FDA Panel to Evaluate Side Effects of Restylane, Juvederm and Other Dermal Fillers

A panel of outside advisers to the FDA will meet this week to review reports of dermal filler side effects, and to consider whether the regulatory agency should place new warnings or instructions on the injections used to reduce wrinkles and scarring.

According to an FDA document posted Friday on the agency’s website, there have been 930 reports of dermal filler side effects received between 2003 and September 20, 2008. Some of the problems were associated with administration of the injections by untrained professionals or in a setting other than a doctor’s office.

Although no specific products were identified by the FDA, the more popular dermal fillers available include Restylane and Perlane from Medicis, Juvederm from Allergan Inc. and Radiesse from Bioform Medical.

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Dermal fillers, which are also known as wrinkle fillers, are injections given to smooth wrinkles for a younger look or to reduce the appearance of scarring. According to the American Society for Aesthetic Plastic Surgery, about 84,000 men and 1.36 million women received a wrinkle filler injection in 2007.

The FDA advisory panel is scheduled to meet tomorrow in Washington, D.C. to review the safety of these products and whether any regulatory actions, such as strengthened warnings or additional instructions, may be necessary to protect the public.

The FDA review indicates that some people given dermal fillers suffered “serious and unexpected” side effects, such as facial palsy, disfigurement and rare life-threatening allergic reactions or anaphylactic shock. In some cases, surgical procedures have been required to treat these problems, such as draining abscesses.

Other wrinkle filler side effects have included inflammation, pain at the injection site, numbness, bleeding, blistering, bruising, migration, formation of lumps or nodules and infection. Minor problems, such as a small amount of swelling or redness, are known and expected side effects and are currently described in the product literature.

The FDA is attempting to determine whether additional studies are necessary and whether any updates should be made to the product labeling. Although the FDA is no required to follow the recommendations of their advisory committees, they often do.


248 Comments


Ruth
I had Sculptra injected over a year ago. Not only is my face distorted, but I get daily inflammation, swelling, burning and redness. I look like a freak. Dual board certified doc never bothered to tell me of all the risks or the fact that it was irreversible. This crap cost me my health, my job, my confidence and my emotional well being. Please, please, please stay away from this poison.

Jersey Girl
I had pitted scars from acne on one cheek, and was very self conscious about them. I went to a well regarded plastic surgeon with experience in injectibles. He injected the pitted areas with Juvederm. I didn’t realize this was an off label use; he’s the doctor and should have informed me. Or I should have done more research. I noticed lumps in my cheek within a month and went back to the doctor. He offered to inject the area with hyluronic acid to dissolve the Juverderm. Stupid me! I said no because I had paid so much for the injection, and thought it would dissolve on its own! Now, 6 years later, I have permanent raised lumps in that area that have not disappeared. I had the hyaluronic acid injected a year later by another doctor, but at that time it was too late. Nothing dissolved. I had gone back to the first doctor after a year to complain about the lumps again. He thought that the underlying acne scarring prevented the Juvederm from correctly filling in the underlying area. Why couldn’t be have thought that could have been an issue before the injections? He suggested a face lift to smooth the area..as if! I had also called Allergan to complain..the woman on the phone said they had never heard of any reaction like mine..oh, please! Utter bull.

Lisette
I am adding to an earlier comment Feb 25th. I was encouraged to do a biopsy to rule out sarcoidosis. I think he injected me in my lymph glands. I called the doctor and told him that and he said it was ridiculous. The ER doc said that when a substance enters the lymph glands which are mostly under eyes, exactly where he injected me. The white blood cells,(the soldier cells) eat the substance even though it is water soluble and try to desolve it and cannot. So they move from one area to another virtually a life time. I talked to a doctor in costa rica and he mentioned a medication that is good with granulomas. He said it is called “Accolatae” he has had good results with it. It was initially as a medication for asthma . He has had good results with it. HAS ANYONE OUT THERE HEARD OR TRIED THIS MEDICATION??? please write back. Thanks

Tory
I am basically having most symptoms of Sarcoidosis and immune respons to include lungs, skin, endocrine, muscular, skeletal – almost all of my body systems seem to be affected by this? Look up Sarcoidosis and see if it isn’t similar. :-/ It’s an autoimmune disease.

Jen
I also have been having problems with blood sugar (reactive hypoycemia) since the fills – i am wondering if I may have autoimmune Sarcoidosis. have no appetite and hard to eat from nausea which happened immediately when product was injected each of the 3 separate time.

