Truvada and Other HIV Drug Lawsuits

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Lawsuits allege that side effects of Truvada, Viread, Atripla, Complera and Stribild may have been avoided if the manufacturer had not withheld safer versions of the HIV drugs as part of a scheme to maximize profits.

TDF DRUG LAWSUIT STATUS: Product liability lawyers are reviewing potential HIV drug lawsuits for individuals who have suffered:

  • Kidney Disease, Kidney Failure or Other Renal Injury
  • Bone Fractures
  • Osteoporosis, Osteopenia, Osteomalacia or other Bone Loss Problems



OVERVIEW: A series of HIV treatments have been introduced in recent years, involving the compound tenofovir disoproxil fumarate (TDF), which allowed the medications to be delivered in a pill form, instead of an injection. These treatments included the blockbuster Gilead HIV drugs:

  • Truvada
  • Viread
  • Atripla
  • Complera
  • Stribild

It now appear that Gilead knew that safer version of these HIV drugs could be manufactured and sold, known as tenofovir alafenamide fumarate (TAF). However, the drug maker stopped development of this compound in 2004, continuing to introduce toxic TDF drugs without adequately warning about the potential side effects on the kidneys and bones.

It was not until Gilead was nearing the end of patent protection for TDF drugs, and would soon face competition from generic versions of Truvada, Viread, Atripla, Complera and Stribild, that it resumed development of TAF drugs, which are now marketed as a safer alternative.

TDF DRUG SIDE EFFECTS: Tenofovir is part of a class of antiretrovirals used to treat and prevent HIV, by blocking an enzyme the disease needs to replicate. Sales of the compound were initially limited, since it had to be delivered through an injection. However, this changed in 2001, with the introduction of Viread and other TDF-based drugs, which provide tenofovir in pill form.

Gilead developed an essential monopoly on HIV antiretrovirals, which individuals living with the disease must take to survive, generating over $11 billion in annual sales.

As early as 2001, Gilead knew that side effects of TDF HIV drugs could be highly toxic to kidneys and bones, but inadequate warnings were provided to users and the medical community.

The drug maker also knew about a safer alternative by 2004, but stopped development of TAF drugs, since they would negatively impact the lucrative sales of Truvada, Viread and the other TDF drugs.

According to allegations raised in TDF drug class action lawsuits and individual injury claims, Gilead engaged in a scheme to maximize profits by delaying development of the safe TAF drugs until after they had generated the maximum profits from TDF drugs. When generic versions of the earlier drugs were approaching the market, the manufacturer obtained approval for TAF drugs, which will not face generic equivalents until at least 2032.

In November 2019, the U.S. government filed a lawsuit against Gilead, indicating that Truvada’s use as a prophylactic against HIV was developed using taxpayer funding, and that the company is illegally profiting from that research.

LAWSUITS OVER TDF DRUG TOXICITY: As a result of the drug manufacturers’ failure to adequately ensure the safety of their products or warn about the risks associated with TDF toxicity, HIV drug injury lawyers are evaluating whether users may be entitled to compensation through a product liability lawsuit.

To request a free consultation and claim evaluation to determine whether you, a friend or family member may be entitled to financial compensation through a lawsuit, submit information about a potential kidney or bone loss injury.

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  1. simon Reply

    I am 39 years old, HIV negative and I have been taking Truvada daily for about 8 years as PrEP (pre-exposure prophylaxis). 4 years ago (when i was 35) i was diagnosed with 2 herniated spinal discs and disc degeneration in the lower lumbar spine. As a result i could no longer play sports, exercise, run, bend over, my life was changed forever and the two discs never healed. Chiropractors, Physiotherapists, General Practitioners, all could not understand why at 35, my discs were degenerating so quickly and without healing. Last year (when i was 38) another disc herniated, this time in my mid-thoracic.
    2 months ago I decided to stop Truvada due to my kidney function tests showing reduced function and also due to episodes of pancreatitis i was experiencing – not because of spinal issues (as I had never drawn any link between Truvada and my disc deterioration). It has been 3 months since my use of Truvada and in the last few weeks I have noticed I am now able to bend over with less pain, and i have been jogging for the first time in 4 years. I have not formally followed up with any scans or tests yet, but given nothing else in my routine has changed, I am hypothesizing that my spinal disc degeneration issues are potentially linked to the long term daily truvada usage. I would be very interested to hear from other people experiencing disc degeneration at a young age and potential links to Truvada.

  2. Trygve Reply

    General Dilivery Centralia Was.

  3. Christine Reply

    I took bread from 1993 to 2001 and truvada from 2001 to 2006 and I went into renal failure and began dialysis in 2004 do I have a case?

  4. Jessica Reply

    I became osteoporosis secondary to the drug truvado combivir i suffered a severe pelvis fractue open reduction internal fixation. A year of lost work. I am in therapy because im unbalanced.

  5. Lambert Reply

    I took this medication for over 5 yrs now am leaving without a future because they left my organs devastated.

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