]I have been on Nexium for about 2 yrs. I recently had a bone density scan which showed severe bone loss not only in several vertebrae but also in the pelvic region. Have worked in the medical field for many years yet my doctor never discussed any possibility of this risk. I am still relatively young (51) and was told I have the bones of an 80 yr. old woman. As a nurse I am very concerned of the type of tx. available , if any. Who will bear the financial responsibility for my care? Certainly not the pharmecutical co. who is making a fortune off my misfortune.

  • Worried MomAugust 19, 2010 at 1:12 am

    My 9 year old son who has ALWAYS been very active and played baseball and football since he was 5 was prescribed Nexium 40mg every morning and Zantac 150mg every night. Right at his 6 month of taking them, he was running, typical and fell and broke his left wrist, both bones and received a frontal lobe concussion. Eight weeks later after getting cast off and the ok to play, he pitched an inning a[Show More]My 9 year old son who has ALWAYS been very active and played baseball and football since he was 5 was prescribed Nexium 40mg every morning and Zantac 150mg every night. Right at his 6 month of taking them, he was running, typical and fell and broke his left wrist, both bones and received a frontal lobe concussion. Eight weeks later after getting cast off and the ok to play, he pitched an inning at a ballgame and did fine, the next inning he threw the ball and his right elbow popped. Fractured it. In May my husband seen something on t.v. about Nexium fractures and he stopped him from taking the meds. We are terrified now and he is fishing until we can make sure his bones are ok.

  • DeeAugust 17, 2010 at 5:02 pm

    I was diagnosed approximately ten years ago. Nexium was the only thing that has really worked the best, but unfortunately I can't afford $l75 price tag. I have been alternating between Zegerid, Prilosec, Prevacid and any generic depending on the price. I did have to have hip replacement surgery in 07 which left me with foot drop. I also have simliar leg issues going on the left side. My back a[Show More]I was diagnosed approximately ten years ago. Nexium was the only thing that has really worked the best, but unfortunately I can't afford $l75 price tag. I have been alternating between Zegerid, Prilosec, Prevacid and any generic depending on the price. I did have to have hip replacement surgery in 07 which left me with foot drop. I also have simliar leg issues going on the left side. My back always kills me and I see a chiropractor. I have terrible joint pain much of the time. After a bone scan, I found out that I am borderline for osteoporosis. I am taking calcium with d and glucosamine. I still need my meds. I die at night without them. Not sure what to do now.

  • MaureenAugust 17, 2010 at 3:40 pm

    I was watching TV acouple of wks ago and an ad came up about people who take nexium are eligible for money from a lawsuit. I have taken Nexium since it was released in Canada and I like many are taking 2 tablets a day. In 1998 I fell and broke my rt wrist in 5 places, and have problems since. Then on Aug 3rd 2009 I fell in my driveway and fracture my elbow so severly that the North Bay Gene[Show More]I was watching TV acouple of wks ago and an ad came up about people who take nexium are eligible for money from a lawsuit. I have taken Nexium since it was released in Canada and I like many are taking 2 tablets a day. In 1998 I fell and broke my rt wrist in 5 places, and have problems since. Then on Aug 3rd 2009 I fell in my driveway and fracture my elbow so severly that the North Bay General Hospital could not repair it. I was air lifted to Ottawa General where I was operated on and it took about 5 hrs and now I have a titanium elbow. I also had alot of problems with the surgery and my recovery. So is there a lawsuit and who do we contact?

  • HaroldAugust 6, 2010 at 7:20 pm

    In 2000 I was diagnosed with Acid Reflux. I was put on Prilosec and after three months the Doctor proformed a endoscope and put me on nexium 40 mg to be taken twice a day. I took It faithfully for three years, The cost was very straining on my bank account( over 180.00 a month) At this time there was no generic brand to sub for it. Started taking it sparingly for the next few years. Over the past [Show More]In 2000 I was diagnosed with Acid Reflux. I was put on Prilosec and after three months the Doctor proformed a endoscope and put me on nexium 40 mg to be taken twice a day. I took It faithfully for three years, The cost was very straining on my bank account( over 180.00 a month) At this time there was no generic brand to sub for it. Started taking it sparingly for the next few years. Over the past few years I have noticed a weekness in my bones, constant back problem, some days it takes a good half hour just to walk upright, I have had my hip go out of joint numerous times and servre aches and pains in my hands, legs, and feet. I was crediting this to the fact that I am getting old, but after reading others stories I am not sure that these drugs are not the reason for my pain.