Jen
I also just learned of enlarged lymph nodes in my lungs after flu-like symptoms. It triggered my asthma badly. Fatigue, loss of appetite, nausea, body aches, headaches….I am now on Prednisone, steroid inhalers and albuterol. My lungs are painful and I have shortness of breath. Labs so far are normal except for the lymph node.

Michele
At 58 years old, I seemed to have developed cystic acne and hair folliculitis along my hair line. I have had both botox and collagen injections, but none for over a year. These injections were performed by a dermatologist, and she along with 4 other dermatologist have emphatically told me, the acne nor the folliculitis are from the injections. Still, I could not understand , why at this time of my life, would I develope cystic acne. After searching the web endlessly for over 6 months, I stumbled across this site. Has anyone else experienced similar symptoms from these injections? TY

tracie
I was injected with non-FDA products (medical grade silicone or Aquamid) against my knowledge in a non-invasive beauty makeover…I sent many biopsies to the Dept of Health and called in the FDA, and was put in a fraudulent contract, seeking Declatory relief and the guy just died, and I am free to talk. I need to hear from a good atty to go after his estate,as I have been permanently damaged and am currently working with a well know Plastic surgeon making break throughs on how to manipulate the product from the outside before surgeries, lots to tell, need to speak with one of your Atty’s and asap. Thank you Tracie Miami 🙁 HELP!!

Jen
Juvederm Ultra has lasted 3.5 years around the corners of my mouth leaving lumps and drapey skin. Nothing will dissolve this – I’ve tried it twice. We were majorly misled about this product being temorary or dissolvable.

Lisette
I had jevederm injected a year and a half ago under my eyes. I didn’t think I needed this and had a promotional coupon and asked the doctor if he could save it for when I needed it around my lips. He said no we need to use it, I think you can use some under your eyes. My cheeks turned red and I had a bluing under one eye. He said it is called tinsel effect and would go away. I looked like a chipmunk and went back to him telling him one side was bigger than the other and he said it was not that noticeable and I am being “too microscopic”. Nine months after the injection I noticed a lump between my eyes growing and thought it was a pimple. Then I noticed multiple lumps. Went to my doctor and had a needle nose aspiration. The report said, “silicone like substance” and only surgery would help and would be left with a scar. I called the surgeon after the cheek area started getting lumps. He injected me with cortisone and it seemed to help for about 4 months. The lumps are back on the forehead and when I went in to see him again he said, I never injected you in that area I had no choice but to go home feeling frustrated. A week later the lumps on my cheeks came back and I did research and realized that the lumps migrate and even though he didn’t inject the area between the forehead, they migrated from the cheekbones because I have never had any injections between my forehead. What should I do? If he cannot make this right then I am going to sue him.

Chantelle
I am wondering if anyone remembers Radiesse issuing a release several years back about granulomas? Apparently the product was more prone to granulomas before being reformulated, this happened in 2010 or 2011. Please reply if you have information on this.

Sherry
I have had Restylane injections in my lower face and they have worked well. I was considering getting my temple area done. I will never get any hyaluronic filler put in my face near my forehead area now. It should not be legal for a doctor to inject this area. The risk is too great. All I can say is that I feel so badly for all of you that have had to suffer from these money grubbing doctors that don’t care about the risks, they only care about the money. Thank you so much for sharing what has happened and warning people by posting this. I pray that you all get better.

Henriette
I had restylane from a certityed professional around my mouth and nose and in the forehead in july 2012 here in Denmark. 3 weeks later i started to develop Subacute thyroiditis. Inflamation of the thyroid gland. I am still suffering this, and as a chemist I have read a number of articles on this subject (dermal fillers and sideffects) and it is very very likely that granulomas that reslylane couses can lead to this desease among other very nasty ones. I have been ill for 6 month wich has been awfull. I want to say to everyone: Stay away from these fillers, as they DO harm your body.

