Enbrel Lawsuits

The arthritis drug Enbrel has been linked to an increased risk of fatal infections, incluing tuberculosis and fungal infections. In May 2008, a “black box” warning was added about the risk of tuberculosis. In September 2008, the FDA added information to the “black box” warning about the risk of potentially fatal fungal infections, which were often going undiagnosed.

STATUS OF ENBREL LAWSUITS: Potential for legal claims are being evaluated for individuals diagnosed with tuberculosis before May 1, 2008 or who died as a result of an infection.

MANUFACTURERS: Amgen, Inc. and Wyeth

OVERVIEW: Enbrel (etanercept) is a Tumor Necrosis Factor (TNF) Blocker, which was approved in 1998 to treat various auto immune disorders, such as Crohn’s disease, rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis and juvenile idopathic arthritis (previously known as juvenile rheumatoid arthritis). It is administered as an injection given either by the user or a caregiver.

There are three other TNF blockers currently approved in the United States, Remicade, Humira and Cimzia. When all uses are considered, including indications that Remicade is not approved for, Enbrel is the most widely useed TNF blocker.

ENBREL TUBERCULOSIS RISK: In May 1999, information was added to the warning label about a possible risk of serious infections, including sepsis, which has caused a number of deaths. In April 2008, this information was added to a “black box” which was more prominently displayed on the label.

The “black box” warning also included information about cases of tuberculosis associated with use of Enbrel injections. The FDA and manufacturers indicated that healthcare providers should screen their patients for latent tuberculosis before prescribing Enbrel.

Tuberculosis, also known as tubercle bacillus or TB, is a deadly infection which commonly attacks the lungs (pulmonary TB), the central nervous system, circulatory system, bones, joints or the skin.

Symptoms of tuberculosis could include:

  • Chest Pain
  • Coughing Blood
  • Fever, Chills or Night Sweats
  • Appetite Loss or Weight Loss
  • Fatique

ENBREL CANCER SIDE EFFECTS: In June 2008, the FDA released an early communication about an ongoing safety review involving Enbrel and a possible association with the development of lymphoma and other cancers among children and young adults and an Enbrel black box cancer warning was added in August 2009.

At least 30 reports of childhood cancer were received by the FDA involving the use of TNF blockers. Other medications indicated in this early communication were Humira and Remicade.

Approximately half of the cancers seen in all children and young adults taking TNF blockers were lymphomas, including bother Hodgkin’s and non-Hodgkin’s lymphoma, which is a cancer of cells in the immune system. Lymphoma is not a recognized complication of JIA (Juvenile Idiopathic Arthritis) or of Crohn’s disease. Other cancers reported included leukemia, melanoma and solid organ cancers.

ENBRAL FUNGAL INFECTIONS: A number of users who were receiving TNF blockers, such as Enbrel, have experienced fungal infections, such as histoplasmosis, blastomycosis and cocciioidmycosis. In several of these cases the infection resulted in death.

In September 2008, the FDA issued an alert to healthcare providers to provide new information about the risk of Enbrel fungal infections. At that time the agency also indicated that new information will be added to the Enbrel black box warning to ensure that doctors and consumers are aware of the risk, especially for those who live in or visit areas where fungus is prevalent.

Unfortunately, many cases of fungal infections from Enbrel go undiagnosed by doctors, since the symptoms are similar to the flu. Symptoms could include cough, fever, fatigue, loss of weight, sweating and shortness of breath.

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  1. Matt Reply

    My father Paul M. Vaughan MD, MPH age 63 died in April of 2014 from Advanced Mucinous Adenocarinoma of the lungs….. The man never smoked a cigarette in his life and began taking Enbrel 2 years ago for his Rheumatoid Arthritis. This drug is pure poison and should be taken off the market. The man stood no chance and living in Pittsburgh surrounded by the Best Doctors in The World he was left with no cure for this extremely rare 1 of 3 reported cases in the Pittsburgh region over the last 25 years. To say these risks are minimal or rare maybe a nice way of saying we don’t care about the people taking this drug, I just need my Corporate Jet washed before I leave for Dubi. The case studies on this drug I believe are flawed. The statistics for Malignancy make no sense when you read all of the above stories of fatal out comes from this drug. And to think Phillip Morris is not allowed to advertise smoking but Enbrel can advertise a death sentence is ridicules. My father made sure his Rheumatologist performed all the proper tests before being prescribed this medication, alongside using the statistics given by Enbrel to analyze the risk of Malignancy and fell remarkably short of a cure, and most certainly lead him to an early death. Maybe if Phil passes away tragically, which I prey to god not, we may see some justice for All of the above. Big Pharma has a Big Fucking Problem and I will be damned if I let this go.