  • HeatherAugust 5, 2010 at 4:05 am

    I was looking for an explaination for my broken ankle, it should only have been a bad sprain when i discovered all ofl these comments and thought of all the years i have been on Ne3xium and times when it was twice daily...Now i have answers for the other fractures and years of back arm shoulder and leg pain i have had for past 10 years. Thanks and may we all find some relief without side affects w[Show More]I was looking for an explaination for my broken ankle, it should only have been a bad sprain when i discovered all ofl these comments and thought of all the years i have been on Ne3xium and times when it was twice daily...Now i have answers for the other fractures and years of back arm shoulder and leg pain i have had for past 10 years. Thanks and may we all find some relief without side affects which are detrimental to our health and well being.

  • JeffAugust 3, 2010 at 6:42 pm

    I have been on 80 mg of prilosec for two years now and now I have multiple fractures in my spine and Hemangiomas of the spine and osteoporosis which is uncommon in a 43 year old male. I also live with CONSTANT aches during the day and awful Pain at night when I try to go to sleep. I have to take sleep aids and pain meds just to get a half way decent nights sleep.

  • JeffAugust 3, 2010 at 11:57 am

    I have been on 80 mg of prilosec for two years now and now I have multiple fractures in my spine and Hemangiomas of the spine and osteoporosis which is uncommon in a 43 year old male.

  • JanetJuly 23, 2010 at 11:13 pm

    I have been taking genetic Prilosec for about 1 year and out of the blue broke my ankle in 2 places.Dexxa scan indicates a reduction in bone density.I am not on this drug now-after the the fracture I stopped!

  • JenniferJuly 22, 2010 at 3:16 pm

    My 11 year old has been on prilosec for quite some time now. He has fractured 2 two bones in 9 months. I am shocked about the news!!!!!

  • DannielJuly 13, 2010 at 12:10 am

    I have taken Prilosec 20 mg tabs since March 2007 and have experienced several bones fractures in my toes November 2009 and fingers May 2010. I have since had a bone density Dexxa scan indicating a reduction of bone density. Is the use of the Prilosec drug a contributing cause to this condition?

  • jackJuly 10, 2010 at 8:26 pm

    i have been taking prilasec and aciphex for several years and i have had several fractures.ribs,foot.

  • RogerJuly 10, 2010 at 1:50 pm

    I use to brag how I've never spent a day in the hospital in my life. I never broke a bone and still to this day not one cavity. I've always had strong bones and teeth. After taking Nexium and Prilosec for about 8 years or so now at 52-years-old I've lost two teeth that fractured in half, and fractured my L-5 vertabrae. All for no apparent reason. It amazed me how I could fracture my teeth and [Show More]I use to brag how I've never spent a day in the hospital in my life. I never broke a bone and still to this day not one cavity. I've always had strong bones and teeth. After taking Nexium and Prilosec for about 8 years or so now at 52-years-old I've lost two teeth that fractured in half, and fractured my L-5 vertabrae. All for no apparent reason. It amazed me how I could fracture my teeth and my vertabrae without having an event that would have explained it. I was off of work for 4 months. There is no doubt in my mind these PPIs caused this. The only positive thing that came out of all of this is that after being on antobiotics prior to back surgery it cured my stomach acid problem and no longer have to take this stuff.

  • RickyJuly 10, 2010 at 2:36 am

    Durring activation for Desert Sheild/Storm 1990/91 and after wards I experienced Acid Reflux that was so bad It would take my breath away when the acis would get into the esopagus. After returning back to the states I started taking things such as Malox, Rolaids and the such, then one Drill weekend for reserves I got a pain in my chest and my Navy Cheif Corpsman thought I was having a hert attack[Show More]Durring activation for Desert Sheild/Storm 1990/91 and after wards I experienced Acid Reflux that was so bad It would take my breath away when the acis would get into the esopagus. After returning back to the states I started taking things such as Malox, Rolaids and the such, then one Drill weekend for reserves I got a pain in my chest and my Navy Cheif Corpsman thought I was having a hert attack, so they rushed me to emergency room and subsequently determined that I should have an endoscope that revealed severe GERD. I was placed on a diet of low fat foods no coffee, chocolate etc... I was also prescribed Prilosec two times daily. I adhered to this regimine for several years and each time I went without the prilosec I would experience the volcanic type reaction most people have when having an attack. So I stayed on my Prilosec and I thought it was a life saver, then because of my age my new Dr. ecides when I turned 50 to have me do another endoscopy which revealed Barretts esopogus, and I was to maintain the same regimine of twice daily Prilosec, and wath my diet, I subsequenly was diagnosed with Asthma, and coughed all the time, well this year I was diagnosed with Osteoporisis, and through my investigations I found that with a person taking medications such as omeprazole that people could develope this condition, I also came down with bacterial conditions that medications hardly are effective at all. I Got Bronchitis and coughed so hard I fractured a couple of ribs in the process.