Average Guy
45yo male i havent had anything go so wrong as some people here but just wanted to share my experience. like many here, was going away on vacation wanted to do something to look a little younger. so instead of a haircut and color like most people would do, on a whim i went and got a juvederm “consult”. she ended up talking me into filling my nasolabial folds. i told her i was off on a cruise in one week and asked several times whether i would be good to go by then. “oh yeah” she said assuredly. “How long have you been doing this?” i asked. “Over 17 years, you’re not my first patient” she replied. I detected a sarcastic tone. hmm. anyways…ok. get the injections (which were more painful than i expected), paid them over $600 and went on my merry way. 5 days later here i am… the left side of my face looks like i got punched. it’s swollen and bruised and frankly it looks ridiculous. only on one side mind you. the other side looks fine. and i can feel the juvederm under my skin, a hard “tube” of it…feels like someone cut a sharpie marker in half and slid it under my skin. Concerned, I went back to the same place today and asked …”Why?” “Oh nothing to worry about” she says”it’s swollen and once the swelling disappears you’ll love it”. Uh huh. So …flying out tomorrow to Miami …gonna feel like everyone is staring at me because it looks like a was just in a fight. Paranoid or not, it doesn’t look “good” by any stretch. With all the hype surrounding injectables, like they’re a “lunchtime lift” and back off to work you go, one might think that would at least fall into the category of false advertising . I’m sure juvederm works just fine for many people, but if you think there’s no swelling or bruising or lumps and bumps, you’re in for a surprise. Hopefully the “tube” of juvederm softens and flattens out or even after the swelling does go down, it’ll look like a pen under the skin in my nasolabial fold. I’ll have to go back and get it dissolved, probably for a fee, and there i’ll be out 6/7/$800? and won’t have anything to show for it. Nice. Kinda feel like like a sucker. but i don’t think you can sue for that. Too bad. If you’re considering fillers, read through this page first, then decide. I wish I had.

Annabel
I had Juvederm injected into my tear troughs 8 months ago. It’s still lumpy and awful and blue. I look older and weird. I’m embarrassed to leave the house and have almost completely stopped socialising. I saw a specialist reconstructive surgeon last week who said to give it another year, and to definately avoid dissolving injections. I’ve written a letter to the company who did this to me “Transform Medical Group UK” asking for compensation and threatening legal action. My eyes are puffy and blurry, I’m no longer attractive and im now on anti depressants due to this. I’ve lost my fiance and all my confidence. These liars and thieves need to be stopped from doing this. Prayers to all of you

cindi
Hi, I m an RN, I started injecting myself about 3yrs ago, I used restylane at first and had good results, I had the usual bruising and swelling. I then tried a cheaper brand of hyluronic acid called Juveni, it was very painful, swelling was terrible and it didn’t last. i have since gone for training and have used juvaderm latley with very good results. I suspect that some physicians use cheaper brands and are not trained and don’t practice at all don’t tbefore they start injecting for big bucks. I have had a couple of bad experiences with board cert plastic surgeons. That is what encouraged me to learn to do it myself, now that I have gone for training, I plan to open a med spa offering fillers. I will be using only ,hyaluronic acid, I don’t trust Radiesse or sculptra. I had a bad reaction to Radiesse, and have read about many problems

toby
I had Radiesse under my eyes for hollowness. Do NOT do it! It’s not FDA approved for under eye area and ps knew it but did not tell me until things went horribly wrong. I still have bags under my bags. PS told me that the company said that it destroyed my lymphatic system and that’s why the swelling won’t go away. I had redness for months as well. The swelling was so bad that the first year I wore sunglasses everywhere I went day and night. I got 2nd opinion and that ps told me the 1st ps didn’t inject deep enough but she claims she did. I hate looking in the mirror to this day. It’s ruined my life. I used to look in my mid 30’s and now my eyes look like I’m in my 70’s or 80’sand I just turned 50. Good Luck finding anyone or anything to help. I’ve spent hundreds on creams and even had laser treatment with no results.

DIAN AADC
Dear all, Thank you for sharing your experiences…i’m thinking of doing some injections to my cheeks and nasolabial folds…I even set my appointment with dermatologist already…i’m a 31 years old with saggy face …reading all your stories make me think that I really need to reconsider my intention to get the injections done…my thoughts and prayer are all with you….for those having side effects from dermal filler/botox , I pray for your speedy recovery…thanx again……..

Gus
I am a 37 year old male, approximately 5 years ago i did the mistake of having 6 injections on my forehead with the objective of minimizing wrinkle lines. approximately 10 months later visible red lumps appeared in the exact places where the injections where done, some larger then others. I am not sure what the product that I had done is, as the place where i got them done is no longer active. Looking at this page i can see I share some of the unfortunate tales, my bumps are part of my daily life they are on my forehead and noticeable,, makes my life challenging, as i try not to focus on them, i hate it when people ask me what happen to my forehead, i try not 2 fall in depression, has been approximate 5 years now, is clear they are not going away, my objective on sharing my unfortunate incident with you is that i am urgently seeking to find a doctor or dermatologist that has experience dealing with such cases that can actually help me, I reside in mexico however willing to go anywhere where I can find a specialist in this field. Please if some one has had a similar experience to mine and corrected or minimized the lumps, point me to the doctor if you have similar situation to mine i be more then happy to share your pain. as i know what you are going through. thank you for your attention.