  2. ivy Reply

    I’ve been hearing the commercial for enbrel and never really noticed what the side effects was until my mom passed from pancreatic cancer. My mom was always, faithfuly going to the Dr for check UPS. The only thing she had was the psoriasis and was prescribed this shot. Literally she went from healthy to deathly ill over night. Was first told after many test they were unsure what she had. Then after going to Cooper the cancer was discovered but it was to late. She already was at stage 4. She was diagnosed September 2012 and passed April 3013. I’m so sick of these Dr prescribing meds and not telling you the whole story all the side effects. If i knew i was going to lose my mom from this i would have never aloud her to take this shot

  3. Gary Reply

    My wife was diagnosed with RA. In May of 1999 were went to Duke University for treatment, at the time she was started on Enbrel. We did not know much about the drug and it did help for a couple of months. But in July 1999 she was admitted to UAb in Birmingham, Al. Hosp., where she lay in a coma and on life support for 69 days and nights. Finally it became to much for her and she passed on Sept. 29. It was was not until years later that the potential for this type of death came to my attention. Is it to late to file a lawsuit against Enbrel she suffered for 69 days.

  4. Ronald Reply

    My wife took Embrel for along time and got non small cell lung cancer in July 2014, and passed away on January 14, 2015.

  5. Debby Reply

    Regarding death of my daughter dx with Legionella Pneumonia 12/30/13 while taking Enbrel. She was a healthy 32 yr old female body builder. Presented at Allen Presby Hosp Er with complaints of Flu like symptoms. She questioned ER Dr. regarding Enbrel Injection due that evening. Was intstructed by ER Dr. to continue injections and was found 24 hrs later unresponsive. All staff at Presby ICU was shocked at her untimely death due to current state of well fittness. I informed all her attending Phys of the event in their ER but was ignored I’m sure due to liability. This has been an extremely difficult year. Her death should have been investigated more throughly by Allen Presby at Allen Tx. I can’t help but believe that they were more concerned about the legal ramifications regarding that ER visit.

  6. David Reply

    I am a fast track patient with Enbrel who has been rudely ripped away from the drug. My understanding that after the drug was sold in Amgen that the ingredients were slightly changed. I have not had a chance to confirmed yet but I will in time. Some even go far as too say that it is nothing more than cocaine. I disagree. I am suffering from a rare form of rheumatoid arthritis. No drug is perfect and physicians are only practicing. Patients have so undiagnosed problems often researchers and physicians miss most often by poorly trained lab workers. Enbrel is a modern day drug and in my opinion still too new to criticize the problems. Everyone who takes drugs as far as know are warned about the potential side effects. better to try than just roll over and play day. I was sad to see immune who created the drug sell it. Big business bought the drug and lots of patients, many of us younger, I was 37 when I went on the drug will lose for what we went on the drug for.

    I am sorry for the loss of life for many who wish to blame Enbrel. we can only hope the FDA and other government scrutinizing agency will take long look into the overall performance of the drug on a variety of illnesses before eliminating Enbrel from the market.

  7. Laura Reply

    I took embrel for 2 yes I started having chest pains an breathing problems ..test after test results where a growth in lung …I also started having Brown crusty spots break out all over my body ….. My lung is still being watched to make sure the its not cancer growing inside my lung….the groth in my lung is on the artery that supplies oxgen to my heart…..with ra as you know the immune system is weak already so when I catch cold it feels like I’m dying from heart attack…… Ahghhhggggg …..can’t win for losing….

