Sports Betting Addiction Lawsuit Sports betting addiction lawsuits are being investigated for college students and young adults who developed gambling problems after using apps like FanDuel and DraftKings, alleging that the platforms failed to warn about the addictive nature of their features and marketing practices.
Nitrous Oxide Lawsuit Individuals who suffered harm, or families who lost a loved one after using nitrous oxide products may be eligible for financial compensation through a nitrous oxide lawsuit.
Hair Relaxer Lawsuit Regular exposure to chemicals in hair relaxer may cause uterine cancer, ovarian cancer and other injuries. Women diagnosed with cancer may be eligible for settlement benefits.
Depo-Provera Lawsuit Depo-Provera lawsuits are being investigated for women who developed meningioma brain tumors after receiving Depo-Provera birth control shots, claiming that Pfizer failed to adequately disclose side effects.
Ozempic Lawsuit Lawyers are pursuing Ozempic lawsuits, Wegovy lawsuits and Mounjaro lawsuits over gastroparesis or stomach paralysis, which can leave users with long-term gastrointestinal side effects
Suboxone Tooth Decay Lawsuit Lawsuits are being pursued by users of Suboxone who experienced tooth loss, broken teeth or required dental extractions. Settlement benefits may be available.
Change Healthcare Lawsuit Lawyers are reviewing Change Healthcare class action lawsuits for individuals who had their personal information stolen due to the data breach.
Bard PowerPort Lawsuit Serious and life-threatening injuries have been linked to problems with Bard PowerPort. Lawsuits are now being pursued by individuals who suffered injuries from the implantable port catheter fracturing or migrating.
AngioDynamics Port Catheter Lawsuit Serious and life-threatening injuries have been linked to problems with Bard PowerPort. Lawsuits are now being pursued by individuals who suffered injuries from the implantable port catheter fracturing or migrating.
Processed Food Lawsuit Lawsuits are being pursued against the food industry over their manufacturing and advertising of ultra-processed foods, which have caused a generation of children to face an increased risk of developing childhood diabetes and other chronic illnesses.
Reversal Agent for Pradaxa Works Within Minutes: Study June 23, 2015 Irvin Jackson Add Your Comments As Pradaxa lawsuits continue to be filed on behalf of individuals who have suffered uncontrollable bleeding problems, a new study suggests that a proposed reversal agent for the controversial anticoagulant may be able to stop the drug’s blood thinning effects within minutes, potentially allowing doctors to treat bleeding events that develop among users. According to a report published this week in the New England Journal of Medicine, the experimental drug idarucizumab reduced the blood thinning effects of Pradaxa (dabigatran) in virtually all test subjects. The study was sponsored by Boehringer Ingelheim and is the third phase of testing for the potential antidote, which may provide a substantial market advantage for the makers of Pradaxa, which is part of a new generation of oral anticoagulants that have been plagued by reports of uncontrollable bleeding due to a lack of safe and effective reversal agents. Learn More About Pradaxa Internal Bleeding Lawsuit Side effects of Pradaxa may increase risk of severe bleeding and death. Learn More SEE IF YOU QUALIFY FOR COMPENSATION Learn More About Pradaxa Internal Bleeding Lawsuit Side effects of Pradaxa may increase risk of severe bleeding and death. Learn More SEE IF YOU QUALIFY FOR COMPENSATION Pradaxa was the first member of a new class of mediations to hit the market in recent years, known as direct thrombin inhibitors. Other new-generation anticoagulants in the same class include Xarelto and Eliquis, which have all been aggressively marketed in recent years and quickly grown to become big selling medications. If approved, idarucizumab would make Pradaxa the first member of the class with a reversal agent, which may make the medication considerably safer. The drugs have been promoted as superior replacements for warfarin, which has been the go-to anticoagulant for prevention of strokes among patients with atrial fibrillation for years. While the manufacturers indicate that their drugs require less frequent blood monitoring, a large number of severe and sometimes bleeding problems have been linked to Pradaxa, Xarelto and Eliquis. Unlike warfarin, which can be quickly reversed with a dose of vitamin K and fresh frozen plasma if bleeding or hemorrhaging develops, each of the new generation of drugs were introduced without an approved reversal agents. The phase III study for the Pradaxa antidote