Erika
.I did my restylane injections for three and a half years ago in Sweden. They said that this was completely biodegradable and it would be no residues. Now the big famous plastic surgeons in Sweden go out with this filler may be permanent. It was not what I paid for. Why not investigate restylane more, let someone chemist break down the material and make analyzes. I suspect that there are permanent products in it. It can lead to major charges against the manufacturer that markets the product as non-permanent.

Debra
My first reaction to all I have been reading…you guys have let your healthcare professionals inject you off label. Restylane and juvederm are FDA approved for nasolabial folds and marionette lines only. You must research and be an advocate for yourself before you have any of these injections done. Please remember to go to a dermatologist or plastic surgeon. I have heard any type of Dr. Can go to a one day seminar and do these injections. They then can let nurses in their practice do the injections. Not a smart move to trust these people. Never use a product off label…never trust a healthcare provider that will use it off label. I am so sorry this has happened to all of you 🙁

Mary
Hi there I just wanted to give an update on my hellish experience with the dreaded juvederm,its been 17 months now and I’m still in the thick of this burning dementia fog as I call it.I have now vision loss in my right eye,enough to warrant the need for prescription glasses.Hearing loss in the left ear,accompanied by 24 high pitched tinnitus.Severe memory loss,with cognitive decline.Permanent burning in eyes,forehead and inside head,feelings of suffocation,squashing,nausea,dizziness,muscle wasting and fatigue.My brain literally feels like acid is burning holes inside it,I have slowed reactions,fall over,misplace things,my body aches as if I run 20 miles a day.Im 42 soon and feel 82,I had these injections at 40 years old,people would tell me I looked 30,now I look 50.Thus is sick,it’s cost me so far almost £12000 to try and get better,my marriage almost ended,im having to relocate my family and have lost friends because they can handle me being sick for so long as I can’t socialise like I use to.This stuff is toxic bio hazard material,my hair is still coming out in clumps,how dare these pharmaceutical companies advertise this as safe and natural,it’s bloody made from strepptococcus bacteria and polymers,binding agents,God only knows he long term effects of this.I pray for everyone suffering,that you get better,no one deserves this,it’s torture.Does someone have to die before the government sits up and takes note of all the side effects of this and how sick people are getting.The list on here is getting longer,and will continue too,I hope whoever is going to sue Allergan doesn’t take too long,all the best.

eva
I had Juvederm in my cheeks and upper lip six months ago by a nurse in England. It made me look deformed and I immediately wanted to get rid of it but the nurse told me I couldn’t. Since then I have had swelling, pain and looked like a chipmunk. I finally had it dissolved with Hyaluronidase but still have pain in my cheeks and not all of the product has gone. Juvederm should be banned. It is completely unsafe, more and more people are reporting problems. I wish I had never gone near this clinic as they appear to be only interested in taking the money and persuading people to have totally unnecessary procedures. Juvederm, in some people appear to affect the nervous system and cause severe adverse reactions.

chad
would also like to add… I was thinking about getting it disolved but from the comments above looks like that only makes it worse, so I will wait it out to see if my body can overcome this disease naturally. Juvedisease is what it should be called. there is nothing rejuvenating about it, unles you consider looking like gollum healthy. Everyone please post progress reports, or sadly regress reports too.

Chad
I had a juvederm injection above my right eyebrow around 6 months ago to fill in a scar and it has been the worst decision of my life. I original asked about getting laser treatment to smooth the scar but somehow I was talked into having this junk injected into me (harmles, will disolve, you wont even notice it’s there, blah blah blah) which all turned out to be lies.. six months later, I still have a noticeable lump and it pushed my eyebrow down, so i now have asymmetric eyes. My hair is falling out of my head and eyebrow(right side, left not as bad).. I know its from the juvederm because I had really thick dark eyebrows and a thick head of hair. It is now really thin and getting worse every day! it just keeps getting thinner, I’m afraid it will be completely gone in a couple more months. I have a strange dizzy feeling not like anything I’ve ever felt(not like low blood preassure, or head rushes), headaches (right side only) and I can’t think clearly. I also have crazy dandruff which I’ve never had which is clearly from my body trying to get this shit out of me. Has anyone gone through the hair loss and had it grow back, or am I permanently fucked?? how much longer do i have to go through this hell? I only had 1/2 a unit of juvederm. I feel for you people that are going through serious health problems, I can only imagine how bad that must be.. I don’t think i’ve even had a bad/allergic reaction to it, it’s just really bad for you… natural my ass! It’s def toxic and my body is fighting tooth and nail to get rid of it.. which reminds me, my nails are very brittle too and break off with ease. this stuff should not be legal! it’s amazing to me that it is. I wonder how much the FDA was paid to approve this garbage.