  • DavidJuly 9, 2010 at 4:08 pm

    I have had to have 7 discs fuzed together. My bones are "soft". I have DDD. I have taken these meds for about 12 years. I would love to hear of a class action lawsuit due to these companies not saying anything about these effects. I am only 43 and I was informed I can never do my occupation again. I have 19 years invested in my career. What am I supposed to do now???

  • JanetJuly 9, 2010 at 3:57 pm

    I started with Nexium several years ago but it stopped working for me so now am taking Protonix. During the time I was on the Nexium I had a fall and shattered my shoulder ball joint, had that surgically mended. Now I have been on the Protonix for at least two years and have aching hips, both shoulders are sore, degenrative bone soreness in both thumbs and very painful knees. Since I have suffered[Show More]I started with Nexium several years ago but it stopped working for me so now am taking Protonix. During the time I was on the Nexium I had a fall and shattered my shoulder ball joint, had that surgically mended. Now I have been on the Protonix for at least two years and have aching hips, both shoulders are sore, degenrative bone soreness in both thumbs and very painful knees. Since I have suffered from acid reflux for many years and had never found anything that relieved it other than the meds stated, I am wondering what I can do because if I cease the meds the acid reflux returns and if I continue taking them the bone problems will more than likely get worse, this puts me in between a rock and a hard place, damned if you do and damned if you don't I am 60 years old and at an age where bone loss could be an issue without the aid of meds that cause it. Lovely!!!

  • SusanJuly 9, 2010 at 3:47 pm

    My husband has been taking Tagamet for 4 yrs. now after having his gallbladder removed. The surgeon (in another city) told him to take Protonix for 3 months, then quit. His dr. where we live said "well, you need to take Tagamet 300 from now on"---he has and recently broke a bone in his foot and hasn't a clue as to how he did it. He quit Tagamet (which may not be as bad as the others mentioned h[Show More]My husband has been taking Tagamet for 4 yrs. now after having his gallbladder removed. The surgeon (in another city) told him to take Protonix for 3 months, then quit. His dr. where we live said "well, you need to take Tagamet 300 from now on"---he has and recently broke a bone in his foot and hasn't a clue as to how he did it. He quit Tagamet (which may not be as bad as the others mentioned here) today. THANKS FOR THIS INFO!! Oh, and I supposedly have osteoporis but refuse to take ANY of those drugs b/c I suspected they were dangerous, and now we see they cause you to break your tibia or thigh. Ladies, all of those Dexa machines are calabrated differently, and my 38 yr. old daughter was told she had osteoporosis, but DOES NOT! Don't believe everything your dr. tells you!

  • carolJuly 7, 2010 at 6:54 pm

    I have been taking Nexium for at least 8 years if not longer. I had a hip fracture in 2008, that required 2 surgeries and log recover periods (screws and rod put in my hip and thigh). I was only 47 years old. Then in June 2009 I suffered a femur fracture. Another surgery. I am still recovering from these fractures and unable to work. I certain am happy to discover the reason why these fractures oc[Show More]I have been taking Nexium for at least 8 years if not longer. I had a hip fracture in 2008, that required 2 surgeries and log recover periods (screws and rod put in my hip and thigh). I was only 47 years old. Then in June 2009 I suffered a femur fracture. Another surgery. I am still recovering from these fractures and unable to work. I certain am happy to discover the reason why these fractures occurred. But I would be even happier if I could recover the 2 1/2 years of income lost as well.