  8. Lillian Reply

    I went back on Enbrel after a few years it worked miracles the first time around.I was off it for 5 yrs I guess,And this past Feb 2015 I tried the humara I only did 3 shots and stopped cause i was getting an unusual pain in my side of my hip,who knows if that was even connected to the Humara? So I went on Enbrel again May 2015 took it for 6 weeks. had the blood tests done and no TB But Found out that my kidneys got lupus from the Enbrel my blood test never showed any signs of Lupus. did renal biopsy on me sent out to be read and they said the enbrel gave me lupus in my kidneys..I’m very scared I didn’t realiize how much your kidneys function.I was in hospital for 3weeks all kinds of testing ,had to go around robins roost to take test because there are tests you cannot take no contrast or dye when your kidneys aren’t working correctly I was told by my Kidney Doc that I’m one of the 5 cases that got Lupus in my Kidneys from Enbrel and that they are just practicing medicine on me because they don’t have answers on how to treat it.I’m taking kidney meds to help break down what ever enters my kidneys with every meal, I was filled with 25 extra pounds of fluid when they released me from hospital its has been 4 weeks I can see my ankles again.They had to give me high dose predisone everyday it is going to take months of treatment monitering blood work for my kidney levels. Water pills to release all this fluid that built up..I’m on a no sodium diet and I’m only allowed a certain amout of liguid for the day.I cannot afford all the testing doctors office copays I think Enbrel you man up and take care of the damage their drug has caused me own it.I want to Sue them.I dn’t want to loose my home over medical bills.I think Enbrel is responsable and they should pay. I’m a deeply sorry for those who have lost a loved one because of this drug..God Bless..

  9. Ruby Reply

    My disabled veteran and now deceased husband first used Bextra for over two years and his RA got worst. He was then put on Enbrel and went downhill from there. Several calls were made to the Enbrel hotline about what to do. He was always told to stop taking the Enbrel meds but not longer than two days and to continue taking them. Each time he was told to see his RA doctor, which he did. Colds, chills, fevers, skin discolorations and burn-like discolorations of skin on his back, pains, swelling of joints, and finally, a horrible death of not being able to breath. Upon contact several contacts with Pfizer after getting their letter to discontinue use of the Bextra I was told that there were no lawsuits being considered for the state of Tennessee. I requested if any lawsuits comes up, I wanted to add my husband, Carliss E. Middlebrooks’ name to their roster. Upon contacting several internet lawyers – no avail. I write these comments because I feel so bad I could get no justice for my husband after being feed both Bextra and Enbrel over a span of approximately 5 years. One of the prognosis was the “Steven Jeorge” syndrome – fully documented in his VA/RA doctor’s file. When you are poor with no access to expensive legal services,nor can not afford the services, and the powers that be knows that you can do nothing, then you you have been forced to fail in your trying. My husband died in 2005 one day before his 55th birthday, leaving me with two sons (ages 18 and 16 in school) to raise. Both Enbrel and Bextra should have compensated each user of it deadly products. But for me and/or those who have no power, than you for at least letting me vent.

  10. Cheryl Reply

    2013 I filled out a form regarding joining a class action suite for Enbrel.
    I haven’t rc’d anything response.

    I had a shot of Enbrel 2-2012, within 10 Hours I was in the ER with my kidneys failing, liver
    Shutting down and my blood count was 4. Taken by ambulance to Covent Hospital
    Put on dialysis for 3 months and in the hospital for 5 weeks.
    Blood transfusions, terrible bout with diarrhea, in diapers, just very hemiliatiting.
    My life was hanging for 48 hrs in the ICU.
    My husband had to drive many miles to visit me .

  11. Frances Reply

    I am a 68 year old women. I have had RA since I was a teenager. I have been on the drug Enbrel for over 10 years. In May of this year it was discovered that I had a carcinoid tumor ,quite large in the top lobe of my right lung. It effected two of the lymph modes. IT continued to worsen. Sept 11,2015 I was admitted to the hospital in Dallas Tx. After 2 weeks I had a surgery removing the top 1/3 of the right lung and 5 lymph nodes. It was a carcinoid tumor. I am at home now. I feel that the drug company should be more responsible about the drugs they sell to the public, or they should be liable for the problems they cause, and the financial problems it causes for families.

  12. Lorraine Reply

    I am a 44-year-old and I’ve been on Enbel for over 10 years for psoriatic arthritis. Recently diagnosed with lung cancer requiring removal of right upper lobe of my lung

  13. Sally Reply

    I took Enbrel right after for my RA. After on Enbrel for years in got the side effect Hogkin lymphoma 2009. After a year of chemo I ended up with painful nerve damage from my knees down. Savings were gone fighing this and on going medical bills and pain killers just to be able to walk are expensive.

  14. Barry Reply

    In 2012 I was diagnosed with an ADEM caused by Embril. My Brain swelled and I almost died.I tried for 3 years to sue them but it is hard. I met some people along the way that had bad experences with the drug, one lady went blind as it attacks the optic nerve, Good luck with your lawsuit.