Aviva
Thanks for sharing your stories. After reading them I will never have any substance shot into my skin. I try to remember what a doctor told me years ago,”We are practicing medicine.”

eve
Hi Agnetha, I had Juvederm in my cheeks, since then I have been having these symptoms of breathlessness and my face looks worse by the day. Now i am developing blue marking and sagging under my eyes. This product should be banned – it is far from safe as the manufacturers wish us to believe.

Syndy
So glad I found this website..I too had Juvaderm Ultra injected 3 years ago by a Board Certified well respected Doctor and it’s been a nightmare ever since..I was swollen immediately..knew something was wrong and had it dissolved a little and it still looked awful..from what I’ve read Juvaderm should not be placed in the tear troughs. I’ve been to an allergy specialist, ENT Dr., Dermo and no one can tell me what this redness and bumps are caused by and how to get rid of it. Had more dissolved recently only to have a blue vein appear out of nowhere and a dent in my face. Was told by my P.S. To go to my Dermo and get what’s called a V Beam laser. Had that procedure and woke up for 2 weeks with my eyes completely swollen and still red with bumps..a friend dragged me to a registered nurse who does injections and IPL lasers all day long and I think I’m finally seeing light at the end of the tunnel..With only one treatment of the laser the bumps have decreased and the redness is a little lighter. With make up it’s even better..not only do I think the Doctors are responsible but the manufactures should be held accountable..Called Allergan today and spoke to a girl who was basically useless and very unprofessional and lacked the knowledge of the product that employs her. They take a report period..she doesn’t know what happens next and doesn’t have a manager to speak with or any more information. If there is some kind of class action suit against the makers of this product, I would love to be included..

agnetha
Started using restylane and botox for about seven years ago. Cosmetically sucessful!! Lips look good and fuller with restylane. Wrinkles between brows gone and my eyebrows lifted by making my eyes less tired. BUT however, this will bew my last treatment!! My headaches are getting more severe after each treatment. Muscles pain like symtom of flu, plus weakness, pain in my body and chronically tired and not to talk about problems with swollow difficulties and chest tightness, waking up in the middle of the night chipping for air..really scary!! And im a very healthy person. working out everyday, eating healthy, neither smoke or drink.. But my body pain like influensa, loosing energy is now impending me from working out that often!!! Does anyone have this problem…I feel soo foolish by letting my vanity damaging my health!! I know is due to restylane and botox!!! I have 2 sisters neither of them have try restylane nor botox…My sisters do not have these symtoms!!! Need to know if I ever get rid of these negative side effects!! Will never use Botox, restylane or any other substance again!! Rather grow old gracefully than losing my health Agnetha

helen
I have been thinking about juvederm lately and having read all your experiences I now realise the dangers are just to great. Thank you for sharing and helping others to know about the very real and scary risks. I know it may not be of any value to read this considering the nightmares some of you are going through but I really want to say courage and strength be with you and my heart is just aching for what you are experiencing. Our insecurities about how we “look” are fueled by a society that creates products that we find out we cannot trust (all in the name of dollars). It is so so tragic and sad…

sandy
On sept. 26 I had juvederm injected to nasolabial folds. On 9-27 I had quite a bit of swelling on the left side and the left side of the inside of my mouth was burning quite a bit. By 9-27 I had 2 horizontal cuts on the inside of my mouth and a few open sores. I called the softer on 9-27 and she ordered valacyclovir 2 doses. No improvement. I saw her on 10-1 and she ordered 7 days of the same med. the burning and open area in my mouth are horrendous. The bruising and redness on my face is horrible extending to my chin. I would not recommend juvederm to anyone ever. I also have excoriated area at the creases at my left nose. I don’t know if I am going to call and see her again or try my fmd! When I saw her on 10-1 she basically just smiled and said this happens sometimes. I wish I would have found this site before!