  • RitaJuly 4, 2010 at 5:21 pm

    I have severe GERD, was feed by feeding the whole year of 2007, I have been on Nexum since 2007. I just got out of the fracture bone cast.I had 3 fractures in my right for no known reason.

  • bettyJune 29, 2010 at 2:39 am

    i was put on prilocet for larengel reflux i switched to over the counter omeprazole DR 20mgm an i took 2 tabs a day i fx my rt wrist both bones in august from a fall then in nov, i steped down from a chair as i was hanging christmas lights fx my left wrist then in feb i knocked the iron off an fx my rt foot i wonder could these fx be the results of this med. or just because i am clumbsy betty

  • sandyJune 23, 2010 at 4:05 pm

    just read the article,after hearing a warning about nexium,I will be stopping nexium immediatly. Iam taking nexium for a small ulcer which is healed now Iif it comes back oh well rather live with a ulcer the broken bones.Thanks for a very informitive article,will be stopping nexium immediatly

  • MatthewJune 16, 2010 at 9:48 pm

    I have been taking prilosec for approx. ten years. I have been diagnosed with osteoporosis due to lack of calcium from taking priolosec. I am 41 and in the last 6 yrs broke my femur,tibia,ulna and my foot. I have had bad back pain for several years.

  • HomerJune 9, 2010 at 10:00 am

    I have been taking prilosec for 6-7 years. I have never broken a bone but I have noticed my bones are stiff at night when I go to bed. I "pop" my ankles, knees and back every night before I can go to sleep. I just thought I was getting old ( 53) but now I realize this started after taking drug. I don't think I can live without it but I have been trying to take it every other day. I wonder if these[Show More]I have been taking prilosec for 6-7 years. I have never broken a bone but I have noticed my bones are stiff at night when I go to bed. I "pop" my ankles, knees and back every night before I can go to sleep. I just thought I was getting old ( 53) but now I realize this started after taking drug. I don't think I can live without it but I have been trying to take it every other day. I wonder if these drug companies are paying the FDA to approve drugs before they are proven safe and why didn't the drug companies warn us before now!!!!

  • grandpa joseJune 8, 2010 at 9:40 pm

    i started taking PPI after i had a 6- bypas -heart surgery in 1998. my dr. prescribed me several of these ppi's one after the other;from prilosec to protonix to nexium to zenegrid and presently to prilosec. i used nexium more or less for 7 years. i've been in pain for years; from lower back, to shoulder, hip, spine, wrists,knees, ankles, but worst of all my BRAIN is in pain now because my doctors [Show More]i started taking PPI after i had a 6- bypas -heart surgery in 1998. my dr. prescribed me several of these ppi's one after the other;from prilosec to protonix to nexium to zenegrid and presently to prilosec. i used nexium more or less for 7 years. i've been in pain for years; from lower back, to shoulder, hip, spine, wrists,knees, ankles, but worst of all my BRAIN is in pain now because my doctors keep on telling me " the pains go with aging", i used to like long -walk exercise for more than 1 hr and treadmill for 30 min everyday but currently i couldn't do this anymore and because of not doing my exercise my blood sugar is starting to rise. i don't have arthritis and i'm not obese and not diabetic and i am positive the pain from my hips, knees, wrists, ankles are due to the side effects of these PPIs.

  • michelleJune 8, 2010 at 2:41 am

    Ive been on prilosec for 4 years and has had 4 fractures in the left leg and 3 possibly 4 in the right leg. Never broke a bone before this.I cant work or walk around for more the 3 hours. It is the worst pain when it comes from the bones

  • MaggieJune 7, 2010 at 1:35 pm

    I have been on nexium for over two years and all of a sudden my teeth are disappearing and Im facing very expensive dental work to even try and save what i have left. Never once did anyone including my doctor advise me that the medication could cause this and if i had any idea i wouldnt have started taking it. My teeth are gone they are over half their size and i cant even talk right , hard to eat[Show More]I have been on nexium for over two years and all of a sudden my teeth are disappearing and Im facing very expensive dental work to even try and save what i have left. Never once did anyone including my doctor advise me that the medication could cause this and if i had any idea i wouldnt have started taking it. My teeth are gone they are over half their size and i cant even talk right , hard to eat and if you look at my teeth you can see the nerve at the top of many teeth. Im so upset finding out just today that it wasnt my acid reflux ity was the medication all along!

