I took Prilosec and had OD symptoms even though I was on a regular dose. I was on 20mg a day. Keep in mind after these symptoms I just got medicated for the symptoms. They kept upping the dose.

No one thought the medicine could do this. Now I have been off for 4 months and am still sick. My life has fallen apart. I was supposed to get married this summer.

I am 24 years old, and was healthy before all of this.

Symptoms were:

* confusion
* drowsiness
* blurred vision
* fast or pounding heartbeat
* nausea
* vomiting
* sweating
* flushing (feeling of warmth)
* full feeling in my head
* dry mouth, very thirsty

I also experienced:

* constipation
* dizziness
* tooth and gum decay and pain
* left upper back/shoulder pain
* severe stomach cramps
* rash
* itching all over my body, mainly chest and arms
* my feet and ankles were swollen
* difficulty breathing
* muscle spasms,
* tingling in my face, lips, and limbs

I have 8 stents in my heart and was on plavex and prilosec since 2004. I had constant severe chest pain, dizziness and weakness for 5 years. I had 3 stents in 2004, 3 stents 6 months later, then 1 and 1 6 months apart. Every time i left the hospital they told me how great i was going to feel. Not even close. It was hell. Recently my wife and i saw a tv special on taking the 2 together and the danger involved. Since then i contacted my Dr. and all hell broke loose. Since i am no longer taking prilosec with the plavex all the chest pains and other sym toms are gone.

yes i have been on prilosec for about 8 or 9 years and i started having symptoms like dizzy ness ,tingling in face ,hands,and feet as well as nausea,it is been said that it blocks the absorbtion of b 12 among other side effects, if i dont get better i will contact a lawyer and follow with a lawsuit this drug is mis leading , as well as there patent that expired in 2001 and they complained about revenue loss since it is the most prescribed madicine,just wait there will be a class action suit against them and the will have to give up there millions of dollars to the public this is not over yet

If it’s true about the Prilosec and Plavix combo killing people why arent doctors telling thier patients about it? My doctor just “poo=pooed” it when I asked him!

I have 7 stents in my in my heart. Installed 2004 to 2007. I started taking Prilosec in 1996 and Plavix in 2004. I never felt any bad effects of Plavix +Prilosec.
But last month my cardiologist told me not push our luck and replaced Plavix with Zantac. I am changing my eating habits to somehow manage with Zantac. For hearttburn/reflux Zantac is nowhere as effective as Prilosec. (Aug. 20, 2009)

My 88 year old mom has been taking plavix for years and years w/no side effects. In April, she was told she needed to start taking prilosec because she had a zenker’s pouch (in her esophogus), even though she has never had any heartburn. Well, 3 weeks ago she had a massive stroke (a “dry” stroke caused by blockage). Could the prilosec have made her plavix so much less effective that she had this stroke? She was in excellent health before the stroke — taking 3 classes a semester @ college, etc.

I had a massive heart attach at 54 in 2006 and my life was saved within 30 mins by 3 stents even though I never had high blood pressure, a bad lipid profile, diabetes or other factors. Because of the emergency situation I could not be transported to a hospital for the medicated stents, but I do have the unmedicated stents. Before my heart attach I had been taken Prilosec OTC for my GERD with amazing success. Nothing gives me heartburn anymore. After hearing about this, and reading this FDA article, I’m quite nervous about continuing with Prilosec and will immediately switch to one of the recommended other antiacids remedies, hopefully it will work as well. Even after my cardiologist wanted to take me off Plavix we decided to keep me on the med due to discovery of PAD. After reading this article I feel now maybe my blurred vision, numbness in limbs and shoulder/neck pain maybe be elevated, we will see

My Mom was on both Plavix and Prilosec for about 2 years. She woke up one day completely confused and basically just “not really there”. She was admitted into the ICU and passed 3 weeks later. They never figured out what happened to her and she was in one of the top 5 hospitals in the country. She tested fine for EVERYTHING. After reading this, i wonder if this was the reason. i wish i had an answer because it weighs on me everyday.

My mother-in-law just passed away after a sudden onset of chest pain diagnosed as a ruptured hiatal hernia( she did not survive the surgery to repair this). She had a history of surgery for the hiatal hernia over 10 years ago and had no recent symptoms of GERD, but had been switched from coumadin to Plavix over 6 months ago (she also had a pacemaker placement about 3 years ago).
I dont think she was on anything for GERD.
The surgeon who tried to do the the repair of her acute ruptured hiatal hernia said her “stomach was a mess” I’m wondering if she should had been on therapy with a PPI or at least have been followed for her GERD/hiatal hernia condition.
She had been in nursing homes for past 2-3 years and it seemed that her medical records had not followed her and her long-standing medical history was ignored by nursing home physicians. In fact, she went from the nursing home to the ER twice and the 2nd time if her son had not insisted they provided a diagnosis he wouldn’t allow her to be sent back to the nursing home. It was at this time he had to tell the ER staff to check her records from the nursing home for history of GERD surgery. Only then did they do the scan that gave her fatal diagnosis.