Pattie
On Sept 10 2011 I was injected under my right lower eye with Restylane, This was the first injection the doctor made on my face. After he used the words I like to go deep under the skin he injected Restylane and severed a blood vessel under my eye. He went about injecting into different places on my face never mentioning what had happened after the first injection. My best friend who happens to be a doctor was in the room with me waiting for her turn. She noticed an instant port wine stain growing on my nose and along the right side of my face. She mentioned this to the doctor who said oh yes some bruising occurred. Nothing to worry about bruising happens. After her treatment she asked again why was my face having a bluish growing bruise on it. This doctor never said that he severed a vein in my face and that I needed emergency medical treatment to save my face from necrosis. The reason he did not say I needed help was because he was clueless as to what he had done to my face. He did not know that what he had done required immediate medical attention.He did not have the proper training to be giving injections because if he did he would have known that I need treatment ASAP. He let me go home without proper medical care. We took an elevator down and by the time I got to the first floor my face was shooting blood from the injection site, We went back up to his office very worried over my bleeding face. He took a look at the bleeding site and said oh just blood from bruising no problem now you won’t bruise as much. I went home trying not to freaked out. My face was getting worse by the minute. I returned to his office three different times asking him to help me my face was in terrible pain and white patches where showing up. Each time I went he acted like everything was great. His advise to me was relax it was nothing more then bruising and it would be gone in a couple of weeks. I had the procedure done on a Saturday on the following Wednesday my husband returned from a trip out East. He took one look at me and called a specialist to see me on an emergency basis. By this time I thought I had flesh eating disease. The white patches had turned black and puss was coming out of them. I wiped the area and found open holes in my face where once beautiful healthy skin was. I was examined by a doctor who told me what had happened. That upon the first injection the doctor hit a vein and severed it in half. He continued to fill the area with Restylane He advised me that when this happens there is an emergency procedure to reverse the side effects and it needs to be done ASAP. He said I was not given the proper medical treatment I needed so there was little he could do because the damage was already done.. At this point all he could offer was burn cream. He said he would not know for many months just how badly scared I would be. I used the cream day and night. I was unable to attend my family reunion, my class reunion and my daughters last high school home coming. I missed three planed vacations with my family. I was holed up in my house for 6 months only to go out to see my doctor weekly. In June 2012 saw a Laser Specialist who works on facial scars. It is now Sept 15 2012 and I am still receiving Laser treatments to help heal the scar left from my Restylane injection. I went to see the doctor who did this to my face after seeing a specialist. When I saw him he said to me “What no smile from you” and next he had the nerve to ask me “What do I think happened to my face” ….. he was not kidding…He was asking me..Who is the doctor here me or him. I have hundreds of pictures of this nightmare.What I want more then anything to let other women know that what happened to me can happen to them. Anyone who allows a doctor to touch their face must ask them if they know the emergency procedure to reverse the effects of an severed artery should they hit one. I only wish someone would have warned me.

Pam
I had sculptura injection 6 years ago which left a small bump under the skin which has now turned into carcinoma. Sculptura is likely the cause as I always wear sunblock and large hats. Scarey!

Simone
Reading these comments is just soo distressing. I wish all of you some respite from this horror. I am 41 and hate the 11 lines between my eyes. I had pretty much decided to have a combination of “temporary” dermafills and Botox, thinking that administered by a PC it would be safe. I like you seemed to be under the illusion that any adverse side affects from temporary fillers would be minimal and temporary. Having read about your experiences I have decided that there is no way that I would risk this. Thank you for posting this, my thoughts are with you.

Mary
I had juvederm injections a month and a half ago I have experienced many problems, including illness, I am 46 but if you look at my upper lip from my nose down to the bottom of my chin I look 30 years older, from the nose up I look my age if not younger, I do not know who I am in the mirror, I am devastated. I do hope someone will do a class action in regards to what has happened to so many of us.

Joanne
I had Juvederm injected six months ago just before going on my vacation to Mexico. It has been a nightmare of swelling and lumps ever since. At first it was thought that I had an infection so before going away I was put on antibiotics. This did not help. Stayed swollen and could not have any pictures of myself taken. I looked like a goul. When I came back I went to my plastic surgeon (he did not do injecting). His injector gave me several shots of hyaluronidase on the right side of my face. This worked for a time. Swelling began again. For several weeks (just recently) I could not open my mouth because my jaw was so sore. Well, another nodule has now migrated out of my jaw and is sitting on my cheek. A couple of weeks ago I arose in the morning to see a person I did not recognize. The whole of the left side of my face is now swollen up. A test was done to see if this area was infected. It was not. I had hyaluronidase injected again on the left side. As of today and six months after the injection I am so swollen I could just die. My face is burning and it is red. Will have to go tomorrow and get something done. The only thing that I can say about this whole experience is that I have a wonderful surgeon who is very concerned about all of this. They have discontinued using Juvederm. He is doing everything possible to help me and he also refunded all of the money I spent. I have a feeling though, this is going to take quite some time before this JUNK – Juvederm is out of my face. If it ever comes out. Allergen who make this stuff said that they have never heard of any reactions like mine. Such liers. This filler should be banned as it is highly dangerous as you can judge from the above comments. I pray for all of you girls and myself as well. I hope that we all can overcome this stuff called “JUVEDERM”. If any doctors are reading this, do the responsible thing and get it banned from use. Also help your patients. This is like having a disease that keeps growing and growning. I do not know where the Juvederm is coming from. I have had so many shots to dissolve it. Prayers to everyone.