  • GerryJune 6, 2010 at 8:39 am

    Been on ppi's for approximately 10 yrs. These drugs long term can cause decalcification of bones ie. hips and spine. Suggest you try to reduce there use by supplementing zantac in pm with lower dose of nexium or prilosac. Zantac doesn't cause the same degree of decalcification. I too, am working on this readjustment. Its not easy because I've gone from sympton free to acid reflux in just a few day[Show More]Been on ppi's for approximately 10 yrs. These drugs long term can cause decalcification of bones ie. hips and spine. Suggest you try to reduce there use by supplementing zantac in pm with lower dose of nexium or prilosac. Zantac doesn't cause the same degree of decalcification. I too, am working on this readjustment. Its not easy because I've gone from sympton free to acid reflux in just a few days.

  • SabrinaJune 5, 2010 at 2:53 am

    I could not believe the television ad when I say it concerning nexium and the other medications for GERD. I have been having problems with my wrist and hip for the klast past two years.I went to see a doctor about them and could not get any resolution.I have also had panic attacks that started about 2years agao...I had been taking Nexium for approx.4-5 yrs.I a have also take the other medication t[Show More]I could not believe the television ad when I say it concerning nexium and the other medications for GERD. I have been having problems with my wrist and hip for the klast past two years.I went to see a doctor about them and could not get any resolution.I have also had panic attacks that started about 2years agao...I had been taking Nexium for approx.4-5 yrs.I a have also take the other medication that they give you for Gast.Refux Disease...when I first tried to come off I was experiencing migranes...my wrist is swollen and no one knows why?

  • BrendaJune 4, 2010 at 4:25 pm

    I have taken prolosec for eight yrs and then had the surgery to fix the gerd. But I have degenerative disc disease and my back also fractured just from bending over. With all my back and neck problems i can no longer work. I'm only 49 yrs old so now i know the problem from all the pain i've been threw.

  • DennisJune 3, 2010 at 11:17 pm

    I been on nexium for 8 or more years,tylenol 4s for 5yers,ankes knees hips back,albows,mussels,ligamants extreme pain.i am pissed

  • rickJune 3, 2010 at 8:17 am

    I have been taking protonix for 5 years since mgb stomach surgery. Last week I fell b y missing last step on 3 ft ladder backwards on soft grass, and fractured my right wrist in two locations. The next day the proton pump inhibitors are suspect...

  • GloriaJune 2, 2010 at 6:29 pm

    Wow, just read this article and you guys are scaring the bejeebies out of me. Have been on Nexium for probably 10+ yrs, have now been told my bones are deteriorating and need Boniva. Tried Fosomax, but could not take because of gastro pain which mimicked heart attack. Scared to take Boniva, but now am scared to keep taking Nexium. I think I am going to try holistic medicine.

  • LynnJune 2, 2010 at 1:58 pm

    I have been on PRILOCET for several years now and was just put on NEXIUM about 2 months ago. Three years ago, i sneezed and it caused two compressed factures in my mid back. I had to have back surgery, called kyphoplasty, which is where they inject the compressed fractures with a kind of "cement". Now, 3 years later, i was in excruciating pain in my upper and lower back and after getting x-rays[Show More]I have been on PRILOCET for several years now and was just put on NEXIUM about 2 months ago. Three years ago, i sneezed and it caused two compressed factures in my mid back. I had to have back surgery, called kyphoplasty, which is where they inject the compressed fractures with a kind of "cement". Now, 3 years later, i was in excruciating pain in my upper and lower back and after getting x-rays two weeks ago, i found out that i have "SEVEN" compressed fractures and i am facing surgery again in less than 2 weeks. I am very disappointed to say the least. Don't know whether to contact an attorney or not? This is a very SERIOUS side effect. And i am the one in so much pain and i am the one who will have to endure more surgery, and MEDICARE AND MEDICAID will be the ones who endure paying for this!!! I am mader than a hornet! How about you?????? Let's get together and have an attorney contact us and see what can be done for compensation. I sure can't get my spine back to where it was, all i can do now is suffer the chronic pain daily and endure more surgery. It's just not fair or ethical. There is a place at the bottom of this page to have an attorney review your comments and contact you. There are only two numbers to put in and then just hit "submit", let's all do this so others won't have to endure the constant pain and the permenent deformity that these drugs have caused. I'm mad as HELL and i'm not going to take it anymore! How about you???????

