Users of the diabetes drug Avandia face a potential increased risk of serious and potentially fatal injuries. Lawsuits are being investigated throughout the United States for users who suffered a heart attack, stroke, congestive heart failure, bone fractures or death.
STATUS OF AVANDIA LITIGATION: Federal lawsuits have been consolidated in an MDL (Multi-District Litigation) in the Eastern District of Pennsylvania. Cases are also pending in state courts. Although several Avandia settlements have been reached, lawyers are continuing to review new potential Avandia lawsuits.
MANUFACTURER: GlaxoSmithKline, PLC
OVERVIEW: Avandia is a type 2 diabetes medication which is prescribed to help control blood sugar levels. Until 2007, it was one of the best selling medications in the United States, with annual sales in excess of $2 billion.
AVANDIA HEART SIDE EFFECTS: In May 2007, a study was published in the New England Journal of Medicine which indicated that Avandia side effects could increase the risk of a heart attack by 43% and the risk of cardiovascular death by as much as 64%. The study reviewed data from over 42 different clinical trials, involving over 28,000 diabetics.
The FDA has added a “black box” warning about the Avandia heart attack risk, as well as about the risk of congestive heart failure. Experts have suggested that as many as 100,000 heart attacks could have been caused by side effects of Avandia.
AVANDIA BONE FRACTURES: The long term use of Avandia has also been associated with an increased risk of osteoporosis and broken bones. Avandia side effects could increase bone resorption and decrease bone formation, potentially leading to weak and brittle bones that may be prone to fractures and breaks.
AVANDIA MACULAR EDEMA: In December 2006, Health Canada issued a warning that indicated that Avandia could lead to new cases or worsening of a vision problem known as macular edema. This is an inflammation of the retina caused by accumulation of fluid behind the eye, which results in blurred vision, decreased color sensitivity and poorer adaption to darkness.
AVANDIA LAWSUIT SETTLEMENTS: GlaxoSmithKline has agreed to pay millions of dollars in compensation to former users of their diabetes drug who suffered heart attacks and other problems.
Potential cases are continuing to be investigated by Avandia lawyers throughout the United States for users who have suffered from:
- Heart Attacks
- Congestive Heart Failure
- Bone Fractures
- Vision Loss, Blindness or Macular Edema