Marene
I had Perlane injections for my nasal folds. I thought I was happy with the results. However, I noticed lumps on the right side of my fold near nose and lips. Also the “volume” around the areas in question have flattened. I asked the doctor’s office about that and I was advised to wait a while. They thought it was swelling which was normal. Lumps or nodule-like bumps have not gone away. I went back for an appointment and their nurse massaged my lumps. It seemed to work. I got home and saw a lump. It bothered me and I asked doctor about it. I went back for another injection for a reduced price. I did not notice lump till a friend took a picture of me and posted on his Facebook. I saw the lump on my right fold and it was embarrassing. I checked and felt the lump. I tried to massage it and it seemed to migrate around the area. My concern is that the lump might be permanent.

Anne
I had several Restylane injections in my lips and nasal folds from 2004 – 2007. Botox two or three times in the crows feet area. Came down with debilitating Multiple Chemical Sensitivity, became disabled. Was healthy and in great shape before. Research doctors who deal with MCS told me that both Botox and Restylane are neurotoxins and can cause this horrible disease. Now I cannot tolerate fragrances, fabric softener, anything scented, most drugs, the list is endless. Cannot travel or work. For what? To look a little younger for a few years?! The pay off was asthma, respiratory problems, and the life of a hermit.

karen
I had Juvederm done on my forehead Dec 1st 2011. I left with loads of broken capillaries and lumps and since then have had lots psoriasis like hives mainly on my face and some on the body ,extreme dizzyness,heavy feeling in my forehead and in Feb 2012 my forehead swelled like a balloon for several days and only started to subside after taking some allergy meds .I contacted the clinic as I believe it was done incorrectly and it is advised to not have forehead done as it’s dangerous and was never told this .I wanted a refund ,after many calls from them saying no to a refund but they will retreat which is a firm NO on my part ,they now have come back and said I never had Juverderm done and hung up on me ,this is a Toronto based clinic that has many clinics. There needs to be stricter guidelines with this product as it’s causing much distress and health problems to many !!!!I have contacted Allergan to start taking this further and waiting on them to conduct a safety report !

Pamela
I too had Juviderm injections on the cheek bone area. I too have a blister–water like–which formed under one eye. A very experienced nurse performed the injections. I have had Juviderm and Radiesse injected before with no problems. In fact, both of these products did not last a long time. . .less than a year. I am hoping the swelling in my eye subsides though after reading this site I hold out little hope. I received the injections a week ago. Will give it more time before thinking of using the enzyme to dissolve same.

Sherry
I have had restylane under my eyes lasting 3 years this summer (2012). It was injected too superficially, according to my new doctor and everone else who knows about results similar to mine. I would like a cheek lift to smooth out the results of the restylane, but the doctor said the restylane must first dissolve. He wants to use Vitrase injection to “melt” the restylane. The doctor says I have festoons from the improperly injected restylane. Also there are two irregular lumps within the injected area that look similar to blisters. Also below the injected areas are one-inch dark lines (shadows?) that form a separation between my lower eyelids and my cheeks. In other words, it does not look smooth from my cheek up to my lower eyelash area. I know I need the cheeklift due to aging alone, even if I did not have the restylane, but the need is now worse, with those dark lines on both sides of my face. Beware, get a doctor very experienced with injectible fillers and in fact with any procedure you’re considering. Be sure the doctor is experienced with the specific area of the body, For example: restylane in lower eyelids. Restylane can last INDEFINITELY, mine is.

Patrice
I had Restylane in my lips & around my mouth on a cruise 2 weeks ago-I was & still lumpy but friends (who didn’t know I had it done) said “boy did that vacation do you good, you look great” I did look up Restylane and it did day it could take a few weeks for the lump/bruising/swelling to go down. a little while ago I looked into the mirror & my lips are purple looking and it looks like I have purple lip liner around my lips. I just called the doctor & left a message. I am FREAKING OUT after just reading all the heart & nerve problems people are having. If anyone knows anything about this, please re-post to me or email Thanks

Cindy
I had Radiesse injected in my nasol folds and in my chin on Dec 21, 2011. My face was distorted did not look like myself for a while and my face becomes super red and like a burning sensation. The Radiesse that was injected in my chin moved and I now have a white lump in my gum line and on the inside of my lower lip. I went back to the doctor because I am concerned. She tried to tell me it is a canker sore 🙁 and gave me some steroid dental paste. I was changed for what should have been a follow up because I developed complications. I got a bill the other day in the mail for the office visit. I have gotten sinus infections about every 6 weeks as well. This product should be taken off the market in my opinion. I don’t know if this doctor just does not know what she is doing when she injected this filler in my chin. This stuff is super expensive as it is. I highly advise people not to get it. My face turns super red and is flushed since getting radiesse.