  • LynnJune 2, 2010 at 1:34 pm

    I have been on PRILOCET for several years now and was just put on NEXIUM about 2 months ago. Three years ago, i sneezed and fractured two vertabra. I had to have back surgery, called kyphoplasty, which is where they inject the compressed fractures with a kind of "cement". Now, 3 years later, i was in excruciating pain in my upper and lower back and after getting x-rays two weeks ago, i found ou[Show More]I have been on PRILOCET for several years now and was just put on NEXIUM about 2 months ago. Three years ago, i sneezed and fractured two vertabra. I had to have back surgery, called kyphoplasty, which is where they inject the compressed fractures with a kind of "cement". Now, 3 years later, i was in excruciating pain in my upper and lower back and after getting x-rays two weeks ago, i found out the i have "SEVEN" compressed fractures and i am facing surgery again in less than 2 weeks. I am very disappointed to say the least. Don't know whether to contact an attorney or not? This is a very SERIOUS side effect. And i am the one in so much pain and i am the one who will have to endure more surgery, and MEDICARE AND MEDICAID

  • JeanJune 1, 2010 at 3:46 pm

    For several years I was taking Prevacid for GERD and then switched to Nexium about 5+ years ago. I am currently recouperating a fractured tibia in my left ankle and for the past 5 or so years I'v had extreme joint pain in both hands. I just heard on TV that these medications cause brittle bones. Is there any class action suit against the manufacturers?

  • MikeMay 30, 2010 at 7:06 pm

    I have been dealing with back pain rt leg pain that goes from my hip to my knee been getting worse for about 2years until i can barely walk now.First the doctors thought it was a disc problem tried different fixes nothing helped i said it feels like my leg is slowly deterorating now they say my hip is the problem the socket has holes forming in the bone.I have been taking nexium for 7-8years not k[Show More]I have been dealing with back pain rt leg pain that goes from my hip to my knee been getting worse for about 2years until i can barely walk now.First the doctors thought it was a disc problem tried different fixes nothing helped i said it feels like my leg is slowly deterorating now they say my hip is the problem the socket has holes forming in the bone.I have been taking nexium for 7-8years not knowing until now that its probably been causing my pain everwhere.

  • mobMay 30, 2010 at 1:25 am

    I took protonix for 5 years, had to get tmj surgery, fractured about 4 fingers for soft hits. This is ridiculous, I though it was just me, now looks like it was that stupid pill. I'm on Nexium now and don't feel any better.

  • sandraMay 29, 2010 at 11:20 am

    I have been on prevacid close to 10 years, without it I will feel the burning in my throat and the acid backup is terrible! I always had some concerns about being on it for so long of period. what else is left other than suffer,I don't want to do that!

  • jeffMay 29, 2010 at 2:01 am

    '= have taken Prilosec OTC. Joints and hip and back pain now all of a sudden...is there a class action suit or something that can be done 2 this company for the bilss incured?

  • JimMay 28, 2010 at 8:10 pm

    I've been on PPI's for over 10 years. I am 52. I have developed cervial stenosis. I have had lower back surgury. In the last 3 years I have been experiencing debilitating pain in my mid back. I recently had an X-ray on my back and the Doctor said I have a back of a man in his 70's Today I went to get my Protonix refilled and the Pharmacast told me about the new findings of taking this drug l[Show More]I've been on PPI's for over 10 years. I am 52. I have developed cervial stenosis. I have had lower back surgury. In the last 3 years I have been experiencing debilitating pain in my mid back. I recently had an X-ray on my back and the Doctor said I have a back of a man in his 70's Today I went to get my Protonix refilled and the Pharmacast told me about the new findings of taking this drug long term.

  • JohnMay 28, 2010 at 2:15 pm

    I have been taking Prilosec for 15 plus years, first as a prescription & then OTC once it went in that direction for my acid reflux. I encountered a C-5 fracture, denerative disc disease, and have had severe lower back pain which required back surgery, fusion on my lower 2 disc. I am in constant pain which requires me to take pain meds daily. I have refrained from taking the Prilosec, whic[Show More]I have been taking Prilosec for 15 plus years, first as a prescription & then OTC once it went in that direction for my acid reflux. I encountered a C-5 fracture, denerative disc disease, and have had severe lower back pain which required back surgery, fusion on my lower 2 disc. I am in constant pain which requires me to take pain meds daily. I have refrained from taking the Prilosec, which results in heart burn, another pain that I now deal with since this new information has arrised. We are now all puppets of the zare drug companies and are all reaping the reprucusions of the lack of responsibility they take. Why did it take over 15 years for the drug companies to realize this threat?

