A draft guidance seeks to require broader clinical trials for diabetes drugs, in an effort to better identify potential adverse health effects before they receive FDA approval.
A new study indicates diabetes drugs like Avandia may cause heart problems through mitochondrial toxicity, which could be preventable through the use of other medications.
An Actos lawsuit, filed years after many cases were settled, blames the diabetes drug for a man's bladder cancer and eventual death.
The FDA has updated Actos label warnings with additional study information and reinforced its belief that the diabetes drug's side effects may increase the risk of bladder cancer.
The findings of a new study suggest that there is little difference between a variety of diabetes drugs currently on the market, despite a wide range of risks.
A new study has found that the use of Actos increases the risk of bladder cancer by 63%, and that the risks appear to be specific to that drug.
Researchers warn that while Actos may prevent diabetes in some cases, users face an increased risk of bone fractures, weight gain and edema.
An undisclosed settlement ends an Actos bladder cancer trial that has been ongoing since late August and follows a larger settlement agreement affecting thousands of cases.
A $2.4 billion Actos settlement can go forward now that enough plaintiffs have agreed to participate, the manufacturer has announced.
A new Actos trial is under way in Las Vegas, over claims that warnings were withheld about the risk of bladder cancer.