Diane
I had 2 syringes of Juvederm Ultra Plus injected on my nasal labia folds. Right after the 3rd of 4th injection I started to feel a numbness in my head and pressure along the temple area. Also had a strange “taste” in the back of my throat and a slight tightness in my chest. The dermatologist thought I was having a Panic attack, or a reaction to the Lidocaine in the Juverderm, but I have experieced anxiety before and this was different. Stayed in her office unitl I felt well enough to drive home. It took about 48 hours for this ill feeling to subside. However, the filler has made the lines in my face much softer and not so noticeable, The dermatologist wanted me to come back to finish some lines in the jowel area. She said she would try Radiesse instead of the Juverderm. But, not sure I want to take this any further.

mary
It has been almost two days since juvederm was injected to add fullness to my jaw line. The bruising is still very ugly and camoflage doesn’t conceal it. I also have fine lines that were not there before.,

allison
I had a terrible reaction from juvederm and now i have multiple chemical sensitivities. I read on here another woman has exactly what i have now, I was very healthy before. Does anyone know of any lawsuits or class action suits?

Mary
I agree totally Kyla with that comment i am so ill now that even though i had pet scan it doesnt show exactly what the problem is.I had and still have all the symptoms you have expressed.I am having theses burning symptoms all the time my eyesight is getting worse no doctor can help i am trying to get a biopsy but noone will do it i am slowly dying from this toxic stuff i am not the same person anymore i cannot leave the house hardly the burning is just wont stop all because i didnt want botox i was never warned of these possible side effects who will believe these symptoms,who even cares people say its our fault for doing it in the first place i am so scared i dont know what to do i need help and no one is listening i have been told im mad that im imagining this all how can you imagine this.Its disgusting this stuff is allowed to damage people.I havent been the same for 6 months now my life has gone i was so healthy.What can i do.Someone please help.

Kyla
I have had a serious life threatening condition that I believe was caused by Juvederm injections. I received injections in my lips and cheeks on three occasions (Vancouver B.C.) and although they were done by an experienced plastic surgeon and looked great, I noticed some minor side effects with the first two injections such as soreness at all areas injected that never did go away and a nerve related issue around my mouth that did eventually resolve and was brushed off as not serious by the surgeon. I was also getting headaches on a regular basis which I usually get only very rarely and did not at that time think they were related to Juvederm. However, after my last injection I became very ill. By the day after my injection, I had become very lightheaded and dizzy. That symptom worsened and I also started getting other symptoms such as weakness and numbness in arms and legs, some very serious heart issues, constant muscle twitching throughout my body, eye symptoms (eg flashes of bright light even when my eyes were shut). Within a few days I went from being a strong, fit personal trainer to being unable to stand because of the lightheadedness and fatigue, or even leave my house. I started having anxiety attacks which I had never had before. My body felt so sick and weak, I didn’t think I would recover. I saw many specialists including a cardiologist, neurologist, internist and nobody was able to find what was causing my illness. I eventually did mostly recover but it took about a year and a half before I could even start working again. I strongly believe it was the Juvederm injections that caused this serious reaction and have noticed other stories of similar serious neurological and cardiac issues on this forum although there are no warnings given anywhere of the possibility of this type of life threatening reaction. If anyone has any helpful information in relation to this or knows of a class action lawsuit in relation to this please post info.

mary
I am now going blind from juvederm in glabella and have brain damage from the juvederm migrating into my brain confirmed on pet scan i have lost 4 and a half stone my hair is falling out and i have severe toxic brain ebcephalopathy.My brain is no longer functioning and i cannot even walk up a flight of stairs.The hyaluronidase administered 6 weeks after the juvederm has caused severe burning 24 hours a day ion brain forehead and eyes i do not sleep eat or even go to the toilet anymore i am dying and it is all to juvederm god help me.Mary

Li
I LOVE MY Restylane injections!! It has changed my life for the better.. I am sad to see these people with problems, I did LOTS of research and checkedc alot of DRs.

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