is ongoing and will ultimately involve up to 300 patients at centers worldwide, according to Boehringer Ingelheim. The interim results were presented at the International Society of Thrombosis and Haemostasis 2015 Congress in Toronto, Canada. “Among 68 patients with an elevated dilute thrombin time and 81 with an elevated ecarin clotting time at baseline, the median maximum percentage reversal was 100% (95% confidence interval, 100 to 100),” the study’s findings note. “Idarucizumab normalized the test results in 88 to 98% of the patients, an effect that was evident within minutes.” The results indicate that after four and 12 hours, 90% of patients were at normal coagulation levels. However, there were 18 deaths among study subjects, primarily among those who were hospitalized for emergency bleeding events or other medical emergencies. “As observed in earlier research in volunteers, idarucizumab reversed the anticoagulant effect of dabigatran in patients completely within minutes,” lead investigator Dr. Charles Pollack, Professor of Emergency Medicine at the University of Pennsylvania’s Perelman School of Medicine, said in a Boehringer Ingelheim press release. “These data demonstrate that use of idarucizumab can help physicians focus on other vital aspects of emergency management beyond anticoagulant reversal in dabigatran-treated patients.” Lawsuits Over Pradaxa, Xarelto and Eliquis Since Boehringer Ingelheim introduced Pradaxa in October 2010, the drug maker has been hit with more than 4,000 product liability lawsuits alleging that inadequate warnings were provided about the bleeding risk and the lack of a reversal agent. Following several years of litigation, a Pradaxa settlement agreement was announced last year, with Boehringer Ingelheim agreeing to pay $650 million to resolve the claims for an average of about $150,000 each. However, the drug maker continues to face what appears to be a second round of Pradaxa bleeding lawsuits filed in recent months by individuals who have experienced problems since the original settlement. Xarelto (rivaroxoaban) was introduced in 2011, as the second member of this class, and it has since grown to become the best seller of the two. Bayer and Johnson & Johnson also face a growing number of Xarelto lawsuits, which raise nearly identical allegations from former users who suffered severe bleeding problems. Eliquis (apixaban) was approved by the FDA in early 2013, and Bristol-Myers Squibb has aggressively marketed the medication in direct-to-consumer advertisements to increase use, even though it also lacks a currently approved reversal agent. To date, Elquis has not been targeted by a large number of complaints or lawsuits, but that may change as its popularity increases. The FDA also recently announced the approval of a fourth member of this class, Savaysa (edoxaban), which will be marketed by Daiichi Sankyo. Many analysts have suggested that the first manufacturer to get a reversal agent approved by the FDA will have a significant market advantage over the competition. Tags: Bleeding, Blood Thinners, Boehringer Ingelheim, Coumadin, Eliquis, Pradaxa, Warfarin, Xarelto More Pradaxa Lawsuit Stories Jury Awards $540K in Pradaxa Trial Against Boehringer Ingelheim May 21, 2019 Paragard IUD Lawsuit Dismissed on Summary Judgment February 25, 2019 Boehringer Ingelheim Ordered to Pay $1.25M For Failure to Warn About Pradaxa Bleeding Risks October 25, 2018 0 Comments Share Your CommentsFirst Name*Last NameEmail* Shared Comments*This field is hidden when viewing the formI authorize the above comments be posted on this page Yes No Post Comment I authorize the above comments be posted on this page Weekly Digest Opt-In Yes, send me a weekly email with the latest lawsuits, recalls and warnings. Want your comments reviewed by a lawyer?To have an attorney review your comments and contact you about a potential case, provide your contact information below. This will not be published.Contact Phone #Alt Phone #Private CommentsNOTE: Providing information for review by an attorney does not form an attorney-client relationship.CAPTCHAGA SourceGA CampaignGA MediumGA ContentGA TermNameThis field is for validation purposes and should be left unchanged. Δ MORE TOP STORIES Reckitt Benckiser Faces Class Action Lawsuit Over Enfamil NEC Risks (Posted: today) A class action lawsuit filed against the makers of Enfamil say the company misled investors by concealing the fact that the cow’s milk-based infant formula increased the risk of NEC. 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Boehringer Ingelheim Ordered to Pay $1.25M For Failure to Warn About Pradaxa Bleeding Risks October 25, 2018
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