  • MattMay 28, 2010 at 9:26 am

    I have also taken almost all of the listed brands for about 15 years. I started with the perscribed and switched to the OTC brands when I found they were basicly the same as the perscribed and cheeper. Any who, I have never had problems with fractures but I do suffer from major joint and bone pain. With that said, I do take Tums with calciam like they are candy during the time I am out of the OTC[Show More]I have also taken almost all of the listed brands for about 15 years. I started with the perscribed and switched to the OTC brands when I found they were basicly the same as the perscribed and cheeper. Any who, I have never had problems with fractures but I do suffer from major joint and bone pain. With that said, I do take Tums with calciam like they are candy during the time I am out of the OTC type. I am woundering if this is putting me at a lower risk???

  • dawnMay 28, 2010 at 5:49 am

    So which is worse...the fractured bones or Barrett's Esophageal Cancer? My dr. told me I had to take something to avoid that.

  • SusanMay 27, 2010 at 4:53 pm

    I have taken 2 Prilosec OTC a dau for 3 years to treat GERD and I found out last week that I have a compression fracture in my lower back. My tailbone has also been hurting since January. I haven't injured myself. I am 3/4" shorter than I used to be. I am 43 years old! I just heard on tv that Prilosec causes this. Is there a lawsuit against the makers of Prilosec OTC?

  • DebiMay 27, 2010 at 2:00 pm

    I take Nexium two times daily. In the last 2 years I have had 2 wrist fxs and a fractured vertabre in my back..I had never had a broken bone before then and I am 52 yrs old..Now I am scared to take it and scared not to...

  • pamelaMay 27, 2010 at 1:32 am

    I have taken these medications for years & have had many fractures & breaks in bones and this is the first I have ever heard that these medications could be responsible for this.This is totally amazing!!!!!

  • KeIlyMay 26, 2010 at 10:47 pm

    I have been taking Prilosec everyday for at least the last 10 years, Everytime I attempted to not take the medicine, I had extreme bouts of nighttime burning choking incidents that brought me to go back on the medicine to stop these nighttime scares and pain. I have always advised my doctors that I take this medicine and they have never given me any advice or concern as for me taking this on a d[Show More]I have been taking Prilosec everyday for at least the last 10 years, Everytime I attempted to not take the medicine, I had extreme bouts of nighttime burning choking incidents that brought me to go back on the medicine to stop these nighttime scares and pain. I have always advised my doctors that I take this medicine and they have never given me any advice or concern as for me taking this on a daily basis. The scare of waking up in the middle of the night choking and not being able to catch my breath, along with the extreme burning of the acid in my throat is something I want to avoid.

  • SheliaMay 26, 2010 at 10:30 pm

    My mother-in-law is having very serious issues with bone fractures. She has been on these types of medicatiions for over 5 years or more. She has numerous fractures in her spine, ankles and wrist. What can we do? The phycicians cannot treat her fractures with cast because her bones are not strong enough to endure the pressure from the cast. She is in a bad situation due to these medications. What [Show More]My mother-in-law is having very serious issues with bone fractures. She has been on these types of medicatiions for over 5 years or more. She has numerous fractures in her spine, ankles and wrist. What can we do? The phycicians cannot treat her fractures with cast because her bones are not strong enough to endure the pressure from the cast. She is in a bad situation due to these medications. What a shame!

  • DonnaMay 26, 2010 at 4:06 pm

    I have been on medication for Gerd for probably over 15 years. Started with prevacid, and currently on Nexium. I have cervical spondylosis and denerative disc disease. (I have also had 3 fractures in my left foot) Lost a disc about 4 years ago(boy did that hurt). I always thought it could be my anti-seizure med. But now I see this against the heartburn drugs!! I have been in pain for many years!!

Share Your Comments

I authorize the above comments be posted on this page*

Want your comments reviewed by a lawyer?

To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.

NOTE: Providing information for review by an attorney does not form an attorney-client relationship.

This field is for validation purposes and should be left unchanged.

More Top Stories