  15. AUDREY Reply

    I took Enbrel for 2 years developed Amyloidosis, when though years of being a very sick woman finally ending up having a stem cell transplant, now wear a pacemaker and def. because of the damage it has done to my heart.. am a very lady lucky to be alive. I think that my illness should have some compaction from the company that made the horrible medication.

  16. T?B. Reply

    If you wouldn’t mind sharing, why was your daughter given Enbril? My husband has a horrible case of psoriatic arthritis and has had zero relief from Methotrexate. His sister has done relatively well (so far) on Enbril. After reading this blog, we are not willing to gamble his life. Thank you all. It must be incredibily painful for you to share; it is certainly painful to read.

  17. DS Chicago Reply

    My wife and I were married for over 25 years but once she started taking enbrel she got relief from arthritis but she also had tremendous changes in personality. None of our family wishes to deal with her. It’s been sad. She told me her thyroid is destroyed. Anyone see this occurring after taking it? My marriage is now done. Sad.

  18. Fran Reply

    How do you reply to some one on the above list. I would like to reply to Lorraine, from Oct 9, 2015.

  19. Ruby Reply

    See below. I want to join any class action law suit that might be in the works as it regards Enbrel.

  20. Donna Reply

    I have Rheumatoid Arthritis and have been taking Enbrel for over 12 years now. Have NEVER felt like it has helped a lot with the pain I experience, but now I have Cysts on my Pancreas and Chronic Pancreatitis. I just had a Biopsy of the fluid inside the cysts to check for Cancer. Will not receive results for at least one week. I feel the Enbrel is the cause of my health problems.

  21. amanda Reply

    ive been on enbrel for a month and ive gotten sick EVERYTIME i take my shots, the night of my shots i get sick, goes into the next day. im so sick right now. my stomach hurts so much, i feel nauseous, my forehead feels on fire, i cant eat. never hungry. i hate enbrel. gonna call my rheumatologist tomorrow and tell him im done with the biologic drugs, methotrexate did not work, not gonna be a guinea pig no more. my husband went to store for chicken soap. im so sick.

  22. Raymond Reply

    I have been taking embryo for two months just this weekend I have experienced drop foot
    Just wondering if any other patients have experienced this?

  23. Terrie Reply

    My husband has been on Embrel now for over 5 years. We just got the results of his skin biopsy and he has a rare form of non-Hodgkin’s lymphoma on his head. We are just starting the process of cancer staging. His dermatologist took him off the Embrel and stated that they believe it is the cause of this rare cancer. He has been faithfully doing his labs and check ups. I’m sickened by the fact that the manufacturer of this drug hasn’t warned people that taking this drug might kill them with strange/rare forms of cancer. It’s not okay to sell something as a medication when the adverse reactions/side effects are worse than the illness. We don’t know his prognosis yet. I’m praying that I don’t lose my best friend. He was receiving treatment for AS (ankylosing spondylitis).

  24. Linda Reply

    I’ve taken Enbrel off and on for about a year now. I have RA and in the past was diagnosed with SLE and Sjogren’s Syndrome. The first time I took Enbrel, I developed pneumonia approximately one month after taking my first shot. I spent a week in the hospital and was so scared that I was going to die, I swore off this and all other drugs like it. However, the crippling pain of RA resurfaced and after a failed three month run on Simponi Aria, I returned to Enbrel. For close to six months now I’ve been in and out of the hospital, to surgeons, and to breast cancer specialists for a tumor in my milk duct, breast pain and swelling, and bleeding from my nipple. Just got news that there’s no cancer present (after surgery which has left me with a three inch long scar and loss of sensation). Took my first shot today after two months off (was in sooo much pain from uncontrolled RA) and breast started hurting almost immediately. Also, I am guessing I gained ten to fifteen pounds in water weight and I have puffiness around my eyes…worried about kidneys now. And tonight, I’m wheezing. Feel terrible. Very dangerous drug.

  25. Terry Reply

    My names terry just a to give people a Waring about taking enbrel I took it for around 9 months and I ended up seriously ill in hospital with liver failure I was put on the organ list for a new liver I asked for a liver biopsy and the results from this came back as drug induced liver failure I nearly lost my life I just want people to be aware of how serious a drug enbrel is and it can cause serious infections be carefull any one using this drug word of advice don’t take it.

  26. Michael Reply

    I was on the original drug study for Enbrel in April 2000 and taken off in December 2000, because my hands and feet were tingling or asleep. The rheumatologist said nothing about the side effects. I immediately had an MRI, went to the Mayo clinic and UT Southwestern in Dallas. Sure enough it caused or exacerbated MS. Then, caused severe depression where I pleaded to take my life. This drug causes horrible side effects unknown by the patient. I originally took it for RA and psoriasis.