Unknowing, as I never thought it was an issue and never told my Cardio, I’ve been on Plavix and Prilosec OTC for several years ….years I’ve also gotten 4 stents and had two native grafts collapse. When I first heard about the possible conflict a few months ago, I stopped my prilosec. My Cardio always told me, “never miss a dose of Plavix.” Now my acid is so strong I choke when I eat. Until now I didn’t know that Zantac or Pepcid were good alternatives. I’ll start using them and let my cardio know on next visit. THANKS!

i have six stents snd have been on omerprazoile for over 3yrs 2x a day. with plavix.i am always having chest pains that nitro does not relieve. my dr keeps passing it off as not heart releated. ten weeks ago after a stress test i was admitted to hospital and had another stent implanted. never relieved my chest pains.
ten days after the stents i reaadmitted to hospitol after to days of testin i was released with no results for chest pains other than dont take omerprazoile and it resuced the effect of plavix by 25%. no mention of any side affects other than that. am home now with chest pains and confusion.

I am 36 years old and I just got home from the hospital due to having a heart attack. I have one stent, one artery completely blocked and one 60 percent blocked. I am not overweight, i exercise and eat fairly well. I have been taking prilosec for about 3 years now. Since, i have been put on plavix and have been taken off prilosec. Doctor has never explained why, so I have been doing research. My acid reflux has come back and I am needing an alternative, over the counter, prescription, or home remedy. Also wanted to know if pepcid, zantac, etc. was ok to take.

i am currently taking omeprazole for my stomach and i am having bad side effects and wanted to see if there is a class action lawsuit on this medication .

I have had alot of same symptoms as colleen as well as a break in a bone just last month. I do want an attorney to contact me. I cannot go to a doctor we live paycheck to paycheck and I cannot afford any more doctor bills the break caused me over 4k in bills so I’m kinda screwed right now behind in rent and everything due to this.

Hello my friends, I’m in the boat with you all. 9 stents 1 double bypass and 1 heart attack. I was on 40mg of Prilosec with no problems but saw on the idiot tube the information about the problems mixing both prilosec and plavix. You have to wonder, Why all of us have GR of the stomach. Could it be our food we buy? We all know the FDA and Pharmaceutical Co: profit about 260 billion dollars a year from the sales. It’s rare to find a Doctor who deals with the whole person these days. I do not have one of these, but am looking. I feel our best defense is our own research, asking question’s, challenging some of the Medicines. For God’s sake it is not normal to put something into our bodies that has all those side effects. Does it make sense to you? In closing I have had 29 operations since childhood and have dealt with the Medical Community since then. I do not trust what I hear, until I investigate and get 1-2-3 opinions at least. Good luck to us all. And God Bless. Your Brother Charlie

I’ve been taking prilosec 20 mg. for the past 10 years. II’ve lived with light headed, dizzyness for quite a few years. doctors tell me to drink more water since I like to workout, thinking it’s dehydration. In the last year and a half I’ve had significant nerve issues with my hans. Tingling andmuslce spasms. Been to many doctors, they all said it’s fine to continue prilosec. I’m stopping as of now. I’m pretty worried of what damage could be done, taking this for a decade. Hopefull it’s reversable.

I had one stent put in my decending artery in March of 09. My Cardio Doctor prescribed plavix. I had been on prilosec for years. A few months later in August of 09, I had two more stents put in the same artery. Still on both drugs, I began having pain and preasure and lack of strength again and an angiogram now reveled an 95% blockage in the aretery where 3 stents are. They recommended bypass which was done in October of 09. Both of my doctors were informed several times that I was on prilosec and of course, they continued to prescribe plavix after my bypass until I told both doctors about the problems with prilosec and plavix. The cardio doctor took me off of the plavix but I still take prilosec and he has me on a low dose (81 mg) asprin. I still experience chest pain from time to time but nothing serious. I should look into this class action suit.

i have been taking plavix /prilosec/lipotor/have had many of the same
problems as the other folks including heart attacks leg pains block stent
now i have liver trouble going in for liver bio on monday