234 results

• Xeljanz Problems Highlighted in Study Data May Lead to New FDA Restrictions: Report

  February 8, 2021

  Irvin Jackson

  The FDA is weighing new restrictions on Xeljanz, following clinical trial data linking the drug to an increased risk of heart problems and cancer, according to a new report.

• Xeljanz Side Effects May Increase Risk of Cancer, Serious Heart Problems: FDA Alert

  February 5, 2021

  Russell Maas

  A new FDA warning indicates Xeljanz side effects may increase the risk of heart problems, including heart attacks, and cancer in patients over 50.

• Aspirin Just As Good As Other Blood Thinners At Preventing Clots Following Hip, Knee Joint Surgery

  February 17, 2020

  Irvin Jackson

  A new study finds that aspirin is just as safe and effective as more powerful blood thinners at preventing life-threatening blood clots following surgery, but is far more cost effective.

• FDA Approves High-Dose, Extended-Release Version of Xeljanz, Despite Blood Clot Risks

  December 20, 2019

  Irvin Jackson

  The FDA has approved higher dose formulations of extended release Xeljanz, despite concerns over the risk of potentially fatal blood clots.

• Blood Clot Problems from Xeljanz Draw Updated EMA Warning for High Risk Patients

  November 5, 2019

  Irvin Jackson

  European regulators warn that Xeljanz should not be given to any patients at high risk of blood clots unless absolutely necessary.

• Pulmonary Embolism Patients Fare Better At High-Volume Hospitals: Study

  August 16, 2019

  Russell Maas

  A new study finds that patients suffering from a pulmonary embolism have a better chance of survival if they go to a busy hospital.

• Zelboraf, Cotellic, Similar Melanoma Drugs May Cause Heart Problems: Study

  August 14, 2019

  Irvin Jackson

  A new study warns that some melanoma drugs used in combination may increase the risk of serious heart problems.

• Xeljanz Black Box Warning Added by FDA, Due to Risk of Blood Clots and Death

  July 26, 2019

  Irvin Jackson

  The FDA is warning that Pfizer's ulcerative colitis drug, Xeljanz, could cause pulmonary embolism and deep vein thrombosis at higher doses.

• IVC Filter Placement Following Traumatic Injury Failed To Reduce Risk of Pulmonary Embolism, Death: Study

  July 16, 2019

  Irvin Jackson

  A new study finds that early placement of IVC filters does not reduce the risk of pulmonary embolism or death in patients who have suffered severe trauma.

• Xeljanz Side Effects at 10mg Dose Lead EMA To Place Restrictions on Use

  May 20, 2019

  Irvin Jackson

  European regulators have placed new restrictions on the use of Xeljanz while they continue to review potential pulmonary embolism risks.