  27. JOHN Reply

    Not long after my FIRST injection of Enbrel, I started getting joint swelling in my ankle the size of a golf ball. Then the veins in my arms turned RED and my arms were painful. My spinal pain was NOT relieved at all. I notified my Rh. and she was shocked by the reaction I had and notified NIH and FDA. I never had another dose of this FAMILY of drug again. I just started CBD cream on my hands and it is a miracle relief.

  28. Kevin Reply

    It’s horrible to read all the deaths associated to this drug. I can’t believe this is still being prescribed. I was just prescribed this and will not start. I’m 38 and have Psoriatic Arthritis.

  29. Dana Reply

    My mother thought- we ALL thought- Enbrel was the answer to her prayers. Her incredible pain due and progressive damage due to RA literally stopped in it’s tracks.
    Not three years later she was found to have stage 4 ovarian cancer. All genetic tests for cancer genes were negative. All of them. Her injections were regularly in her abdomen area.
    Before she died, we talked about what risks people take in order to stop chronic pain. She said the didn’t think twice about the black box warning. Now she was most likely dying well before she would have. We’ll never know, but it’s a good guess. Even her oncologists agree. There are ways to manage RA without dying. It is an awful, painful way to live. Living with cancer is an even worse. She firmly believed she injected into herself- that she gave herself cancer while stopping the RA. She said if she had to do it over again? Oh my gosh. No. No, Enbrel. Please dear people, think long and hard about using this drug. If life is truly unbearable, if you would rather be dead than live with the pain you’re in- well, that’s horrific and I am truly sorry. My family, my mother’s doctors- everyone she’s spoken to about this believes it’s a ticket to death. You’ve simply got to weigh whether or not your life has gotten to the point where it’s not worth living. Then and ONLY then should you take this poison. That’s what it is- poison. Best of luck. I’m so sorry for everyone’s losses that I’ve read about here. Know there are others who feel your great sorrow.

  30. Dominique Reply

    I have Psoriatic Arthritis and began on a treatment of Humira which after a year no longer worked. I was given Enbrel which helped a great deal with the relief of pain and swelling of joints. After a year on the medication I began having abdomen pain and my pain came back with the swelling of joints. I felt as if I had a bladder infection which I have never had. Went to a Urgent Care and sure enough was diagnosed with a Bladder Infection. After a week with no relief I sought the help of a Urologist. Who very quickly scheduled me for a Cystoscopy and there it was Bladder Cancer. The reason of my bladder infection was due to the stalk of the tumor had blocked and pertruded from my uretha out of my body. I was immediately scheduled for surgery to remove the tumor and a month later was scheduled for a complete Hysterectomy. At the time of the Hysterectomy a Bladder Sling was put in place to help my bladder. Within months the Bladder Sling broke and embedded into my Bladder. I am 4 years into Bladder Cancer and have to have a Cystoscopy every 3 months due to having high grade Carcinoma. Went I went to see my RA doctor and told him when I was first diagnosed with Bladder Cancer was told to immediately stop the Enbrel. I have never been followed up by my RA doctor, never. I suffer great pain every day and have had 5 major surgeries due to my Bladder Cancer. On my last visit my Urologist seems to think a new growth is beginning. I have taken the BCG treatments which nearly brought me to my knees. Never was I informed of the possibility of any Cancer from Enbrel. Today its the fight of my life.

  31. Kenia Reply

    Start using Embrel on February 2018, few weeks later feel sick, call my Dr. tell my Dr. Embrel is not working for me. Got sick again , call her she tell me that I need to give a chance to Embrel, I believe her , I decided to continue until November 2018, I don’t know why I listen to her, when she never wants to listen to me,, in January 2019 pneumonia, very sick, I’ll get better , in May same symptoms again, in October a pain in my left side, Lung cancer, “. 3 months today that I had my sergury!!! Please do not used Embrel, this medication is very dangerous, I don’t have no idea about all this side affects!!! If I know what I know now I will never use this medication. First flu symptoms, stiffness, fatigue, exhausted like never before, my feet and part of my face swelling, my eyes, I’m 57 years old female only with Rheumatoid arthritis and high blood pressure, never smoke in my life now we all this sickness!!! Please read before you used any of this medication..

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